{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:10:00Z","timestamp":1791202200974,"version":"4.2.0"},"reference-count":100,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100001558","name":"Concern Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001558","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000884","name":"Cancer Research Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000884","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Swedish Institute"},{"DOI":"10.13039\/501100001729","name":"Swedish Foundation for Strategic Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001729","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.bbrc.2010.02.146","type":"journal-article","created":{"date-parts":[[2010,5,22]],"date-time":"2010-05-22T04:48:07Z","timestamp":1274503687000},"page":"67-73","source":"Crossref","is-referenced-by-count":75,"title":["Interaction of Epstein-Barr virus (EBV) with human B-lymphocytes"],"prefix":"10.1016","volume":"396","author":[{"given":"George","family":"Klein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Kashuba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2010.02.146_bib1","doi-asserted-by":"crossref","unstructured":"E. Klein, G. Klein (Ed.), Burkitt lymphoma, Semin. Cancer Biol. 19 (6) (2009).","DOI":"10.1016\/j.semcancer.2009.11.002"},{"key":"10.1016\/j.bbrc.2010.02.146_bib2","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/newbio246140a0","article-title":"Human lymphoid cell transformation by Epstein-Barr virus","volume":"246","author":"Pope","year":"1973","journal-title":"Nat. New Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1073\/pnas.59.1.94","article-title":"Relation of Burkitt\u2019s tumor-associated herpes-type virus to infectious mononucleosis","volume":"59","author":"Henle","year":"1968","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib4","doi-asserted-by":"crossref","first-page":"3133","DOI":"10.1016\/j.molimm.2008.03.002","article-title":"EBV transformation overrides gene expression patterns of B cell differentiation stages","volume":"45","author":"Siemer","year":"2008","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib5","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/ijc.2910110302","article-title":"Cellular localization of an Epstein-Barr virus (EBV)-associated complement-fixing antigen in producer and non-producer lymphoblastoid cell lines","volume":"11","author":"Reedman","year":"1973","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2010.02.146_bib6","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/340393a0","article-title":"Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes","volume":"340","author":"Hammerschmidt","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2010.02.146_bib7","doi-asserted-by":"crossref","first-page":"9558","DOI":"10.1073\/pnas.86.23.9558","article-title":"Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation","volume":"86","author":"Cohen","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib8","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1128\/JVI.67.4.2014-2025.1993","article-title":"Epstein-Barr virus nuclear proteins EBNA-3A and EBNA-3C are essential for B-lymphocyte growth transformation","volume":"67","author":"Tomkinson","year":"1993","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib9","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1128\/JVI.69.1.231-238.1995","article-title":"Immortalization of human B lymphocytes by a plasmid containing 71 kilobase pairs of Epstein-Barr virus DNA","volume":"69","author":"Kempkes","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib10","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/j.1460-2075.1995.tb06978.x","article-title":"B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2","volume":"14","author":"Kempkes","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2010.02.146_bib11","doi-asserted-by":"crossref","first-page":"6826","DOI":"10.1128\/JVI.65.12.6826-6837.1991","article-title":"The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation","volume":"65","author":"Mannick","year":"1991","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib12","doi-asserted-by":"crossref","first-page":"9150","DOI":"10.1073\/pnas.90.19.9150","article-title":"Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation","volume":"90","author":"Kaye","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib13","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0092-8674(85)90282-X","article-title":"Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region","volume":"42","author":"Rawlins","year":"1985","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2010.02.146_bib14","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1128\/JVI.63.1.101-110.1989","article-title":"Interaction of the lymphocyte-derived Epstein-Barr virus nuclear antigen EBNA-1 with its DNA-binding sites","volume":"63","author":"Jones","year":"1989","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib15","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.1073\/pnas.81.12.3806","article-title":"A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells","volume":"81","author":"Yates","year":"1984","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib16","doi-asserted-by":"crossref","first-page":"3838","DOI":"10.1128\/MCB.6.11.3838","article-title":"Trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1","volume":"6","author":"Reisman","year":"1986","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib17","doi-asserted-by":"crossref","first-page":"6901","DOI":"10.1128\/MCB.23.19.6901-6908.2003","article-title":"EBNA-1, a bifunctional transcriptional activator","volume":"23","author":"Kennedy","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib18","doi-asserted-by":"crossref","first-page":"14188","DOI":"10.1073\/pnas.0605985103","article-title":"Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV\u2019s transforming genes","volume":"103","author":"Altmann","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib19","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1128\/JVI.73.4.2587-2595.1999","article-title":"EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance","volume":"73","author":"Shire","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib20","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1128\/jvi.76.5.2480-2490.2002","article-title":"Separation of the DNA replication, segregation, and transcriptional activation functions of Epstein-Barr nuclear antigen 1","volume":"76","author":"Wu","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib21","doi-asserted-by":"crossref","first-page":"4934","DOI":"10.1128\/MCB.25.12.4934-4945.2005","article-title":"EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases","volume":"25","author":"Kapoor","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib22","doi-asserted-by":"crossref","first-page":"11487","DOI":"10.1128\/JVI.78.21.11487-11505.2004","article-title":"The amino terminus of Epstein-Barr Virus (EBV) nuclear antigen 1 contains AT hooks that facilitate the replication and partitioning of latent EBV genomes by tethering them to cellular chromosomes","volume":"78","author":"Sears","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib23","doi-asserted-by":"crossref","first-page":"9150","DOI":"10.1128\/JVI.72.11.9150-9156.1998","article-title":"Epstein-Barr virus contributes to the malignant phenotype and to apoptosis resistance in Burkitt\u2019s lymphoma cell line Akata","volume":"72","author":"Komano","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib24","doi-asserted-by":"crossref","first-page":"14269","DOI":"10.1073\/pnas.2336099100","article-title":"Epstein-Barr virus provides a survival factor to Burkitt\u2019s lymphomas","volume":"100","author":"Kennedy","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib25","doi-asserted-by":"crossref","first-page":"29987","DOI":"10.1074\/jbc.M303977200","article-title":"Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP\/USP7","volume":"278","author":"Holowaty","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2010.02.146_bib26","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.1074\/jbc.272.7.3999","article-title":"Epstein-Barr virus nuclear antigen 1 forms a complex with the nuclear transporter karyopherin alpha2","volume":"272","author":"Fischer","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2010.02.146_bib27","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1006\/viro.1999.0054","article-title":"Epstein-Barr virus nuclear antigen-1 binds to nuclear transporter karyopherin alpha1\/NPI-1 in addition to karyopherin alpha2\/Rch1","volume":"266","author":"Ito","year":"2000","journal-title":"Virology"},{"key":"10.1016\/j.bbrc.2010.02.146_bib28","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1006\/viro.1997.8874","article-title":"An imperfect correlation between DNA replication activity of Epstein-Barr virus nuclear antigen 1 (EBNA1) and binding to the nuclear import receptor, Rch1\/importin alpha","volume":"239","author":"Kim","year":"1997","journal-title":"Virology"},{"key":"10.1016\/j.bbrc.2010.02.146_bib29","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1093\/nar\/26.2.631","article-title":"Human RPA (hSSB) interacts with EBNA1, the latent origin binding protein of Epstein-Barr virus","volume":"26","author":"Zhang","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbrc.2010.02.146_bib30","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1128\/JVI.79.3.1559-1568.2005","article-title":"Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migration","volume":"79","author":"Murakami","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib31","doi-asserted-by":"crossref","first-page":"12009","DOI":"10.1128\/JVI.01680-08","article-title":"The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4","volume":"82","author":"Lin","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib32","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1126\/science.8016657","article-title":"Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa","volume":"265","author":"Henkel","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2010.02.146_bib33","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1128\/JVI.69.1.253-262.1995","article-title":"Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1","volume":"69","author":"Johannsen","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib34","doi-asserted-by":"crossref","first-page":"6020","DOI":"10.1128\/JVI.70.9.6020-6028.1996","article-title":"Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF\u2013SWI complex, hSNF5\/Ini1","volume":"70","author":"Wu","year":"1996","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib35","doi-asserted-by":"crossref","first-page":"7568","DOI":"10.1073\/pnas.91.16.7568","article-title":"The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein","volume":"91","author":"Grossman","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib36","doi-asserted-by":"crossref","first-page":"5008","DOI":"10.1128\/JVI.77.8.5008-5013.2003","article-title":"Epstein-Barr virus nuclear antigen 2 binds via its methylated arginine\u2013glycine repeat to the survival motor neuron protein","volume":"77","author":"Barth","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib37","doi-asserted-by":"crossref","first-page":"4735","DOI":"10.1128\/MCB.15.9.4735","article-title":"The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE","volume":"15","author":"Tong","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib38","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1073\/pnas.97.1.430","article-title":"Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter","volume":"97","author":"Wang","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib39","doi-asserted-by":"crossref","first-page":"12694","DOI":"10.1128\/JVI.78.22.12694-12697.2004","article-title":"EBNA2 is required for protection of latently Epstein-Barr virus-infected B cells against specific apoptotic stimuli","volume":"78","author":"Lee","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib40","doi-asserted-by":"crossref","first-page":"3108","DOI":"10.1128\/JVI.69.5.3108-3116.1995","article-title":"Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence-specific DNA-binding protein J kappa","volume":"69","author":"Robertson","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib41","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1006\/viro.1996.0662","article-title":"Epstein-Barr nuclear antigen-3 and -4 interact with RBP-2N, a major isoform of RBP-J kappa in B lymphocytes","volume":"226","author":"Krauer","year":"1996","journal-title":"Virology"},{"key":"10.1016\/j.bbrc.2010.02.146_bib42","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1038\/sj.onc.1207253","article-title":"The EBNA-3 gene family proteins disrupt the G2\/M checkpoint","volume":"23","author":"Krauer","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2010.02.146_bib43","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1038\/sj.onc.1203501","article-title":"Epstein-Barr virus encoded nuclear protein EBNA-3 binds XAP-2, a protein associated with hepatitis B virus X antigen","volume":"19","author":"Kashuba","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2010.02.146_bib44","first-page":"33","article-title":"Epstein-Barr virus-encoded nuclear protein EBNA-3 interacts with the epsilon-subunit of the T-complex protein 1 chaperonin complex","volume":"2","author":"Kashuba","year":"1999","journal-title":"J. Hum. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib45","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1074\/jbc.M509036200","article-title":"Regulation of transactivation function of the aryl hydrocarbon receptor by the Epstein-Barr virus-encoded EBNA-3 protein","volume":"281","author":"Kashuba","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2010.02.146_bib46","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1471-2121-3-23","article-title":"Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase\/uracil phosphoribosyltransferase","volume":"3","author":"Kashuba","year":"2002","journal-title":"BMC Cell Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib47","doi-asserted-by":"crossref","first-page":"8169","DOI":"10.1128\/JVI.69.12.8169-8172.1995","article-title":"The Epstein-Barr virus nuclear antigen leader protein associates with hsp72\/hsc73","volume":"69","author":"Mannick","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib48","doi-asserted-by":"crossref","first-page":"10104","DOI":"10.1128\/JVI.74.21.10104-10111.2000","article-title":"Interaction of Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) with HS1-associated protein X-1: implication of cytoplasmic function of EBNA-LP","volume":"74","author":"Kawaguchi","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib49","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1128\/JVI.75.5.2475-2481.2001","article-title":"EBNA-LP associates with cellular proteins including DNA-PK and HA95","volume":"75","author":"Han","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib50","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1002\/ijc.11124","article-title":"EBV-encoded EBNA-5 associates with P14ARF in extranucleolar inclusions and prolongs the survival of P14ARF-expressing cells","volume":"105","author":"Kashuba","year":"2003","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2010.02.146_bib51","first-page":"47","article-title":"Epstein-Barr virus-encoded EBNA-5 binds to Epstein-Barr virus-induced Fte1\/S3a protein","volume":"303","author":"Kashuba","year":"2005","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.bbrc.2010.02.146_bib52","doi-asserted-by":"crossref","first-page":"19278","DOI":"10.1073\/pnas.0609320103","article-title":"Epstein-Barr nuclear antigen leader protein coactivates transcription through interaction with histone deacetylase 4","volume":"103","author":"Portal","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib53","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1089\/jir.2008.0023","article-title":"Regulation of Sp100A subnuclear localization and transcriptional function by EBNA-LP and interferon","volume":"28","author":"Echendu","year":"2008","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.bbrc.2010.02.146_bib54","doi-asserted-by":"crossref","first-page":"7749","DOI":"10.1128\/JVI.75.16.7749-7755.2001","article-title":"Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C","volume":"75","author":"Touitou","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib55","doi-asserted-by":"crossref","first-page":"5688","DOI":"10.1128\/JVI.73.7.5688-5697.1999","article-title":"Epstein-Barr virus nuclear antigen 3C interacts with histone deacetylase to repress transcription","volume":"73","author":"Radkov","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib56","doi-asserted-by":"crossref","first-page":"4261","DOI":"10.1128\/JVI.77.7.4261-4272.2003","article-title":"Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines","volume":"77","author":"Knight","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib57","doi-asserted-by":"crossref","first-page":"5722","DOI":"10.1128\/MCB.20.15.5722-5735.2000","article-title":"Modulation of histone acetyltransferase activity through interaction of epstein-barr nuclear antigen 3C with prothymosin alpha","volume":"20","author":"Cotter","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib58","doi-asserted-by":"crossref","first-page":"19136","DOI":"10.1074\/jbc.274.27.19136","article-title":"Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C","volume":"274","author":"Grundhoff","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2010.02.146_bib59","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.virol.2003.09.032","article-title":"The Epstein-Barr virus nuclear antigen-6 protein co-localizes with EBNA-3 and survival of motor neurons protein","volume":"318","author":"Krauer","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.bbrc.2010.02.146_bib60","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1128\/JVI.78.4.1981-1991.2004","article-title":"Epstein-Barr virus nuclear antigen 3C regulates cyclin A\/p27 complexes and enhances cyclin A-dependent kinase activity","volume":"78","author":"Knight","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib61","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1128\/MCB.25.5.1749-1763.2005","article-title":"SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen","volume":"25","author":"Knight","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib62","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/85499","article-title":"Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis","volume":"7","author":"Subramanian","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2010.02.146_bib63","doi-asserted-by":"crossref","first-page":"5489","DOI":"10.1073\/pnas.0801053105","article-title":"EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb\u2013E2F1 complexes","volume":"105","author":"Kashuba","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib64","doi-asserted-by":"crossref","first-page":"4652","DOI":"10.1128\/JVI.02408-08","article-title":"Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2","volume":"83","author":"Saha","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib65","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1006\/viro.1994.1578","article-title":"Genetic and biochemical evidence that EBNA 2 interaction with a 63-kDa cellular GTG-binding protein is essential for B lymphocyte growth transformation by EBV","volume":"204","author":"Yalamanchili","year":"1994","journal-title":"Virology"},{"key":"10.1016\/j.bbrc.2010.02.146_bib66","series-title":"Fields Virology","first-page":"2603","article-title":"Epstein-Barr virus and its replication","author":"Kieff","year":"2007"},{"key":"10.1016\/j.bbrc.2010.02.146_bib67","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1002\/j.1460-2075.1994.tb06634.x","article-title":"EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus","volume":"13","author":"Sinclair","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2010.02.146_bib68","doi-asserted-by":"crossref","unstructured":"L.L. Kis, D. Salamon, E.K. Persson, N. Nagy, F.A. Scheeren, H. Spits, G. Klein, E. Klein, IL-21 imposes a type II EBV gene expression on type III and type I B cells by the repression of C- and activation of LMP-1-promoter, Proc. Natl. Acad. Sci. USA 107 (2010) 872\u2013877.","DOI":"10.1073\/pnas.0912920107"},{"key":"10.1016\/j.bbrc.2010.02.146_bib69","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1101\/gad.989602","article-title":"When cell biology meets development: endocytic regulation of signaling pathways","volume":"16","author":"Seto","year":"2002","journal-title":"Genes Dev."},{"issue":"Suppl.","key":"10.1016\/j.bbrc.2010.02.146_bib70","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0092-8674(02)00689-X","article-title":"An invitation to T and more: notch signaling in lymphopoiesis","volume":"109","author":"Allman","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2010.02.146_bib71","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1128\/JVI.73.2.1195-1204.1999","article-title":"Intron retention may regulate expression of Epstein-Barr virus nuclear antigen 3 family genes","volume":"73","author":"Kienzle","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib72","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1128\/JVI.69.6.3624-3630.1995","article-title":"Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator","volume":"69","author":"Marshall","year":"1995","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib73","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1128\/JVI.76.1.232-242.2002","article-title":"Epstein-Barr virus nuclear antigen 3C putative repression domain mediates coactivation of the LMP1 promoter with EBNA-2","volume":"76","author":"Lin","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib74","doi-asserted-by":"crossref","first-page":"4741","DOI":"10.1093\/nar\/24.23.4741","article-title":"XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation","volume":"24","author":"Kuzhandaivelu","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbrc.2010.02.146_bib75","doi-asserted-by":"crossref","first-page":"10437","DOI":"10.1128\/JVI.77.19.10437-10447.2003","article-title":"Epstein-Barr virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth","volume":"77","author":"Maruo","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib76","doi-asserted-by":"crossref","first-page":"e1000506","DOI":"10.1371\/journal.ppat.1000506","article-title":"Differential gene expression patterns of EBV infected EBNA-3A positive and negative human B lymphocytes","volume":"5","author":"Hertle","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2010.02.146_bib77","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/sj.onc.1203327","article-title":"Epstein-Barr virus EBNA3C can disrupt multiple cell cycle checkpoints and induce nuclear division divorced from cytokinesis","volume":"19","author":"Parker","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2010.02.146_bib78","doi-asserted-by":"crossref","first-page":"18562","DOI":"10.1073\/pnas.0503886102","article-title":"Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase","volume":"102","author":"Knight","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib79","doi-asserted-by":"crossref","first-page":"19500","DOI":"10.1073\/pnas.0604919104","article-title":"Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells","volume":"103","author":"Maruo","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib80","doi-asserted-by":"crossref","first-page":"6611","DOI":"10.1128\/JVI.71.9.6611-6618.1997","article-title":"Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation","volume":"71","author":"Harada","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib81","doi-asserted-by":"crossref","first-page":"6619","DOI":"10.1128\/JVI.71.9.6619-6628.1997","article-title":"Epstein-Barr virus leader protein enhances EBNA-2-mediated transactivation of latent membrane protein 1 expression: a role for the W1W2 repeat domain","volume":"71","author":"Nitsche","year":"1997","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib82","doi-asserted-by":"crossref","first-page":"3565","DOI":"10.1038\/sj.emboj.7600820","article-title":"Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100","volume":"24","author":"Ling","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2010.02.146_bib83","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1128\/JVI.70.4.2562-2568.1996","article-title":"The Epstein-Barr virus-encoded nuclear antigen EBNA-5 accumulates in PML-containing bodies","volume":"70","author":"Szekely","year":"1996","journal-title":"J. Virol."},{"issue":"Pt. 10","key":"10.1016\/j.bbrc.2010.02.146_bib84","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1099\/0022-1317-76-10-2423","article-title":"Reversible nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 and hsp70 proteins after exposure to heat shock or cell density congestion","volume":"76","author":"Szekely","year":"1995","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib85","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1099\/0022-1317-82-2-345","article-title":"Proteasome inhibitor induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5","volume":"82","author":"Pokrovskaja","year":"2001","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib86","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1073\/pnas.98.3.1012","article-title":"Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation","volume":"98","author":"Mattsson","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib87","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1476-4598-2-18","article-title":"P14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomes","volume":"2","author":"Kashuba","year":"2003","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bbrc.2010.02.146_bib88","doi-asserted-by":"crossref","first-page":"4994","DOI":"10.1002\/j.1460-2075.1995.tb00182.x","article-title":"DNA damage in human B cells can induce apoptosis, proceeding from G1\/S when p53 is transactivation competent and G2\/M when it is transactivation defective","volume":"14","author":"Allday","year":"1995","journal-title":"EMBO J."},{"issue":"Pt. 4","key":"10.1016\/j.bbrc.2010.02.146_bib89","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1099\/0022-1317-80-4-987","article-title":"Epstein-Barr virus infection and mitogen stimulation of normal B cells induces wild-type p53 without subsequent growth arrest or apoptosis","volume":"80","author":"Pokrovskaja","year":"1999","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib90","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1007\/s00216-006-0867-6","article-title":"SPR-based immunocapture approach to creating an interfacial sensing architecture: mapping of the MRS18-2 binding site on retinoblastoma protein","volume":"386","author":"Snopok","year":"2006","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.bbrc.2010.02.146_bib91","doi-asserted-by":"crossref","first-page":"6577","DOI":"10.1073\/pnas.92.14.6577","article-title":"Persistence of immunoglobulin heavy chain\/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men","volume":"92","author":"Muller","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib92","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0092-8674(92)90123-T","article-title":"Induction of apoptosis in fibroblasts by c-myc protein","volume":"69","author":"Evan","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2010.02.146_bib93","doi-asserted-by":"crossref","first-page":"6069","DOI":"10.1128\/JVI.68.9.6069-6073.1994","article-title":"Isolation of Epstein-Barr virus (EBV)-negative cell clones from the EBV-positive Burkitt\u2019s lymphoma (BL) line Akata: malignant phenotypes of BL cells are dependent on EBV","volume":"68","author":"Shimizu","year":"1994","journal-title":"J. Virol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib94","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/ijc.10498","article-title":"SH2D1A expression in Burkitt lymphoma cells is restricted to EBV positive group I lines and is downregulated in parallel with immunoblastic transformation","volume":"100","author":"Nagy","year":"2002","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2010.02.146_bib95","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S0140-6736(75)92004-8","article-title":"X-linked recessive progressive combined variable immunodeficiency (Duncan\u2019s disease)","volume":"1","author":"Purtilo","year":"1975","journal-title":"Lancet"},{"key":"10.1016\/j.bbrc.2010.02.146_bib96","doi-asserted-by":"crossref","first-page":"13765","DOI":"10.1073\/pnas.95.23.13765","article-title":"Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome","volume":"95","author":"Nichols","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib97","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1038\/26683","article-title":"The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM","volume":"395","author":"Sayos","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2010.02.146_bib98","doi-asserted-by":"crossref","first-page":"11966","DOI":"10.1073\/pnas.0905691106","article-title":"The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease","volume":"106","author":"Nagy","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2010.02.146_bib99","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.semcancer.2009.10.001","article-title":"To the genesis of Burkitt lymphoma: regulation of apoptosis by EBNA-1 and SAP may determine the fate of Ig-myc translocation carrying B lymphocytes","volume":"19","author":"Nagy","year":"2009","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.bbrc.2010.02.146_bib100","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1182\/blood-2005-01-0168","article-title":"Immunoglobulin gene analysis reveals 2 distinct cells of origin for EBV-positive and EBV-negative Burkitt lymphomas","volume":"106","author":"Bellan","year":"2005","journal-title":"Blood"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X10003803?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X10003803?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T19:06:48Z","timestamp":1591297608000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X10003803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":100,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0006291X10003803"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2010.02.146","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}