{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T12:54:34Z","timestamp":1780491274782,"version":"3.54.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006280","name":"Ministerio de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["2005SGR00315"],"award-info":[{"award-number":["2005SGR00315"]}],"id":[{"id":"10.13039\/501100006280","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["LSHB-CT-2004-504761"],"award-info":[{"award-number":["LSHB-CT-2004-504761"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["SAF2003-09353"],"award-info":[{"award-number":["SAF2003-09353"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.bbrc.2006.12.021","type":"journal-article","created":{"date-parts":[[2006,12,13]],"date-time":"2006-12-13T07:21:59Z","timestamp":1165994519000},"page":"381-388","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Transcription factors involved in the expression of SLC28 genes in human liver parenchymal cells"],"prefix":"10.1016","volume":"353","author":[{"given":"Sonia","family":"Fern\u00e1ndez-Veledo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramiro","family":"Jover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Javier","family":"Casado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"G\u00f3mez-Lech\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00e7al","family":"Pastor-Anglada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2006.12.021_bib","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1007\/s00424-003-1103-2","article-title":"The equilibrative nucleoside transporter family, SLC29","volume":"447","author":"Baldwin","year":"2004","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.bbrc.2006.12.021_bib2","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1007\/s00424-003-1107-y","article-title":"The concentrative nucleoside transporter family, SLC28","volume":"447","author":"Gray","year":"2004","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.bbrc.2006.12.021_bib3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1080\/096876800110033783","article-title":"Complex regulation of nucleoside transporter expression in epithelial and immune system cells","volume":"18","author":"Pastor-Anglada","year":"2001","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib4","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1042\/BST0330216","article-title":"The concentrative nucleoside transporter family (SLC28): new roles beyond salvage?","volume":"33","author":"Aymerich","year":"2005","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbrc.2006.12.021_bib5","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1006\/bbrc.1997.6498","article-title":"Expression of sodium-dependent purine nucleoside carrier (SPNT) mRNA correlates with nucleoside transport activity in rat liver","volume":"233","author":"Felipe","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2006.12.021_bib6","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1139\/o98-103","article-title":"Nucleoside transporters and liver cell growth","volume":"76","author":"Pastor-Anglada","year":"1998","journal-title":"Biochem. Cell Biol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib7","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1023\/A:1011945103455","article-title":"Intestinal absorption of ribavirin is preferentially mediated by the Na+-nucleoside purine (N1) transporter","volume":"15","author":"Patil","year":"1998","journal-title":"Pharm. Res."},{"issue":"Suppl. B","key":"10.1016\/j.bbrc.2006.12.021_bib8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/jac\/18.Supplement_B.207","article-title":"Improvement of the bioavailability of the anti-herpes virus agent BVDU by use of 5\u2032-O-alkoxycarbonyl derivatives with increased metabolic stability","volume":"18","author":"Boyd","year":"1986","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.bbrc.2006.12.021_bib9","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1002\/hep.510280609","article-title":"Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells","volume":"28","author":"del Santo","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2006.12.021_bib10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S0006-291X(02)00919-1","article-title":"Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs","volume":"296","author":"Valdes","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"Pt. 2","key":"10.1016\/j.bbrc.2006.12.021_bib11","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1042\/bj3300997","article-title":"Na+-dependent nucleoside transport in liver: two different isoforms from the same gene family are expressed in liver cells","volume":"330","author":"Felipe","year":"1998","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2006.12.021_bib12","doi-asserted-by":"crossref","first-page":"2710","DOI":"10.1128\/MCB.24.7.2710-2719.2004","article-title":"ATP-sensitive K(+) channels regulate the concentrative adenosine transporter CNT2 following activation by A(1) adenosine receptors","volume":"24","author":"Duflot","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib13","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1242\/jcs.02865","article-title":"Extracellular adenosine activates AMP-dependent protein kinase (AMPK)","volume":"119","author":"Aymerich","year":"2006","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbrc.2006.12.021_bib14","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0168-8278(01)00036-8","article-title":"Developmental regulation of the concentrative nucleoside transporters CNT1 and CNT2 in rat liver","volume":"34","author":"del Santo","year":"2001","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib15","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1053\/jhep.2000.9546","article-title":"Selective loss of nucleoside carrier expression in rat hepatocarcinomas","volume":"32","author":"Dragan","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2006.12.021_bib16","first-page":"165","article-title":"Cell cycle gene regulation in reversibly differentiated new human hepatoma cell lines","volume":"9","author":"Glaise","year":"1998","journal-title":"Cell Growth Differ."},{"key":"10.1016\/j.bbrc.2006.12.021_bib17","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1053\/jhep.2001.22176","article-title":"Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting","volume":"33","author":"Jover","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2006.12.021_bib18","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1124\/mol.63.5.1180","article-title":"Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma","volume":"63","author":"Rodriguez-Antona","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib19","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1182\/blood-2002-07-2236","article-title":"Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia","volume":"101","author":"Molina-Arcas","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2006.12.021_bib20","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0014-5793(98)00746-7","article-title":"Re-expression of C\/EBP alpha induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells","volume":"431","author":"Jover","year":"1998","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbrc.2006.12.021_bib21","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.jhep.2004.06.008","article-title":"Up-regulation of the high-affinity pyrimidine-preferring nucleoside transporter concentrative nucleoside transporter 1 by tumor necrosis factor-alpha and interleukin-6 in liver parenchymal cells","volume":"41","author":"Fernandez-Veledo","year":"2004","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib22","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1046\/j.1432-1327.2001.02011.x","article-title":"Expression and induction of a large set of drug-metabolizing enzymes by the highly differentiated human hepatoma cell line BC2","volume":"268","author":"Gomez-Lechon","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbrc.2006.12.021_bib23","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1128\/MCB.17.4.1913","article-title":"Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells","volume":"17","author":"Spath","year":"1997","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib24","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1006\/geno.1994.1191","article-title":"The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution","volume":"20","author":"Kaestner","year":"1994","journal-title":"Genomics"},{"key":"10.1016\/j.bbrc.2006.12.021_bib25","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S1097-2765(02)00459-8","article-title":"Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4","volume":"9","author":"Cirillo","year":"2002","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbrc.2006.12.021_bib26","doi-asserted-by":"crossref","first-page":"17174","DOI":"10.1016\/S0021-9258(17)44885-X","article-title":"Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A","volume":"265","author":"Yoshida","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2006.12.021_bib27","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1085\/jgp.200409086","article-title":"Long term endocrine regulation of nucleoside transporters in rat intestinal epithelial cells","volume":"124","author":"Aymerich","year":"2004","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.bbrc.2006.12.021_bib28","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1096\/fj.01-0022com","article-title":"Macrophages require different nucleoside transport systems for proliferation and activation","volume":"15","author":"Soler","year":"2001","journal-title":"FASEB J."},{"key":"10.1016\/j.bbrc.2006.12.021_bib29","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1006\/excr.2002.5641","article-title":"Concentrative nucleoside transporter (rCNT1) is targeted to the apical membrane through the hepatic transcytotic pathway","volume":"281","author":"Duflot","year":"2002","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.bbrc.2006.12.021_bib30","doi-asserted-by":"crossref","DOI":"10.1007\/s00018-006-6240-2","article-title":"TGF-beta transcriptionally activates the gene encoding the high-affinity adenosine transporter CNT2 in rat liver parenchymal cells","author":"Valdes","year":"2006","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbrc.2006.12.021_bib31","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1101\/gad.14.4.464","article-title":"Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha","volume":"14","author":"Li","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbrc.2006.12.021_bib32","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1126\/science.7652557","article-title":"Impaired energy homeostasis in C\/EBP alpha knockout mice","volume":"269","author":"Wang","year":"1995","journal-title":"Science"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X06026787?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X06026787?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T10:32:01Z","timestamp":1757759521000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X06026787"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S0006291X06026787"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2006.12.021","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcription factors involved in the expression of SLC28 genes in human liver parenchymal cells","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2006.12.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}