{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:16:11Z","timestamp":1780539371136,"version":"3.54.1"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002850","name":"FONDECYT","doi-asserted-by":"publisher","award":["1130074"],"award-info":[{"award-number":["1130074"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"FONDECYT","doi-asserted-by":"publisher","award":["11110216"],"award-info":[{"award-number":["11110216"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research Office of Universidad Andres Bello","award":["DI-340-13\/R"],"award-info":[{"award-number":["DI-340-13\/R"]}]},{"DOI":"10.13039\/501100008736","name":"Fondo de Fomento al Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["CA13I10077"],"award-info":[{"award-number":["CA13I10077"]}],"id":[{"id":"10.13039\/501100008736","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.bbrc.2015.01.058","type":"journal-article","created":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T07:33:23Z","timestamp":1422430403000},"page":"46-51","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["CysB-dependent upregulation of the Salmonella Typhimurium cysJIH operon in response to antimicrobial compounds that induce oxidative stress"],"prefix":"10.1016","volume":"458","author":[{"given":"Ricardo","family":"\u00c1lvarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"German","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Fr\u00e1vega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"D\u00edaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crist\u00f3bal","family":"Tej\u00edas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo","family":"Collao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan A.","family":"Fuentes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Paredes-Sabja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iv\u00e1n L.","family":"Calder\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Gil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2015.01.058_bib1","first-page":"145","article-title":"Sulfur metabolism in Escherichia coli and related bacteria: facts and fiction","volume":"2","author":"Sekowska","year":"2000","journal-title":"J.\u00a0Mol. Microbiol. Biotechnol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib2","doi-asserted-by":"crossref","first-page":"8953","DOI":"10.1128\/JB.01252-07","article-title":"Cysteine metabolism-related genes and bacterial resistance to potassium tellurite","volume":"189","author":"Fuentes","year":"2007","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib3","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1099\/00221287-8-3-397","article-title":"Hydrogen sulphide production by bacteria","volume":"8","author":"Clarke","year":"1953","journal-title":"J.\u00a0Gen. Microbiol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib4","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1128\/AAC.14.5.765","article-title":"Genetic and molecular characterization of an Escherichia coli plasmid coding for hydrogen sulfide production and drug resistance","volume":"14","author":"Jones","year":"1978","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bbrc.2015.01.058_bib5","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1902\/jop.2009.090012","article-title":"Hydrogen sulfide production from cysteine and homocysteine by periodontal and oral bacteria","volume":"80","author":"Yoshida","year":"2009","journal-title":"J.\u00a0Periodontol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib6","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbrc.2015.01.058_bib7","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1128\/jb.169.6.2391-2397.1987","article-title":"The phs gene and hydrogen sulfide production by Salmonella typhimurium","volume":"169","author":"Clark","year":"1987","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib8","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1089\/ars.2009.2919","article-title":"Hydrogen sulfide: from brain to gut","volume":"12","author":"Kimura","year":"2010","journal-title":"Antioxid. Redox Signal"},{"key":"10.1016\/j.bbrc.2015.01.058_bib9","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1471-4159.2010.06580.x","article-title":"Hydrogen sulfide as a gasotransmitter","volume":"113","author":"Gadalla","year":"2010","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.bbrc.2015.01.058_bib10","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1089\/ars.2009.2938","article-title":"Hydrogen sulfide: the third gasotransmitter in biology and medicine","volume":"12","author":"Wang","year":"2010","journal-title":"Antioxid. Redox Signal"},{"key":"10.1016\/j.bbrc.2015.01.058_bib11","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1126\/science.1209855","article-title":"H2S: a universal defense against antibiotics in bacteria","volume":"18","author":"Shatalin","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2015.01.058_bib12","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1128\/AEM.28.1.22-25.1974","article-title":"Biochemical and antibiotic susceptibility studies of H2S-negative Citrobacter","volume":"28","author":"Lund","year":"1974","journal-title":"Appl. Microbiol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib13","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1128\/jb.171.1.130-140.1989","article-title":"Molecular characterization of the cysJIH promoters of Salmonella typhimurium and Escherichia coli: regulation by CysB protein and N-acetyl-L-serine","volume":"171","author":"Ostrowski","year":"1989","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib14","doi-asserted-by":"crossref","first-page":"6919","DOI":"10.1128\/jb.172.12.6919-6929.1990","article-title":"In\u00a0vitro interactions of CysB protein with the cysK and cysJIH promoter regions of Salmonella typhimurium","volume":"172","author":"Monroe","year":"1990","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib15","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1128\/jb.176.12.3673-3682.1994","article-title":"Stoichiometry of binding of CysB to the cysJIH, cysK, and cysP promoter regions of Salmonella typhimurium","volume":"176","author":"Hryniewicz","year":"1994","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib16","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1099\/13500872-145-1-115","article-title":"Structure and function of a cysBJIH gene cluster in the purple sulphur bacterium Thiocapsa roseopersicina","volume":"145","author":"Haverkamp","year":"1999","journal-title":"Microbiology"},{"key":"10.1016\/j.bbrc.2015.01.058_bib17","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.resmic.2010.06.004","article-title":"Cysteine biosynthesis, oxidative stress and antibiotic resistance in Salmonella typhimurium","volume":"161","author":"Turnbull","year":"2010","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib18","doi-asserted-by":"crossref","first-page":"6640","DOI":"10.1073\/pnas.120163297","article-title":"One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products","volume":"97","author":"Datsenko","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbrc.2015.01.058_bib19","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.bbrc.2014.06.031","article-title":"The small RNA RyhB homologs from Salmonella Typhimurium participate in the response to S-nitrosoglutathione-induced stress","volume":"450","author":"Calder\u00f3n","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2015.01.058_bib20","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0891-5849(99)00266-X","article-title":"Oxidative stress during aging of stationary cultures of the yeast Saccharomyces cerevisiae","volume":"28","author":"Jakubowski","year":"2000","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbrc.2015.01.058_bib21","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1099\/mic.0.066787-0","article-title":"Salmonella enterica serovar Typhimurium BaeSR two-component system positively regulates sodA in response to ciprofloxacin","volume":"159","author":"Guerrero","year":"2013","journal-title":"Microbiology"},{"key":"10.1016\/j.bbrc.2015.01.058_bib22","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sulfhydryl groups","volume":"82","author":"Ellman","year":"1959","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbrc.2015.01.058_bib23","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/nrmicro727","article-title":"Where will new antibiotics come from?","volume":"1","author":"Walsh","year":"2003","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib24","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1086\/381972","article-title":"Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of gram-positive bacterial infections","volume":"38","author":"Pankey","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.bbrc.2015.01.058_bib25","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1146\/annurev.mi.33.100179.000553","article-title":"The mechanism of the irreversible antimicrobial effects of penicillins: how the beta-lactam antibiotics kill and lyse bacteria","volume":"33","author":"Tomasz","year":"1979","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib26","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1128\/MMBR.51.3.341-350.1987","article-title":"Mechanism of bactericidal action of aminoglycosides","volume":"51","author":"Davis","year":"1987","journal-title":"Microbiol. Rev."},{"key":"10.1016\/j.bbrc.2015.01.058_bib27","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1128\/.61.3.377-392.1997","article-title":"DNA gyrase, topoisomerase IV, and the 4-quinolones","volume":"61","author":"Drlica","year":"1997","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.bbrc.2015.01.058_bib28","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/nrmicro2333","article-title":"How antibiotics kill bacteria: from targets to networks","volume":"8","author":"Kohanski","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib29","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.cell.2007.06.049","article-title":"A\u00a0common mechanism of cellular death induced by bactericidal antibiotics","volume":"130","author":"Kohanski","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2015.01.058_bib30","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1046\/j.1365-2958.1996.6301347.x","article-title":"In\u00a0vitro characterization of constitutive CysB proteins from Salmonella typhimurium","volume":"21","author":"Colyer","year":"1996","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/mBio.01442-14","article-title":"Unprecedented high-resolution view of bacterial operon architecture revealed by RNA sequencing","volume":"5","author":"Conway","year":"2014","journal-title":"MBio"},{"key":"10.1016\/j.bbrc.2015.01.058_bib32","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1099\/mic.0.2008\/020347-0","article-title":"L-Cysteine is required for induced antibiotic resistance in actively swarming Salmonella enterica serovar Typhimurium","volume":"154","author":"Turnbull","year":"2008","journal-title":"Microbiology"},{"key":"10.1016\/j.bbrc.2015.01.058_bib33","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1128\/JB.185.6.1942-1950.2003","article-title":"High levels of intracellular cysteine promote oxidative DNA damage by driving the Fenton reaction","volume":"185","author":"Park","year":"2003","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2015.01.058_bib34","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/j.addr.2005.04.002","article-title":"Bacterial resistance to antibiotics: enzymatic degradation and modification","volume":"57","author":"Wright","year":"2005","journal-title":"Adv. Drug. Deliv. Rev."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X15000881?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X15000881?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T11:25:13Z","timestamp":1598700313000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X15000881"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S0006291X15000881"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2015.01.058","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CysB-dependent upregulation of the Salmonella Typhimurium cysJIH operon in response to antimicrobial compounds that induce oxidative stress","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2015.01.058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}