{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T12:35:11Z","timestamp":1717158911063},"reference-count":40,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Next-Generation BioGreen 21 Program","award":["PJ008158"],"award-info":[{"award-number":["PJ008158"]}]},{"DOI":"10.13039\/501100003627","name":"Rural Development Administration","doi-asserted-by":"crossref","award":["NRF-C1ABA001-2011-0018559"],"award-info":[{"award-number":["NRF-C1ABA001-2011-0018559"]}],"id":[{"id":"10.13039\/501100003627","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["M103KV010005-06K2201-00610"],"award-info":[{"award-number":["M103KV010005-06K2201-00610"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Brain Research Center"},{"name":"BioImaging Research Center"},{"DOI":"10.13039\/501100002582","name":"Gwangju Institute of Science and Technology","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002582","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.bbrc.2011.11.003","type":"journal-article","created":{"date-parts":[[2011,11,10]],"date-time":"2011-11-10T23:03:02Z","timestamp":1320966182000},"page":"277-282","source":"Crossref","is-referenced-by-count":5,"title":["Expression and characterization of recombinant kurtoxin, an inhibitor of T-type voltage-gated calcium channels"],"prefix":"10.1016","volume":"416","author":[{"given":"Chul Won","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Jae","family":"Eu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Jung","family":"Min","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-Mi","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ha Hyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Yeol","family":"Nah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenton J.","family":"Swartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Il","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2011.11.003_b0005","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0165-6147(91)90595-J","article-title":"Molecular diversity of voltage-dependent Ca2+ channels","volume":"12","author":"Tsien","year":"1991","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bbrc.2011.11.003_b0010","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0896-6273(00)81057-0","article-title":"Nomenclature of voltage-gated calcium channels","volume":"25","author":"Ertel","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2011.11.003_b0015","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0021-9258(18)45955-8","article-title":"Voltage-sensitive Ca2+ channels","volume":"267","author":"Miller","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2011.11.003_b0020","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1523\/JNEUROSCI.15-04-02995.1995","article-title":"Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neurons","volume":"15","author":"Randall","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2011.11.003_b0025","doi-asserted-by":"crossref","first-page":"8748","DOI":"10.1021\/bi9602674","article-title":"A novel hydrophobic omega-conotoxin blocks molluscan dihydropyridine-sensitive calcium channels","volume":"35","author":"Fainzilber","year":"1996","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbrc.2011.11.003_b0030","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1146\/annurev.bi.63.070194.004135","article-title":"Calcium channel diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins","volume":"63","author":"Olivera","year":"1994","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbrc.2011.11.003_b0035","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/310501a0","article-title":"A low voltage-activated, fully inactivating Ca channel in vertebrate sensory neurones","volume":"310","author":"Carbone","year":"1984","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2011.11.003_b0040","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1085\/jgp.96.3.603","article-title":"Mechanism of gating of T-type calcium channels","volume":"96","author":"Chen","year":"1990","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0045","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.tips.2008.10.004","article-title":"Regulation of neuronal T-type calcium channels","volume":"30","author":"Iftinca","year":"2009","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bbrc.2011.11.003_b0050","first-page":"105","article-title":"Pharmacology of recombinant low-voltage activated calcium channels","volume":"3","author":"Lacinova","year":"2004","journal-title":"Curr. Drug Targets: CNS Neurol. Disord."},{"key":"10.1016\/j.bbrc.2011.11.003_b0055","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/8070","article-title":"Splicing of alpha 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels","volume":"2","author":"Bourinet","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2011.11.003_b0060","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1016\/S0006-3495(99)77300-5","article-title":"Structural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels","volume":"76","author":"Hans","year":"1999","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbrc.2011.11.003_b0065","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1085\/jgp.20028560","article-title":"Interactions among toxins that inhibit N-type and P-type calcium channels","volume":"119","author":"McDonough","year":"2002","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0070","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1016\/S0006-3495(97)78854-4","article-title":"Alteration of P-type calcium channel gating by the spider toxin omega-Aga-IVA","volume":"72","author":"McDonough","year":"1997","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbrc.2011.11.003_b0075","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/355827a0","article-title":"P-type calcium channels blocked by the spider toxin omega-Aga-IVA","volume":"355","author":"Mintz","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2011.11.003_b0080","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1085\/jgp.116.5.637","article-title":"A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels","volume":"116","author":"Winterfield","year":"2000","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0085","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1038\/3669","article-title":"Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin","volume":"1","author":"Chuang","year":"1998","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2011.11.003_b0090","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00210-008-0385-5","article-title":"Actions of kurtoxin on tetrodotoxin-sensitive voltage-gated Na+ currents, Na V1.6, in murine vas deferens myocytes","volume":"379","author":"Zhu","year":"2009","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0095","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0076-6879(67)11029-X","article-title":"The cyanogen bromide reaction","volume":"11","author":"Gross","year":"1967","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0100","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/0003-2697(87)90135-7","article-title":"Variable selection method improves the prediction of protein secondary structure from circular dichroism spectra","volume":"167","author":"Manavalan","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbrc.2011.11.003_b0105","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1006\/abio.1993.1079","article-title":"A self-consistent method for the analysis of protein secondary structure from circular dichroism","volume":"209","author":"Sreerama","year":"1993","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbrc.2011.11.003_b0110","doi-asserted-by":"crossref","first-page":"10022","DOI":"10.1021\/bi00199a028","article-title":"Poly(pro)II helices in globular proteins: identification and circular dichroic analysis","volume":"33","author":"Sreerama","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbrc.2011.11.003_b0115","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/protein\/6.4.383","article-title":"Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network","volume":"6","author":"Andrade","year":"1993","journal-title":"Protein Eng."},{"key":"10.1016\/j.bbrc.2011.11.003_b0120","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1006\/jmbi.1999.3036","article-title":"Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel","volume":"292","author":"He","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0125","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1006\/jmbi.1994.1270","article-title":"Crystal structure of toxin II from the scorpion Androctonus australis Hector refined at 1.3A resolution","volume":"238","author":"Housset","year":"1994","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0130","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0022-2836(95)80062-X","article-title":"Solution structure of an old world-like neurotoxin from the venom of the New World scorpion Centruroides sculpturatus Ewing","volume":"248","author":"Jablonsky","year":"1995","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0205","series-title":"Bioorganic Chemistry: Peptides and Proteins","author":"Hecht","year":"1998"},{"key":"10.1016\/j.bbrc.2011.11.003_b0140","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/BF02442592","article-title":"Chemical synthesis of kurtoxin, a T-type calcium channel blocker","volume":"10","author":"Nishio","year":"2003","journal-title":"Lett. Pept. Sci."},{"key":"10.1016\/j.bbrc.2011.11.003_b0145","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1006\/jmbi.1998.2418","article-title":"NMR structures and activity of a novel alpha-like toxin from the scorpion Leiurus quinquestriatus hebraeus","volume":"285","author":"Krimm","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0150","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/(SICI)1097-0134(199707)28:3<360::AID-PROT6>3.0.CO;2-G","article-title":"Refined solution structure of the anti-mammal and anti-insect LqqIII scorpion toxin: comparison with other scorpion toxins","volume":"28","author":"Landon","year":"1997","journal-title":"Proteins"},{"key":"10.1016\/j.bbrc.2011.11.003_b0155","doi-asserted-by":"crossref","first-page":"24125","DOI":"10.1074\/jbc.M211931200","article-title":"Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited","volume":"278","author":"Sun","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2011.11.003_b0160","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1021\/bi0353373","article-title":"Solution structure and functional characterization of SGTx1, a modifier of Kv2.1 channel gating","volume":"43","author":"Lee","year":"2004","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbrc.2011.11.003_b0165","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1006\/jmbi.2000.3609","article-title":"Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins","volume":"297","author":"Takahashi","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0170","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0022-2836(02)00595-8","article-title":"Solution structure of omega-grammotoxin SIA, a gating modifier of P\/Q and N-type Ca(2+) channel","volume":"321","author":"Takeuchi","year":"2002","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2011.11.003_b0175","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/nature01580","article-title":"X-ray structure of a voltage-dependent K+ channel","volume":"423","author":"Jiang","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2011.11.003_b0180","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/nature01581","article-title":"The principle of gating charge movement in a voltage-dependent K+ channel","volume":"423","author":"Jiang","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2011.11.003_b0185","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0896-6273(00)80307-4","article-title":"Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels","volume":"18","author":"Swartz","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2011.11.003_b0190","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0896-6273(00)80306-2","article-title":"Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites","volume":"18","author":"Swartz","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2011.11.003_b0195","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.toxicon.2006.09.024","article-title":"Tarantula toxins interacting with voltage sensors in potassium channels","volume":"49","author":"Swartz","year":"2007","journal-title":"Toxicon"},{"key":"10.1016\/j.bbrc.2011.11.003_b0200","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1523\/JNEUROSCI.22-06-02023.2002","article-title":"Kurtoxin, a gating modifier of neuronal high- and low-threshold ca channels","volume":"22","author":"Sidach","year":"2002","journal-title":"J. Neurosci."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X1102002X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X1102002X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T02:13:46Z","timestamp":1639620826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X1102002X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":40,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0006291X1102002X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2011.11.003","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]}}}