{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:14:32Z","timestamp":1790219672209,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001677","name":"INSERM","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","award":["FP-7 HEALTH 603228 SYSVASC"],"award-info":[{"award-number":["FP-7 HEALTH 603228 SYSVASC"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Europe (ERASMUS MUNDUS, MEDEA)"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.bbrc.2017.04.026","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T18:19:02Z","timestamp":1491589142000},"page":"109-115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Increased urine acylcarnitines in diabetic ApoE -\/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia"],"prefix":"10.1016","volume":"487","author":[{"given":"Koryun","family":"Mirzoyan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristaps","family":"Klavins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese","family":"Koal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Gillet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitri","family":"Marsal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colette","family":"Denis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Loup","family":"Bascands","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joost P.","family":"Schanstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-S\u00e9bastien","family":"Saulnier-Blache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2017.04.026_bib1","doi-asserted-by":"publisher","first-page":"2005","DOI":"10.1016\/S0140-6736(03)13636-7","article-title":"Heart Protection Study Collaborative, MRC\/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial","volume":"361","author":"Collins","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.bbrc.2017.04.026_bib2","first-page":"S125","article-title":"Hypercholesterolemia\u2013a determinant of renal function loss and deaths in IDDM patients with nephropathy","volume":"45","author":"Krolewski","year":"1994","journal-title":"Kidney Int. Suppl."},{"key":"10.1016\/j.bbrc.2017.04.026_bib3","doi-asserted-by":"publisher","first-page":"S87","DOI":"10.1111\/j.1523-1755.2005.09916.x","article-title":"Dyslipidemia and the progression of renal disease in chronic renal failure patients","author":"Cases","year":"2005","journal-title":"Kidney Int. Suppl."},{"key":"10.1016\/j.bbrc.2017.04.026_bib4","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1097\/01.LAB.0000022222.03120.D4","article-title":"Renal injury in apolipoprotein E-deficient mice","volume":"82","author":"Wen","year":"2002","journal-title":"Lab. Invest"},{"key":"10.1016\/j.bbrc.2017.04.026_bib5","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1046\/j.1523-1755.2001.00487.x","article-title":"Effect of lipid reduction on the progression of renal disease: a meta-analysis","volume":"59","author":"Fried","year":"2001","journal-title":"Kidney Int."},{"key":"10.1016\/j.bbrc.2017.04.026_bib6","doi-asserted-by":"publisher","first-page":"S31","DOI":"10.1046\/j.1523-1755.1999.07109.x","article-title":"Role of hyperlipidemia in progressive renal disease: focus on diabetic nephropathy","volume":"71","author":"Jandeleit-Dahm","year":"1999","journal-title":"Kidney Int. Suppl."},{"key":"10.1016\/j.bbrc.2017.04.026_bib7","doi-asserted-by":"publisher","first-page":"2125","DOI":"10.1097\/01.ASN.0000133025.23732.46","article-title":"Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products","volume":"15","author":"Lassila","year":"2004","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.bbrc.2017.04.026_bib8","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1681\/ASN.2013020126","article-title":"Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease","volume":"24","author":"Sharma","year":"2013","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.bbrc.2017.04.026_bib9","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1681\/ASN.2004080648","article-title":"Amdcc, Mouse models of diabetic nephropathy","volume":"16","author":"Breyer","year":"2005","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.bbrc.2017.04.026_bib10","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1172\/JCI0215493","article-title":"In\u00a0vivo bradykinin B2 receptor activation reduces renal fibrosis","volume":"110","author":"Schanstra","year":"2002","journal-title":"J.\u00a0Clin. Invest"},{"key":"10.1016\/j.bbrc.2017.04.026_bib11","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.dadm.2015.05.003","article-title":"The ratio of phosphatidylcholines to lysophosphatidylcholines in plasma differentiates healthy controls from patients with Alzheimer's disease and mild cognitive impairment","volume":"1","author":"Klavins","year":"2015","journal-title":"Alzheimers Dement. (Amst)"},{"key":"10.1016\/j.bbrc.2017.04.026_bib12","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.3233\/JAD-142319","article-title":"Sphingomyelin SM(d18:1\/18:0) is significantly enhanced in cerebrospinal fluid samples dichotomized by pathological amyloid-beta42, tau, and phospho-tau-181 levels","volume":"44","author":"Koal","year":"2015","journal-title":"J.\u00a0Alzheimers Dis."},{"key":"10.1016\/j.bbrc.2017.04.026_bib13","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s13105-013-0238-7","article-title":"Influence of secreted factors from human adipose tissue on glucose utilization and proinflammatory reaction","volume":"69","author":"Treguer","year":"2013","journal-title":"J.\u00a0Physiol. Biochem."},{"key":"10.1016\/j.bbrc.2017.04.026_bib14","doi-asserted-by":"publisher","first-page":"2029","DOI":"10.1194\/jlr.D061721","article-title":"An LC-MS\/MS method to quantify acylcarnitine species including isomeric and odd-numbered forms in plasma and tissues","volume":"56","author":"Giesbertz","year":"2015","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.bbrc.2017.04.026_bib15","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1074\/jbc.M209261200","article-title":"Metabolic functions of the two pathways of oleate beta-oxidation double bond metabolism during the beta-oxidation of oleic acid in rat heart mitochondria","volume":"278","author":"Ren","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2017.04.026_bib16","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1146\/annurev-physiol-021115-105045","article-title":"The biochemistry and physiology of mitochondrial fatty acid beta-oxidation and its genetic disorders","volume":"78","author":"Houten","year":"2016","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.bbrc.2017.04.026_bib17","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/ajcn\/79.2.185","article-title":"Renal metabolism of amino acids: its role in interorgan amino acid exchange","volume":"79","author":"van de Poll","year":"2004","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bbrc.2017.04.026_bib18","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1007\/s11892-015-0611-8","article-title":"The evolving understanding of the contribution of lipid metabolism to diabetic kidney disease","volume":"15","author":"Stadler","year":"2015","journal-title":"Curr. Diab Rep."},{"key":"10.1016\/j.bbrc.2017.04.026_bib19","doi-asserted-by":"publisher","first-page":"E287","DOI":"10.1152\/ajpendo.00308.2010","article-title":"Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes","volume":"300","author":"Zhang","year":"2011","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbrc.2017.04.026_bib20","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/0305-0491(84)90001-4","article-title":"Carnitine ester hydrolysis in arteries from normal and cholesterol-fed rabbits and the effects of carnitine esters on arterial microsomal ACAT","volume":"79","author":"Bell","year":"1984","journal-title":"Comp. Biochem. Physiol. B"},{"key":"10.1016\/j.bbrc.2017.04.026_bib21","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1111\/j.1365-2265.2011.04244.x","article-title":"The association of specific metabolites of lipid metabolism with markers of oxidative stress, inflammation and arterial stiffness in men with newly diagnosed type 2 diabetes","volume":"76","author":"Ha","year":"2012","journal-title":"Clin. Endocrinol. (Oxf)"},{"key":"10.1016\/j.bbrc.2017.04.026_bib22","doi-asserted-by":"publisher","first-page":"e82459","DOI":"10.1371\/journal.pone.0082459","article-title":"Serum levels of acylcarnitines are altered in prediabetic conditions","volume":"8","author":"Mai","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2017.04.026_bib23","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/nm.3762","article-title":"Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development","volume":"21","author":"Kang","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2017.04.026_bib24","doi-asserted-by":"publisher","first-page":"4888","DOI":"10.1172\/JCI66218","article-title":"AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function","volume":"123","author":"Dugan","year":"2013","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.bbrc.2017.04.026_bib25","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1194\/jlr.P040501","article-title":"Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy","volume":"55","author":"Herman-Edelstein","year":"2014","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.bbrc.2017.04.026_bib26","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1093\/ajh\/hpt268","article-title":"L-carnitine attenuates the development of kidney fibrosis in hypertensive rats by upregulating PPAR-gamma","volume":"27","author":"Zambrano","year":"2014","journal-title":"Am. J. Hypertens."},{"key":"10.1016\/j.bbrc.2017.04.026_bib27","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1016\/j.celrep.2016.04.037","article-title":"Renal Fanconi syndrome is caused by a mistargeting-based mitochondriopathy","volume":"15","author":"Assmann","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2017.04.026_bib28","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1056\/NEJMoa1307581","article-title":"Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome","volume":"370","author":"Klootwijk","year":"2014","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.bbrc.2017.04.026_bib29","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1111\/jvim.12086","article-title":"Prospective evaluation of biweekly streptozotocin in 19 dogs with insulinoma","volume":"27","author":"Northrup","year":"2013","journal-title":"J.\u00a0Vet. Intern Med."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X17306824?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X17306824?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T01:07:17Z","timestamp":1601860037000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X17306824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0006291X17306824"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2017.04.026","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased urine acylcarnitines in diabetic ApoE-\/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2017.04.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}