{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T04:58:53Z","timestamp":1767848333333,"version":"3.49.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2017BH034"],"award-info":[{"award-number":["ZR2017BH034"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.bbrc.2022.09.058","type":"journal-article","created":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T10:46:22Z","timestamp":1663411582000},"page":"112-117","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Resveratrol alleviates salivary gland dysfunction induced by ovariectomy in rats"],"prefix":"10.1016","volume":"630","author":[{"given":"Lixian","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boyue","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muyun","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoxing","family":"Pang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2022.09.058_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111897","article-title":"Effects of oligonol on the submandibular gland in ovariectomized rats","volume":"141","author":"Kim","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbrc.2022.09.058_bib2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0140-6736(05)66519-1","article-title":"Treatment of menopausal symptoms: what shall we do now?","volume":"366","author":"Hickey","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.bbrc.2022.09.058_bib3","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.18632\/aging.203947","article-title":"Tonsil mesenchymal stem cells-derived extracellular vesicles prevent submandibular gland dysfunction in ovariectomized rats","volume":"14","author":"Kim","year":"2022","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.bbrc.2022.09.058_bib4","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3109\/09513590.2011.593668","article-title":"Unstimulated saliva 17beta-estradiol and xerostomia in menopause","volume":"28","author":"Agha-Hosseini","year":"2012","journal-title":"Gynecol. Endocrinol."},{"key":"10.1016\/j.bbrc.2022.09.058_bib5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1139\/bcb-2017-0196","article-title":"Mechanistic effect of human umbilical cord blood derived mesenchymal stem cells on the submandibular salivary gland in ovariectomized rats","volume":"96","author":"Gouda","year":"2018","journal-title":"Biochem. Cell. Biol."},{"key":"10.1016\/j.bbrc.2022.09.058_bib6","first-page":"45","article-title":"Diagnosis and management of xerostomia and hyposalivation","volume":"11","author":"Villa","year":"2015","journal-title":"Therapeut. Clin. Risk Manag."},{"key":"10.1016\/j.bbrc.2022.09.058_bib7","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1097\/GME.0000000000000187","article-title":"Resveratrol- and melatonin-abated ovariectomy and fructose diet-induced obesity and metabolic alterations in female rats","volume":"21","author":"Majumdar","year":"2014","journal-title":"Menopause"},{"key":"10.1016\/j.bbrc.2022.09.058_bib8","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1161\/hc2901.092200","article-title":"Hormone replacement therapy and cardiovascular disease: a statement for healthcare professionals from the American Heart Association","volume":"104","author":"Mosca","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.bbrc.2022.09.058_bib9","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.prp.2011.01.002","article-title":"Effect of estrogen therapy, soy isoflavones, and the combination therapy on the submandibular gland of ovariectomized rats","volume":"207","author":"Carvalho","year":"2011","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.bbrc.2022.09.058_bib10","doi-asserted-by":"crossref","first-page":"21376","DOI":"10.18632\/aging.103882","article-title":"The mechanism of submandibular gland dysfunction after menopause may be associated with the ferroptosis","volume":"12","author":"Kwon","year":"2020","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.bbrc.2022.09.058_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21176294","article-title":"Influence of resveratrol on the cardiovascular health effects of chronic kidney disease","volume":"21","author":"Song","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2022.09.058_bib12","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1080\/13510002.2019.1658376","article-title":"Resveratrol improves osteogenic differentiation of senescent bone mesenchymal stem cells through inhibiting endogenous reactive oxygen species production via AMPK activation","volume":"24","author":"Zhou","year":"2019","journal-title":"Redox Rep."},{"key":"10.1016\/j.bbrc.2022.09.058_bib13","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.2174\/1381612825666190410153307","article-title":"Preventive role of resveratrol against inflammatory cytokines and related diseases","volume":"25","author":"Rafe","year":"2019","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.bbrc.2022.09.058_bib14","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/biof.1399","article-title":"Role of resveratrol in regulation of cellular defense systems against oxidative stress","volume":"44","author":"Truong","year":"2018","journal-title":"Biofactors"},{"key":"10.1016\/j.bbrc.2022.09.058_bib15","doi-asserted-by":"crossref","first-page":"E23","DOI":"10.1002\/lary.24276","article-title":"Resveratrol attenuates radiation-induced salivary gland dysfunction in mice","volume":"123","author":"Xu","year":"2013","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bbrc.2022.09.058_bib16","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12986-017-0183-5","article-title":"Resveratrol regulates body weight in healthy and ovariectomized rats","volume":"14","author":"Sharma","year":"2017","journal-title":"Nutr. Metab."},{"key":"10.1016\/j.bbrc.2022.09.058_bib17","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.70710","article-title":"Dietary nitrate supplementation prevents radiotherapy-induced xerostomia","volume":"10","author":"Feng","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.bbrc.2022.09.058_bib18","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.bbrc.2018.02.068","article-title":"Dietary nitrate protects submandibular gland from hyposalivation in ovariectomized rats via suppressing cell apoptosis","volume":"497","author":"Xu","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2022.09.058_bib19","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.molmed.2020.03.009","article-title":"Mouth-watering results: clinical need, current approaches, and future directions for salivary gland regeneration","volume":"26","author":"Rocchi","year":"2020","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.bbrc.2022.09.058_bib20","doi-asserted-by":"crossref","first-page":"6064","DOI":"10.2174\/13816128113199990407","article-title":"Resveratrol and clinical trials: the crossroad from in\u00a0vitro studies to human evidence","volume":"19","author":"Tome-Carneiro","year":"2013","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.bbrc.2022.09.058_bib21","first-page":"203","article-title":"Study of changes in antioxidant enzymes status in diabetic post menopausal group of women suffering from cardiovascular complications","volume":"58","author":"Kumawat","year":"2012","journal-title":"Clin. Lab."},{"key":"10.1016\/j.bbrc.2022.09.058_bib22","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1007\/s11357-013-9519-x","article-title":"Effects of melatonin and dexpanthenol on antioxidant parameters when combined with estrogen treatment in ovariectomized rats","volume":"35","author":"Turgut","year":"2013","journal-title":"Age (Dordr)"},{"key":"10.1016\/j.bbrc.2022.09.058_bib23","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s11010-007-9569-4","article-title":"Amelioration of vanadium-induced testicular toxicity and adrenocortical hyperactivity by vitamin E acetate in rats","volume":"306","author":"Chandra","year":"2007","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.bbrc.2022.09.058_bib24","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1016\/S0024-3205(03)00179-6","article-title":"Oral administration of trans-resveratrol to Guinea pigs increases cardiac DT-diaphorase and catalase activities, and protects isolated atria from menadione toxicity","volume":"72","author":"Floreani","year":"2003","journal-title":"Life Sci."},{"key":"10.1016\/j.bbrc.2022.09.058_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110234","article-title":"The therapeutic effect of resveratrol: focusing on the Nrf2 signaling pathway","volume":"127","author":"Farkhondeh","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbrc.2022.09.058_bib26","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3164\/jcbn.16-31","article-title":"Resveratrol improves salivary dysfunction in a non-obese diabetic (NOD) mouse model of Sjogren's syndrome","volume":"59","author":"Inoue","year":"2016","journal-title":"J.\u00a0Clin. Biochem. Nutr."},{"key":"10.1016\/j.bbrc.2022.09.058_bib27","article-title":"ALX\/FPR2 modulates anti-inflammatory responses in mouse submandibular gland","volume":"6","author":"Wang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2022.09.058_bib28","first-page":"63","article-title":"[Intervention of yangfei Ziyin decoction on Sjogren's syndrome model mice]","volume":"36","author":"Tian","year":"2016","journal-title":"Zhongguo Zhong Xi Yi Jie He Za Zhi"},{"key":"10.1016\/j.bbrc.2022.09.058_bib29","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines8080261","article-title":"Resveratrol modulates transforming growth factor-beta (TGF-beta) signaling pathway for disease therapy: a new insight into its pharmacological activities","volume":"8","author":"Ashrafizadeh","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.bbrc.2022.09.058_bib30","article-title":"The therapeutic potential of resveratrol: a review of clinical trials","volume":"1","author":"Berman","year":"2017","journal-title":"NPJ Precis Oncol"},{"key":"10.1016\/j.bbrc.2022.09.058_bib31","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.imbio.2016.10.008","article-title":"Resveratrol improves treatment outcome and laboratory parameters in patients with Takayasu arteritis: a randomized double-blind and placebo-controlled trial","volume":"222","author":"Shi","year":"2017","journal-title":"Immunobiology"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X22013146?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X22013146?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T12:22:32Z","timestamp":1757766152000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X22013146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":31,"alternative-id":["S0006291X22013146"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2022.09.058","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Resveratrol alleviates salivary gland dysfunction induced by ovariectomy in rats","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2022.09.058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}