{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:33:30Z","timestamp":1791160410833,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100007391","name":"the \u201cAssociation pour la Recherche sur le Cancer\u201d (ARC)","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007391","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004099","name":"the \u201cLigue Nationale Contre le Cancer\u201d","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004099","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Comit\u00e9 du Pas de Calais"},{"name":"the Thomas Family Foundation"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.bbrc.2013.09.091","type":"journal-article","created":{"date-parts":[[2013,9,25]],"date-time":"2013-09-25T02:03:09Z","timestamp":1380074589000},"page":"424-430","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Reelin receptors ApoER2 and VLDLR are direct target genes of HIC1 (Hypermethylated In Cancer 1)"],"prefix":"10.1016","volume":"440","author":[{"given":"Marion","family":"Dubuissez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perrine","family":"Faiderbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Pinte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Dehennaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian R.","family":"Rood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Leprince","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2013.09.091_b0005","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/nrn2009","article-title":"Reelin, lipoprotein receptors and synaptic plasticity","volume":"7","author":"Herz","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbrc.2013.09.091_b0010","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1111\/j.1460-9568.2010.07222.x","article-title":"Emerging topics in Reelin function","volume":"31","author":"Forster","year":"2010","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbrc.2013.09.091_b0015","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1750-1326-6-30","article-title":"Similarities and differences in structure, expression, and functions of VLDLR and ApoER2","volume":"6","author":"Reddy","year":"2011","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.bbrc.2013.09.091_b0020","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1146\/annurev.neuro.24.1.1005","article-title":"Role of the Reelin signaling pathway in central nervous system development","volume":"24","author":"Rice","year":"2001","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.bbrc.2013.09.091_b0025","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s00018-012-1171-6","article-title":"Reelin-disabled-1 signaling in neuronal migration: splicing takes the stage","volume":"70","author":"Gao","year":"2013","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbrc.2013.09.091_b0030","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1242\/dev.057588","article-title":"Disruption of Reelin signaling alters mammary gland morphogenesis","volume":"138","author":"Khialeeva","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.bbrc.2013.09.091_b0035","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.2353\/ajpath.2010.100209","article-title":"Loss of Reelin expression in breast cancer is epigenetically controlled and associated with poor prognosis","volume":"177","author":"Stein","year":"2010","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbrc.2013.09.091_b0040","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.3748\/wjg.v11.i18.2817","article-title":"Variations of very low-density lipoprotein receptor subtype expression in gastrointestinal adenocarcinoma cells with various differentiations","volume":"11","author":"Chen","year":"2005","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.bbrc.2013.09.091_b0045","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1186\/1471-2407-10-601","article-title":"Up-regulated expression of type II very low density lipoprotein receptor correlates with cancer metastasis and has a potential link to beta-catenin in different cancers","volume":"10","author":"He","year":"2010","journal-title":"BMC Cancer"},{"key":"10.1016\/j.bbrc.2013.09.091_b0050","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3892\/ijo.2012.1488","article-title":"Reelin signalling in neuroblastoma: migratory switch in metastatic stages","volume":"41","author":"Becker","year":"2012","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.bbrc.2013.09.091_b0055","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/nm0695-570","article-title":"P53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3","volume":"1","author":"Wales","year":"1995","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2013.09.091_b0060","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1517\/14728222.2013.788152","article-title":"Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics","volume":"17","author":"Rood","year":"2013","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.bbrc.2013.09.091_b0065","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/ng1077","article-title":"Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors","volume":"33","author":"Chen","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbrc.2013.09.091_b0070","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/hmg\/9.3.413","article-title":"Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller\u2013Dieker syndrome","volume":"9","author":"Carter","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbrc.2013.09.091_b0075","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1086\/378096","article-title":"Miller\u2013Dieker syndrome: analysis of a human contiguous gene syndrome in the mouse","volume":"73","author":"Yingling","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbrc.2013.09.091_b0080","doi-asserted-by":"crossref","first-page":"20927","DOI":"10.1074\/jbc.M109.022350","article-title":"Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (Hypermethylated In Cancer 1)","volume":"284","author":"Van Rechem","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2013.09.091_b0085","doi-asserted-by":"crossref","first-page":"5379","DOI":"10.1074\/jbc.M111.304287","article-title":"Loss of hypermethylated in cancer 1 (HIC1) in breast cancer cells contributes to stress-induced migration and invasion through beta-2 adrenergic receptor (ADRB2) misregulation","volume":"287","author":"Boulay","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2013.09.091_b0090","doi-asserted-by":"crossref","first-page":"5366","DOI":"10.1074\/jbc.M111.329466","article-title":"The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1)","volume":"287","author":"Foveau","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2013.09.091_b0095","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1038\/onc.2010.12","article-title":"A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1","volume":"29","author":"Zhang","year":"2010","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2013.09.091_b0100","doi-asserted-by":"crossref","first-page":"10254","DOI":"10.1074\/jbc.M112.421610","article-title":"DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair","volume":"288","author":"Dehennaut","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2013.09.091_b0105","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.bbrc.2012.11.045","article-title":"Identification of p21 (CIP1\/WAF1) as a direct target gene of HIC1 (Hypermethylated In Cancer 1)","volume":"430","author":"Dehennaut","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2013.09.091_b0110","doi-asserted-by":"crossref","first-page":"10509","DOI":"10.1074\/jbc.M111.320234","article-title":"Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins","volume":"287","author":"Boulay","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2013.09.091_b0115","doi-asserted-by":"crossref","first-page":"38313","DOI":"10.1074\/jbc.M401610200","article-title":"The tumor suppressor gene HIC1 (Hypermethylated In Cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties","volume":"279","author":"Pinte","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2013.09.091_b0120","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.cell.2005.08.011","article-title":"Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses","volume":"123","author":"Chen","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2013.09.091_b0125","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/hmg\/8.4.697","article-title":"Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller\u2013Dieker syndrome","volume":"8","author":"Grimm","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbrc.2013.09.091_b0130","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1101\/gad.1640908","article-title":"Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma","volume":"22","author":"Briggs","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbrc.2013.09.091_b0135","first-page":"3794","article-title":"Hypermethylation of HIC-1 and 17p allelic loss in medulloblastoma","volume":"62","author":"Rood","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2013.09.091_b0140","doi-asserted-by":"crossref","first-page":"e1653","DOI":"10.1371\/journal.pone.0001653","article-title":"The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum","volume":"3","author":"Larouche","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bbrc.2013.09.091_b0145","doi-asserted-by":"crossref","first-page":"e252","DOI":"10.1371\/journal.pone.0000252","article-title":"The pafah1b complex interacts with the Reelin receptor VLDLR","volume":"2","author":"Zhang","year":"2007","journal-title":"PLoS ONE"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X13015842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X13015842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T04:08:51Z","timestamp":1716005331000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X13015842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0006291X13015842"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2013.09.091","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Reelin receptors ApoER2 and VLDLR are direct target genes of HIC1 (Hypermethylated In Cancer 1)","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2013.09.091","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}