{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T09:17:14Z","timestamp":1773307034172,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004735","name":"Hunan Provincial Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007292","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007292","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.bbrc.2020.01.130","type":"journal-article","created":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T07:57:48Z","timestamp":1580457468000},"page":"549-554","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Gemcitabine inhibits cisplatin resistance in cisplatin-resistant A549 cells by upregulating trx-interacting protein and inducing cell cycle arrest"],"prefix":"10.1016","volume":"524","author":[{"given":"Wenjie","family":"Cao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhijun","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojuan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingming","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2020.01.130_bib1","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/cncr.31551","article-title":"Annual report to the nation on the status of cancer, part I: national cancer statistics","volume":"124","author":"Cronin","year":"2018","journal-title":"Cancer"},{"key":"10.1016\/j.bbrc.2020.01.130_bib2","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"Ca - Cancer J. Clin."},{"key":"10.1016\/j.bbrc.2020.01.130_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/17425255.2018.1416095","article-title":"Pharmacogenetics of platinum-based chemotherapy in non-small cell lung cancer: predictive validity of polymorphisms of ERCC1","volume":"14","author":"Hamilton","year":"2018","journal-title":"Expet Opin. Drug Metabol. Toxicol."},{"key":"10.1016\/j.bbrc.2020.01.130_bib4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/978-3-319-24932-2_11","article-title":"Personalized therapy of non-small cell lung cancer (NSCLC)","volume":"890","author":"Gadgeel","year":"2016","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.bbrc.2020.01.130_bib5","doi-asserted-by":"crossref","first-page":"181","DOI":"10.4081\/monaldi.2005.618","article-title":"Cytotoxic chemotherapy in advanced non-small cell lung cancer","volume":"63","author":"Scagliotti","year":"2005","journal-title":"Monaldi Arch. Chest Dis."},{"key":"10.1016\/j.bbrc.2020.01.130_bib6","doi-asserted-by":"crossref","first-page":"102925","DOI":"10.1016\/j.bioorg.2019.102925","article-title":"Cisplatin: the first metal based anticancer drug","volume":"88","author":"Ghosh","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bbrc.2020.01.130_bib7","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1101\/gad.1897010","article-title":"Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer","volume":"24","author":"Oliver","year":"2010","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbrc.2020.01.130_bib8","doi-asserted-by":"crossref","first-page":"39001","DOI":"10.1038\/srep39001","article-title":"MiR-150 promotes cellular metastasis in non-small cell lung cancer by targeting FOXO4","volume":"6","author":"Li","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2020.01.130_bib9","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1038\/s41388-018-0534-3","article-title":"Oncogenic microRNA-411 promotes lung carcinogenesis by directly targeting suppressor genes SPRY4 and TXNIP","volume":"38","author":"Zhang","year":"2019","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2020.01.130_bib10","first-page":"1292","article-title":"Additive antitumour effect of Dallose in combination with cisplatin in non-small cell lung cancer cells","volume":"39","author":"Kanaji","year":"2018","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.bbrc.2020.01.130_bib11","first-page":"377","article-title":"Rare sugar D-allose induces specific up-regulation of TXNIP and subsequent G1 cell cycle arrest in hepatocellular carcinoma cells by stabilization of p27kip1","volume":"32","author":"Yamaguchi","year":"2008","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.bbrc.2020.01.130_bib12","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1002\/2211-5463.12518","article-title":"Both Ser361 phosphorylation and the C-arrestin domain of thioredoxin interacting protein are important for cell cycle blockade at the G1\/S checkpoint","volume":"8","author":"Kamitori","year":"2018","journal-title":"FEBS Open Bio."},{"key":"10.1016\/j.bbrc.2020.01.130_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0082241","article-title":"Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer","volume":"8","author":"Gyorffy","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.bbrc.2020.01.130_bib14","doi-asserted-by":"crossref","first-page":"38027","DOI":"10.1074\/jbc.M111.275503","article-title":"MondoA senses non-glucose sugars: regulation of thioredoxin-interacting protein (TXNIP) and the hexose transport curb","volume":"286","author":"Stoltzman","year":"2011","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2020.01.130_bib15","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/jnci\/djk196","article-title":"Cisplatin- versus carboplatin-based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: an individual patient data meta-analysis","volume":"99","author":"Ardizzoni","year":"2007","journal-title":"J.\u00a0Natl. Cancer Inst."},{"key":"10.1016\/j.bbrc.2020.01.130_bib16","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-3-319-40389-2_6","article-title":"Chemotherapy for advanced non-small cell lung cancer","volume":"170","author":"Dietrich","year":"2016","journal-title":"Canc. Treat Res."},{"key":"10.1016\/j.bbrc.2020.01.130_bib17","first-page":"3819","article-title":"Gemcitabine and cisplatin for treatment of lung cancer in\u00a0vitro and vivo","volume":"22","author":"Teng","year":"2018","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.bbrc.2020.01.130_bib18","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.cell.2018.04.012","article-title":"An acquired vulnerability of drug-resistant Melanoma with therapeutic potential","volume":"173","author":"Wang","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2020.01.130_bib19","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0065-230X(08)60984-7","article-title":"Cross resistance and collateral sensitivity studies in cancer chemotherapy","volume":"7","author":"Hutchison","year":"1963","journal-title":"Adv. Canc. Res."},{"key":"10.1016\/j.bbrc.2020.01.130_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0181081","article-title":"Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G2\/M cell cycle arrest","volume":"12","author":"Sarin","year":"2017","journal-title":"PloS One"},{"key":"10.1016\/j.bbrc.2020.01.130_bib21","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00280-019-03869-4","article-title":"The role of thioredoxin system in cancer: strategy for cancer therapy","volume":"84","author":"Jia","year":"2019","journal-title":"Canc. Chemother. Pharmacol."},{"key":"10.1016\/j.bbrc.2020.01.130_bib22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1620\/tjem.238.131","article-title":"D-allose inhibits cancer cell growth by reducing GLUT1 expression","volume":"238","author":"Noguchi","year":"2016","journal-title":"Tohoku J. Exp. Med."},{"key":"10.1016\/j.bbrc.2020.01.130_bib23","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.phrs.2016.01.001","article-title":"Cisplatin resistance and opportunities for precision medicine","volume":"106","author":"Amable","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bbrc.2020.01.130_bib24","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1002\/1873-3468.13156","article-title":"Enhanced expression of thioredoxin-interacting-protein regulates oxidative DNA damage and aging","volume":"592","author":"Oberacker","year":"2018","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbrc.2020.01.130_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.critrevonc.2010.10.009","article-title":"Lessons from the comparison of two randomized clinical trials using gemcitabine and cisplatin for advanced biliary tract cancer","volume":"80","author":"Furuse","year":"2011","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.bbrc.2020.01.130_bib26","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1056\/NEJMoa0908721","article-title":"Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer","volume":"362","author":"Valle","year":"2010","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.bbrc.2020.01.130_bib27","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/hed.20310","article-title":"Phase II study of gemcitabine plus vinorelbine in the treatment of cisplatin-resistant nasopharyngeal carcinoma","volume":"28","author":"Wang","year":"2006","journal-title":"Head Neck"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X20302138?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X20302138?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T11:49:15Z","timestamp":1757764155000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X20302138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S0006291X20302138"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2020.01.130","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gemcitabine inhibits cisplatin resistance in cisplatin-resistant A549 cells by upregulating trx-interacting protein and inducing cell cycle arrest","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2020.01.130","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}