{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T15:57:18Z","timestamp":1790524638894,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30970958"],"award-info":[{"award-number":["30970958"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31401218"],"award-info":[{"award-number":["31401218"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81070481"],"award-info":[{"award-number":["81070481"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002822","name":"Central South University","doi-asserted-by":"publisher","award":["2014JSJJ035"],"award-info":[{"award-number":["2014JSJJ035"]}],"id":[{"id":"10.13039\/501100002822","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.bbrc.2015.12.023","type":"journal-article","created":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T21:35:12Z","timestamp":1450301712000},"page":"501-506","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Snapin interacts with G-protein coupled receptor PKR2"],"prefix":"10.1016","volume":"469","author":[{"given":"Jian","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-die","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Tao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Da","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2015.12.023_bib1","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1124\/mol.59.4.692","article-title":"Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle","volume":"59","author":"Li","year":"2001","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bbrc.2015.12.023_bib2","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1126\/science.1112103","article-title":"Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling","volume":"308","author":"Ng","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2015.12.023_bib3","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.bbrc.2013.08.039","article-title":"Functional analysis of the distal region of the third intracellular loop of PROKR2","volume":"439","author":"Zhou","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2015.12.023_bib4","doi-asserted-by":"crossref","first-page":"16615","DOI":"10.1074\/jbc.M111.223784","article-title":"Disease-causing mutation in PKR2 receptor reveals a critical role of positive charges in the second intracellular loop for G-protein coupling and receptor trafficking","volume":"286","author":"Peng","year":"2011","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1677\/JOE-07-0255","article-title":"Mitogenic functions of endocrine gland-derived vascular endothelial growth factor and Bombina variegata 8 on steroidogenic adrenocortical cells","volume":"196","author":"Keramidas","year":"2008","journal-title":"J.\u00a0Endocrinol."},{"key":"10.1016\/j.bbrc.2015.12.023_bib6","doi-asserted-by":"crossref","first-page":"4140","DOI":"10.1073\/pnas.0508881103","article-title":"Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2","volume":"103","author":"Matsumoto","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbrc.2015.12.023_bib7","doi-asserted-by":"crossref","first-page":"17447","DOI":"10.1073\/pnas.0707173104","article-title":"Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism","volume":"104","author":"Pitteloud","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbrc.2015.12.023_bib8","doi-asserted-by":"crossref","first-page":"15518","DOI":"10.1074\/jbc.M114.556381","article-title":"Functional rescue of Kallmann syndrome- associated prokineticin receptor 2 (PKR2) mutants deficient in trafficking","volume":"289","author":"Chen","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib9","doi-asserted-by":"crossref","first-page":"11615","DOI":"10.1523\/JNEUROSCI.3679-06.2006","article-title":"Attenuated circadian rhythms in mice lacking the prokineticin 2 gene","volume":"26","author":"Li","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.bbrc.2015.12.023_bib10","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0898-6568(01)00203-0","article-title":"Beta-Arrestins: new roles in regulating heptahelical receptors' functions","volume":"13","author":"McDonald","year":"2001","journal-title":"Cell Signal."},{"key":"10.1016\/j.bbrc.2015.12.023_bib11","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/nrm908","article-title":"Seven-transmembrane receptors","volume":"3","author":"Pierce","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.bbrc.2015.12.023_bib12","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1042\/bj20031076","article-title":"Multifaceted roles of beta-arrestins in the regulation of seven- membrane-spanning receptor trafficking and signalling","volume":"375","author":"Shenoy","year":"2003","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2015.12.023_bib13","doi-asserted-by":"crossref","first-page":"14498","DOI":"10.1074\/jbc.M209626200","article-title":"Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination","volume":"278","author":"Shenoy","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib14","doi-asserted-by":"crossref","first-page":"19276","DOI":"10.1074\/jbc.M202139200","article-title":"Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins\/endocrine gland vascular endothelial growth factor","volume":"277","author":"Lin","year":"2002","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib15","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/5673","article-title":"Snapin: a SNARE-associated protein implicated in synaptic transmission","volume":"2","author":"Ilardi","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2015.12.023_bib16","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1042\/bj20030427","article-title":"Identification and characterization of Snapin as a ubiquitously expressed SNARE-binding protein that interacts with SNAP23 in non-neuronal cells","volume":"375","author":"Buxton","year":"2003","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbrc.2015.12.023_bib17","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1242\/jcs.02936","article-title":"Ryanodine receptor interaction with the SNARE-associated protein snapin","volume":"119","author":"Zissimopoulos","year":"2006","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.bbrc.2015.12.023_bib18","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/45816","article-title":"A\u00a0kinase-regulated PDZ- domain interaction controls endocytic sorting of the beta2-adrenergic receptor","volume":"401","author":"Cao","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2015.12.023_bib19","doi-asserted-by":"crossref","first-page":"45145","DOI":"10.1074\/jbc.M106087200","article-title":"Binding of the beta2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recycling","volume":"276","author":"Cong","year":"2001","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib20","doi-asserted-by":"crossref","first-page":"54291","DOI":"10.1074\/jbc.M406169200","volume":"279","author":"Heydorn","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib21","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1074\/jbc.M406934200","article-title":"Type I PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor","volume":"280","author":"Gage","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib22","doi-asserted-by":"crossref","first-page":"27545","DOI":"10.1074\/jbc.M200058200","article-title":"Ezrin-radixin-moesin-binding phosphoprotein-50\/Na+\/H+ exchanger regulatory factor (EBP50\/NHERF) blocks U50,488H-induced down-regulation of the human kappa opioid receptor by enhancing its recycling rate","volume":"277","author":"Li","year":"2002","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib23","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1126\/science.1073308","article-title":"Modulation of postendocytic sorting of G protein-coupled receptors","volume":"297","author":"Whistler","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2015.12.023_bib24","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1091\/mbc.E01-11-0131","article-title":"Down-regulation of protease-activated receptor-1 is regulated by sorting nexin 1","volume":"13","author":"Wang","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbrc.2015.12.023_bib25","doi-asserted-by":"crossref","first-page":"10408","DOI":"10.1074\/jbc.M209655200","article-title":"Binding of filamin to the C-terminal tail of the calcitonin receptor controls recycling","volume":"278","author":"Seck","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib26","doi-asserted-by":"crossref","first-page":"49348","DOI":"10.1074\/jbc.M306557200","article-title":"GIPC binds to the human lutropin receptor (hLHR) through an unusual PDZ domain binding motif, and it regulates the sorting of the internalized human choriogonadotropin and the density of cell surface hLHR","volume":"278","author":"Hirakawa","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib27","doi-asserted-by":"crossref","first-page":"35687","DOI":"10.1074\/jbc.M402751200","article-title":"Crucial role of neuron-enriched endosomal protein of 21 kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors","volume":"279","author":"Debaigt","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2015.12.023_bib28","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1093\/emboj\/18.7.1723","article-title":"Molecular tinkering of G protein-coupled receptors: an evolutionary success","volume":"18","author":"Bockaert","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2015.12.023_bib29","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.sbi.2010.05.002","article-title":"The crystallographic structure of the human adenosine A2A receptor in a high-affinity antagonist-bound state: implications for GPCR drug screening and design","volume":"20","author":"Jaakola","year":"2010","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.bbrc.2015.12.023_bib30","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.cellsig.2014.01.031","article-title":"Mechanisms that underlie the internalization and extracellular signal regulated kinase 1\/2 activation by PKR2 receptor","volume":"26","author":"Yin","year":"2014","journal-title":"Cell Signal."},{"key":"10.1016\/j.bbrc.2015.12.023_bib31","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0014-5793(03)00453-8","article-title":"The \u2018magic tail\u2019 of G protein-coupled receptors: an anchorage for functional protein networks","volume":"546","author":"Bockaert","year":"2003","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbrc.2015.12.023_bib32","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.semcdb.2003.12.018","article-title":"Identification and functional roles of metabotropic glutamate receptor-interacting proteins","volume":"15","author":"Fagni","year":"2004","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.bbrc.2015.12.023_bib33","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1038\/nn1134","article-title":"PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis","volume":"6","author":"Rong","year":"2003","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2015.12.023_bib34","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0166-2236(99)01492-7","article-title":"Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons","volume":"23","author":"Fagni","year":"2000","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.bbrc.2015.12.023_bib35","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.15252\/embj.201591125","article-title":"Regulation of synaptic activity by snapin-mediated endolysosomal transport and sorting","volume":"34","author":"Di Giovanni","year":"2015","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2015.12.023_bib36","doi-asserted-by":"crossref","first-page":"445","DOI":"10.4161\/auto.7.4.14682","article-title":"Uncovering the role of Snapin in regulating autophagy-lysosomal function","volume":"7","author":"Cai","year":"2011","journal-title":"Autophagy"},{"key":"10.1016\/j.bbrc.2015.12.023_bib37","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1083\/jcb.201412046","article-title":"Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes","volume":"209","author":"Cheng","year":"2015","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.bbrc.2015.12.023_bib38","doi-asserted-by":"crossref","first-page":"29563","DOI":"10.1074\/jbc.M702063200","article-title":"Snapin, a new regulator of receptor signaling, augments alpha1A-adrenoceptor-operated calcium influx through TRPC6","volume":"282","author":"Suzuki","year":"2007","journal-title":"J.\u00a0Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X15310305?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X15310305?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T15:53:43Z","timestamp":1567439623000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X15310305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S0006291X15310305"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2015.12.023","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Snapin interacts with G-protein coupled receptor PKR2","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2015.12.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}