{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T21:31:31Z","timestamp":1772573491510,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.bbrc.2019.05.080","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T10:07:14Z","timestamp":1559902034000},"page":"644-650","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Long non-coding RNA CASC9 enhances breast cancer progression by promoting metastasis through the meditation of miR-215\/TWIST2 signaling associated with TGF-\u03b2 expression"],"prefix":"10.1016","volume":"515","author":[{"given":"Jing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhicheng","family":"Quan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.bbrc.2019.05.080_bib1","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/ijc.30716","article-title":"Worldwide burden of cancer attributable to HPV by site, country and HPV type","volume":"141","author":"de Martel","year":"2017","journal-title":"Int. J. Cancer"},{"issue":"5","key":"10.1016\/j.bbrc.2019.05.080_bib2","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/IGC.0b013e3181dc827e","article-title":"Phase 1 study of tirapazamine in combination with radiation and weekly cisplatin in patients with locally advanced cervical cancer","volume":"20","author":"Rischin","year":"2010","journal-title":"Int. J. Gynecol. Cancer"},{"issue":"14","key":"10.1016\/j.bbrc.2019.05.080_bib3","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1200\/JCO.2014.58.9093","article-title":"Complete regression of metastatic cervical cancer after treatment with human papillomavirus\u2013targeted tumor-infiltrating T cells","volume":"33","author":"Stevanovi\u0107","year":"2015","journal-title":"J.\u00a0Clin. Oncol."},{"issue":"4","key":"10.1016\/j.bbrc.2019.05.080_bib4","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ccell.2016.03.010","article-title":"Long noncoding RNAs in cancer pathways","volume":"29","author":"Schmitt","year":"2016","journal-title":"Cancer Cell"},{"issue":"41","key":"10.1016\/j.bbrc.2019.05.080_bib5","doi-asserted-by":"crossref","first-page":"5661","DOI":"10.1038\/onc.2017.184","article-title":"LncRNA-mediated regulation of cell signaling in cancer","volume":"36","author":"Peng","year":"2017","journal-title":"Oncogene"},{"issue":"6","key":"10.1016\/j.bbrc.2019.05.080_bib6","doi-asserted-by":"crossref","first-page":"703","DOI":"10.4161\/rna.20481","article-title":"The hallmarks of cancer: a long non-coding RNA point of view","volume":"9","author":"Gutschner","year":"2012","journal-title":"RNA Biol."},{"issue":"1","key":"10.1016\/j.bbrc.2019.05.080_bib7","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1080\/15384047.2015.1108496","article-title":"Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21","volume":"17","author":"Zhang","year":"2016","journal-title":"Cancer Biol. Ther."},{"issue":"2","key":"10.1016\/j.bbrc.2019.05.080_bib8","doi-asserted-by":"crossref","first-page":"521","DOI":"10.3892\/ijo.2014.2758","article-title":"Long non-coding RNA HOTAIR is associated with human cervical cancer progression","volume":"46","author":"Kim","year":"2015","journal-title":"Int. J. Oncol."},{"issue":"9","key":"10.1016\/j.bbrc.2019.05.080_bib9","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1002\/cam4.770","article-title":"The long noncoding RNA CASC9 regulates migration and invasion in esophageal cancer","volume":"5","author":"Pan","year":"2016","journal-title":"Cancer medicine"},{"issue":"12","key":"10.1016\/j.bbrc.2019.05.080_bib10","doi-asserted-by":"crossref","first-page":"6338","DOI":"10.1111\/jcmm.13932","article-title":"Long noncoding RNA CASC9\/miR-519d\/STAT3 positive feedback loop facilitate the glioma tumourigenesis","volume":"22","author":"Liu","year":"2018","journal-title":"J.\u00a0Cell Mol. Med."},{"issue":"12","key":"10.1016\/j.bbrc.2019.05.080_bib11","doi-asserted-by":"crossref","first-page":"19592","DOI":"10.18632\/oncotarget.14752","article-title":"Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer","volume":"8","author":"Donnarumma","year":"2017","journal-title":"Oncotarget"},{"issue":"66","key":"10.1016\/j.bbrc.2019.05.080_bib12","doi-asserted-by":"crossref","first-page":"53240","DOI":"10.1039\/C5RA08958A","article-title":"Limitations of MTT and CCK-8 assay for evaluation of graphene cytotoxicity","volume":"5","author":"Jiao","year":"2015","journal-title":"RSC Adv."},{"key":"10.1016\/j.bbrc.2019.05.080_bib13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.redox.2018.09.017","article-title":"Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine","volume":"20","author":"Kong","year":"2019","journal-title":"Redox biology"},{"key":"10.1016\/j.bbrc.2019.05.080_bib14","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.redox.2018.10.003","article-title":"Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation","volume":"20","author":"Ugun-Klusek","year":"2019","journal-title":"Redox biology"},{"issue":"17","key":"10.1016\/j.bbrc.2019.05.080_bib15","doi-asserted-by":"crossref","first-page":"4994","DOI":"10.1158\/0008-5472.CAN-15-2322","article-title":"TMEM2 is a SOX4-regulated gene that mediates metastatic migration and invasion in breast cancer","volume":"76","author":"Lee","year":"2016","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.bbrc.2019.05.080_bib16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/15476286.2017.1391441","article-title":"Comparing two approaches of miR-34a target identification, biotinylated-miRNA pulldown vs miRNA overexpression","volume":"15","author":"Awan","year":"2018","journal-title":"RNA Biol."},{"issue":"4","key":"10.1016\/j.bbrc.2019.05.080_bib17","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.3390\/cancers7040902","article-title":"Cancer-associated fibroblasts: their characteristics and their roles in tumor growth","volume":"7","author":"Shiga","year":"2015","journal-title":"Cancers"},{"issue":"1","key":"10.1016\/j.bbrc.2019.05.080_bib18","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.canlet.2016.05.022","article-title":"Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-\u03b2 pathways","volume":"379","author":"Liu","year":"2016","journal-title":"Cancer Lett."},{"issue":"5","key":"10.1016\/j.bbrc.2019.05.080_bib19","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1089\/dna.2016.3615","article-title":"The long noncoding RNA cancer susceptibility candidate 9 promotes nasopharyngeal carcinogenesis via stabilizing HIF1\u03b1","volume":"36","author":"Su","year":"2017","journal-title":"DNA Cell Biol."},{"issue":"5","key":"10.1016\/j.bbrc.2019.05.080_bib20","first-page":"1665","article-title":"lncRNA CASC9 positively regulates CHK1 to promote breast cancer cell proliferation and survival through sponging the miR-195\/497 cluster","volume":"54","author":"Shao","year":"2019","journal-title":"Int. J. Oncol."},{"issue":"4","key":"10.1016\/j.bbrc.2019.05.080_bib21","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.cell.2018.01.028","article-title":"A\u00a0subset of cancer-associated fibroblasts determines therapy resistance","volume":"172","author":"Huelsken","year":"2018","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.bbrc.2019.05.080_bib22","first-page":"1146","article-title":"Fibroblast ER\u03b1 promotes bladder cancer invasion via increasing the CCL1 and IL-6 signals in the tumor microenvironment","volume":"5","author":"Yeh","year":"2015","journal-title":"American journal of cancer research"},{"issue":"10","key":"10.1016\/j.bbrc.2019.05.080_bib23","doi-asserted-by":"crossref","first-page":"5396","DOI":"10.1074\/jbc.M115.713123","article-title":"Loss of \u03b1-tubulin acetylation is associated with TGF-\u03b2-induced epithelial-mesenchymal transition","volume":"291","author":"Gu","year":"2016","journal-title":"J.\u00a0Biol. Chem."},{"issue":"1","key":"10.1016\/j.bbrc.2019.05.080_bib24","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s12094-014-1194-6","article-title":"MiR-215\/192 participates in gastric cancer progression","volume":"17","author":"Xu","year":"2015","journal-title":"Clin. Transl. Oncol."},{"key":"10.1016\/j.bbrc.2019.05.080_bib25","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.canlet.2019.02.030","article-title":"Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity","volume":"450","author":"Ullmann","year":"2019","journal-title":"Cancer Lett."},{"issue":"11","key":"10.1016\/j.bbrc.2019.05.080_bib26","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1038\/bjc.2011.401","article-title":"miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215","volume":"105","author":"White","year":"2011","journal-title":"Br. J. Canc."},{"issue":"47","key":"10.1016\/j.bbrc.2019.05.080_bib27","doi-asserted-by":"crossref","first-page":"4707","DOI":"10.1038\/onc.2011.181","article-title":"Twist2 contributes to breast cancer progression by promoting an epithelial\u2013mesenchymal transition and cancer stem-like cell self-renewal","volume":"30","author":"Fang","year":"2011","journal-title":"Oncogene"},{"issue":"11","key":"10.1016\/j.bbrc.2019.05.080_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078200","article-title":"The role of nuclear \u03b2-catenin accumulation in the Twist2-induced ovarian cancer EMT","volume":"8","author":"Mao","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bbrc.2019.05.080_bib29","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1186\/1479-5876-11-275","article-title":"Down-regulation of miR-138 promotes colorectal cancer metastasis via directly targeting TWIST2","volume":"11","author":"Long","year":"2013","journal-title":"J.\u00a0Transl. Med."},{"issue":"12","key":"10.1016\/j.bbrc.2019.05.080_bib30","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1038\/s41419-017-0077-5","article-title":"MicroRNA-221-3p, a TWIST2 target, promotes cervical cancer metastasis by directly targeting THBS2","volume":"8","author":"Wei","year":"2017","journal-title":"Cell Death Dis."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X19309568?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X19309568?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,22]],"date-time":"2019-06-22T08:14:05Z","timestamp":1561191245000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X19309568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S0006291X19309568"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2019.05.080","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long non-coding RNA CASC9 enhances breast cancer progression by promoting metastasis through the meditation of miR-215\/TWIST2 signaling associated with TGF-\u03b2 expression","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2019.05.080","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}