{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T15:25:38Z","timestamp":1781796338573,"version":"3.54.5"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"The Fifth People's Hospital of Shanghai Foundation","award":["2015WYQJ02"],"award-info":[{"award-number":["2015WYQJ02"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.bbrc.2018.01.096","type":"journal-article","created":{"date-parts":[[2018,1,17]],"date-time":"2018-01-17T02:14:36Z","timestamp":1516155276000},"page":"679-685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["NMR-based serum metabolomics study reveals a innovative diagnostic model for missed abortion"],"prefix":"10.1016","volume":"496","author":[{"given":"Zhenghong","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyi","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhua","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Fei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2018.01.096_bib1","first-page":"151","article-title":"Missed abortion and application of misoprostol","volume":"64","author":"Zeqiri","year":"2010","journal-title":"Med. Arh."},{"issue":"3","key":"10.1016\/j.bbrc.2018.01.096_bib2","first-page":"195","article-title":"Epidemiology analysis of high risk factors for 1945 cases of missed abortion","volume":"36","author":"Hua-fen","year":"2016","journal-title":"Reproduction and Contraception"},{"issue":"6","key":"10.1016\/j.bbrc.2018.01.096_bib3","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1097\/SHK.0000000000000056","article-title":"Diagnostic potential of endotoxin scattering photometry for sepsis and septic shock[J]","volume":"40","author":"Shimizu","year":"2013","journal-title":"Shock"},{"issue":"9","key":"10.1016\/j.bbrc.2018.01.096_bib4","first-page":"1894","article-title":"A\u00a0pilot study on association between phthalate exposure and missed miscarriage","volume":"20","author":"Yi","year":"2016","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"5","key":"10.1016\/j.bbrc.2018.01.096_bib5","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.3349\/ymj.2016.57.5.1271","article-title":"Prevalence and antibiotic susceptibility of mycoplasma hominis and ureaplasma urealyticum in pregnant women","volume":"57","author":"Lee","year":"2016","journal-title":"Yonsei Med. J."},{"key":"10.1016\/j.bbrc.2018.01.096_bib6","first-page":"2179","article-title":"Changes in reactive oxygen species, superoxide dismutase, and hypoxia-inducible factor-1alpha levels in missed abortion","volume":"7","author":"Zhu","year":"2014","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.bbrc.2018.01.096_bib7","first-page":"1069","article-title":"Clinical features of missed abortion","volume":"72","author":"Baszak","year":"2001","journal-title":"Ginekol. Pol."},{"key":"10.1016\/j.bbrc.2018.01.096_bib8","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1155\/2013\/969473","article-title":"Activin a and follistatin as biomarkers for ectopic pregnancy and missed abortion","volume":"35","author":"Daponte","year":"2013","journal-title":"Dis. Markers"},{"key":"10.1016\/j.bbrc.2018.01.096_bib9","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.clinbiochem.2014.03.013","article-title":"Placental growth factor, soluble fms-like tyrosine kinase 1 and progesterone as diagnostic biomarkers for ectopic pregnancy and missed abortion","volume":"47","author":"Martinez-Ruiz","year":"2014","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.bbrc.2018.01.096_bib10","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/msb4100153","article-title":"A\u00a0top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model","volume":"3","author":"Martin","year":"2007","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.bbrc.2018.01.096_bib11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-1258-2_1","article-title":"Overview of mass spectrometry-based metabolomics: opportunities and challenges","volume":"1198","author":"Gowda","year":"2013","journal-title":"Meth. Mol. Biol."},{"key":"10.1016\/j.bbrc.2018.01.096_bib12","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1080\/004982599238047","article-title":"'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data","volume":"29","author":"Nicholson","year":"1999","journal-title":"Xenobiotica"},{"key":"10.1016\/j.bbrc.2018.01.096_bib13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1023\/A:1013713905833","article-title":"Metabolomics\u2013the link between genotypes and phenotypes","volume":"48","author":"Fiehn","year":"2002","journal-title":"Plant Mol. Biol."},{"key":"10.1016\/j.bbrc.2018.01.096_bib14","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-1258-2_1","article-title":"Overview of mass spectrometry-based metabolomics: opportunities and challenges","volume":"1198","author":"Gowda","year":"2014","journal-title":"Meth. Mol. Biol."},{"key":"10.1016\/j.bbrc.2018.01.096_bib15","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1161\/HYPERTENSIONAHA.113.00588","article-title":"Recent advances in the understanding of the pathophysiology of preeclampsia","volume":"62","author":"Warrington","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.bbrc.2018.01.096_bib16","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.placenta.2010.07.002","article-title":"Changes in the metabolic footprint of placental explant-conditioned medium cultured in different oxygen tensions from placentas of small for gestational age and normal pregnancies","volume":"31","author":"Horgan","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.bbrc.2018.01.096_bib17","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.clinbiochem.2012.04.012","article-title":"Lipid fingerprinting in women with early-onset preeclampsia: a first look","volume":"45","author":"Oliveira","year":"2012","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.bbrc.2018.01.096_bib18","series-title":"Methods Of Prediction And Prevention Of Pre-Eclampsia: systematic Reviews Of Accuracy And Effectiveness Literature With Economic Modelling. NIHR Evaluation","author":"Meads","year":"2008"},{"key":"10.1016\/j.bbrc.2018.01.096_bib19","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1530\/jrf.0.0890269","article-title":"Glucose, glutamine and inorganic phosphate in early development of the pig embryo in\u00a0vitro","volume":"89","author":"Petters","year":"1990","journal-title":"J.\u00a0Reprod. Fertil."},{"key":"10.1016\/j.bbrc.2018.01.096_bib20","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0014-5793(91)80347-6","article-title":"DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems","volume":"281","author":"Halliwell","year":"1991","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbrc.2018.01.096_bib21","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1095\/biolreprod.103.025742","article-title":"Effect of inhibiting nitric oxide production on mouse preimplantation embryo development and metabolism","volume":"71","author":"Manser","year":"2004","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.bbrc.2018.01.096_bib22","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1093\/humrep\/17.4.999","article-title":"Non-invasive amino acid turnover predicts human embryo developmental capacity","volume":"17","author":"Houghton","year":"2002","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.bbrc.2018.01.096_bib23","doi-asserted-by":"crossref","first-page":"404S","DOI":"10.1042\/bst025404s","article-title":"Glutamine as a possible precursor of l-arginine and thus nitric oxide synthesis in murine macrophages","volume":"25","author":"Murphy","year":"1997","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbrc.2018.01.096_bib24","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1017\/S0967199407004273","article-title":"Glutamine and hypotaurine improves intracellular oxidative status and in\u00a0vitro development of porcine preimplantation embryos","volume":"15","author":"Suzuki","year":"2007","journal-title":"Zygote"},{"key":"10.1016\/j.bbrc.2018.01.096_bib25","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0899-9007(00)00474-3","article-title":"Oral glutamine: does it make sense?","volume":"17","author":"Roth","year":"2001","journal-title":"Nutrition"},{"key":"10.1016\/j.bbrc.2018.01.096_bib26","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1006\/mgme.1999.2857","article-title":"Glutamine, as a precursor of glutathione, and oxidative stress","volume":"67","author":"Amores-S\u00e1nchez","year":"1999","journal-title":"Mol. Genet. Metabol."},{"key":"10.1016\/j.bbrc.2018.01.096_bib27","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1071\/RD06032","article-title":"Effects of amino acid supplements and replacement of polyvinyl alcohol with bovine serum albumin in porcine zygote medium","volume":"18","author":"Suzuki","year":"2006","journal-title":"Reprod. Fertil. Dev."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X18301116?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X18301116?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T16:17:06Z","timestamp":1574957826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X18301116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S0006291X18301116"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.01.096","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NMR-based serum metabolomics study reveals a innovative diagnostic model for missed abortion","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.01.096","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}