{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T06:47:14Z","timestamp":1785826034812,"version":"3.56.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1016\/j.bbrc.2007.10.046","type":"journal-article","created":{"date-parts":[[2007,11,8]],"date-time":"2007-11-08T12:35:58Z","timestamp":1194525358000},"page":"650-655","source":"Crossref","is-referenced-by-count":28,"title":["Molecular response to phototoxic stress of UVB-irradiated ketoprofen through arresting cell cycle in G2\/M phase and inducing apoptosis"],"prefix":"10.1016","volume":"364","author":[{"given":"Shicheng","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Mizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Yamauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2007.10.046_bib1","doi-asserted-by":"crossref","first-page":"13525","DOI":"10.1074\/jbc.M512694200","article-title":"Human keratinocytes acquire cellular cytotoxicity under UV-B irradiation. Implication of granzyme B and perforin","volume":"281","author":"Hernandez-Pigeon","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2007.10.046_bib2","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1046\/j.1523-1747.2003.12495.x","article-title":"Epidermal COX-2 induction following ultraviolet irradiation: suggested mechanism for the role of COX-2 inhibition in photoprotection","volume":"121","author":"Tripp","year":"2003","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.bbrc.2007.10.046_bib3","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S1011-1344(01)00198-1","article-title":"The epidemiology of UV induced skin cancer","volume":"63","author":"Armstrong","year":"2001","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.bbrc.2007.10.046_bib4","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1038\/sj.onc.1206537","article-title":"Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer","volume":"22","author":"Dazard","year":"2003","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2007.10.046_bib5","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1124\/jpet.105.088674","article-title":"Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor kappaB inhibitor, parthenolide","volume":"315","author":"Tanaka","year":"2005","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.bbrc.2007.10.046_bib6","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/379335a0","article-title":"Molecular basis of sun-induced premature skin ageing and retinoid antagonism","volume":"379","author":"Fisher","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2007.10.046_bib7","first-page":"4","article-title":"UV radiation-induced immunosuppression and skin cancer","volume":"74","author":"Granstein","year":"2004","journal-title":"Cutis"},{"key":"10.1016\/j.bbrc.2007.10.046_bib8","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.taap.2003.08.019","article-title":"Toxic effects of ultraviolet radiation on the skin","volume":"195","author":"Matsumura","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbrc.2007.10.046_bib9","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.1038\/sj.onc.1209384","article-title":"Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance","volume":"25","author":"He","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2007.10.046_bib10","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/246217a0","article-title":"Prostaglandins, aspirin-like drugs and the oedema of inflammation","volume":"246","author":"Moncada","year":"1973","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2007.10.046_bib11","doi-asserted-by":"crossref","first-page":"339","DOI":"10.2165\/00002018-200022050-00002","article-title":"Photosensitivity to ketoprofen: mechanisms and pharmacoepidemiological data","volume":"22","author":"Bagheri","year":"2000","journal-title":"Drug Saf."},{"key":"10.1016\/j.bbrc.2007.10.046_bib12","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.0105-1873.2005.00498d.x","article-title":"Allergic contact dermatitis from topical piketoprofen","volume":"52","author":"Rodriguez-Lozano","year":"2005","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.bbrc.2007.10.046_bib13","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1111\/j.1751-1097.1998.tb02529.x","article-title":"Comparison of the DNA damage photoinduced by fenofibrate and ketoprofen, two phototoxic drugs of parent structure","volume":"68","author":"Marguery","year":"1998","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2007.10.046_bib14","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/1011-1344(95)07181-4","article-title":"Evaluation of ketoprofen (R,S and R\/S) phototoxicity by a battery of in vitro assays","volume":"31","author":"Bosca","year":"1995","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.bbrc.2007.10.046_bib15","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1562\/0031-8655(2003)077<0390:PADNAD>2.0.CO;2","article-title":"Prompt and delayed nonsteroidal anti-inflammatory drug-photoinduced DNA damage in peripheral blood mononuclear cells measured with the comet assays","volume":"77","author":"Vinette","year":"2003","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2007.10.046_bib16","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.0105-1873.2005.00778.x","article-title":"Photoallergic contact dermatitis from ketoprofen in southern Sweden","volume":"54","author":"Hindsen","year":"2006","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.bbrc.2007.10.046_bib17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.bbrc.2006.09.166","article-title":"Hinokitiol, a metal chelator derived from natural plants, suppresses cell growth and disrupts androgen receptor signaling in prostate carcinoma cell lines","volume":"351","author":"Liu","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2007.10.046_bib18","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s000180050171","article-title":"Mechanisms controlling cellular suicide: role of Bcl-2 and caspases","volume":"54","author":"Allen","year":"1998","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.bbrc.2007.10.046_bib19","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1562\/0031-8655(2001)074<0670:CODDPB>2.0.CO;2","article-title":"Comparison of DNA damage photoinduced by ketoprofen, fenofibric acid and benzophenone via electron and energy transfer","volume":"74","author":"Lhiaubet","year":"2001","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bbrc.2007.10.046_bib20","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1046\/j.1365-2125.1996.41420.x","article-title":"Patient awareness of the adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs)","volume":"42","author":"Wynne","year":"1996","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.bbrc.2007.10.046_bib21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1006\/bbrc.2000.3436","article-title":"Mechanism of ultraviolet B-induced cell cycle arrest in G2\/M phase in immortalized skin keratinocytes with defective p53","volume":"277","author":"Athar","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2007.10.046_bib22","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1111\/j.0022-202X.2004.22522.x","article-title":"Keratinocyte G2\/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation","volume":"122","author":"Dai","year":"2004","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.bbrc.2007.10.046_bib23","doi-asserted-by":"crossref","first-page":"3965","DOI":"10.1091\/mbc.E03-12-0871","article-title":"p21-mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress","volume":"15","author":"Charrier-Savournin","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbrc.2007.10.046_bib24","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1038\/sj.onc.1202667","article-title":"Association with Cdc2 and inhibition of Cdc2\/Cyclin B1 kinase activity by the p53-regulated protein Gadd45","volume":"18","author":"Zhan","year":"1999","journal-title":"Oncogene"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X07022206?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X07022206?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T02:57:31Z","timestamp":1546484251000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X07022206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["S0006291X07022206"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2007.10.046","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]}}}