{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:06:10Z","timestamp":1783721170395,"version":"3.55.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T00:00:00Z","timestamp":1572393600000},"content-version":"am","delay-in-days":363,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"MEXT of Japan","award":["17H06417"],"award-info":[{"award-number":["17H06417"]}]},{"name":"Japan AMED","award":["JP17gm0910005j0003"],"award-info":[{"award-number":["JP17gm0910005j0003"]}]},{"DOI":"10.13039\/501100001691","name":"JSPS of Japan","doi-asserted-by":"publisher","award":["18K06649"],"award-info":[{"award-number":["18K06649"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01 AI073770"],"award-info":[{"award-number":["R01 AI073770"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01 AI122747"],"award-info":[{"award-number":["R01 AI122747"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R21 AI105561"],"award-info":[{"award-number":["R21 AI105561"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.bbrc.2018.09.168","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T10:25:56Z","timestamp":1539080756000},"page":"1070-1076","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Both the N- and C- terminal regions of the Chlamydial inclusion protein D (IncD) are required for interaction with the pleckstrin homology domain of the ceramide transport protein CERT"],"prefix":"10.1016","volume":"505","author":[{"given":"Keigo","family":"Kumagai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cherilyn A.","family":"Elwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Ando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne N.","family":"Engel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Hanada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2018.09.168_bib1","series-title":"Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases","author":"Mandell","year":"2010"},{"key":"10.1016\/j.bbrc.2018.09.168_bib2","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nrmicro.2016.30","article-title":"Chlamydia cell biology and pathogenesis","volume":"14","author":"Elwell","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib3","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1002\/j.1460-2075.1996.tb00433.x","article-title":"Chlamydia trachomatis interrupts an exocytic pathway to acquire endogenously synthesized sphingomyelin in transit from the Golgi apparatus to the plasma membrane","volume":"15","author":"Hackstadt","year":"1996","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2018.09.168_bib4","article-title":"Inclusion biogenesis and reactivation of persistent Chlamydia trachomatis requires host cell sphingolipid biosynthesis","volume":"5","author":"Kesley Robertson","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2018.09.168_bib5","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1046\/j.1462-5822.2000.00077.x","article-title":"Host cell-derived sphingolipids are required for the intracellular growth of Chlamydia trachomatis","volume":"2","author":"Van Ooij","year":"2000","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002198","article-title":"Chlamydia trachomatis co-opts gbf1 and cert to acquire host sphingomyelin for distinct roles during intracellular development","volume":"7","author":"Elwell","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2018.09.168_bib7","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/nature02188","article-title":"Molecular machinery for non-vesicular trafficking of ceramide","volume":"426","author":"Hanada","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2018.09.168_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002092","article-title":"The lipid transfer protein CERT interacts with the Chlamydia inclusion protein IncD and participates to ER-Chlamydia inclusion membrane contact sites","volume":"7","author":"Derr\u00e9","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2018.09.168_bib9","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1128\/JB.01290-13","article-title":"Expression and targeting of secreted proteins from Chlamydia trachomatis","volume":"196","author":"Bauler","year":"2014","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib10","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1128\/IAI.01530-14","article-title":"Expression of the effector protein IncD in Chlamydia trachomatis mediates recruitment of the lipid transfer protein CERT and the endoplasmic reticulum-resident protein VAPB to the inclusion membrane","volume":"82","author":"Agaisse","year":"2014","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbrc.2018.09.168_bib11","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.12752","article-title":"The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake","volume":"19","author":"Koch-Edelmann","year":"2017","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib12","doi-asserted-by":"crossref","first-page":"30279","DOI":"10.1074\/jbc.M605032200","article-title":"Efficient trafficking of ceramide from the endoplasmic reticulum to the golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT","volume":"281","author":"Kawano","year":"2006","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2018.09.168_bib13","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.RA118.002465","article-title":"Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif","author":"Sugiki","year":"2018","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2018.09.168_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fcimb.2015.00013","article-title":"Characterization of interactions between inclusion membrane proteins from Chlamydia trachomatis","volume":"5","author":"Gauliard","year":"2015","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fcimb.2017.00079","article-title":"A\u00a0Co-infection model system and the use of chimeric proteins to study Chlamydia inclusion proteins interaction","volume":"7","author":"Han","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib16","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1006\/jmbi.2002.5416","article-title":"Oligomeric state of membrane transport proteins analyzed with blue native electrophoresis and analytical ultracentrifugation","volume":"317","author":"Heuberger","year":"2002","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0088124","article-title":"Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs","volume":"9","author":"Yamaji","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.bbrc.2018.09.168_bib18","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1128\/IAI.00917-13","article-title":"New frontiers in type III secretion biology: the Chlamydia perspective","volume":"82","author":"Mueller","year":"2014","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbrc.2018.09.168_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.22709","article-title":"Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction","volume":"6","author":"Elwell","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.bbrc.2018.09.168_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.22311","article-title":"Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis","volume":"6","author":"Paul","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.bbrc.2018.09.168_bib21","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1128\/JB.00933-15","article-title":"A\u00a0functional core of IncA is required for Chlamydia trachomatis inclusion fusion","volume":"198","author":"Weber","year":"2016","journal-title":"J.\u00a0Bacteriol."},{"key":"10.1016\/j.bbrc.2018.09.168_bib22","doi-asserted-by":"crossref","first-page":"33469","DOI":"10.1074\/jbc.M114.592063","article-title":"An \u03b1-helical core encodes the dual functions of the chlamydial protein IncA","volume":"289","author":"Ronzone","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2018.09.168_bib23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.bbrc.2015.04.116","article-title":"Chlamydia trachomatis inclusion membrane protein CT850 interacts with the dynein light chain DYNLT1 (Tctex1)","volume":"462","author":"Mital","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2018.09.168_bib24","doi-asserted-by":"crossref","first-page":"16682","DOI":"10.1074\/jbc.M800799200","article-title":"Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation","volume":"283","author":"Charruyer","year":"2008","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2018.09.168_bib25","doi-asserted-by":"crossref","first-page":"10748","DOI":"10.1074\/jbc.M113.528380","article-title":"Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells","volume":"289","author":"Kumagai","year":"2014","journal-title":"J.\u00a0Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X18321077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X18321077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T11:28:30Z","timestamp":1757762910000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X18321077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S0006291X18321077"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.09.168","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Both the N- and C- terminal regions of the Chlamydial inclusion protein D (IncD) are required for interaction with the pleckstrin homology domain of the ceramide transport protein CERT","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2018.09.168","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}