{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:59:28Z","timestamp":1760853568630,"version":"3.44.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1016\/j.bbrc.2011.06.173","type":"journal-article","created":{"date-parts":[[2011,7,5]],"date-time":"2011-07-05T12:09:08Z","timestamp":1309867748000},"page":"433-439","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Structural and mutational analyses of the receptor binding domain of botulinum D\/C mosaic neurotoxin: Insight into the ganglioside binding mechanism"],"prefix":"10.1016","volume":"411","author":[{"given":"Nipawan","family":"Nuemket","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikazu","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Tsukamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Tsuji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunji","family":"Kozaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isao","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2011.06.173_b0005","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.vetmic.2009.07.023","article-title":"Characterization of the D\/C mosaic neurotoxin produced by Clostridium botulinum associated with bovine botulism in Japan","volume":"140","author":"Nakamura","year":"2010","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.bbrc.2011.06.173_b0010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0167-4781(96)00006-1","article-title":"Mosaic structures of neurotoxins produced from Clostridium botulinum types C and D organisms","volume":"1307","author":"Moriishi","year":"1996","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbrc.2011.06.173_b0015","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1038\/2338","article-title":"Crystal structure of botulinum neurotoxin type A and implications for toxicity","volume":"5","author":"Lacy","year":"1998","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.bbrc.2011.06.173_b0020","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/78005","article-title":"Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B","volume":"7","author":"Swaminathan","year":"2000","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.bbrc.2011.06.173_b0025","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1006\/jmbi.1999.2945","article-title":"Sequence homology and structural analysis of the clostridial neurotoxins","volume":"291","author":"Lacy","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.06.173_b0030","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1111\/j.1471-4159.2009.06298.x","article-title":"Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor","volume":"110","author":"Rummel","year":"2009","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbrc.2011.06.173_b0035","doi-asserted-by":"crossref","first-page":"30865","DOI":"10.1074\/jbc.M403945200","article-title":"Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G","volume":"279","author":"Rummel","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2011.06.173_b0040","doi-asserted-by":"crossref","first-page":"6019","DOI":"10.1021\/ac000846l","article-title":"Gangliosides as receptors for biological toxins: development of sensitive fluoroimmunoassays using ganglioside-bearing liposomes","volume":"72","author":"Singh","year":"2000","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bbrc.2011.06.173_b0045","doi-asserted-by":"crossref","first-page":"e1000129","DOI":"10.1371\/journal.ppat.1000129","article-title":"Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin\u2013neuron interaction","volume":"4","author":"Stenmark","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2011.06.173_b0050","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1038\/nature05387","article-title":"Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity","volume":"444","author":"Jin","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2011.06.173_b0055","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1042\/BJ20101042","article-title":"Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner","volume":"431","author":"Strotmeier","year":"2010","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2011.06.173_b0060","doi-asserted-by":"crossref","first-page":"8117","DOI":"10.1021\/bi100865f","article-title":"Identification of a unique ganglioside binding loop within botulinum neurotoxins C and D-SA","volume":"49","author":"Karalewitz","year":"2010","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbrc.2011.06.173_b0065","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1107\/S1744309110012182","article-title":"Preliminary X-ray crystallographic study of the receptor-binding domain of the D\/C mosaic neurotoxin from Clostridium botulinum","volume":"66","author":"Nuemket","year":"2010","journal-title":"Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun."},{"key":"10.1016\/j.bbrc.2011.06.173_b0070","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0076-6879(97)76066-X","article-title":"Processing of X-ray diffraction data collected in oscillation mode","volume":"276","author":"Otwinowski","year":"1997","journal-title":"Method. Enzymol."},{"key":"10.1016\/j.bbrc.2011.06.173_b0075","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1107\/S0907444909047337","article-title":"XDS","volume":"66","author":"Kabsch","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bbrc.2011.06.173_b0080","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1107\/S0907444909042589","article-title":"Molecular replacement with MOLREP","volume":"66","author":"Vagin","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bbrc.2011.06.173_b0085","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1107\/S0907444994003112","article-title":"The CCP4 suite: programs for protein crystallography","volume":"50","author":"N. Collaborative Computational Project","year":"1994","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bbrc.2011.06.173_b0090","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1107\/S0907444904019158","article-title":"Coot: model-building tools for molecular graphics","volume":"60","author":"Emsley","year":"2004","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bbrc.2011.06.173_b0095","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1107\/S0907444911001314","article-title":"REFMAC5 for the refinement of macromolecular crystal structures","volume":"67","author":"Murshudov","year":"2011","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bbrc.2011.06.173_b0100","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1107\/S0907444902016657","article-title":"PHENIX: building new software for automated crystallographic structure determination","volume":"58","author":"Adams","year":"2002","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bbrc.2011.06.173_b0105","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/978-1-60327-058-8_28","article-title":"Automated structure solution with the PHENIX suite","volume":"426","author":"Zwart","year":"2008","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.06.173_b0110","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/299165a0","article-title":"Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line","volume":"299","author":"McBurney","year":"1982","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2011.06.173_b0115","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1523\/JNEUROSCI.08-03-01063.1988","article-title":"Differentiation and maturation of embryonal carcinoma-derived neurons in cell culture","volume":"8","author":"McBurney","year":"1988","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2011.06.173_b0120","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.bbrc.2010.11.134","article-title":"Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions","volume":"404","author":"Zhang","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2011.06.173_b0125","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/nature05411","article-title":"Structural basis of cell surface receptor recognition by botulinum neurotoxin B","volume":"444","author":"Chai","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2011.06.173_b0130","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jmb.2008.12.027","article-title":"Domain organization in Clostridium botulinum neurotoxin type E is unique: its implication in faster translocation","volume":"386","author":"Kumaran","year":"2009","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.06.173_b0135","doi-asserted-by":"crossref","first-page":"26569","DOI":"10.1074\/jbc.M109.027391","article-title":"Gangliosides as high affinity receptors for tetanus neurotoxin","volume":"284","author":"Chen","year":"2009","journal-title":"J. Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X11011867?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X11011867?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T10:55:57Z","timestamp":1757760957000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X11011867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S0006291X11011867"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2011.06.173","relation":{},"ISSN":["0006-291X"],"issn-type":[{"type":"print","value":"0006-291X"}],"subject":[],"published":{"date-parts":[[2011,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural and mutational analyses of the receptor binding domain of botulinum D\/C mosaic neurotoxin: Insight into the ganglioside binding mechanism","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2011.06.173","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}