{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T18:53:41Z","timestamp":1758048821305,"version":"3.44.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,22]],"date-time":"2020-03-22T00:00:00Z","timestamp":1584835200000},"content-version":"am","delay-in-days":356,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"ANR","doi-asserted-by":"publisher","award":["FIFA2-12-BSV1-0010"],"award-info":[{"award-number":["FIFA2-12-BSV1-0010"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"ANR","doi-asserted-by":"publisher","award":["MITOXDRUGS-DS0403"],"award-info":[{"award-number":["MITOXDRUGS-DS0403"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Association d'Aide aux Jeunes Infirmes"},{"name":"Association contre les Maladies Mitochondriales"},{"name":"Association Fran\u00e7aise contre l'Ataxie de Friedreich"},{"name":"Ouvrir Les Yeux"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.bbrc.2019.02.033","type":"journal-article","created":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T10:08:25Z","timestamp":1551262105000},"page":"658-664","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Distinctive Krebs cycle remodeling in iPSC-derived neural and mesenchymal stem cells"],"prefix":"10.1016","volume":"511","author":[{"given":"Sarah","family":"Benlamara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laetitia","family":"Aubry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Fabregue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paule","family":"B\u00e9nit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Rustin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malgorzata","family":"Rak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.bbrc.2019.02.033_bib1","doi-asserted-by":"crossref","first-page":"e20914","DOI":"10.1371\/journal.pone.0020914","article-title":"Energy metabolism in human pluripotent stem cells and their differentiated counterparts","volume":"6","author":"Varum","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2019.02.033_bib2","doi-asserted-by":"crossref","first-page":"4860","DOI":"10.1038\/emboj.2011.401","article-title":"UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells","volume":"30","author":"Zhang","year":"2011","journal-title":"EMBO J."},{"key":"10.1016\/j.bbrc.2019.02.033_bib3","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1387\/ijdb.103198ap","article-title":"Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in\u00a0vitro and in\u00a0vivo differentiation of human ES and iPS cells","volume":"54","author":"Prigione","year":"2010","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.bbrc.2019.02.033_bib4","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.stem.2016.08.008","article-title":"Glycolytic metabolism plays a functional role in regulating human pluripotent stem cell state","volume":"19","author":"Gu","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.bbrc.2019.02.033_bib5","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.cmet.2015.02.002","article-title":"Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells","volume":"21","author":"Moussaieff","year":"2015","journal-title":"Cell Metabol."},{"key":"10.1016\/j.bbrc.2019.02.033_bib6","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.stem.2017.08.018","article-title":"MYC controls human pluripotent stem cell fate decisions through regulation of metabolic flux","volume":"21","author":"Cliff","year":"2017","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.bbrc.2019.02.033_bib7","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.bbabio.2014.03.013","article-title":"Unsuspected task for an old team: succinate, fumarate and other Krebs cycle acids in metabolic remodeling","volume":"1837","author":"B\u00e9nit","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbrc.2019.02.033_bib8","doi-asserted-by":"crossref","first-page":"20160100","DOI":"10.1098\/rsfs.2016.0100","article-title":"Mitochondrial metabolites: undercover signalling molecules","volume":"7","author":"Frezza","year":"2017","journal-title":"Interf. Focus"},{"key":"10.1016\/j.bbrc.2019.02.033_bib9","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nature13981","article-title":"Intracellular \u03b1-ketoglutarate maintains the pluripotency of embryonic stem cells","volume":"518","author":"Carey","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2019.02.033_bib10","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.cmet.2016.07.002","article-title":"\u03b1-Ketoglutarate accelerates the initial differentiation of primed human pluripotent stem cells","volume":"24","author":"TeSlaa","year":"2016","journal-title":"Cell Metabol."},{"key":"10.1016\/j.bbrc.2019.02.033_bib11","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1126\/science.1172482","article-title":"Human induced pluripotent stem cells free of vector and transgene sequences","volume":"324","author":"Yu","year":"2009","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.bbrc.2019.02.033_bib12","doi-asserted-by":"crossref","first-page":"e294","DOI":"10.1038\/tp.2013.71","article-title":"Differentiation from human pluripotent stem cells of cortical neurons of the superficial layers amenable to psychiatric disease modeling and high-throughput drug screening","volume":"20","author":"Boissart","year":"2013","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.bbrc.2019.02.033_bib13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1152\/physiolgenomics.00077.2010","article-title":"Combined mRNA and microRNA profiling reveals that miR-148a and miR-20b control human mesenchymal stem cell phenotype via EPAS1","volume":"43","author":"Giraud-Triboult","year":"2011","journal-title":"Physiol. Genom."},{"key":"10.1016\/j.bbrc.2019.02.033_bib14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0009-8981(94)90055-8","article-title":"Biochemical and molecular investigations in respiratory chain deficiencies","volume":"228","author":"Rustin","year":"1994","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.bbrc.2019.02.033_bib15","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cca.2006.05.034","article-title":"Three spectrophotometric assays for the measurement of the five respiratory chain complexes in minuscule biological samples","volume":"374","author":"B\u00e9nit","year":"2006","journal-title":"Clin. Chim. Acta"},{"issue":"5","key":"10.1016\/j.bbrc.2019.02.033_bib16","first-page":"11","article-title":"Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples","volume":"28","author":"Goncalves","year":"2010","journal-title":"BMC Biochem."},{"key":"10.1016\/j.bbrc.2019.02.033_bib17","article-title":"An effective, versatile, and inexpensive device for oxygen uptake measurement","volume":"6","author":"B\u00e9nit","year":"2017","journal-title":"J.\u00a0Clin. Med."},{"key":"10.1016\/j.bbrc.2019.02.033_bib18","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2019.02.033_bib19","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1089\/clo.2005.7.141","article-title":"The expression of mitochondrial DNA transcription factors during early cardiomyocyte in\u00a0vitro differentiation from human embryonic stem cells","volume":"7","author":"St John","year":"2005","journal-title":"Clon Stem Cells"},{"key":"10.1016\/j.bbrc.2019.02.033_bib20","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.cmet.2011.06.011","article-title":"Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming","volume":"14","author":"Folmes","year":"2011","journal-title":"Cell Metabol."},{"key":"10.1016\/j.bbrc.2019.02.033_bib21","doi-asserted-by":"crossref","first-page":"27414","DOI":"10.1016\/S0021-9258(18)47001-9","article-title":"Tricarboxylic acid cycle in rat brain synaptosomes. Fluxes and interactions with aspartate aminotransferase and malate\/aspartate shuttle","volume":"269","author":"Yudkoff","year":"1994","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2019.02.033_bib22","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.cmet.2016.03.001","article-title":"Glutamine oxidation is indispensable for survival of human pluripotent stem cells","volume":"23","author":"Tohyama","year":"2016","journal-title":"Cell Metabol."},{"key":"10.1016\/j.bbrc.2019.02.033_bib23","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/stem.590","article-title":"Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells","volume":"29","author":"Mandal","year":"2011","journal-title":"Stem Cell."},{"key":"10.1016\/j.bbrc.2019.02.033_bib24","first-page":"000831","article-title":"The role of \u03b1-ketoglutarate-dependent proteins in pluripotency acquisition and maintenance","author":"Tran","year":"2018","journal-title":"J.\u00a0Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X19302207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X19302207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T11:33:11Z","timestamp":1757763191000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X19302207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S0006291X19302207"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2019.02.033","relation":{},"ISSN":["0006-291X"],"issn-type":[{"type":"print","value":"0006-291X"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinctive Krebs cycle remodeling in iPSC-derived neural and mesenchymal stem cells","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2019.02.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}