{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:09:09Z","timestamp":1792098549158,"version":"4.4.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Nature Science Foundations of China","doi-asserted-by":"publisher","award":["31400767"],"award-info":[{"award-number":["31400767"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Nature Science Foundations of China","doi-asserted-by":"publisher","award":["31370936"],"award-info":[{"award-number":["31370936"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Beijing Natural Science Foundation","doi-asserted-by":"publisher","award":["7154182"],"award-info":[{"award-number":["7154182"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.bbrc.2018.09.030","type":"journal-article","created":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T02:02:45Z","timestamp":1536631365000},"page":"679-685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Depleting the carboxy-terminus of human Wnt5a attenuates collagen-induced arthritis in DBA\/1 mice"],"prefix":"10.1016","volume":"504","author":[{"given":"Wei","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menglin","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxuan","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiyang","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunpeng","family":"Dou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihui","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenming","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2018.09.030_bib1","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nature01661","article-title":"Evolving concepts of rheumatoid arthritis","volume":"423","author":"Firestein","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2018.09.030_bib2","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/S0140-6736(10)60826-4","article-title":"Rheumatoid arthritis","volume":"376","author":"Scott","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.bbrc.2018.09.030_bib3","first-page":"368","article-title":"One year in review 2017: pathogenesis of rheumatoid arthritis","volume":"35","author":"Angelotti","year":"2017","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.bbrc.2018.09.030_bib4","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s13075-017-1305-1","article-title":"Differences in serum and synovial CD4+ T cells and cytokine profiles to stratify patients with inflammatory osteoarthritis and rheumatoid arthritis","volume":"19","author":"Penatti","year":"2017","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbrc.2018.09.030_bib5","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s13000-015-0309-x","article-title":"MicroRNA-26b inhibits cell proliferation and cytokine secretion in human RASF cells via the Wnt\/GSK-3 beta\/beta-catenin pathway","volume":"10","author":"Sun","year":"2015","journal-title":"Diagn. Pathol."},{"key":"10.1016\/j.bbrc.2018.09.030_bib6","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nm.2653","article-title":"Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis","volume":"18","author":"Maeda","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2018.09.030_bib7","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1002\/jcp.25687","article-title":"Role of Wnt5a in the pathogenesis of inflammatory diseases","volume":"232","author":"Pashirzad","year":"2017","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.bbrc.2018.09.030_bib8","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1359\/jbmr.080901","article-title":"Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice","volume":"24","author":"Zhu","year":"2009","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.bbrc.2018.09.030_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jb\/mvw071","article-title":"Differences in the secretion and transport of Wnt proteins","volume":"161","author":"Takada","year":"2017","journal-title":"J.\u00a0Biochem."},{"key":"10.1016\/j.bbrc.2018.09.030_bib10","doi-asserted-by":"crossref","first-page":"15436","DOI":"10.1073\/pnas.0704747104","article-title":"Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation","volume":"104","author":"Nemeth","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbrc.2018.09.030_bib11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1126\/science.1222879","article-title":"Structural basis of Wnt recognition by frizzled","volume":"337","author":"Janda","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2018.09.030_bib12","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.str.2013.05.006","article-title":"Structural Studies of Wnts and identification of an LRP6 binding site","volume":"21","author":"Chu","year":"2013","journal-title":"Structure"},{"key":"10.1016\/j.bbrc.2018.09.030_bib13","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1002\/adhm.201600668","article-title":"A\u00a0truncated IL-17RC peptide ameliorates synovitis and bone destruction of arthritic mice","volume":"5","author":"Du","year":"2016","journal-title":"Adv. Health Mater."},{"key":"10.1016\/j.bbrc.2018.09.030_bib14","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1136\/annrheumdis-2013-203371","article-title":"Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis","volume":"74","author":"Ramos","year":"2015","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbrc.2018.09.030_bib15","doi-asserted-by":"crossref","first-page":"5128","DOI":"10.1016\/j.vaccine.2008.03.060","article-title":"Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus","volume":"26","author":"Muthumani","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.bbrc.2018.09.030_bib16","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.intimp.2014.03.017","article-title":"A\u00a0monoclonal antibody ameliorates local inflammation and osteoporosis by targeting TNF-alpha and RANKL","volume":"20","author":"Qian","year":"2014","journal-title":"Int. Immunopharm."},{"key":"10.1016\/j.bbrc.2018.09.030_bib17","doi-asserted-by":"crossref","first-page":"840","DOI":"10.7150\/ijms.19268","article-title":"The simultaneous inhibitory effect of niclosamide on RANKL-induced osteoclast formation and osteoblast differentiation","volume":"14","author":"Liu","year":"2017","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.bbrc.2018.09.030_bib18","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1046\/j.1523-1747.2001.01276.x","article-title":"Treatment of peripheral blood mononuclear cells with 8-methoxypsoralen plus ultraviolet A radiation induces a shift in cytokine expression from a Th1 to a Th2 response","volume":"116","author":"Klosner","year":"2001","journal-title":"J.\u00a0Invest. Dermatol."},{"key":"10.1016\/j.bbrc.2018.09.030_bib19","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s00424-017-1952-8","article-title":"Latest perspectives on macrophages in bone homeostasis","volume":"469","author":"Bozec","year":"2017","journal-title":"Pfl\u00fcgers Archiv"},{"key":"10.1016\/j.bbrc.2018.09.030_bib20","article-title":"The plasticity of Th17 cells in the pathogenesis of rheumatoid arthritis","volume":"6","author":"Kotake","year":"2017","journal-title":"J.\u00a0Clin. Med."},{"key":"10.1016\/j.bbrc.2018.09.030_bib21","first-page":"32","article-title":"The role of Th1 and Th17 cells in glomerulonephritis","volume":"4","author":"Azadegan-Dehkordi","year":"2015","journal-title":"J.\u00a0Nephropathol."},{"key":"10.1016\/j.bbrc.2018.09.030_bib22","doi-asserted-by":"crossref","first-page":"751793","DOI":"10.1155\/2015\/751793","article-title":"Altered immunoregulation in rheumatoid arthritis: the role of regulatory T cells and proinflammatory Th17 cells and therapeutic implications","volume":"2015","author":"Alunno","year":"2015","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.bbrc.2018.09.030_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0054630","article-title":"Prediction of structure of human WNT-CRD (FZD) complex for computational drug repurposing","volume":"8","author":"Ain","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2018.09.030_bib24","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1038\/nprot.2012.085","article-title":"Template-based protein structure modeling using the RaptorX web server","volume":"7","author":"Kallberg","year":"2012","journal-title":"Nat. Protoc."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X1831948X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X1831948X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T14:25:05Z","timestamp":1538403905000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X1831948X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0006291X1831948X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.09.030","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Depleting the carboxy-terminus of human Wnt5a attenuates collagen-induced arthritis in DBA\/1 mice","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.09.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}