{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:47:01Z","timestamp":1791085621394,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1016\/j.bbrc.2009.12.001","type":"journal-article","created":{"date-parts":[[2009,12,12]],"date-time":"2009-12-12T04:17:58Z","timestamp":1260591478000},"page":"979-983","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Essential role of TRPC1 channels in cardiomyoblasts hypertrophy mediated by 5-HT2A serotonin receptors"],"prefix":"10.1016","volume":"391","author":[{"given":"C\u00e9cile","family":"Vindis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romina","family":"D\u2019Angelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Mucher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"N\u00e8gre-Salvayre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Parini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"Mialet-Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2009.12.001_bib1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1159\/000205962","article-title":"Disrupted serotonergic and sympathoadrenal systems in patients with chronic heart failure may serve as new therapeutic targets and novel biomarkers to assess severity, progression and response to treatment","volume":"113","author":"Nigmatullina","year":"2009","journal-title":"Cardiology"},{"key":"10.1016\/j.bbrc.2009.12.001_bib2","first-page":"153","article-title":"Serotonergic mechanisms in heart failure","volume":"46","author":"Chandra","year":"1994","journal-title":"Indian Heart J."},{"key":"10.1016\/j.bbrc.2009.12.001_bib3","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.yjmcc.2007.08.019","article-title":"Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle","volume":"43","author":"Brattelid","year":"2007","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"Suppl. 1","key":"10.1016\/j.bbrc.2009.12.001_bib4","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF00053431","article-title":"Effects of ketanserin on left ventricular hypertrophy in hypertensive patients","volume":"4","author":"Cobo","year":"1990","journal-title":"Cardiovasc. Drugs Ther."},{"key":"10.1016\/j.bbrc.2009.12.001_bib5","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.yjmcc.2008.12.017","article-title":"Genetic deletion of MAO-A promotes serotonin-dependent ventricular hypertrophy by pressure overload","volume":"46","author":"Lairez","year":"2009","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbrc.2009.12.001_bib6","doi-asserted-by":"crossref","first-page":"H821","DOI":"10.1152\/ajpheart.00345.2009","article-title":"Dose-dependent activation of distinct hypertrophic pathways by serotonin in cardiac cells","volume":"297","author":"Villeneuve","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbrc.2009.12.001_bib7","doi-asserted-by":"crossref","first-page":"2870","DOI":"10.1073\/pnas.0308723101","article-title":"A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway","volume":"101","author":"Bush","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2009.12.001_bib8","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1161\/01.RES.0000109415.17511.18","article-title":"Calcineurin\/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy","volume":"94","author":"Wilkins","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbrc.2009.12.001_bib9","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.pharmthera.2008.03.008","article-title":"TRP channel and cardiovascular disease","volume":"118","author":"Watanabe","year":"2008","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbrc.2009.12.001_bib10","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1440-1681.2005.04251.x","article-title":"Emerging functions of 10 types of TRP cationic channel in vascular smooth muscle","volume":"32","author":"Beech","year":"2005","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.bbrc.2009.12.001_bib11","doi-asserted-by":"crossref","first-page":"33487","DOI":"10.1074\/jbc.M605536200","article-title":"Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling","volume":"281","author":"Bush","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2009.12.001_bib12","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1096\/fj.05-5560com","article-title":"Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart","volume":"20","author":"Nakayama","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.bbrc.2009.12.001_bib13","doi-asserted-by":"crossref","first-page":"5305","DOI":"10.1038\/sj.emboj.7601417","article-title":"TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy","volume":"25","author":"Onohara","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2009.12.001_bib14","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1172\/JCI27702","article-title":"TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling","volume":"116","author":"Kuwahara","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2009.12.001_bib15","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.yjmcc.2006.10.020","article-title":"Upregulation of TRPC1 in the development of cardiac hypertrophy","volume":"42","author":"Ohba","year":"2007","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbrc.2009.12.001_bib16","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s00210-004-0980-z","article-title":"Urotensin-II-mediated cardiomyocyte hypertrophy: effect of receptor antagonism and role of inflammatory mediators","volume":"370","author":"Johns","year":"2004","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.bbrc.2009.12.001_bib17","doi-asserted-by":"crossref","first-page":"32562","DOI":"10.1074\/jbc.M801904200","article-title":"Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase","volume":"283","author":"Stuck","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2009.12.001_bib18","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s00210-008-0321-8","article-title":"Roles of TRP channels in the development of cardiac hypertrophy","volume":"378","author":"Nishida","year":"2008","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.bbrc.2009.12.001_bib19","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1096\/fj.04-2518fje","article-title":"A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation","volume":"19","author":"Bianchi","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.bbrc.2009.12.001_bib20","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1161\/CIRCRESAHA.109.206581","article-title":"TRPC1 channels are critical for hypertrophic signaling in the heart","volume":"105","author":"Seth","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbrc.2009.12.001_bib21","doi-asserted-by":"crossref","first-page":"H245","DOI":"10.1152\/ajpheart.00066.2008","article-title":"Diacylglycerol kinase-epsilon restores cardiac dysfunction under chronic pressure overload: a new specific regulator of Galpha(q) signaling cascade","volume":"295","author":"Niizeki","year":"2008","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbrc.2009.12.001_bib22","doi-asserted-by":"crossref","first-page":"7461","DOI":"10.1073\/pnas.102596199","article-title":"Subunit composition of mammalian transient receptor potential channels in living cells","volume":"99","author":"Hofmann","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X09023742?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X09023742?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T10:48:17Z","timestamp":1757760497000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X09023742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["S0006291X09023742"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2009.12.001","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Essential role of TRPC1 channels in cardiomyoblasts hypertrophy mediated by 5-HT2A serotonin receptors","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2009.12.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}