{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:41:03Z","timestamp":1777473663242,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18fk0108049"],"award-info":[{"award-number":["JP18fk0108049"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18kk0205011"],"award-info":[{"award-number":["JP18kk0205011"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18jk0210002"],"award-info":[{"award-number":["JP18jk0210002"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18fk0410011"],"award-info":[{"award-number":["JP18fk0410011"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18fk0410022"],"award-info":[{"award-number":["JP18fk0410022"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP17fm0208017"],"award-info":[{"award-number":["JP17fm0208017"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18fk0410003"],"award-info":[{"award-number":["JP18fk0410003"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["18K07157"],"award-info":[{"award-number":["18K07157"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["88000500"],"award-info":[{"award-number":["88000500"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["18H02666"],"award-info":[{"award-number":["18H02666"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.bbrc.2019.03.003","type":"journal-article","created":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T23:39:21Z","timestamp":1552520361000},"page":"213-217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["CD8+ T cell-based strong selective pressure on multiple simian immunodeficiency virus targets in macaques possessing a protective MHC class I haplotype"],"prefix":"10.1016","volume":"512","author":[{"given":"Trang Thi Thu","family":"Hau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Midori","family":"Nakamura-Hoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Kanno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takushi","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Nishizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayuri","family":"Seki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Kawana-Tachikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William W.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan Anh","family":"Nguyen Thi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3096-6749","authenticated-orcid":false,"given":"Tetsuro","family":"Matano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2019.03.003_bib1","doi-asserted-by":"crossref","first-page":"4650","DOI":"10.1128\/jvi.68.7.4650-4655.1994","article-title":"Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome","volume":"68","author":"Koup","year":"1994","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.bbrc.2019.03.003_bib2","doi-asserted-by":"crossref","first-page":"6103","DOI":"10.1128\/jvi.68.9.6103-6110.1994","article-title":"Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection","volume":"68","author":"Borrow","year":"1994","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.bbrc.2019.03.003_bib3","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1128\/JVI.72.1.164-169.1998","article-title":"Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian\/human immunodeficiency virus during primary infections of rhesus macaques","volume":"72","author":"Matano","year":"1998","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.bbrc.2019.03.003_bib4","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1084\/jem.189.6.991","article-title":"Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques","volume":"189","author":"Jin","year":"1999","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.bbrc.2019.03.003_bib5","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1126\/science.283.5403.857","article-title":"Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes","volume":"283","author":"Schmitz","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2019.03.003_bib6","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1126\/science.283.5408.1748","article-title":"HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage","volume":"283","author":"Carrington","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2019.03.003_bib7","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/nm0502-493","article-title":"Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection","volume":"8","author":"O'Connor","year":"2002","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2019.03.003_bib8","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/nri2357","article-title":"Impact of MHC class I diversity on immune control of immunodeficiency virus replication","volume":"8","author":"Goulder","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbrc.2019.03.003_bib9","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1084\/jem.20040432","article-title":"Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial","volume":"199","author":"Matano","year":"2004","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.bbrc.2019.03.003_bib10","doi-asserted-by":"crossref","first-page":"6481","DOI":"10.1128\/JVI.07077-11","article-title":"Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in Burmese rhesus macaques","volume":"86","author":"Nomura","year":"2012","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.bbrc.2019.03.003_bib11","article-title":"A\u00a0novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques","volume":"8","author":"Takahashi","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2019.03.003_bib12","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1128\/JVI.02634-13","article-title":"Control of simian immunodeficiency virus replication by vaccine-induced Gag- and Vif-specific CD8+ T cells","volume":"88","author":"Iwamoto","year":"2014","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.bbrc.2019.03.003_bib13","doi-asserted-by":"crossref","first-page":"6276","DOI":"10.1128\/JVI.00557-16","article-title":"Biphasic CD8+ T-cell defense in simian immunodeficiency virus control by acute-phase passive neutralizing antibody immunization","volume":"90","author":"Iseda","year":"2016","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.bbrc.2019.03.003_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0000540","article-title":"Post-infection immunodeficiency virus control by neutralizing antibodies","volume":"2","author":"Yamamoto","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2019.03.003_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073453","article-title":"Limited impact of passive non-neutralizing antibody immunization in acute SIV infection on viremia control in rhesus macaques","volume":"8","author":"Nakane","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2019.03.003_bib16","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s00251-010-0462-z","article-title":"Diversity of MHC class I genes in Burmese-origin rhesus macaques","volume":"62","author":"Naruse","year":"2010","journal-title":"Immunogenetics"},{"key":"10.1016\/j.bbrc.2019.03.003_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005247","article-title":"Broadening of virus-specific CD8+ T-cell responses is indicative of residual viral replication in aviremic SIV controllers","volume":"11","author":"Nomura","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2019.03.003_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006638","article-title":"In\u00a0vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts","volume":"13","author":"Seki","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2019.03.003_bib19","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/nm1520","article-title":"CD8+ T-cell responses to different HIV proteins have discordant associations with viral load","volume":"13","author":"Kiepiela","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2019.03.003_bib20","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1128\/JVI.01596-09","article-title":"Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic","volume":"84","author":"Vojnov","year":"2010","journal-title":"J.\u00a0Virol."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X19303742?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X19303742?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:22:30Z","timestamp":1777382550000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X19303742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S0006291X19303742"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2019.03.003","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CD8+ T cell-based strong selective pressure on multiple simian immunodeficiency virus targets in macaques possessing a protective MHC class I haplotype","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2019.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}