{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T22:33:14Z","timestamp":1778884394015,"version":"3.51.4"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Special Research Programs","award":["200803015"],"award-info":[{"award-number":["200803015"]}]},{"name":"National Special Research Programs","award":["2009ZX08006-007B"],"award-info":[{"award-number":["2009ZX08006-007B"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.bbrc.2010.04.133","type":"journal-article","created":{"date-parts":[[2010,5,11]],"date-time":"2010-05-11T08:41:03Z","timestamp":1273567263000},"page":"787-792","source":"Crossref","is-referenced-by-count":29,"title":["Design and evaluation of a multi-epitope peptide against Japanese encephalitis virus infection in BALB\/c mice"],"prefix":"10.1016","volume":"396","author":[{"given":"Jian-chao","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-zhu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deng-ke","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Ishag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui-bing","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pu-yan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2010.04.133_bib1","unstructured":"Japanese encephalitis vaccines, Wkly Epidemiol. Rec. 73 (1998) 337\u2013344."},{"key":"10.1016\/j.bbrc.2010.04.133_bib2","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1093\/oxfordjournals.aje.a120643","article-title":"Cyclic outbreaks of Japanese encephalitis among pigs and humans","volume":"2","author":"Konno","year":"1966","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib3","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0889-8561(03)00102-4","article-title":"Allergic reactions to Japanese encephalitis vaccine","volume":"23","author":"Plesner","year":"2003","journal-title":"Immunol. Allergy Clin. North Am."},{"key":"10.1016\/j.bbrc.2010.04.133_bib4","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0169-409X(01)00164-8","article-title":"Nasal delivery of epitope based vaccines","volume":"51","author":"Olszewska","year":"2001","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.bbrc.2010.04.133_bib5","doi-asserted-by":"crossref","first-page":"3606","DOI":"10.4049\/jimmunol.141.10.3606","article-title":"Protection of mice against Japanese encephalitis virus by passive administration with monoclonal antibodies","volume":"141","author":"Kimura-Kuroda","year":"1988","journal-title":"J. Immunol."},{"issue":"Pt. 4","key":"10.1016\/j.bbrc.2010.04.133_bib6","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1099\/0022-1317-77-4-705","article-title":"Protection of adult but not newborn mice against lethal intracerebral challenge with Japanese encephalitis virus by adoptively transferred virus-specific cytotoxic T lymphocytes: requirement for L3T4+ T cells","volume":"77","author":"Murali-Krishna","year":"1996","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/338015","article-title":"Plasmid DNA immunization against Japanese encephalitis virus: immunogenicity of membrane-anchored and secretory envelope protein","volume":"185","author":"Kaur","year":"2002","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.bbrc.2010.04.133_bib8","doi-asserted-by":"crossref","first-page":"5425","DOI":"10.1021\/bi00367a013","article-title":"New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites","volume":"25","author":"Parker","year":"1986","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbrc.2010.04.133_bib9","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1007\/s007050170103","article-title":"Monoclonal antibody raised against envelope glycoprotein peptide neutralizes Japanese encephalitis virus","volume":"146","author":"Dewasthaly","year":"2001","journal-title":"Arch. Virol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1006\/viro.1999.9859","article-title":"Prediction of three-dimensional structure and mapping of conformational epitopes of envelope glycoprotein of Japanese encephalitis virus","volume":"261","author":"Kolaskar","year":"1999","journal-title":"Virology"},{"key":"10.1016\/j.bbrc.2010.04.133_bib11","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/0264-410X(95)00097-K","article-title":"Finer mapping of neutralizing epitope(s) on the C-terminal of Japanese encephalitis virus E-protein expressed in recombinant Escherichia coli system","volume":"13","author":"Seif","year":"1995","journal-title":"Vaccine"},{"key":"10.1016\/j.bbrc.2010.04.133_bib12","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0952-7915(03)00083-9","article-title":"Epitope-based vaccines: an update on epitope identification, vaccine design and delivery","volume":"15","author":"Sette","year":"2003","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1034\/j.1399-0039.2002.590601.x","article-title":"Optimizing vaccine design for cellular processing, MHC binding and TCR recognition","volume":"59","author":"Sette","year":"2002","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.bbrc.2010.04.133_bib14","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1006\/biol.2001.0297","article-title":"The development of multi-epitope vaccines: epitope identification, vaccine design and clinical evaluation","volume":"29","author":"Sette","year":"2001","journal-title":"Biologicals"},{"key":"10.1016\/j.bbrc.2010.04.133_bib15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1574-695X.2000.tb01514.x","article-title":"Candidate multi-epitope vaccines in aluminium adjuvant induce high levels of antibodies with predefined multi-epitope specificity against HIV-1","volume":"29","author":"Ding","year":"2000","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib16","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1016\/S0264-410X(03)00042-2","article-title":"The domain III fragment of Japanese encephalitis virus envelope protein: mouse immunogenicity and liposome adjuvanticity","volume":"21","author":"Wu","year":"2003","journal-title":"Vaccine"},{"key":"10.1016\/j.bbrc.2010.04.133_bib17","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/S0264-410X(01)00416-9","article-title":"Protection induced by intramuscular immunization with DNA vaccines of pseudorabies in mice, rabbits and piglets","volume":"20","author":"Hong","year":"2002","journal-title":"Vaccine"},{"key":"10.1016\/j.bbrc.2010.04.133_bib18","first-page":"11","article-title":"Japanese encephalitis virus: ecology and epidemiology","volume":"267","author":"Endy","year":"2002","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib19","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1586\/14760584.3.2.199","article-title":"Recent advancement in flavivirus vaccine development","volume":"3","author":"Chang","year":"2004","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.bbrc.2010.04.133_bib20","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1365-2222.2005.02234.x","article-title":"Rational design of hypoallergens applied to the major cat allergen Fel d 1","volume":"35","author":"Saarne","year":"2005","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.bbrc.2010.04.133_bib21","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1128\/IAI.00943-07","article-title":"A DNA fusion vaccine induces bactericidal antibodies to a peptide epitope from the PorA porin of Neisseria meningitides","volume":"76","author":"Zhu","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbrc.2010.04.133_bib22","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1016\/j.vaccine.2005.01.059","article-title":"Developing an epitope-driven tuberculosis (TB) vaccine","volume":"23","author":"De Groot","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.bbrc.2010.04.133_bib23","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1080\/13550280390218454","article-title":"Development of a recombinant vaccine against Japanese encephalitis","volume":"9","author":"Kaur","year":"2003","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib24","doi-asserted-by":"crossref","first-page":"4652","DOI":"10.1016\/S0264-410X(01)00233-X","article-title":"Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines","volume":"19","author":"Livingston","year":"2001","journal-title":"Vaccine"},{"key":"10.1016\/j.bbrc.2010.04.133_bib25","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1084\/jem.184.3.863","article-title":"Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells","volume":"184","author":"Cardin","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbrc.2010.04.133_bib26","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/0161-5890(92)90054-2","article-title":"T and B cell responses to chimeric proteins containing heterologous T helper epitopes inserted at different positions","volume":"29","author":"Lowenadler","year":"1992","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib27","doi-asserted-by":"crossref","first-page":"549","DOI":"10.4049\/jimmunol.152.2.549","article-title":"Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs","volume":"152","author":"Shirai","year":"1994","journal-title":"J. Immunol."},{"issue":"Pt. 4","key":"10.1016\/j.bbrc.2010.04.133_bib28","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1099\/0022-1317-75-4-799","article-title":"Cytotoxic T lymphocytes raised against Japanese encephalitis virus: effector cell phenotype, target specificity and in vitro virus clearance","volume":"75","author":"Murali-Krishna","year":"1994","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.bbrc.2010.04.133_bib29","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.vaccine.2008.10.050","article-title":"Evaluation of Japanese encephalitis virus DNA vaccine candidates in rhesus monkeys [Macaca mulatta]","volume":"27","author":"Bharati","year":"2009","journal-title":"Vaccine"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X10008284?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X10008284?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T03:37:34Z","timestamp":1685590654000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X10008284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S0006291X10008284"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2010.04.133","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}