{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:20:44Z","timestamp":1790234444596,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1016\/j.bbrc.2007.04.114","type":"journal-article","created":{"date-parts":[[2007,4,27]],"date-time":"2007-04-27T11:13:42Z","timestamp":1177672422000},"page":"241-246","source":"Crossref","is-referenced-by-count":51,"title":["Differential expression of galectins in normal, benign and malignant prostate epithelial cells: Silencing of galectin-3 expression in prostate cancer by its promoter methylation"],"prefix":"10.1016","volume":"358","author":[{"given":"Hafiz","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Partha P.","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo R.","family":"Vasta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2007.04.114_bib1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/nrc1527","article-title":"Galectins as modulators of tumour progression","volume":"5","author":"Liu","year":"2005","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.bbrc.2007.04.114_bib2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s10495-005-0801-y","article-title":"On the role of galectin-3 in cancer apoptosis","volume":"10","author":"Nakahara","year":"2005","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbrc.2007.04.114_bib3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0304-4165(02)00310-0","article-title":"Galectinomics: a lesson in complexity","volume":"1572","author":"Cooper","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbrc.2007.04.114_bib4","first-page":"6239","article-title":"The NH2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells","volume":"59","author":"Gong","year":"1999","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2007.04.114_bib5","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2174\/156800906778194568","article-title":"Knowledge of epigenetic influence for prostate cancer therapy","volume":"6","author":"Watanabe","year":"2006","journal-title":"Curr. Cancer Drug Targets"},{"key":"10.1016\/j.bbrc.2007.04.114_bib6","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1023\/B:GLYC.0000014083.48508.6a","article-title":"Expression of galectins in cancer: a critical review","volume":"19","author":"van den Brule","year":"2004","journal-title":"Glycoconj. J."},{"key":"10.1016\/j.bbrc.2007.04.114_bib7","first-page":"815","article-title":"Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications","volume":"147","author":"Xu","year":"1995","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbrc.2007.04.114_bib8","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/ajcp\/111.5.623","article-title":"Galectin fingerprinting in tumor diagnosis. Differential expression of galectin-3 and galectin-3 binding sites, but not galectin-1, in benign vs malignant uterine smooth muscle tumors","volume":"111","author":"Schwarz","year":"1999","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.bbrc.2007.04.114_bib9","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1002\/(SICI)1097-0142(19991201)86:11<2353::AID-CNCR25>3.0.CO;2-A","article-title":"The levels of expression of galectin-1, galectin-3, and the Thomsen-Friedenreich antigen and their binding sites decrease as clinical aggressiveness increases in head and neck cancers","volume":"86","author":"Choufani","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.bbrc.2007.04.114_bib10","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/ijc.2910560404","article-title":"Expression of a 31-kDa lactoside-binding lectin in normal human gastric mucosa and in primary and metastatic gastric carcinomas","volume":"56","author":"Lotan","year":"1994","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2007.04.114_bib11","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/(SICI)1097-0215(19990517)81:4<519::AID-IJC3>3.0.CO;2-0","article-title":"Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma","volume":"81","author":"Hsu","year":"1999","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2007.04.114_bib12","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1007\/s002400050164","article-title":"Galectin-1 and galectin-3 expression in human prostate tissue and prostate cancer","volume":"27","author":"Ellerhorst","year":"1999","journal-title":"Urol. Res."},{"key":"10.1016\/j.bbrc.2007.04.114_bib13","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/1097-0045(20000701)44:2<118::AID-PROS4>3.0.CO;2-U","article-title":"Decreased galectin-3 expression in prostate cancer","volume":"44","author":"Pacis","year":"2000","journal-title":"Prostate"},{"key":"10.1016\/j.bbrc.2007.04.114_bib14","doi-asserted-by":"crossref","first-page":"7252","DOI":"10.1073\/pnas.93.14.7252","article-title":"Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family","volume":"93","author":"Su","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2007.04.114_bib15","first-page":"861","article-title":"Immunohistochemical profile of galectin-8 expression in benign and malignant tumors of epithelial, mesenchymatous and adipous origins, and of the nervous system","volume":"16","author":"Danguy","year":"2001","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.bbrc.2007.04.114_bib16","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.bbagen.2005.12.020","article-title":"Galectin-3: an open-ended story","volume":"1760","author":"Dumic","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbrc.2007.04.114_bib17","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1158\/0008-5472.CAN-04-3578","article-title":"Effects of DNA methylation on galectin-3 expression in pituitary tumors","volume":"65","author":"Ruebel","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2007.04.114_bib18","first-page":"843","article-title":"Methylation of TFPI-2 gene is not the sole cause of its silencing","volume":"22","author":"Rao","year":"2003","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.bbrc.2007.04.114_bib19","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1073\/pnas.89.5.1827","article-title":"A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands","volume":"89","author":"Frommer","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2007.04.114_bib20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1006\/abbi.1997.0447","article-title":"The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter","volume":"349","author":"Kadrofske","year":"1998","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbrc.2007.04.114_bib21","series-title":"Molecular Cloning. A Laboratory Manual","author":"Sambrook","year":"1989"},{"key":"10.1016\/j.bbrc.2007.04.114_bib22","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0378-1119(01)00598-4","article-title":"Two messenger RNAs and five isoforms for Po66-CBP, a galectin-8 homolog in a human lung carcinoma cell line","volume":"274","author":"Bidon","year":"2001","journal-title":"Gene"},{"key":"10.1016\/j.bbrc.2007.04.114_bib23","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1023\/B:GLYC.0000014086.38343.98","article-title":"Human galectin-8 isoforms and cancer","volume":"19","author":"Bidon-Wagner","year":"2004","journal-title":"Glycoconj. J."},{"key":"10.1016\/j.bbrc.2007.04.114_bib24","first-page":"516","article-title":"Role of galectin-8 as a modulator of cell adhesion and cell growth","volume":"19","author":"Zick","year":"2004","journal-title":"Glycoconj. J."},{"key":"10.1016\/j.bbrc.2007.04.114_bib25","doi-asserted-by":"crossref","first-page":"7527","DOI":"10.1038\/sj.onc.1207997","article-title":"Dual activities of galectin-3 in human prostate cancer: tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3","volume":"23","author":"Califice","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2007.04.114_bib26","first-page":"2999","article-title":"Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis","volume":"62","author":"Kim","year":"2002","journal-title":"Cancer Res."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X07008352?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X07008352?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T23:57:10Z","timestamp":1546905430000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X07008352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["S0006291X07008352"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2007.04.114","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}