{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T06:42:09Z","timestamp":1773470529962,"version":"3.50.1"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014718","name":"Innovative Research Group Project of the National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772976"],"award-info":[{"award-number":["81772976"]}],"id":[{"id":"10.13039\/100014718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.bbrc.2023.07.024","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T01:58:05Z","timestamp":1689645485000},"page":"170-176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["LMO2 attenuates glycolytic metabolism and facilitates cytotoxic T-lymphocyte infiltration in the tumor environment of lung and breast cancers"],"prefix":"10.1016","volume":"675","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9777-2143","authenticated-orcid":false,"given":"Wenhao","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingying","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4407-0054","authenticated-orcid":false,"given":"Wei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2023.07.024_bib1","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1126\/science.1160809","article-title":"Understanding the Warburg effect: the metabolic requirements of cell proliferation","volume":"324","author":"Vander Heiden","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2023.07.024_bib2","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.semcancer.2022.07.004","article-title":"'Warburg effect' controls tumor growth, bacterial, viral infections and immunity - genetic deconstruction and therapeutic perspectives","volume":"86","author":"Pouyss\u00e9gur","year":"2022","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.bbrc.2023.07.024_bib3","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.cmet.2016.08.011","article-title":"LDHA-associated lactic acid production Blunts tumor Immunosurveillance by T and NK cells","volume":"24","author":"Brand","year":"2016","journal-title":"Cell Metabol."},{"key":"10.1016\/j.bbrc.2023.07.024_bib4","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0168-9525(98)01424-3","article-title":"LIM domains: multiple roles as adapters and functional modifiers in protein interactions","volume":"14","author":"Dawid","year":"1998","journal-title":"Trends Genet."},{"key":"10.1016\/j.bbrc.2023.07.024_bib5","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.150062","article-title":"LMO2 at 25 years: a paradigm of chromosomal translocation proteins","volume":"5","author":"Chambers","year":"2015","journal-title":"Open Biol."},{"key":"10.1016\/j.bbrc.2023.07.024_bib6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1365-2559.2012.04198.x","article-title":"Detection of LIM domain only 2 (LMO2) in normal human tissues and haematopoietic and non-haematopoietic tumours using a newly developed rabbit monoclonal antibody","volume":"61","author":"Agostinelli","year":"2012","journal-title":"Histopathology"},{"key":"10.1016\/j.bbrc.2023.07.024_bib7","article-title":"LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer","volume":"6","author":"Liu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2023.07.024_bib8","first-page":"695","article-title":"LMO2 enhances lamellipodia\/filopodia formation in basal-type breast cancer cells by mediating ARP3-Profilin1 interaction","volume":"23","author":"Liu","year":"2017","journal-title":"Med. Sci. Mon. Int. Med. J. Exp. Clin. Res."},{"key":"10.1016\/j.bbrc.2023.07.024_bib9","doi-asserted-by":"crossref","first-page":"9513","DOI":"10.18632\/oncotarget.13434","article-title":"LMO2 promotes tumor cell invasion and metastasis in basal-type breast cancer by altering actin cytoskeleton remodeling","volume":"8","author":"Liu","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.bbrc.2023.07.024_bib10","doi-asserted-by":"crossref","DOI":"10.12659\/MSMBR.924421","article-title":"Biochemical feature of LMO2 interactome and LMO2 function prospect","volume":"26","author":"Wang","year":"2020","journal-title":"Med. Sci. Monit. Basic Res."},{"key":"10.1016\/j.bbrc.2023.07.024_bib11","article-title":"A dissected LMO2 functional analysis and clinical relevance in brain gliomas","volume":"33","author":"Yuan","year":"2022","journal-title":"Biochem. Biophys. Rep."},{"key":"10.1016\/j.bbrc.2023.07.024_bib12","doi-asserted-by":"crossref","first-page":"4079","DOI":"10.1038\/s41388-022-02414-7","article-title":"A comprehensive analysis of LMO2 pathogenic regulatory profile during T-lineage development and leukemic transformation","volume":"41","author":"Wang","year":"2022","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2023.07.024_bib13","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abm3548","article-title":"Identification of a minority population of LMO2+ breast cancer cells that integrate into the vasculature and initiate metastasis","volume":"8","author":"Sikandar","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.bbrc.2023.07.024_bib14","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/1476-4598-12-152","article-title":"Tumor glycolysis as a target for cancer therapy: progress and prospects","volume":"12","author":"Ganapathy-Kanniappan","year":"2013","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bbrc.2023.07.024_bib15","doi-asserted-by":"crossref","first-page":"4633","DOI":"10.1038\/sj.onc.1209597","article-title":"Glycolysis inhibition for anticancer treatment","volume":"25","author":"Pelicano","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.bbrc.2023.07.024_bib16","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev-cellbio-092910-154237","article-title":"Aerobic glycolysis: meeting the metabolic requirements of cell proliferation","volume":"27","author":"Lunt","year":"2011","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.bbrc.2023.07.024_bib17","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.cmet.2018.03.008","article-title":"The science and translation of lactate shuttle theory","volume":"27","author":"Brooks","year":"2018","journal-title":"Cell Metabol."},{"key":"10.1016\/j.bbrc.2023.07.024_bib18","doi-asserted-by":"crossref","first-page":"23264","DOI":"10.1073\/pnas.1914557116","article-title":"An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma","volume":"116","author":"Wen","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X23008811?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X23008811?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T12:32:34Z","timestamp":1757766754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X23008811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":18,"alternative-id":["S0006291X23008811"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2023.07.024","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"LMO2 attenuates glycolytic metabolism and facilitates cytotoxic T-lymphocyte infiltration in the tumor environment of lung and breast cancers","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2023.07.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}