{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T21:03:11Z","timestamp":1789765391018,"version":"4.0.1"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"am","delay-in-days":329,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009031","name":"Japan Agency for Medical Research and Development Department of Industrial Academic Collaboration","doi-asserted-by":"publisher","award":["JP19fk0108104"],"award-info":[{"award-number":["JP19fk0108104"]}],"id":[{"id":"10.13039\/501100009031","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.bbrc.2021.08.048","type":"journal-article","created":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T10:47:47Z","timestamp":1629715667000},"page":"36-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Strong alkaline electrolyzed water efficiently inactivates SARS-CoV-2, other viruses, and Gram-negative bacteria"],"prefix":"10.1016","volume":"575","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3554-0755","authenticated-orcid":false,"given":"Youichi","family":"Suzuki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Hishiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akino","family":"Emi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3650-1221","authenticated-orcid":false,"given":"Shoichi","family":"Sakaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronko","family":"Itamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rain","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamio","family":"Matsuzawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunitada","family":"Shimotohno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Mizokami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2021.08.048_bib1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1365-2672.2001.01364.x","article-title":"Spread and prevention of some common viral infections in community facilities and domestic homes","volume":"91","author":"Barker","year":"2001","journal-title":"J.\u00a0Appl. Microbiol."},{"key":"10.1016\/j.bbrc.2021.08.048_bib2","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/S0140-6736(13)60222-6","article-title":"Global burden of childhood pneumonia and diarrhoea","volume":"381","author":"Walker","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.bbrc.2021.08.048_bib3","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1128\/AEM.02051-06","article-title":"Significance of fomites in the spread of respiratory and enteric viral disease","volume":"73","author":"Boone","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bbrc.2021.08.048_bib4","doi-asserted-by":"crossref","first-page":"e238","DOI":"10.1016\/S1473-3099(20)30484-9","article-title":"Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics","volume":"20","author":"Petersen","year":"2020","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.bbrc.2021.08.048_bib5","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1001\/jamainternmed.2020.0994","article-title":"Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China","volume":"180","author":"Wu","year":"2020","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.bbrc.2021.08.048_bib6","doi-asserted-by":"crossref","first-page":"747","DOI":"10.3389\/fphys.2020.00747","article-title":"COVID-19 Sepsis and microcirculation dysfunction","volume":"11","author":"Colantuoni","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bbrc.2021.08.048_bib7","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1093\/jpids\/piaa037","article-title":"What's new with the old coronaviruses?","volume":"9","author":"Ogimi","year":"2020","journal-title":"J.\u00a0Pediatric. Infect. Dis. Soc."},{"key":"10.1016\/j.bbrc.2021.08.048_bib8","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.bpobgyn.2014.07.015","article-title":"Genital herpes","volume":"28","author":"Garland","year":"2014","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"key":"10.1016\/j.bbrc.2021.08.048_bib9","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.jhin.2008.04.024","article-title":"Survival of enveloped and non-enveloped viruses on surfaces compared with other micro-organisms and impact of suboptimal disinfectant exposure","volume":"69","author":"Howie","year":"2008","journal-title":"J.\u00a0Hosp. Infect."},{"key":"10.1016\/j.bbrc.2021.08.048_bib10","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0140-6736(18)31128-0","article-title":"Viral gastroenteritis","volume":"392","author":"B\u00e1nyai","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.bbrc.2021.08.048_bib11","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1128\/jcm.32.8.1970-1975.1994","article-title":"Evaluation of Biolog system for identification of some Gram-negative bacteria of clinical importance","volume":"32","author":"Holmes","year":"1994","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.bbrc.2021.08.048_bib12","first-page":"609","article-title":"Disinfection and sterilization in health care facilities: an overview and current issues","volume":"30","author":"Rutala","year":"2016","journal-title":"Infect. Dis. Clin."},{"key":"10.1016\/j.bbrc.2021.08.048_bib13","doi-asserted-by":"crossref","first-page":"304","DOI":"10.7883\/yoken.JJID.2020.061","article-title":"Development of genetic diagnostic methods for novel coronavirus 2019 (nCoV-2019) in Japan","volume":"73","author":"Shirato","year":"2020","journal-title":"Jpn. J. Infect. Dis."},{"key":"10.1016\/j.bbrc.2021.08.048_bib14","doi-asserted-by":"crossref","first-page":"631","DOI":"10.3109\/15563659509010620","article-title":"Pulmonary collapse and pneumonia due to inhalation of a waterproofing aerosol in female CD-I Mice","volume":"33","author":"Yamashita","year":"1995","journal-title":"J.\u00a0Toxicol. Clin. Toxicol."},{"key":"10.1016\/j.bbrc.2021.08.048_bib15","series-title":"Contact Dermatitis","first-page":"366","article-title":"Patch testing","author":"Wahlberg","year":"2005"},{"key":"10.1016\/j.bbrc.2021.08.048_bib16","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/s41598-020-79803-z","article-title":"A\u00a0functional interaction between GRP78 and Zika virus E protein","volume":"11","author":"Khongwichit","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2021.08.048_bib17","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.4315\/0362-028X-71.9.1934","article-title":"Electrolyzed water and its application in the food industry","volume":"71","author":"Hricova","year":"2016","journal-title":"J.\u00a0Food Protect."},{"key":"10.1016\/j.bbrc.2021.08.048_bib18","doi-asserted-by":"crossref","first-page":"19955","DOI":"10.1038\/s41598-019-56248-7","article-title":"Comparative antibacterial activities of neutral electrolyzed oxidizing water and other chlorine-based sanitizers","volume":"9","author":"Ogunniyi","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2021.08.048_bib19","doi-asserted-by":"crossref","first-page":"e00653","DOI":"10.1128\/AEM.00653-17","article-title":"Efficacy of neutral electrolyzed water for inactivation of human norovirus","volume":"83","author":"Moorman","year":"2017","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bbrc.2021.08.048_bib20","first-page":"16","article-title":"Potential of electrolyzed water for disinfection of foot-and-mouth disease virus","volume":"79","author":"N Bui","year":"2017","journal-title":"J.\u00a0Vet. Med. Sci."},{"key":"10.1016\/j.bbrc.2021.08.048_bib21","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1126\/science.694508","article-title":"Electrostatic effects in proteins","volume":"201","author":"Perutz","year":"1978","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2021.08.048_bib22","first-page":"154","article-title":"Effects of different pH-values upon tobacco mosaic virus","volume":"3","author":"Shikata","year":"1958","journal-title":"Mem. Fac. Agric. Hokkaido"},{"key":"10.1016\/j.bbrc.2021.08.048_bib23","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1099\/0022-1317-13-1-101","article-title":"Stepwise degradation of poliovirus capsid by alkaline treatment","volume":"13","author":"Katagiri","year":"1971","journal-title":"J.\u00a0Gen. Virol."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X21012250?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X21012250?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T20:14:24Z","timestamp":1789762464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X21012250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":23,"alternative-id":["S0006291X21012250"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2021.08.048","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Strong alkaline electrolyzed water efficiently inactivates SARS-CoV-2, other viruses, and Gram-negative bacteria","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2021.08.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}