{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T12:40:01Z","timestamp":1772196001301,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.bbrc.2008.11.061","type":"journal-article","created":{"date-parts":[[2008,11,26]],"date-time":"2008-11-26T08:23:54Z","timestamp":1227687834000},"page":"456-461","source":"Crossref","is-referenced-by-count":19,"title":["Expression of cardiac function genes in adult stem cells is increased by treatment with nitric oxide agents"],"prefix":"10.1016","volume":"378","author":[{"given":"Carmen K.","family":"Rebelatto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra M.","family":"Aguiar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra C.","family":"Senegaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos M.","family":"Aita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiane","family":"Barchiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crisciele","family":"Kuligovski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcia","family":"Olandoski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 A.","family":"Moutinho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Dallagiovanna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo S.","family":"Brofman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lia S.","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2008.11.061_bib1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1097\/00002727-200701000-00009","article-title":"Cardiac cell therapy: a treatment option for cardiomyopathy","volume":"30","author":"Shepler","year":"2007","journal-title":"Crit. Care Nurs. Q"},{"issue":"Suppl. 1","key":"10.1016\/j.bbrc.2008.11.061_bib2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1365-2184.2008.00480.x","article-title":"The therapeutic potential of stem cells in heart disease","volume":"41","author":"Strauer","year":"2008","journal-title":"Cell Prolif."},{"key":"10.1016\/j.bbrc.2008.11.061_bib3","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1172\/JCI200522326","article-title":"Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction","volume":"115","author":"Yoon","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2008.11.061_bib4","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/S0301-472X(02)00869-X","article-title":"Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain","volume":"30","author":"Jiang","year":"2002","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.bbrc.2008.11.061_bib5","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1161\/hc0102.101442","article-title":"Human mesenchymal stem cells differentiate of a cardiomyocyte phenotype in the adult murine heart","volume":"105","author":"Toma","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2008.11.061_bib6","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s10517-006-0403-x","article-title":"In vitro and in vivo differentiation of mesenchymal stem cells in the cardiomyocyte direction","volume":"142","author":"Kruglyakov","year":"2006","journal-title":"Bull. Exp. Biol. Med."},{"key":"10.1016\/j.bbrc.2008.11.061_bib7","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1510\/icvts.2007.157875","article-title":"In vitro cardiomyogenic differentiation of adult human bone marrow mesenchymal stem cells. The role of 5-azacytidine","volume":"6","author":"Antonitsis","year":"2007","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"key":"10.1016\/j.bbrc.2008.11.061_bib8","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ijcard.2005.05.072","article-title":"Cell-to-cell contact induces mesenchymal stem cell to differentiate into cardiomyocyte and smooth muscle cell","volume":"109","author":"Wang","year":"2006","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbrc.2008.11.061_bib9","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1634\/stemcells.2006-0662","article-title":"The significant cardiomyogenic potential of human umbilical cord blood-derived mesenchymal stem cells in vitro","volume":"25","author":"Nishiyama","year":"2007","journal-title":"Stem Cells"},{"key":"10.1016\/j.bbrc.2008.11.061_bib10","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.bbrc.2004.09.087","article-title":"Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells","volume":"324","author":"Shim","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2008.11.061_bib11","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1111\/j.1745-7254.2006.00436.x","article-title":"Differentiation of bone marrow mesenchymal stem cells induced by myocardial medium under hypoxic conditions","volume":"27","author":"Xie","year":"2006","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.bbrc.2008.11.061_bib12","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1177\/014107689909200402","article-title":"Nitric oxide: discovery and impact on clinical medicine","volume":"92","author":"Moncada","year":"1999","journal-title":"J. R. Soc. Med."},{"key":"10.1016\/j.bbrc.2008.11.061_bib13","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1634\/stemcells.2005-0640","article-title":"Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis","volume":"24","author":"Covacu","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.bbrc.2008.11.061_bib14","doi-asserted-by":"crossref","first-page":"H1760","DOI":"10.1152\/ajpheart.01408.2006","article-title":"Endothelial nitric oxide synthase is dynamically expressed during bone marrow stem cell differentiation into endothelial cells","volume":"293","author":"Liu","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbrc.2008.11.061_bib15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ejphar.2008.06.066","article-title":"Nitric oxide enhances Oct-4 expression in bone marrow stem cells and promotes endothelial differentiation","volume":"591","author":"Chu","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2008.11.061_bib16","doi-asserted-by":"crossref","first-page":"12277","DOI":"10.1073\/pnas.0401557101","article-title":"Nitric oxide facilitates cardiomyogenesis in mouse embryonic stem cells","volume":"101","author":"Kanno","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2008.11.061_bib17","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/01.CIR.0000024114.82981.EA","article-title":"Development of heart failure and congenital septal defects in mice lacking endothelial nitric oxide synthase","volume":"106","author":"Feng","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2008.11.061_bib18","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0008-6363(99)00160-1","article-title":"Nitric oxide synthase expression and role during cardiomyogenesis","volume":"43","author":"Bloch","year":"1999","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbrc.2008.11.061_bib19","doi-asserted-by":"crossref","first-page":"901","DOI":"10.3181\/0712-RM-356","article-title":"Dissimilar differentiation potential of mesenchymal stem cells isolated from bone marrow, umbilical cord blood and adipose tissue","volume":"233","author":"Rebelatto","year":"2008","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.bbrc.2008.11.061_bib20","series-title":"Antibodies, A laboratory manual","author":"Harlow","year":"1988"},{"key":"10.1016\/j.bbrc.2008.11.061_bib21","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S1079-9796(03)00150-5","article-title":"Multilineage gene expression in human bone marrow stromal cells as evidenced by single-cell microarray analysis","volume":"31","author":"Seshi","year":"2003","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.bbrc.2008.11.061_bib22","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.bbrc.2007.08.033","article-title":"Pluripotent marker expression and differentiation of human second trimester mesenchymal stem cells","volume":"362","author":"Gonzalez","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2008.11.061_bib23","doi-asserted-by":"crossref","unstructured":"W.C. Lee, J.L. Sepulveda, J.P. Rubin, K.G. Marra, Cardiomyogenic differentiation potential of human adipose precursor cells, Int. J. Cardiol. (2008), doi: 10.1016\/j.ijcard.2007.11.068.","DOI":"10.1016\/j.ijcard.2007.11.068"},{"key":"10.1016\/j.bbrc.2008.11.061_bib24","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1432-0436.2004.07207003.x","article-title":"Bone marrow-derived mesenchymal stem cells already express specific neural proteins before any differentiation","volume":"72","author":"Tondreau","year":"2004","journal-title":"Differentiation"},{"key":"10.1016\/j.bbrc.2008.11.061_bib25","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.cell.2004.09.030","article-title":"Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation","volume":"119","author":"Sampath","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2008.11.061_bib26","doi-asserted-by":"crossref","first-page":"4055","DOI":"10.1182\/blood-2006-10-051060","article-title":"MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines","volume":"109","author":"Ries","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2008.11.061_bib27","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1161\/ATVBAHA.107.147256","article-title":"Late-outgrowth endothelial cells attenuate intimal hyperplasia contributed by mesenchymal stem cells after vascular injury","volume":"28","author":"Wang","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bbrc.2008.11.061_bib28","doi-asserted-by":"crossref","first-page":"5826","DOI":"10.1038\/sj.emboj.7601441","article-title":"TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration","volume":"25","author":"Girgenrath","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2008.11.061_bib29","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1634\/stemcells.2006-0174","article-title":"Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia","volume":"24","author":"Coyne","year":"2006","journal-title":"Stem Cells"},{"issue":"Suppl. 1","key":"10.1016\/j.bbrc.2008.11.061_bib30","first-page":"II253","article-title":"Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model","volume":"108","author":"Davani","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2008.11.061_bib31","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1161\/CIRCULATIONAHA.104.527937","article-title":"Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects","volume":"112","author":"Dai","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2008.11.061_bib32","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.jtcvs.2007.07.028","article-title":"Comparative effects of mesenchymal progenitor cells, endothelial progenitor cells, or their combination on myocardial infarct regeneration and cardiac function","volume":"134","author":"Suuronen","year":"2007","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.bbrc.2008.11.061_bib33","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1006\/cyto.1999.0580","article-title":"Effect of cytokines and growth factors on the macrophage colony-stimulating factor secretion by human bone marrow stromal cells","volume":"12","author":"Besse","year":"2000","journal-title":"Cytokine"},{"key":"10.1016\/j.bbrc.2008.11.061_bib34","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1161\/hc3501.093817","article-title":"Implantation of bone-marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokines","volume":"104","author":"Kamihata","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2008.11.061_bib35","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1161\/01.HYP.0000053552.86367.12","article-title":"Enhancement of ischemia-induced angiogenesis by eNOS overexpression","volume":"41","author":"Amano","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.bbrc.2008.11.061_bib36","doi-asserted-by":"crossref","first-page":"13801","DOI":"10.1073\/pnas.250488097","article-title":"Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart","volume":"97","author":"Su","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2008.11.061_bib37","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1182\/blood.V94.8.2548.420k38_2548_2554","article-title":"Reversible expression of CD34 by murine hematopoietic stem cells","volume":"94","author":"Sato","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2008.11.061_bib38","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.ijcard.2005.06.043","article-title":"Endogenous G-CSF and CD34+ cell mobilization after acute myocardial infarction","volume":"111","author":"Leone","year":"2006","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbrc.2008.11.061_bib39","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.bbrc.2003.12.109","article-title":"Differentiation of human adipose tissue stem cells using extracts of rat cardiomyocytes","volume":"314","author":"Gaustad","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2008.11.061_bib40","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1634\/stemcells.2004-0252","article-title":"High-efficiency RNA interference in human embryonic stem cells","volume":"23","author":"Zaehres","year":"2005","journal-title":"Stem Cells"},{"key":"10.1016\/j.bbrc.2008.11.061_bib41","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1634\/stemcells.2005-0363","article-title":"Gap junction protein connexin 43 serves as a negative marker for a stem cell-containing population of human limbal epithelial cells","volume":"24","author":"Chen","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.bbrc.2008.11.061_bib42","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1432-0436.2006.00063.x","article-title":"Enhanced differentiation of human embryonic stem cells into cardiomyocytes by combining hanging drop culture and 5-azacytidine treatment","volume":"74","author":"Yoon","year":"2006","journal-title":"Differentiation"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X08022560?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X08022560?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T10:30:14Z","timestamp":1709461814000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X08022560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0006291X08022560"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2008.11.061","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}