{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T08:01:07Z","timestamp":1779177667369,"version":"3.51.4"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81471282"],"award-info":[{"award-number":["81471282"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.bbrc.2018.01.020","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T00:03:16Z","timestamp":1515110596000},"page":"260-266","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Glial cell-derived neurotrophic factor alleviates sepsis-induced neuromuscular dysfunction by decreasing the expression of \u03b3- and \u03b17-nicotinic acetylcholine receptors in an experimental rat model of neuromyopathy"],"prefix":"10.1016","volume":"496","author":[{"given":"Xin","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8906-681X","authenticated-orcid":false,"given":"Su","family":"Min","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2018.01.020_bib1","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"J.\u00a0Am. Med. Assoc."},{"key":"10.1016\/j.bbrc.2018.01.020_bib2","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.immuni.2014.04.001","article-title":"Sepsis: current dogma and new perspectives","volume":"40","author":"Deutschman","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.bbrc.2018.01.020_bib3","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/7897325","article-title":"Skeletal muscle and lymphocyte mitochondrial dysfunctions in septic shock trigger ICU-acquired weakness and sepsis-induced immunoparalysis","volume":"2017","author":"Maestraggi","year":"2017","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.bbrc.2018.01.020_bib4","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/jor.20773","article-title":"How age impairs the response of the neuromuscular junction to nerve transection and repair: an experimental study in rats","volume":"27","author":"Apel","year":"2009","journal-title":"J.\u00a0Orthop. Res."},{"key":"10.1016\/j.bbrc.2018.01.020_bib5","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/bja\/aet253","article-title":"Pharmacodynamic changes with vecuronium in sepsis are associated with expression of \u03b17- and \u03b3-nicotinic acetylcholine receptor in an experimental rat model of neuromyopathy","volume":"112","author":"Liu","year":"2014","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.bbrc.2018.01.020_bib6","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00540-012-1527-y","article-title":"Synergistic effect of sevoflurane and isoflurane on inhibition of the adult-type muscle nicotinic acetylcholine receptor by rocuronium","volume":"27","author":"Liu","year":"2013","journal-title":"J.\u00a0Anesth."},{"key":"10.1016\/j.bbrc.2018.01.020_bib7","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1113\/EP086049","article-title":"Effects of exercise training on brain-derived neurotrophic factor in skeletal muscle and heart of rats post myocardial infarction","volume":"102","author":"Lee","year":"2017","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.bbrc.2018.01.020_bib8","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2174\/156720506775697061","article-title":"Dissecting the diverse actions of pro- and mature neurotrophins","volume":"3","author":"Hempstead","year":"2006","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.bbrc.2018.01.020_bib9","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1126\/science.8493557","article-title":"GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons","volume":"260","author":"Lin","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2018.01.020_bib10","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.aanat.2014.03.001","article-title":"GDNF and GFR\u03b1 co-receptor family in the developing feline gut","volume":"196","author":"Maruccio","year":"2014","journal-title":"Ann. Anat."},{"key":"10.1016\/j.bbrc.2018.01.020_bib11","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.expneurol.2016.01.008","article-title":"Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS)","volume":"277","author":"Van Dyke","year":"2016","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbrc.2018.01.020_bib12","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1177\/0963689717721202","article-title":"Simultaneous transplantation of fetal ventral mesencephalic tissue and encapsulated genetically modified cells releasing GDNF in a hemi-parkinsonian rat model of Parkinson's disease","volume":"26","author":"Perez-Bouza","year":"2017","journal-title":"Cell Transplant."},{"key":"10.1016\/j.bbrc.2018.01.020_bib13","doi-asserted-by":"crossref","first-page":"8114","DOI":"10.1073\/pnas.0711755105","article-title":"Proc. GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse","volume":"105","author":"Carnicella","year":"2008","journal-title":"Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbrc.2018.01.020_bib14","first-page":"1130","article-title":"Neurobiol. Astrocytes show reduced support of motor neurons with aging that is accelerated in a rodent model of ALS","volume":"36","author":"Das","year":"2015","journal-title":"Aging"},{"key":"10.1016\/j.bbrc.2018.01.020_bib15","article-title":"Regulation and effects of neurotrophic factors after neural stem cell transplantation in a transgenic mouse model of Alzheimer disease","author":"Li","year":"2017","journal-title":"J.\u00a0Neurosci. Res."},{"key":"10.1016\/j.bbrc.2018.01.020_bib16","first-page":"199","article-title":"Effects of adipose-derived mesenchymal stem cells over-expressing glial cell line-derived neurotrophic factor on electrically injured sciatic nerve of rats","volume":"31","author":"Chen","year":"2015","journal-title":"Zhonghua Shaoshang Zazhi"},{"key":"10.1016\/j.bbrc.2018.01.020_bib17","article-title":"Vitamin D regulation of GDNF\/Ret signaling in dopaminergic neurons","author":"RAN","year":"2017","journal-title":"Faseb. J."},{"key":"10.1016\/j.bbrc.2018.01.020_bib18","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nprot.2008.214","article-title":"Immunodesign of experimental sepsis by cecal ligation and puncture","volume":"4","author":"Rittirsch","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbrc.2018.01.020_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.archger.2016.02.005","article-title":"Advanced age enhances the sepsis-induced up-regulation of the \u03b3- and \u03b17-nicotinic acetylcholine receptors in different parts of the skeletal muscles","volume":"65","author":"Xie","year":"2016","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/j.bbrc.2018.01.020_bib20","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1002\/mus.21284","article-title":"Noninvasive model of sciatic nerve conduction in healthy and septic mice: reliability and normative data","volume":"40","author":"Osuchowski","year":"2009","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.bbrc.2018.01.020_bib21","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/mus.20022","article-title":"Electrodiagnostic criteria for acute and chronic inflammatory demyelinating polyradiculoneuropathy","volume":"29","author":"Van den Bergh","year":"2004","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.bbrc.2018.01.020_bib22","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.jss.2015.09.012","article-title":"Sepsis induced denervation-like changes at the neuromuscular junction","volume":"200","author":"Liu","year":"2016","journal-title":"J.\u00a0Surg. Res."},{"key":"10.1016\/j.bbrc.2018.01.020_bib23","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1016\/j.febslet.2015.11.006","article-title":"GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease","volume":"589","author":"Kramer","year":"2015","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbrc.2018.01.020_bib24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.neuroscience.2016.07.040","article-title":"Electrical muscle stimulation elevates intramuscular BDNF and GDNF mRNA following peripheral nerve injury and repair in rats","volume":"334","author":"Willand","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbrc.2018.01.020_bib25","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/S0014-4886(03)00183-3","article-title":"Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor sustain the axonal regeneration of chronically axotomized motoneurons in\u00a0vivo","volume":"183","author":"Boyd","year":"2003","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbrc.2018.01.020_bib26","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1046\/j.1460-9568.2002.01891.x","article-title":"A\u00a0dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor","volume":"15","author":"Boyd","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbrc.2018.01.020_bib27","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/ar.22404","article-title":"Expression of glial cell line-derived neurotrophic factor and its receptors in cultured retinal M\u00fcller cells under high glucose circumstance","volume":"295","author":"Zhu","year":"2012","journal-title":"Anat. Rec."},{"key":"10.1016\/j.bbrc.2018.01.020_bib28","doi-asserted-by":"crossref","first-page":"12656","DOI":"10.3390\/ijms131012656","article-title":"Relation between pro-inflammatory cytokines and acetylcholine levels in relapsing-remitting multiple sclerosis patients","volume":"13","author":"Reale","year":"2012","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2018.01.020_bib29","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/nrn812","article-title":"The GDNF family: signalling, biological functions and therapeutic value","volume":"3","author":"Airaksinen","year":"2002","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbrc.2018.01.020_bib30","doi-asserted-by":"crossref","first-page":"39159","DOI":"10.1074\/jbc.M006908200","article-title":"Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase","volume":"275","author":"Besset","year":"2000","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2018.01.020_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176166","article-title":"Zebrafish GDNF and its co-receptor GFR\u03b11 activate the human RET receptor and promote the survival of dopaminergic neurons in\u00a0vitro","volume":"12","author":"Saarenp\u00e4\u00e4","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2018.01.020_bib32","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1042\/CS20050161","article-title":"Clinical relevance of the neurotrophins and their receptors","volume":"110","author":"Allen","year":"2006","journal-title":"Clin. Sci."},{"key":"10.1016\/j.bbrc.2018.01.020_bib33","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0896-6273(00)80453-5","article-title":"Persephin, a novel neurotrophic factor related to GDNF and neurturin","volume":"20","author":"Milbrandt","year":"1998","journal-title":"Neuron"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X18300202?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X18300202?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T11:16:03Z","timestamp":1574939763000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X18300202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S0006291X18300202"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.01.020","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Glial cell-derived neurotrophic factor alleviates sepsis-induced neuromuscular dysfunction by decreasing the expression of \u03b3- and \u03b17-nicotinic acetylcholine receptors in an experimental rat model of neuromyopathy","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.01.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}