{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T12:22:22Z","timestamp":1775478142581,"version":"3.50.1"},"reference-count":34,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People\u2019s Republic of China","doi-asserted-by":"crossref","award":["2012ZX10004213-004"],"award-info":[{"award-number":["2012ZX10004213-004"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Guangdong Provincial Science Fund for Outstanding Scientists 2011 and National Natural Science Foundation of China","award":["81173616"],"award-info":[{"award-number":["81173616"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.bbrc.2012.11.101","type":"journal-article","created":{"date-parts":[[2012,12,5]],"date-time":"2012-12-05T15:49:00Z","timestamp":1354722540000},"page":"629-633","source":"Crossref","is-referenced-by-count":64,"title":["lncRNA expression signatures in response to enterovirus 71 infection"],"prefix":"10.1016","volume":"430","author":[{"given":"Zhixin","family":"Yin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawei","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenling","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenli","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changwen","family":"Ke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2012.11.101_b0005","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1743-422X-4-70","article-title":"Epidemics to eradication: the modern history of poliomyelitis","volume":"4","author":"De Jesus","year":"2007","journal-title":"Virol. J."},{"key":"10.1016\/j.bbrc.2012.11.101_b0010","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1086\/592988","article-title":"Enterovirus-associated encephalitis in the California encephalitis project 1998-2005","volume":"198","author":"Fowlkes","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.bbrc.2012.11.101_b0015","doi-asserted-by":"crossref","first-page":"828","DOI":"10.3201\/eid1405.071121","article-title":"Acute encephalitis caused by intrafamilial transmission of enterovirus 71 in adult","volume":"14","author":"Hamaguchi","year":"2008","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.bbrc.2012.11.101_b0020","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1574-6976.2002.tb00601.x","article-title":"An overview of the evolution of enterovirus 71 and its clinical and public health significance","volume":"26","author":"McMinn","year":"2002","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.bbrc.2012.11.101_b0025","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.virusres.2009.06.006","article-title":"Appearance of mosaic enterovirus 71 in the 2008 outbreak of China","volume":"145","author":"Ding","year":"2009","journal-title":"Virus Res."},{"key":"10.1016\/j.bbrc.2012.11.101_b0030","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3109\/1040841X.2011.580723","article-title":"The virology and developments toward control of human enterovirus 71","volume":"37","author":"Yi","year":"2011","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.bbrc.2012.11.101_b0035","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1017\/S0950268809991555","article-title":"Human enterovirus 71 and hand foot and mouth disease","volume":"138","author":"Wong","year":"2010","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.bbrc.2012.11.101_b0040","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1086\/319255","article-title":"Altered cellular but not humoral reactions in children with complicated enterovirus 71 infections in Taiwan","volume":"183","author":"Yang","year":"2001","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.bbrc.2012.11.101_b0045","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1203\/01.pdr.0000238247.86041.19","article-title":"Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71","volume":"60","author":"Chang","year":"2006","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.bbrc.2012.11.101_b0050","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1080\/13550280490499551","article-title":"Identification of genes involved in the host response to enterovirus 71 infection","volume":"10","author":"Shih","year":"2004","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.bbrc.2012.11.101_b0055","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1462-5822.2005.00644.x","article-title":"Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection","volume":"8","author":"Leong","year":"2006","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.bbrc.2012.11.101_b0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2010\/365318","article-title":"Identification of microRNAs involved in the host response to enterovirus 71 infection by a deep sequencing approach","volume":"2010","author":"Cui","year":"2010","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.bbrc.2012.11.101_b0065","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1038\/nrg2521","article-title":"Long non-coding RNAs: insights into functions","volume":"10","author":"Mercer","year":"2009","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.bbrc.2012.11.101_b0070","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.molcel.2011.08.018","article-title":"Molecular mechanisms of long noncoding RNAs","volume":"43","author":"Wang","year":"2011","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbrc.2012.11.101_b0075","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.cell.2011.03.014","article-title":"No-nonsense functions for long noncoding RNAs","volume":"145","author":"Nagano","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2012.11.101_b0080","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.semcdb.2011.01.001","article-title":"Long noncoding RNAs in cell biology","volume":"22","author":"Clark","year":"2011","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.bbrc.2012.11.101_b0085","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/bies.080099","article-title":"RNA regulation of epigenetic processes","volume":"31","author":"Mattick","year":"2009","journal-title":"BioEssays"},{"key":"10.1016\/j.bbrc.2012.11.101_b0090","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00251-008-0337-8","article-title":"Non-coding RNAs revealed during identification of genes involved in chicken immune responses","volume":"61","author":"Ahanda","year":"2009","journal-title":"Immunogenetics"},{"key":"10.1016\/j.bbrc.2012.11.101_b0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/mBio.00206-10","article-title":"Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling","volume":"1","author":"Peng","year":"2010","journal-title":"MBio"},{"key":"10.1016\/j.bbrc.2012.11.101_b0100","first-page":"316","article-title":"The complete sequence analyses of Enterovirus 71 strain from the fatal case of the hand, foot and mouth disease during an epidemic in GuangDong, 2008","volume":"29","author":"Zhang","year":"2009","journal-title":"Chin. J. Microbiol. Immunol."},{"issue":"Suppl. 1","key":"10.1016\/j.bbrc.2012.11.101_b0175","volume":"7","author":"Harrow","year":"2006","journal-title":"Genome Biol."},{"key":"10.1016\/j.bbrc.2012.11.101_b0110","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.cell.2010.09.001","article-title":"Long noncoding RNAs with enhancer-like function in human cells","volume":"143","author":"Orom","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2012.11.101_b0115","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nature07672","article-title":"Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals","volume":"458","author":"Guttman","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2012.11.101_b0120","doi-asserted-by":"crossref","first-page":"11667","DOI":"10.1073\/pnas.0904715106","article-title":"Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression","volume":"106","author":"Khalil","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2012.11.101_b0125","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.cell.2007.05.022","article-title":"Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs","volume":"129","author":"Rinn","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2012.11.101_b0130","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative C(T) method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbrc.2012.11.101_b0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000617","article-title":"Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain","volume":"5","author":"Ponjavic","year":"2009","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bbrc.2012.11.101_b0140","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang da","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbrc.2012.11.101_b0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/gkn923","article-title":"Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists","volume":"37","author":"Huang da","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbrc.2012.11.101_b0150","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1093\/nar\/gkn1004","article-title":"Cellular versus viral microRNAs in host-virus interaction","volume":"37","author":"Ghosh","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbrc.2012.11.101_b0155","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1101\/gad.1416106","article-title":"The Evf-2 noncoding RNA is transcribed from the Dlx-5\/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator","volume":"20","author":"Feng","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbrc.2012.11.101_b0160","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/nature04518","article-title":"RNA-mediated response to heat shock in mammalian cells","volume":"440","author":"Shamovsky","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2012.11.101_b0165","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0092-8674(00)80711-4","article-title":"A steroid receptor functions coactivator SRAas an RNA and is present in an SRC-1 complex","volume":"97","author":"Lanz","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2012.11.101_b0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027071","article-title":"Serum microRNA expression profile distinguishes enterovirus 71 and coxsackievirus 16 infections in patients with hand-foot-and-mouth disease","volume":"6","author":"Cui","year":"2011","journal-title":"PLoS ONE"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X12022917?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X12022917?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,6]],"date-time":"2019-07-06T16:42:01Z","timestamp":1562431321000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X12022917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0006291X12022917"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2012.11.101","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}