{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:12:56Z","timestamp":1790356376642,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770278"],"award-info":[{"award-number":["81770278"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770422"],"award-info":[{"award-number":["81770422"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81921001"],"award-info":[{"award-number":["81921001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970424"],"award-info":[{"award-number":["81970424"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7171010"],"award-info":[{"award-number":["7171010"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7182168"],"award-info":[{"award-number":["7182168"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7191012"],"award-info":[{"award-number":["7191012"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.bbrc.2020.02.013","type":"journal-article","created":{"date-parts":[[2020,2,10]],"date-time":"2020-02-10T12:42:30Z","timestamp":1581338550000},"page":"916-922","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Macrophage-derived sulfur dioxide is a novel inflammation regulator"],"prefix":"10.1016","volume":"524","author":[{"given":"Zhigang","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoshu","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfang","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junbao","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2020.02.013_bib1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00424-017-1950-x","article-title":"The role of macrophages in hypertension and its complications","volume":"469","author":"Justin Rucker","year":"2017","journal-title":"Pfl\u00fcgers Archiv"},{"key":"10.1016\/j.bbrc.2020.02.013_bib2","article-title":"Transcriptional and epigenetic regulation of macrophages in atherosclerosis","author":"Kuznetsova","year":"2019","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.bbrc.2020.02.013_bib3","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1161\/CIRCULATIONAHA.115.020754","article-title":"Genetic and pharmacologic inhibition of the chemokine receptor CXCR2 prevents experimental hypertension and vascular dysfunction","volume":"134","author":"Wang","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2020.02.013_bib4","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1093\/cvr\/cvn120","article-title":"Cytokines and atherosclerosis: a comprehensive review of studies in mice","volume":"79","author":"Kleemann","year":"2008","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbrc.2020.02.013_bib5","doi-asserted-by":"crossref","first-page":"4925","DOI":"10.1210\/en.2014-1595","article-title":"Inhibiting DNA methylation by 5-Aza-2\u2019-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation","volume":"155","author":"Cao","year":"2014","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbrc.2020.02.013_bib6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.yjmcc.2019.01.009","article-title":"DNA methyltransferase 1 and Kruppel-like factor 4 axis regulates macrophage inflammation and atherosclerosis","volume":"128","author":"Tang","year":"2019","journal-title":"J.\u00a0Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbrc.2020.02.013_bib7","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3389\/fimmu.2019.00705","article-title":"NF-kappaB signaling in macrophages: dynamics, crosstalk, and signal integration","volume":"10","author":"Dorrington","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbrc.2020.02.013_bib8","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.4049\/jimmunol.1601515","article-title":"Akt signaling pathway in macrophage activation and M1\/M2 polarization","volume":"198","author":"Vergadi","year":"2017","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.bbrc.2020.02.013_bib9","doi-asserted-by":"crossref","first-page":"10610","DOI":"10.18632\/aging.102480","article-title":"Ets2 suppresses inflammatory cytokines through MAPK\/NF-kappaB signaling and directly binds to the IL-6 promoter in macrophages","volume":"11","author":"Ma","year":"2019","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.bbrc.2020.02.013_bib10","doi-asserted-by":"crossref","first-page":"8961951","DOI":"10.1155\/2016\/8961951","article-title":"Endogenous sulfur dioxide: a new member of gasotransmitter family in the cardiovascular system","author":"Huang","year":"2016","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.bbrc.2020.02.013_bib11","doi-asserted-by":"crossref","first-page":"10465","DOI":"10.3390\/ijms140510465","article-title":"The role of sulfur dioxide in the regulation of mitochondrion-related cardiomyocyte apoptosis in rats with isopropylarterenol-induced myocardial injury","volume":"14","author":"Jin","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2020.02.013_bib12","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/j.1745-7254.2008.00864.x","article-title":"Effects of endogenous sulfur dioxide on monocrotaline-induced pulmonary hypertension in rats","volume":"29","author":"Jin","year":"2008","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.bbrc.2020.02.013_bib13","doi-asserted-by":"crossref","first-page":"882","DOI":"10.3389\/fimmu.2018.00882","article-title":"The increased endogenous sulfur dioxide acts as a compensatory mechanism for the downregulated endogenous hydrogen sulfide pathway in the endothelial cell inflammation","volume":"9","author":"Zhang","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbrc.2020.02.013_bib14","doi-asserted-by":"crossref","first-page":"27026","DOI":"10.1038\/srep27026","article-title":"Endogenous sulfur dioxide is a novel adipocyte-derived inflammatory inhibitor","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2020.02.013_bib15","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1042\/CS20170274","article-title":"Sulphur dioxide suppresses inflammatory response by sulphenylating NF-kappa B p65 at Cys(38) in a rat model of acute lung injury","volume":"131","author":"Chen","year":"2017","journal-title":"Clin. Sci."},{"key":"10.1016\/j.bbrc.2020.02.013_bib16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/jbt.21492","article-title":"Role of sulfur dioxide in acute lung injury following limb ischemia\/reperfusion in rats","volume":"27","author":"Huang","year":"2013","journal-title":"J.\u00a0Biochem. Mol. Toxicol."},{"key":"10.1016\/j.bbrc.2020.02.013_bib17","doi-asserted-by":"crossref","first-page":"9741","DOI":"10.1074\/jbc.M113.517995","article-title":"Hydrogen sulfide suppresses oxidized low-density lipoprotein (ox-LDL)-stimulated monocyte chemoattractant protein 1 generation from macrophages via the nuclear factor kappaB (NF-kappaB) pathway","volume":"289","author":"Du","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.bbrc.2020.02.013_bib18","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1039\/C3CC46468G","article-title":"A\u00a0water-soluble near-infrared probe for colorimetric and ratiometric sensing of SO2 derivatives in living cells","volume":"50","author":"Wu","year":"2014","journal-title":"Chem Commun (Camb)"},{"key":"10.1016\/j.bbrc.2020.02.013_bib19","article-title":"Sulfur dioxide protects against collagen accumulation in pulmonary artery in association with downregulation of the transforming growth factor beta 1\/Smad pathway in pulmonary hypertensive rats","volume":"5","author":"Yu","year":"2016","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.bbrc.2020.02.013_bib20","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.2174\/1389557511009011039","article-title":"Sulfur dioxide: a novel gaseous signal in the regulation of cardiovascular functions","volume":"10","author":"Liu","year":"2010","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.bbrc.2020.02.013_bib21","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1745-7254.2008.00845.x","article-title":"Endogenously generated sulfur dioxide and its vasorelaxant effect in rats","volume":"29","author":"Du","year":"2008","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.bbrc.2020.02.013_bib22","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.bbrc.2011.10.012","article-title":"Endogenous generation of sulfur dioxide in rat tissues","volume":"415","author":"Luo","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2020.02.013_bib23","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.ijcard.2016.09.111","article-title":"Downregulated endogenous sulfur dioxide\/aspartate aminotransferase pathway is involved in angiotensin II-stimulated cardiomyocyte autophagy and myocardial hypertrophy in mice","volume":"225","author":"Chen","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbrc.2020.02.013_bib24","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.4103\/0366-6999.235875","article-title":"Inhibitory effects of sulfur dioxide on rat myocardial fibroblast proliferation and migration","volume":"131","author":"Zhang","year":"2018","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.bbrc.2020.02.013_bib25","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1161\/CIRCULATIONAHA.116.021884","article-title":"Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap","volume":"134","author":"Shah","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2020.02.013_bib26","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/cvr\/cvt258","article-title":"Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation","volume":"101","author":"Wang","year":"2014","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbrc.2020.02.013_bib27","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/cr.2009.137","article-title":"The nuclear signaling of NF-kappaB: current knowledge, new insights, and future perspectives","volume":"20","author":"Wan","year":"2010","journal-title":"Cell Res."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X20302734?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X20302734?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T01:28:13Z","timestamp":1730338093000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X20302734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S0006291X20302734"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2020.02.013","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Macrophage-derived sulfur dioxide is a novel inflammation regulator","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2020.02.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}