{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:47:51Z","timestamp":1761155271506},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.bbrc.2009.01.060","type":"journal-article","created":{"date-parts":[[2009,1,24]],"date-time":"2009-01-24T04:21:33Z","timestamp":1232770893000},"page":"286-291","source":"Crossref","is-referenced-by-count":31,"title":["Over-expression of C\/EBP-\u03b1 induces apoptosis in cultured rat hepatic stellate cells depending on p53 and peroxisome proliferator-activated receptor-\u03b3"],"prefix":"10.1016","volume":"380","author":[{"given":"Xueqing","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangcun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Mei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juling","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinsheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2009.01.060_bib1","first-page":"101","article-title":"Hepatic stellate cells","volume":"14","author":"Friedman","year":"1996","journal-title":"Prog. Liver Dis."},{"key":"10.1016\/j.bbrc.2009.01.060_bib2","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1096\/fasebj.5.3.2001786","article-title":"Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis","volume":"5","author":"Blomhoff","year":"1991","journal-title":"FASEB J."},{"key":"10.1016\/j.bbrc.2009.01.060_bib3","first-page":"193","article-title":"Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture","volume":"24","author":"Rockey","year":"1992","journal-title":"J. Submicrosc. Cytol. Pathol."},{"key":"10.1016\/j.bbrc.2009.01.060_bib4","doi-asserted-by":"crossref","first-page":"7276","DOI":"10.1073\/pnas.96.13.7276","article-title":"Separation of C\/EBPalpha-mediated proliferation arrest and differentiation pathways","volume":"96","author":"Muller","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2009.01.060_bib5","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1242\/jcs.02459","article-title":"Molecular stop signs: regulation of cell-cycle arrest by C\/EBP transcription factors","volume":"118","author":"Johnson","year":"2005","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbrc.2009.01.060_bib6","doi-asserted-by":"crossref","first-page":"29200","DOI":"10.1074\/jbc.M011587200","article-title":"CCAAT\/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding","volume":"276","author":"Harris","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2009.01.060_bib7","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.bbrc.2004.09.196","article-title":"Involvement of C\/EBP-alpha gene in in vitro activation of rat hepatic stellate cells","volume":"324","author":"Huang","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2009.01.060_bib8","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.1872-034X.2007.00074.x","article-title":"In vivo transfection of C\/EBP-alpha gene could ameliorate CCL(4)-induced hepatic fibrosis in mice","volume":"37","author":"Mei","year":"2007","journal-title":"Hepatol. Res."},{"key":"10.1016\/j.bbrc.2009.01.060_bib9","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1172\/JCI1018","article-title":"Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors","volume":"102","author":"Iredale","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2009.01.060_bib10","first-page":"528","article-title":"Down-regulation and antiproliferative role of C\/EBPalpha in lung cancer","volume":"62","author":"Halmos","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2009.01.060_bib11","doi-asserted-by":"crossref","first-page":"30535","DOI":"10.1074\/jbc.M704829200","article-title":"Tamoxifen induction of CCAAT enhancer-binding protein alpha is required for tamoxifen-induced apoptosis","volume":"282","author":"Cheng","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2009.01.060_bib12","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/hep.510310122","article-title":"Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells","volume":"31","author":"Ankoma-Sey","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2009.01.060_bib13","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1365-2613.2006.00466.x","article-title":"Adrenomedullin regulates expressions of transforming growth factor-beta1 and beta1-induced matrix metalloproteinase-2 in hepatic stellate cells","volume":"87","author":"Wang","year":"2006","journal-title":"Int. J. Exp. Pathol."},{"key":"10.1016\/j.bbrc.2009.01.060_bib14","first-page":"1265","article-title":"CD95\/CD95L-mediated apoptosis of the hepatic stellate cell. A mechanism terminating uncontrolled hepatic stellate cell proliferation during hepatic tissue repair","volume":"151","author":"Saile","year":"1997","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbrc.2009.01.060_bib15","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/hep.510300144","article-title":"Transforming growth factor beta and tumor necrosis factor alpha inhibit both apoptosis and proliferation of activated rat hepatic stellate cells","volume":"30","author":"Saile","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2009.01.060_bib16","doi-asserted-by":"crossref","first-page":"99","DOI":"10.5551\/jat.10.99","article-title":"Apoptosis of endothelial cells may be mediated by genes of peroxisome proliferator-activated receptor gamma 1 (PPARgamma 1) and PPARalpha genes","volume":"10","author":"Inoue","year":"2003","journal-title":"J. Atheroscler. Thromb."},{"key":"10.1016\/j.bbrc.2009.01.060_bib17","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1210\/me.2006-0192","article-title":"Peroxisome proliferator-activated receptor-gamma activates p53 gene promoter binding to the nuclear factor-kappaB sequence in human MCF7 breast cancer cells","volume":"20","author":"Bonofiglio","year":"2006","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.bbrc.2009.01.060_bib18","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev.immunol.21.120601.141029","article-title":"Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more","volume":"21","author":"Marsden","year":"2003","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.bbrc.2009.01.060_bib19","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1084\/jem.188.11.2033","article-title":"P53 activates the CD95 (APO-1\/Fas) gene in response to DNA damage by anticancer drugs","volume":"188","author":"Muller","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbrc.2009.01.060_bib20","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1126\/science.277.5327.815","article-title":"An antagonist decoy receptor and a death domain-containing receptor for TRAIL","volume":"277","author":"Pan","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2009.01.060_bib21","doi-asserted-by":"crossref","first-page":"5386","DOI":"10.1093\/emboj\/16.17.5386","article-title":"TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL","volume":"16","author":"Walczak","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2009.01.060_bib22","first-page":"1593","article-title":"P53-dependent and -independent regulation of the death receptor KILLER\/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha","volume":"58","author":"Sheikh","year":"1998","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2009.01.060_bib23","doi-asserted-by":"crossref","first-page":"5078","DOI":"10.1158\/0008-5472.CAN-04-1195","article-title":"P53 upregulates death receptor 4 expression through an intronic p53 binding site","volume":"64","author":"Liu","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2009.01.060_bib24","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/35042675","article-title":"Surfing the p53 network","volume":"408","author":"Vogelstein","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2009.01.060_bib25","first-page":"2483","article-title":"RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria","volume":"63","author":"Yu","year":"2003","journal-title":"Cancer Res."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X09000990?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X09000990?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T03:15:26Z","timestamp":1549595726000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X09000990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0006291X09000990"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2009.01.060","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}