{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:11:01Z","timestamp":1790806261369,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30830048"],"award-info":[{"award-number":["30830048"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31170711"],"award-info":[{"award-number":["31170711"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81101495"],"award-info":[{"award-number":["81101495"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81230051"],"award-info":[{"award-number":["81230051"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["2009CB521805"],"award-info":[{"award-number":["2009CB521805"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["2010CB529402"],"award-info":[{"award-number":["2010CB529402"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["2010CB912203"],"award-info":[{"award-number":["2010CB912203"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People&apos;s Republic of China","doi-asserted-by":"publisher","award":["2013CB910501"],"award-info":[{"award-number":["2013CB910501"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","award":["BMU20120314"],"award-info":[{"award-number":["BMU20120314"]}],"id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.bbrc.2014.02.087","type":"journal-article","created":{"date-parts":[[2014,2,27]],"date-time":"2014-02-27T01:16:54Z","timestamp":1393463814000},"page":"187-194","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Kindlin-2 inhibits serous epithelial ovarian cancer peritoneal dissemination and predicts patient outcomes"],"prefix":"10.1016","volume":"446","author":[{"given":"Caixia","family":"Ren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenguang","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weigang","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Congrong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongquan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2011","key":"10.1016\/j.bbrc.2014.02.087_b0005","first-page":"212","article-title":"Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths","volume":"61","author":"Siegel","year":"2011","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.bbrc.2014.02.087_b0010","first-page":"161","article-title":"Histologic subtypes of ovarian carcinoma: an overview","volume":"27","author":"Soslow","year":"2008","journal-title":"Int. J. Gynecol. Pathol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0015","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.2353\/ajpath.2010.100105","article-title":"Ovarian cancer development and metastasis","volume":"177","author":"Lengyel","year":"2010","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0020","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1006\/gyno.2001.6232","article-title":"The clinical significance of occult macroscopically positive retroperitoneal nodes in patients with epithelial ovarian cancer","volume":"82","author":"Eisenkop","year":"2001","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0025","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3389\/fonc.2012.00033","article-title":"Epithelial-mesenchymal transition in ovarian carcinoma","volume":"2","author":"Davidson","year":"2012","journal-title":"Front. Oncol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0030","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000147748","article-title":"An overview of epithelio-mesenchymal transformation","volume":"154","author":"Hay","year":"1995","journal-title":"Acta Anat. (Basel)"},{"key":"10.1016\/j.bbrc.2014.02.087_b0035","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.ceb.2005.08.001","article-title":"Molecular requirements for epithelial-mesenchymal transition during tumor progression","volume":"17","author":"Huber","year":"2005","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0040","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/embor.2008.202","article-title":"Kindlins: essential regulators of integrin signalling and cell-matrix adhesion","volume":"9","author":"Larjava","year":"2008","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbrc.2014.02.087_b0045","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1101\/gad.469408","article-title":"Kindlin-2 controls bidirectional signaling of integrins","volume":"22","author":"Montanez","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbrc.2014.02.087_b0050","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1681\/ASN.2012101041","article-title":"Kindlin-2 mediates activation of TGF-beta\/Smad signaling and renal fibrosis","volume":"24","author":"Wei","year":"2013","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0055","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/embor.2012.88","article-title":"Kindlin 2 forms a transcriptional complex with beta-catenin and TCF4 to enhance Wnt signalling","volume":"13","author":"Yu","year":"2012","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbrc.2014.02.087_b0060","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1002\/ijc.28151","article-title":"Kindlin 2 promotes breast cancer invasion via epigenetic silencing of the microRNA200 gene family","volume":"133","author":"Yu","year":"2013","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2014.02.087_b0065","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1158\/1541-7786.MCR-07-2026","article-title":"A suppressive role of mitogen inducible gene-2 in mesenchymal cancer cell invasion","volume":"6","author":"Shi","year":"2008","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.bbrc.2014.02.087_b0070","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/00000478-200404000-00009","article-title":"Grading ovarian serous carcinoma using a two-tier system","volume":"28","author":"Malpica","year":"2004","journal-title":"Am. J. Surg. Pathol."},{"issue":"Suppl. 2","key":"10.1016\/j.bbrc.2014.02.087_b0075","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/S0893-3952(22)04456-8","article-title":"Origins and molecular pathology of ovarian cancer","volume":"18","author":"Bell","year":"2005","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0080","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s00428-012-1203-5","article-title":"Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features","volume":"460","author":"Prat","year":"2012","journal-title":"Virchows Arch."},{"key":"10.1016\/j.bbrc.2014.02.087_b0085","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1002\/ijc.25223","article-title":"Kindlin-2 is expressed in malignant mesothelioma and is required for tumor cell adhesion and migration","volume":"127","author":"An","year":"2010","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2014.02.087_b0090","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/ijc.2910580315","article-title":"Differential expression of the cell-cell adhesion molecule E-cadherin in ascites and solid human ovarian tumor cells","volume":"58","author":"Veatch","year":"1994","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2014.02.087_b0095","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1186\/1471-2407-12-359","article-title":"Protein markers of cancer-associated fibroblasts and tumor-initiating cells reveal subpopulations in freshly isolated ovarian cancer ascites","volume":"12","author":"Wintzell","year":"2012","journal-title":"BMC Cancer"},{"key":"10.1016\/j.bbrc.2014.02.087_b0100","doi-asserted-by":"crossref","first-page":"7420","DOI":"10.1073\/pnas.0903033106","article-title":"ERalpha as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells","volume":"106","author":"Cardamone","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2014.02.087_b0105","doi-asserted-by":"crossref","first-page":"5763","DOI":"10.1158\/0008-5472.CAN-06-4327","article-title":"Activation of FOXO3a by the green tea polyphenol epigallocatechin-3-gallate induces estrogen receptor alpha expression reversing invasive phenotype of breast cancer cells","volume":"67","author":"Belguise","year":"2007","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2014.02.087_b0110","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1210\/me.2007-0293","article-title":"The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha","volume":"21","author":"Dhasarathy","year":"2007","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.bbrc.2014.02.087_b0115","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s12253-010-9340-0","article-title":"Estrogen receptor alpha expression in ovarian cancer predicts longer overall survival","volume":"17","author":"Halon","year":"2011","journal-title":"Pathol. Oncol. Res."},{"key":"10.1016\/j.bbrc.2014.02.087_b0120","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00404-009-1185-y","article-title":"Prognostic significance of estrogen receptor alpha and beta expression in human serous carcinomas of the ovary","volume":"281","author":"Burges","year":"2010","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.bbrc.2014.02.087_b0125","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.amjsurg.2011.06.050","article-title":"Kindlin-2: a novel adhesion protein related to tumor invasion, lymph node metastasis, and patient outcome in gastric cancer","volume":"203","author":"Shen","year":"2012","journal-title":"Am. J. Surg."},{"key":"10.1016\/j.bbrc.2014.02.087_b0130","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.humpath.2003.08.019","article-title":"Expression of the mitogen-inducible gene-2 (mig-2) is elevated in human uterine leiomyomas but not in leiomyosarcomas","volume":"35","author":"Kato","year":"2004","journal-title":"Hum. Pathol."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X14003581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X14003581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T14:28:56Z","timestamp":1762093736000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X14003581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["S0006291X14003581"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2014.02.087","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Kindlin-2 inhibits serous epithelial ovarian cancer peritoneal dissemination and predicts patient outcomes","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2014.02.087","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}