{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:52:37Z","timestamp":1781661157295,"version":"3.54.5"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000317","name":"Action Medical Research","doi-asserted-by":"crossref","award":["SP4612"],"award-info":[{"award-number":["SP4612"]}],"id":[{"id":"10.13039\/501100000317","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.bbrc.2016.12.047","type":"journal-article","created":{"date-parts":[[2016,12,10]],"date-time":"2016-12-10T01:54:54Z","timestamp":1481334894000},"page":"1393-1399","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Phosphorylation of proteins during human myometrial contractions: A phosphoproteomic approach"],"prefix":"10.1016","volume":"482","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5588-8196","authenticated-orcid":false,"given":"Claire A.","family":"Hudson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"L\u00f3pez Bernal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2016.12.047_bib1","doi-asserted-by":"crossref","first-page":"21596","DOI":"10.1016\/S0021-9258(17)31846-X","article-title":"Activation properties of myosin light chain kinase during contraction\/relaxation cycles of tonic and phasic smooth muscles","volume":"269","author":"Word","year":"1994","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2016.12.047_bib2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/molehr\/gar078","article-title":"Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1)","volume":"18","author":"Hudson","year":"2012","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.bbrc.2016.12.047_bib3","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s004240000305","article-title":"The effects of inhibiting myosin light chain kinase on contraction and calcium signalling in human and rat myometrium","volume":"440","author":"Longbottom","year":"2000","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.bbrc.2016.12.047_bib4","doi-asserted-by":"crossref","first-page":"e21542","DOI":"10.1371\/journal.pone.0021542","article-title":"Phasic phosphorylation of caldesmon and ERK 1\/2 during contractions in human myometrium","volume":"6","author":"Paul","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2016.12.047_bib5","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1210\/en.2007-0662","article-title":"Contraction in human myometrium is associated with changes in small heat shock proteins","volume":"149","author":"MacIntyre","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbrc.2016.12.047_bib6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1155\/2014\/767812","article-title":"Cardiac phosphoproteomics during remote ischemic preconditioning: a role for the sarcomeric z-disk proteins","volume":"2014","author":"Abdul-Ghani","year":"2014","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.bbrc.2016.12.047_bib7","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/molehr\/gaw031","article-title":"Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium","volume":"22","author":"Hudson","year":"2016","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.bbrc.2016.12.047_bib8","doi-asserted-by":"crossref","first-page":"3178","DOI":"10.1016\/S0021-9258(19)69586-4","article-title":"The relationship between calmodulin binding and phosphorylation of smooth muscle myosin kinase by the catalytic subunit of 3':5' cAMP-dependent protein kinase","volume":"256","author":"Conti","year":"1981","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2016.12.047_bib9","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1146\/annurev.pa.25.040185.003113","article-title":"The function of myosin and myosin light chain kinase phosphorylation in smooth muscle","volume":"25","author":"Kamm","year":"1985","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bbrc.2016.12.047_bib10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1146\/annurev.ph.51.030189.001503","article-title":"Regulation of smooth muscle contractile elements by second messengers","volume":"51","author":"Kamm","year":"1989","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.bbrc.2016.12.047_bib11","first-page":"39","article-title":"Prostaglandin E receptors in myometrial cells","volume":"85","author":"Asboth","year":"1997","journal-title":"Acta Physiol. Hung."},{"key":"10.1016\/j.bbrc.2016.12.047_bib12","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/0006-291X(91)90898-H","article-title":"Oxytocin contracts rat uterine smooth muscle in Ca2+-free medium without any phosphorylation of myosin light chain","volume":"176","author":"Oishi","year":"1991","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2016.12.047_bib13","doi-asserted-by":"crossref","first-page":"e0153780","DOI":"10.1371\/journal.pone.0153780","article-title":"MEF2C-MYOCD and Leiomodin1 suppression by miRNA-214 promotes smooth muscle cell phenotype switching in pulmonary arterial hypertension","volume":"11","author":"Sahoo","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2016.12.047_bib14","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1096\/fj.15-279158","article-title":"Ca2+\/calmodulin-dependent protein kinase II-gamma (CaMKIIgamma) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling","volume":"30","author":"Saddouk","year":"2016","journal-title":"FASEB J."},{"key":"10.1016\/j.bbrc.2016.12.047_bib15","doi-asserted-by":"crossref","first-page":"R256","DOI":"10.1152\/ajpregu.00145.2014","article-title":"A\u00a0bioinformatic and computational study of myosin phosphatase subunit diversity","volume":"307","author":"Dippold","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bbrc.2016.12.047_bib16","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1530\/REP-09-0160","article-title":"RHO protein regulation of contraction in the human uterus","volume":"138","author":"Lartey","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.bbrc.2016.12.047_bib17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.cardiores.2006.09.001","article-title":"Ahnak, a new player in beta-adrenergic regulation of the cardiac L-type Ca2+ channel","volume":"73","author":"Haase","year":"2007","journal-title":"Cardiovasc Res."},{"key":"10.1016\/j.bbrc.2016.12.047_bib18","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1096\/fj.01-0855com","article-title":"The carboxyl-terminal region of ahnak provides a link between cardiac L-type Ca2+ channels and the actin-based cytoskeleton","volume":"16","author":"Hohaus","year":"2002","journal-title":"Faseb J."},{"issue":"1","key":"10.1016\/j.bbrc.2016.12.047_bib19","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/j.ejogrb.2009.02.010","article-title":"A\u00a0review of recent insights into the role of the sarcoplasmic reticulum and Ca entry in uterine smooth muscle","volume":"144","author":"Noble","year":"2009","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.bbrc.2016.12.047_bib20","doi-asserted-by":"crossref","first-page":"617","DOI":"10.4067\/S0716-97602004000400017","article-title":"Ca2+ entry, efflux and release in smooth muscle","volume":"37","author":"Matthew","year":"2004","journal-title":"Biol. Res."},{"key":"10.1016\/j.bbrc.2016.12.047_bib21","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1476-5381.1978.tb08636.x","article-title":"The action of bradykinin and oxytocin on the isolated whole uterus and myometrium of the rat in oestrus","volume":"64","author":"Whalley","year":"1978","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2016.12.047_bib22","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1385\/ENDO:16:3:207","article-title":"Tissue kallikrein and bradykinin B2 receptor in human uterus in luteal phase and in early and late gestation","volume":"16","author":"Valdes","year":"2001","journal-title":"Endocrine"},{"issue":"7","key":"10.1016\/j.bbrc.2016.12.047_bib23","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/molehr\/gaw031","article-title":"Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium","volume":"22","author":"Hudson","year":"2016","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.bbrc.2016.12.047_bib24","doi-asserted-by":"crossref","first-page":"8975","DOI":"10.1016\/S0021-9258(19)38796-4","article-title":"Phosphorylation of smooth myosin light chain kinase by smooth muscle Ca2+\/calmodulin-dependent multifunctional protein kinase","volume":"265","author":"Ikebe","year":"1990","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2016.12.047_bib25","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/BF01076774","article-title":"Phosphorylation of myosin light chain kinase: a cellular mechanism for Ca2+ desensitization","volume":"127\u2013128","author":"Stull","year":"1993","journal-title":"Mol. Cell Biochem."},{"key":"10.1016\/j.bbrc.2016.12.047_bib26","doi-asserted-by":"crossref","first-page":"11873","DOI":"10.1016\/S0021-9258(17)32654-6","article-title":"Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype","volume":"269","author":"Bastien","year":"1994","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2016.12.047_bib27","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.semcdb.2007.05.002","article-title":"The regulation of uterine relaxation","volume":"18","author":"Lopez Bernal","year":"2007","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.bbrc.2016.12.047_bib28","doi-asserted-by":"crossref","first-page":"R525","DOI":"10.1152\/ajpregu.00153.2009","article-title":"Are animal models relevant to key aspects of human parturition?","volume":"297","author":"Mitchell","year":"2009","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bbrc.2016.12.047_bib29","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.semcdb.2007.05.008","article-title":"Potassium channels and uterine function","volume":"18","author":"Brainard","year":"2007","journal-title":"Semin. Cell Dev. Biol."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X16320915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X16320915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,16]],"date-time":"2022-07-16T20:32:10Z","timestamp":1658003530000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X16320915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S0006291X16320915"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2016.12.047","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phosphorylation of proteins during human myometrial contractions: A phosphoproteomic approach","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2016.12.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}