{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T04:34:02Z","timestamp":1721363642287},"reference-count":19,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.bbrc.2011.05.083","type":"journal-article","created":{"date-parts":[[2011,5,22]],"date-time":"2011-05-22T22:36:40Z","timestamp":1306103800000},"page":"752-757","source":"Crossref","is-referenced-by-count":9,"title":["ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK\/mitochondrial pathways"],"prefix":"10.1016","volume":"409","author":[{"given":"Lifang","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Ling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenzhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianxin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2011.05.083_b0100","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1002\/hep.20933","article-title":"Management of hepatocellular carcinoma","volume":"42","author":"Bruix","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.bbrc.2011.05.083_b0010","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1111\/j.1365-2036.2006.02932.x","article-title":"Systematic review: evidence-based management of hepatocellular carcinoma \u2013 an updated analysis of randomized controlled trials","volume":"23","author":"Lopez","year":"2006","journal-title":"Aliment. Pharmacol. Therap."},{"key":"10.1016\/j.bbrc.2011.05.083_b0015","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0165-1110(88)90004-8","article-title":"The ras gene family and human carcinogenesis","volume":"195","author":"Bos","year":"1988","journal-title":"Mutat. Res."},{"key":"10.1016\/j.bbrc.2011.05.083_b0105","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1038\/sj.onc.1202174","article-title":"Increasing complexity of Ras signaling","volume":"17","author":"Campbell","year":"1998","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2011.05.083_b0110","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1158\/0008-5472.CAN-04-0026","article-title":"Galectin-1(L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP","volume":"64","author":"Rotblat","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2011.05.083_b0030","first-page":"235","article-title":"Phase 1 first-in-human clinical study of S-trans, trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors","author":"Tsimberidou","year":"2009","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.bbrc.2011.05.083_b0035","doi-asserted-by":"crossref","first-page":"214","DOI":"10.2174\/156800909787581015","article-title":"Nitric oxide: cancer target or anticancer agent?","volume":"9","author":"Mocellin","year":"2009","journal-title":"Curr. Cancer Drug Targets"},{"key":"10.1016\/j.bbrc.2011.05.083_b0040","first-page":"547","article-title":"Nitric oxide (NO): formation and biological roles in mammalian systems","volume":"36","author":"Fukuto","year":"1999","journal-title":"Met. Ions Biol. Syst."},{"key":"10.1016\/j.bbrc.2011.05.083_b0045","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1021\/jm030544m","article-title":"Design and synthesis of 3\u2032- and 5\u2032-O-(3-benzene-sulfonylfuroxan-4-yl)-2\u2032-deoxyuridines: biological evaluation as hybrid nitric oxide donor-nucleoside anticancer agents","volume":"47","author":"Moharram","year":"2004","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bbrc.2011.05.083_b0050","doi-asserted-by":"crossref","first-page":"3448","DOI":"10.1016\/j.bmc.2010.03.077","article-title":"Synthesis and evaluation of nitric oxide-releasing derivatives of farnesylthiosalicylic acid as anti-tumor agents","volume":"18","author":"Ling","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bbrc.2011.05.083_b0055","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.jep.2010.11.015","article-title":"Taraxacum officinale Weber extracts inhibit LPS-induced oxidative stress and nitric oxide production via the NF-\u03baB modulation in RAW 264.7 cells","volume":"133","author":"Park","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bbrc.2011.05.083_b0060","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1093\/jnci\/djn351","article-title":"Antitumor efficacy testing in rodents","volume":"100","author":"Hollingshead","year":"2008","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.bbrc.2011.05.083_b0065","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1016\/S0093-691X(00)00308-3","article-title":"Assessment of equine sperm mitochondrial function using JC-1","volume":"53","author":"Gravance","year":"2000","journal-title":"Theriogenology"},{"key":"10.1016\/j.bbrc.2011.05.083_b0070","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4103\/0974-2727.54801","article-title":"Apoptotic count as a guide for histological grading of carcinoma esophagus: a light microscopic study","volume":"1","author":"Seth","year":"2009","journal-title":"J. Lab. Physicians"},{"key":"10.1016\/j.bbrc.2011.05.083_b0075","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1016\/j.bcp.2003.12.025","article-title":"Roles of p38 and JNK mitogen-activated protein kinase pathways during cantharidin-induced apoptosis in U937 cells","volume":"67","author":"Huh","year":"2004","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2011.05.083_b0080","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0006-2952(03)00255-7","article-title":"The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide","volume":"66","author":"Brantley-Finley","year":"2003","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2011.05.083_b0085","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1023\/A:1022945107762","article-title":"The mitochondrial membrane potential (\u0394\u03c8m) in apoptosis; an update","volume":"8","author":"Ly","year":"2003","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbrc.2011.05.083_b0090","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1128\/IAI.70.1.55-61.2002","article-title":"Role of Bcl-2 family members in caspase-independent apoptosis during chlamydia infection","volume":"70","author":"Perfettini","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbrc.2011.05.083_b0095","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1038\/sj.cdd.4400781","article-title":"The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability","volume":"7","author":"Harris","year":"2000","journal-title":"Cell Death Differ."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X11008503?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X11008503?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,2]],"date-time":"2018-12-02T15:50:46Z","timestamp":1543765846000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X11008503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0006291X11008503"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2011.05.083","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}