{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:36:44Z","timestamp":1761597404142},"reference-count":14,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31171042","3127148"],"award-info":[{"award-number":["31171042","3127148"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.bbrc.2013.01.097","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T17:13:46Z","timestamp":1360084426000},"page":"355-358","source":"Crossref","is-referenced-by-count":14,"title":["Doxycycline can stimulate cytoprotection in neural stem cells with oxygen\u2013glucose deprivation\u2013reoxygenation injury: A potential approach to enhance effectiveness of cell transplantation therapy"],"prefix":"10.1016","volume":"432","author":[{"given":"Yousra Saeed","family":"Malik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Abid","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojuan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2013.01.097_b0005","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1161\/01.STR.0000247888.25985.62","article-title":"Cell transplantation therapy for stroke","volume":"38","author":"Bliss","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.bbrc.2013.01.097_b0010","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/ageing\/afq133","article-title":"Human stem cell therapy in ischaemic stroke: a review","volume":"40","author":"Banerjee","year":"2011","journal-title":"Age Ageing"},{"key":"10.1016\/j.bbrc.2013.01.097_b0015","doi-asserted-by":"crossref","first-page":"e9767","DOI":"10.1371\/journal.pone.0009767","article-title":"Murine neural stem\/progenitor cells protect neurons against ischemia by HIF-1alpha-regulated VEGF signaling","volume":"5","author":"Harms","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2013.01.097_b0020","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1111\/j.1460-9568.2008.06599.x","article-title":"Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional recovery","volume":"29","author":"Hicks","year":"2009","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbrc.2013.01.097_b0025","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nrn1106","article-title":"Mechanisms, challenges and opportunities in stroke","volume":"4","author":"Lo","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbrc.2013.01.097_b0030","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.nbd.2004.12.016","article-title":"Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia","volume":"19","author":"Wei","year":"2005","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbrc.2013.01.097_b0035","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1093\/brain\/awl207","article-title":"Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia","volume":"129","author":"Liu","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.bbrc.2013.01.097_b0040","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/sj.jcbfm.9600025","article-title":"Doxycycline reduces cleaved caspase-3 and microglial activation in an animal model of neonatal hypoxia-ischemia","volume":"25","author":"Jantzie","year":"2005","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.bbrc.2013.01.097_b0045","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s12031-011-9689-x","article-title":"Doxycycline-mediated protective effect against focal cerebral ischemia-reperfusion injury through the modulation of tight junctions and PKCdelta signaling in rats","volume":"47","author":"Wang","year":"2012","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.bbrc.2013.01.097_b0050","doi-asserted-by":"crossref","first-page":"15769","DOI":"10.1073\/pnas.95.26.15769","article-title":"Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia","volume":"95","author":"Yrjanheikki","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2013.01.097_b0055","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.tips.2004.10.001","article-title":"Neuroprotection by tetracyclines","volume":"25","author":"Domercq","year":"2004","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bbrc.2013.01.097_b0060","first-page":"1407","article-title":"Doxycycline and minocycline for the management of acne: a review of efficacy and safety with emphasis on clinical implications","volume":"9","author":"Kircik","year":"2010","journal-title":"J. Drugs Dermatol."},{"key":"10.1016\/j.bbrc.2013.01.097_b0065","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1089\/ars.2010.3576","article-title":"Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection","volume":"14","author":"Chen","year":"2011","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbrc.2013.01.097_b0070","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/j.freeradbiomed.2009.07.035","article-title":"Nrf2:INrf2 (Keap1) signaling in oxidative stress","volume":"47","author":"Kaspar","year":"2009","journal-title":"Free Radic. Biol. Med."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X13001873?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X13001873?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T00:25:22Z","timestamp":1539908722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X13001873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S0006291X13001873"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2013.01.097","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}