{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T22:56:40Z","timestamp":1773701800684,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.bbrc.2017.08.031","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T14:32:18Z","timestamp":1502375538000},"page":"161-165","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Canagliflozin potentiates GLP-1 secretion and lowers the peak of GIP secretion in rats fed a high-fat high-sucrose diet"],"prefix":"10.1016","volume":"492","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0354-1617","authenticated-orcid":false,"given":"Tohru","family":"Hira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiki","family":"Koga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyo","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2017.08.031_bib1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.2337\/db14-1514","article-title":"Deciphering metabolic messages from the gut drives therapeutic innovation: the 2014 Banting Lecture","volume":"64","author":"Drucker","year":"2015","journal-title":"Diabetes"},{"key":"10.1016\/j.bbrc.2017.08.031_bib2","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/ijo.2012.208","article-title":"Incretin hormones and the satiation signal","volume":"37","author":"Holst","year":"2013","journal-title":"Int. J. Obes. (Lond)"},{"key":"10.1016\/j.bbrc.2017.08.031_bib3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cmet.2006.01.004","article-title":"The biology of incretin hormones","volume":"3","author":"Drucker","year":"2006","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbrc.2017.08.031_bib4","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1038\/nm727","article-title":"Inhibition of gastric inhibitory polypeptide signaling prevents obesity","volume":"8","author":"Miyawaki","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2017.08.031_bib5","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3177\/jnsv.57.30","article-title":"GLP-1 secretion in response to oral and luminal palatinose (isomaltulose) in rats","volume":"57","author":"Hira","year":"2011","journal-title":"J.\u00a0Nutr. Sci. Vitaminol. (Tokyo)"},{"key":"10.1016\/j.bbrc.2017.08.031_bib6","doi-asserted-by":"crossref","first-page":"G663","DOI":"10.1152\/ajpgi.90635.2008","article-title":"GLP-1 secretion is enhanced directly in the ileum but indirectly in the duodenum by a newly identified potent stimulator, zein hydrolysate, in rats","volume":"297","author":"Hira","year":"2009","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.bbrc.2017.08.031_bib7","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1210\/en.2009-1510","article-title":"The corn protein, zein hydrolysate, administered into the ileum attenuates hyperglycemia via its dual action on glucagon-like peptide-1 secretion and dipeptidyl peptidase-IV activity in rats","volume":"151","author":"Mochida","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbrc.2017.08.031_bib8","article-title":"Resistant maltodextrin or fructooligosaccharides promotes GLP-1 production in male rats fed a high-fat and high-sucrose diet, and partially reduces energy intake and adiposity","author":"Hira","year":"2017","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.bbrc.2017.08.031_bib9","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.2147\/DDDT.S50773","article-title":"Update on developments with SGLT2 inhibitors in the management of type 2 diabetes","volume":"8","author":"Nauck","year":"2014","journal-title":"Drug Des. Devel Ther."},{"key":"10.1016\/j.bbrc.2017.08.031_bib10","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/nyas.12852","article-title":"Canagliflozin: a sodium glucose co-transporter 2 inhibitor for the treatment of type 2 diabetes mellitus","volume":"1358","author":"Rosenthal","year":"2015","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbrc.2017.08.031_bib11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1463-1326.2011.01517.x","article-title":"Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors","volume":"14","author":"Grempler","year":"2012","journal-title":"Diabetes Obes. Metab."},{"key":"10.1016\/j.bbrc.2017.08.031_bib12","doi-asserted-by":"crossref","first-page":"e30555","DOI":"10.1371\/journal.pone.0030555","article-title":"Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models","volume":"7","author":"Liang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2017.08.031_bib13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2337\/db11-1029","article-title":"Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion","volume":"61","author":"Gorboulev","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.bbrc.2017.08.031_bib14","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s00125-008-1202-x","article-title":"Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells","volume":"52","author":"Parker","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbrc.2017.08.031_bib15","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1152\/physrev.00055.2009","article-title":"Biology of human sodium glucose transporters","volume":"91","author":"Wright","year":"2011","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbrc.2017.08.031_bib16","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1124\/jpet.115.225508","article-title":"Intestinal sodium glucose cotransporter 1 inhibition enhances glucagon-like Peptide-1 secretion in normal and diabetic rodents","volume":"354","author":"Oguma","year":"2015","journal-title":"J.\u00a0Pharmacol. Exp. Ther."},{"key":"10.1016\/j.bbrc.2017.08.031_bib17","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.jphs.2015.03.006","article-title":"The effect of combined treatment with canagliflozin and teneligliptin on glucose intolerance in Zucker diabetic fatty rats","volume":"127","author":"Oguma","year":"2015","journal-title":"J.\u00a0Pharmacol. Sci."},{"key":"10.1016\/j.bbrc.2017.08.031_bib18","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jphs.2016.10.006","article-title":"Changes in glucose-induced plasma active glucagon-like peptide-1 levels by co-administration of sodium-glucose cotransporter inhibitors with dipeptidyl peptidase-4 inhibitors in rodents","volume":"132","author":"Oguma","year":"2016","journal-title":"J.\u00a0Pharmacol. Sci."},{"key":"10.1016\/j.bbrc.2017.08.031_bib19","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.2337\/dc12-2391","article-title":"Canagliflozin lowers postprandial glucose and insulin by delaying intestinal glucose absorption in addition to increasing urinary glucose excretion: results of a randomized, placebo-controlled study","volume":"36","author":"Polidori","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.bbrc.2017.08.031_bib20","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1017\/S0007114515000550","article-title":"Postprandial glucagon-like peptide-1 secretion is increased during the progression of glucose intolerance and obesity in high-fat\/high-sucrose diet-fed rats","volume":"113","author":"Nakajima","year":"2015","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bbrc.2017.08.031_bib21","doi-asserted-by":"crossref","first-page":"838s","DOI":"10.1093\/jn\/127.5.838S","article-title":"Components of the AIN-93 diets as improvements in the AIN-76A diet","volume":"127","author":"Reeves","year":"1997","journal-title":"J.\u00a0Nutr."},{"key":"10.1016\/j.bbrc.2017.08.031_bib22","doi-asserted-by":"crossref","first-page":"e0126157","DOI":"10.1371\/journal.pone.0126157","article-title":"The anthocyanin delphinidin 3-rutinoside stimulates glucagon-like Peptide-1 secretion in murine GLUTag cell line via the Ca2+\/Calmodulin-Dependent kinase II pathway","volume":"10","author":"Kato","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2017.08.031_bib23","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0167-0115(03)00125-3","article-title":"GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine","volume":"114","author":"Mortensen","year":"2003","journal-title":"Regul. Pept."},{"key":"10.1016\/j.bbrc.2017.08.031_bib24","doi-asserted-by":"crossref","first-page":"2706","DOI":"10.1210\/jc.2002-021873","article-title":"Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus","volume":"88","author":"Vilsboll","year":"2003","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bbrc.2017.08.031_bib25","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.bbrc.2015.09.130","article-title":"Yhhu4488, a novel GPR40 agonist, promotes GLP-1 secretion and exerts anti-diabetic effect in rodent models","volume":"466","author":"Guo","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2017.08.031_bib26","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.bbrc.2016.04.149","article-title":"A\u00a0bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells","volume":"475","author":"Pham","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2017.08.031_bib27","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1152\/japplphysiol.00268.2014","article-title":"Triterpene alcohols and sterols from rice bran lower postprandial glucose-dependent insulinotropic polypeptide release and prevent diet-induced obesity in mice","volume":"117","author":"Fukuoka","year":"2014","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.bbrc.2017.08.031_bib28","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1210\/en.2014-1710","article-title":"An analysis of cosecretion and coexpression of gut hormones from male rat proximal and distal small intestine","volume":"156","author":"Svendsen","year":"2015","journal-title":"Endocrinology"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X17315760?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X17315760?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T10:48:45Z","timestamp":1574938125000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X17315760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0006291X17315760"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2017.08.031","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Canagliflozin potentiates GLP-1 secretion and lowers the peak of GIP secretion in rats fed a high-fat high-sucrose diet","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2017.08.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}