{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:27:38Z","timestamp":1789925258987,"version":"4.0.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.bbrc.2013.12.123","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T12:31:53Z","timestamp":1388752313000},"page":"1245-1250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Real-time monitoring of 3T3-L1 preadipocyte differentiation using a commercially available electric cell-substrate impedance sensor system"],"prefix":"10.1016","volume":"443","author":[{"given":"Adam H.","family":"Kramer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Joos-Vandewalle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrienne L.","family":"Edkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carminita L.","family":"Frost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3048-4304","authenticated-orcid":false,"given":"Earl","family":"Prinsloo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2013.12.123_b0005","doi-asserted-by":"crossref","first-page":"6462","DOI":"10.1073\/pnas.1018260108","article-title":"Real-time label-free monitoring of adipose-derived stem cell differentiation with electric cell-substrate impedance sensing","volume":"108","author":"Bagnaninchi","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2013.12.123_b0010","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1039\/c3lc50453k","article-title":"Real-time monitoring of adipocyte differentiation using a capacitance sensor array","volume":"13","author":"Lee","year":"2013","journal-title":"Lab Chip"},{"key":"10.1016\/j.bbrc.2013.12.123_b0015","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1039\/c2lc21236f","article-title":"Capacitance-based assay for real-time monitoring of endocytosis and cell viability","volume":"12","author":"Lee","year":"2012","journal-title":"Lab Chip"},{"key":"10.1016\/j.bbrc.2013.12.123_b0020","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1242\/jcs.61.1.219","article-title":"Morphological changes of the 3T3-L1 fibroblast plasma membrane upon differentiation to the adipocyte form","volume":"61","author":"Fan","year":"1983","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbrc.2013.12.123_b0025","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1109\/TEI.1984.298769","article-title":"Dielectric properties of biological materials: biophysical and medical applications","volume":"EI-19","author":"Pethig","year":"1984","journal-title":"IEEE Trans. Electr. Insul."},{"key":"10.1016\/j.bbrc.2013.12.123_b0030","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0022-3093(02)01132-8","article-title":"Broad frequency range dielectric spectroscopy of aqueous suspensions of phospholipid vesicles","volume":"305","author":"Tirado","year":"2002","journal-title":"J. Non Cryst. Solids"},{"key":"10.1016\/j.bbrc.2013.12.123_b0035","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ab.2012.03.005","article-title":"Protocol for effective differentiation of 3T3-L1 cells to adipocytes","volume":"425","author":"Zebisch","year":"2012","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbrc.2013.12.123_b0040","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ab.2006.12.016","article-title":"Variability in 3T3-L1 adipocyte differentiation depending on cell culture dish","volume":"362","author":"Mehra","year":"2007","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbrc.2013.12.123_b0045","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/j.tiv.2012.08.019","article-title":"A label-free, impedance-based real time assay to identify drug-induced toxicities and differentiate cytostatic from cytotoxic effects","volume":"27","author":"Kustermann","year":"2013","journal-title":"Toxicol. In Vitro"},{"key":"10.1016\/j.bbrc.2013.12.123_b0050","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.nu.14.070194.000531","article-title":"Regulation of adipocyte development","volume":"14","author":"Cornelius","year":"1994","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.bbrc.2013.12.123_b0055","doi-asserted-by":"crossref","first-page":"e46536","DOI":"10.1371\/journal.pone.0046536","article-title":"Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays","volume":"7","author":"Limame","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bbrc.2013.12.123_b0060","series-title":"Advanced Techniques in Diagnostic Microbiology","year":"2013"},{"key":"10.1016\/j.bbrc.2013.12.123_b0065","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/BF00316069","article-title":"Quantification od adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O","volume":"97","author":"Ramirez-Zacarias","year":"1992","journal-title":"Histochemistry"},{"key":"10.1016\/j.bbrc.2013.12.123_b0070","first-page":"67","article-title":"DNA measurement and cell cycle analysis by flow cytometry","volume":"3","author":"Nunez","year":"2001","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.bbrc.2013.12.123_b0075","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2013.12.123_b0080","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1073\/pnas.0137044100","article-title":"Mitotic clonal expansion: a synchronous process required for adipogenesis","volume":"100","author":"Tang","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2013.12.123_b0085","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1002\/pros.20801","article-title":"Translationally regulated C\/EBP beta isoform expression upregulates metastatic genes in hormone-independent prostate cancer cells","volume":"68","author":"Kim","year":"2008","journal-title":"Prostate"},{"key":"10.1016\/j.bbrc.2013.12.123_b0090","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1101\/gad.13.17.2231","article-title":"Activation and centromeric localization of CCAAT\/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation","volume":"13","author":"Tang","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbrc.2013.12.123_b0095","first-page":"57","article-title":"Growth arrest induction of 3T3-L1 preadipocytes by serum starvation and their differentiation by the hormonal adipogenic cocktail","volume":"6","author":"Cao","year":"2012","journal-title":"J. Cell Anim. Biol."},{"key":"10.1016\/j.bbrc.2013.12.123_b0100","doi-asserted-by":"crossref","first-page":"17653","DOI":"10.1074\/jbc.M910445199","article-title":"Mitotic clonal expansion during preadipocyte differentiation: calpain-mediated turnover of p27","volume":"275","author":"Patel","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2013.12.123_b0105","first-page":"3122","article-title":"Adipocyte differentiation and gene expression","author":"Ntambi","year":"2000","journal-title":"Am. Soc. Nutr. Sci."},{"key":"10.1016\/j.bbrc.2013.12.123_b0110","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.nut.2012.07.013","article-title":"Release of a specific set of proinflammatory adipokines by differentiating 3T3-L1 cells","volume":"29","author":"Melloni","year":"2013","journal-title":"Nutrition"},{"key":"10.1016\/j.bbrc.2013.12.123_b0115","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/S0021-9258(19)41881-4","article-title":"Possible role of adenosine cyclic 3\u2032: 5-monophasphate phosphodiesterase in the morphological transformation of chinese hamster ovary cells mediatied by N6, O2\u2032-dibutyryl adenosine cyclic 3\u2032: 5-monophasphate","volume":"250","author":"Hsie","year":"1975","journal-title":"J. Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X13021943?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X13021943?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T09:41:44Z","timestamp":1647855704000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X13021943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0006291X13021943"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2013.12.123","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Real-time monitoring of 3T3-L1 preadipocyte differentiation using a commercially available electric cell-substrate impedance sensor system","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2013.12.123","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}