{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:51:03Z","timestamp":1776693063330,"version":"3.51.2"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.bbrc.2020.05.111","type":"journal-article","created":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T08:09:00Z","timestamp":1591344540000},"page":"35-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Osteoclastic miR-301-b knockout reduces ovariectomy (OVX)-induced bone loss by regulating CYDR\/NF-\u03baB signaling pathway"],"prefix":"10.1016","volume":"529","author":[{"given":"Jungao","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haisheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huashun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2020.05.111_bib1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.cytogfr.2020.02.003","article-title":"The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis","volume":"52","author":"Li","year":"2020","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.bbrc.2020.05.111_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/humrep\/dez259","article-title":"Age at natural menopause and development of chronic conditions and multimorbidity: results from an Australian prospective cohort","volume":"35","author":"Xu","year":"2020","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.bbrc.2020.05.111_bib3","doi-asserted-by":"crossref","first-page":"16069","DOI":"10.1038\/nrdp.2016.69","article-title":"Postmenopausal osteoporosis","volume":"2","author":"Eastell","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.bbrc.2020.05.111_bib4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ecl.2016.11.001","article-title":"Novel therapies for postmenopausal osteoporosis","volume":"46","author":"Bandeira","year":"2017","journal-title":"Endocrinol Metab. Clin. N. Am."},{"key":"10.1016\/j.bbrc.2020.05.111_bib5","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.3389\/fphar.2019.01587","article-title":"Vindoline inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice","volume":"10","author":"Zhan","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbrc.2020.05.111_bib6","doi-asserted-by":"crossref","first-page":"110067","DOI":"10.1016\/j.biopha.2020.110067","article-title":"Shikonin mitigates ovariectomy-induced bone loss and RANKL-induced osteoclastogenesis via TRAF6-mediated signaling pathways","volume":"126","author":"Chen","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbrc.2020.05.111_bib7","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41580-018-0045-7","article-title":"Regulation of microRNA function in animals","volume":"20","author":"Gebert","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.bbrc.2020.05.111_bib8","doi-asserted-by":"crossref","first-page":"1901412","DOI":"10.1002\/advs.201901412","article-title":"The miR-193a-3p-MAP3k3 signaling Axis regulates substrate topography-induced osteogenesis of bone marrow stem cells","volume":"7","author":"Lv","year":"2020","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bbrc.2020.05.111_bib9","doi-asserted-by":"crossref","first-page":"5348","DOI":"10.1096\/fj.201902463RR","article-title":"miR-136-3p targets PTEN to regulate vascularization and bone formation and ameliorates alcohol-induced osteopenia","volume":"34","author":"Chen","year":"2020","journal-title":"Faseb. J."},{"key":"10.1016\/j.bbrc.2020.05.111_bib10","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1080\/15384101.2020.1731053","article-title":"Down-regulated microRNA-141 facilitates osteoblast activity and inhibits osteoclast activity to ameliorate osteonecrosis of the femoral head via up-regulating TGF-\u03b22","volume":"19","author":"Tian","year":"2020","journal-title":"Cell Cycle"},{"key":"10.1016\/j.bbrc.2020.05.111_bib11","doi-asserted-by":"crossref","first-page":"725","DOI":"10.3892\/ijo.2014.2243","article-title":"MicroRNA-301b promotes cell invasiveness through targeting TP63 in pancreatic carcinoma cells","volume":"44","author":"Funamizu","year":"2014","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.bbrc.2020.05.111_bib12","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.bbrc.2019.04.138","article-title":"Exosomal miR-301 derived from mesenchymal stem cells protects myocardial infarction by inhibiting myocardial autophagy","volume":"514","author":"Li","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2020.05.111_bib13","doi-asserted-by":"crossref","first-page":"16132","DOI":"10.1038\/nmicrobiol.2016.132","article-title":"Pseudomonas aeruginosa infection augments inflammation through miR-301b repression of c-Myb-mediated immune activation and infiltration","volume":"1","author":"Li","year":"2016","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.bbrc.2020.05.111_bib14","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/s41419-019-1522-4","article-title":"Overexpression of microRNA-301b accelerates hippocampal microglia activation and cognitive impairment in mice with depressive-like behavior through the NF-\u03baB signaling pathway","volume":"10","author":"Tang","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbrc.2020.05.111_bib15","doi-asserted-by":"crossref","first-page":"12794","DOI":"10.1038\/ncomms12794","article-title":"GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation","volume":"7","author":"Liu","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2020.05.111_bib16","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.7150\/ijbs.12296","article-title":"Triterpenoid saponin W3 from anemone flaccida suppresses osteoclast differentiation through inhibiting activation of MAPKs and NF-\u03baB pathways","volume":"11","author":"Kong","year":"2015","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.bbrc.2020.05.111_bib17","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.bone.2018.11.013","article-title":"miRNA-seq analysis of human vertebrae provides insight into the mechanism underlying GIOP","volume":"120","author":"Ren","year":"2019","journal-title":"Bone"},{"key":"10.1016\/j.bbrc.2020.05.111_bib18","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1002\/jbmr.3059","article-title":"BMI-1 mediates estrogen-deficiency-induced bone loss by inhibiting reactive oxygen species accumulation and T cell activation","volume":"32","author":"Li","year":"2017","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.bbrc.2020.05.111_bib19","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12943-017-0625-8","article-title":"miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1","volume":"16","author":"Liu","year":"2017","journal-title":"Mol. Canc."},{"key":"10.1016\/j.bbrc.2020.05.111_bib20","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/21691401.2019.1699820","article-title":"CYLD expression in dendritic cells involved in the immunoregulation of pulmonary adenocarcinoma via NF-\u03baB pathway","volume":"48","author":"Yu","year":"2020","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"key":"10.1016\/j.bbrc.2020.05.111_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008474","article-title":"PARP1-cGAS-NF-\u03baB pathway of proinflammatory macrophage activation by extracellular vesicles released during Trypanosoma cruzi infection and Chagas disease","volume":"16","author":"Choudhuri","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2020.05.111_bib22","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1161\/CIRCRESAHA.116.310262","article-title":"Human alternative macrophages populate calcified areas of atherosclerotic lesions and display impaired RANKL-induced osteoclastic bone resorption activity","volume":"121","author":"Chinetti-Gbaguidi","year":"2017","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbrc.2020.05.111_bib23","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1172\/JCI39650","article-title":"Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL\/M-CSF signaling and osteoclast polarization","volume":"120","author":"Ito","year":"2010","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.bbrc.2020.05.111_bib24","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1182\/blood.2019000889","article-title":"EBV microRNA-BHRF1-2-5p targets the 3\u2019UTR of immune checkpoint ligands PD-L1 and PD-L2","volume":"134","author":"Cristino","year":"2019","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2020.05.111_bib25","first-page":"239","article-title":"Biogenesis of mammalian microRNAs: a global view","volume":"10","author":"Graves","year":"2012","journal-title":"Dev. Reprod. Biol."},{"key":"10.1016\/j.bbrc.2020.05.111_bib26","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2020.05.111_bib27","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.actbio.2019.12.022","article-title":"Bioactive iron oxide nanoparticles suppress osteoclastogenesis and ovariectomy-induced bone loss through regulating the TRAF6-p62-CYLD signaling complex","volume":"103","author":"Liu","year":"2020","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bbrc.2020.05.111_bib28","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1172\/JCI34257","article-title":"Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice","volume":"118","author":"Jin","year":"2008","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.bbrc.2020.05.111_bib29","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1142\/S0192415X08006326","article-title":"Electroacupuncture promotes insulin-like growth factors system in ovariectomized osteoporosis rats","volume":"36","author":"Feng","year":"2008","journal-title":"Am. J. Chin. Med."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X20310330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X20310330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T11:52:58Z","timestamp":1757764378000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X20310330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["S0006291X20310330"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2020.05.111","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Osteoclastic miR-301-b knockout reduces ovariectomy (OVX)-induced bone loss by regulating CYDR\/NF-\u03baB signaling pathway","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2020.05.111","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}