{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:05:23Z","timestamp":1791104723452,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.bbrc.2011.05.113","type":"journal-article","created":{"date-parts":[[2011,5,26]],"date-time":"2011-05-26T05:34:29Z","timestamp":1306388069000},"page":"97-101","source":"Crossref","is-referenced-by-count":64,"title":["Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca2+ uptake in human atrial fibrillation"],"prefix":"10.1016","volume":"410","author":[{"given":"Mayilvahanan","family":"Shanmugam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina E.","family":"Molina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Severac-Bastide","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolphe","family":"Fischmeister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopal J.","family":"Babu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2011.05.113_b0005","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.yjmcc.2007.05.009","article-title":"Differential expression of sarcolipin protein during muscle development and cardiac pathophysiology","volume":"43","author":"Babu","year":"2007","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0010","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1042\/BJ20050068","article-title":"Sarcolipin and phospholamban mRNA and protein expression in cardiac and skeletal muscle of different species","volume":"389","author":"Vangheluwe","year":"2005","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2011.05.113_b0015","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.cardiores.2004.08.012","article-title":"Overexpression of sarcolipin decreases myocyte contractility and calcium transient","volume":"65","author":"Babu","year":"2005","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbrc.2011.05.113_b0020","doi-asserted-by":"crossref","first-page":"3972","DOI":"10.1074\/jbc.M508998200","article-title":"Targeted overexpression of sarcolipin in the mouse heart decreases sarcoplasmic reticulum calcium transport and cardiac contractility","volume":"281","author":"Babu","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2011.05.113_b0025","doi-asserted-by":"crossref","first-page":"9199","DOI":"10.1073\/pnas.0402596101","article-title":"Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice","volume":"101","author":"Asahi","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2011.05.113_b0030","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1073\/pnas.0510883103","article-title":"Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation","volume":"103","author":"Gramolini","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2011.05.113_b0035","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.yjmcc.2009.07.014","article-title":"Threonine-5 at the N-terminus can modulate sarcolipin function in cardiac myocytes","volume":"47","author":"Bhupathy","year":"2009","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0040","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.bbrc.2005.06.186","article-title":"Mechanical stress-dependent transcriptional regulation of sarcolipin gene in the rodent atrium","volume":"334","author":"Shimura","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2011.05.113_b0045","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1365-2362.2004.01422.x","article-title":"Down-regulation of sarcolipin mRNA expression in chronic atrial fibrillation","volume":"34","author":"Uemura","year":"2004","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.bbrc.2011.05.113_b0050","doi-asserted-by":"crossref","first-page":"17867","DOI":"10.1073\/pnas.0707722104","article-title":"Ablation of sarcolipin enhances sarcoplasmic reticulum calcium transport and atrial contractility","volume":"104","author":"Babu","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2011.05.113_b0055","first-page":"S675","article-title":"Loss of Sarcolipin is Associated With Structural and Electrical Remodeling of Atria","volume":"120","author":"Xie","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2011.05.113_b0060","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/cvr\/cvq294","article-title":"Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility","volume":"89","author":"Shanmugam","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbrc.2011.05.113_b0065","doi-asserted-by":"crossref","first-page":"H1669","DOI":"10.1152\/ajpheart.00010.2008","article-title":"Increased intracellular Ca2+ and SR Ca2+ load contribute to arrhythmias after acidosis in rat heart. Role of Ca2+\/calmodulin-dependent protein kinase II","volume":"295","author":"Said","year":"2008","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0070","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1046\/j.1540-8167.2003.02519.x","article-title":"Characterization of sustained atrial tachycardia in dogs with rapid ventricular pacing-induced heart failure","volume":"14","author":"Stambler","year":"2003","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0075","article-title":"Atrial Ca2+ signaling in atrial fibrillation as an antiarrhythmic drug target","author":"Dobrev","year":"2009","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0080","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/FJC.0b013e318171924d","article-title":"Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics","volume":"52","author":"Dobrev","year":"2008","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0085","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.yjmcc.2008.12.004","article-title":"Unique atrial myocyte Ca2+ signaling","volume":"46","author":"Dobrev","year":"2009","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0090","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1161\/CIRCEP.107.754788","article-title":"Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure","volume":"1","author":"Yeh","year":"2008","journal-title":"Circ. Arrhythmias Electrophysiol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0095","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1161\/01.RES.81.4.512","article-title":"Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation","volume":"81","author":"Yue","year":"1997","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbrc.2011.05.113_b0100","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1161\/01.CIR.98.7.719","article-title":"Cellular mechanisms of atrial contractile dysfunction caused by sustained atrial tachycardia","volume":"98","author":"Sun","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2011.05.113_b0105","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1046\/j.1540-8167.2003.03110.x","article-title":"Focal origin of atrial tachycardia in dogs with rapid ventricular pacing-induced heart failure","volume":"14","author":"Fenelon","year":"2003","journal-title":"J. Cardiovasc. Electrophysiol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0110","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1161\/CIRCRESAHA.107.153858","article-title":"Spatial distribution of fibrosis governs fibrillation wave dynamics in the posterior left atrium during heart failure","volume":"101","author":"Tanaka","year":"2007","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbrc.2011.05.113_b0115","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1161\/01.CIR.92.7.1954","article-title":"Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats","volume":"92","author":"Wijffels","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2011.05.113_b0120","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.tcm.2010.03.004","article-title":"Calmodulin kinase II, sarcoplasmic reticulum Ca2+ leak, and atrial fibrillation","volume":"20","author":"Dobrev","year":"2010","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.bbrc.2011.05.113_b0125","doi-asserted-by":"crossref","unstructured":"A. Llach, C.E. Molina, J. Fernandes, J. Padro, J. Cinca, L. Hove-Madsen, Sarcoplasmic reticulum and L-type Ca2+ channel activity regulate the beat-to-beat stability of calcium handling in human atrial myocytes, J Physiol. (2011). PMID:21521767 [Epub ahead of print].","DOI":"10.1113\/jphysiol.2010.197715"},{"key":"10.1016\/j.bbrc.2011.05.113_b0130","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1139\/y06-023","article-title":"Regulation of the sarcoplasmic reticulum Ca2+-ATPase expression in the hypertrophic and failing heart","volume":"84","author":"Zarain-Herzberg","year":"2006","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.bbrc.2011.05.113_b0135","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/mus.20745","article-title":"SERCA pump isoforms: their role in calcium transport and disease","volume":"35","author":"Periasamy","year":"2007","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.bbrc.2011.05.113_b0140","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1161\/CIRCULATIONAHA.107.748053","article-title":"Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences","volume":"117","author":"Burstein","year":"2008","journal-title":"Circulation"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X11008886?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X11008886?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T05:58:13Z","timestamp":1560232693000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X11008886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0006291X11008886"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2011.05.113","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}