{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:40:38Z","timestamp":1790793638233,"version":"4.1.0"},"reference-count":301,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005780","name":"Chitkara University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.bbrc.2024.150218","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T16:31:35Z","timestamp":1717432295000},"page":"150218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"special_numbering":"C","title":["GABAergic implications in anxiety and related disorders"],"prefix":"10.1016","volume":"724","author":[{"given":"Indu","family":"Arora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj","family":"Mal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Arora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anushka","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6697-544X","authenticated-orcid":false,"given":"Manish","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"24","key":"10.1016\/j.bbrc.2024.150218_bib1","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1001\/jama.2022.22744","article-title":"Anxiety disorders: a review","volume":"328","author":"Szuhany","year":"2022","journal-title":"JAMA"},{"key":"10.1016\/j.bbrc.2024.150218_bib2","first-page":"165","article-title":"Anxiety disorders and GABA neurotransmission: a disturbance of modulation","volume":"11","author":"Nuss","year":"2015","journal-title":"Neuropsychiatric Dis. Treat."},{"key":"10.1016\/j.bbrc.2024.150218_bib3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/978-981-32-9705-0_19","article-title":"Current and novel psychopharmacological drugs for anxiety disorders","volume":"1191","author":"Bandelow","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.janxdis.2010.09.014","article-title":"Content and correlates of checking related to symptoms of obsessive compulsive disorder and generalized anxiety disorder","volume":"25","author":"Coleman","year":"2011","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.bbrc.2024.150218_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2020.595584","article-title":"Pharmacotherapy of anxiety disorders: current and emerging treatment options","volume":"11","author":"Garakani","year":"2020","journal-title":"Front. Psychiatr."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib6","doi-asserted-by":"crossref","first-page":"87","DOI":"10.31887\/DCNS.2017.19.2\/fthibaut","article-title":"Anxiety disorders: a review of current literature","volume":"19","author":"Thibaut","year":"2017","journal-title":"Dialogues Clin. Neurosci."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib7","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/pcn.13195","article-title":"Does cognitive behavioral therapy for anxiety disorders assist the discontinuation of benzodiazepines among patients with anxiety disorders? A systematic review and meta-analysis","volume":"75","author":"Takeshima","year":"2021","journal-title":"Psychiatr. Clin. Neurosci."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib8","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1159\/000524400","article-title":"Benzodiazepines remain important therapeutic options in psychiatric practice","volume":"91","author":"Dubovsky","year":"2022","journal-title":"Psychother. Psychosom."},{"issue":"Pt A","key":"10.1016\/j.bbrc.2024.150218_bib9","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.neuropharm.2018.01.036","article-title":"GABAA receptor: positive and negative allosteric modulators","volume":"136","author":"Olsen","year":"2018","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib10","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/j.1471-4159.2006.03913.x","article-title":"The glutamate\/GABAglutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer","volume":"98","author":"Bak","year":"2006","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib11","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s43141-021-00224-0","article-title":"GABAA receptors: structure, function, pharmacology, and related disorders","volume":"19","author":"Ghit","year":"2021","journal-title":"J. Genet. Eng. Biotechnol."},{"issue":"3\u20134","key":"10.1016\/j.bbrc.2024.150218_bib12","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s10571-005-4004-4","article-title":"Consequences of the evolution of the GABA(A) receptor gene family","volume":"25","author":"Darlison","year":"2005","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.bbrc.2024.150218_bib13","doi-asserted-by":"crossref","first-page":"603","DOI":"10.2147\/DDDT.S62912","article-title":"Altered \u03b3-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants","volume":"9","author":"Pehrson","year":"2015","journal-title":"Drug Des. Dev. Ther."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib14","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.neuint.2012.02.013","article-title":"Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control","volume":"61","author":"Rowley","year":"2012","journal-title":"Neurochem. Int."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0387-7604(00)00193-5","article-title":"CSF glutamate\/GABA concentrations in pyridoxine-dependent seizures: etiology of pyridoxine-dependent seizures and the mechanisms of pyridoxine action in seizure control","volume":"23","author":"Goto","year":"2001","journal-title":"Brain Dev."},{"key":"10.1016\/j.bbrc.2024.150218_bib16","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1113\/jphysiol.1979.sp012878","article-title":"[3H] gamma-Aminobutyric acid uptake into neuroglial cells of rat superior cervical sympathetic ganglia","volume":"293","author":"Bowery","year":"1979","journal-title":"J. Physiol."},{"issue":"2\u20133","key":"10.1016\/j.bbrc.2024.150218_bib17","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.neuropharm.2010.11.007","article-title":"An intrinsic GABAergic system in human lymphocytes","volume":"60","author":"Dionisio","year":"2011","journal-title":"Neuropharmacology"},{"issue":"1\u20132","key":"10.1016\/j.bbrc.2024.150218_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.autneu.2005.11.002","article-title":"The peripheral GABAergic system as a target in endocrine disorders","volume":"124","author":"Gladkevich","year":"2006","journal-title":"Auton. Neurosci. Basic Clin."},{"issue":"8","key":"10.1016\/j.bbrc.2024.150218_bib19","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.tips.2018.04.003","article-title":"An emerging circuit pharmacology of GABAA receptors","volume":"39","author":"Engin","year":"2018","journal-title":"Trends Pharmacol. Sci."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib20","doi-asserted-by":"crossref","first-page":"999","DOI":"10.3390\/molecules25040999","article-title":"Allosteric GABAA receptor modulators-A review on the most recent heterocyclic chemotypes and their synthetic accessibility","volume":"25","author":"Vega Alanis","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.bbrc.2024.150218_bib21","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.neuron.2017.02.023","article-title":"GARLH family proteins stabilize GABAA receptors at synapses","volume":"93","author":"Yamasaki","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib22","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.celrep.2017.09.025","article-title":"An essential role for the tetraspanin LHFPL4 in the cell-type-specific targeting and clustering of synaptic GABAA receptors","volume":"21","author":"Davenport","year":"2017","journal-title":"Cell Rep"},{"key":"10.1016\/j.bbrc.2024.150218_bib23","doi-asserted-by":"crossref","first-page":"12394","DOI":"10.1074\/jbc.M116.724443","article-title":"Proteomic characterization of inhibitory synapses using a novel phluorin-tagged \u03b3-aminobutyric acid receptor, type A (GABAA), \u03b12 subunit knock-in mouse","volume":"291","author":"Nakamura","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2024.150218_bib24","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1126\/science.aag0821","article-title":"Identification of an elaborate complex mediating postsynaptic inhibition","volume":"353","author":"Uezu","year":"2016","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib25","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.tins.2020.10.011","article-title":"Regulation of GABAARs by transmembrane accessory proteins","volume":"44","author":"Han","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib26","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1016\/j.celrep.2018.04.015","article-title":"Impairment of inhibitory synapse formation and motor behavior in mice lacking the NL2 binding partner LHFPL4\/GARLH4","volume":"23","author":"Wu","year":"2018","journal-title":"Cell Rep"},{"key":"10.1016\/j.bbrc.2024.150218_bib27","article-title":"Assembly rules for GABAA receptor complexes in the brain","volume":"6","author":"Martenson","year":"2017","journal-title":"Eife"},{"key":"10.1016\/j.bbrc.2024.150218_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0039572","article-title":"The biochemical anatomy of cortical inhibitory synapses","volume":"7","author":"Heller","year":"2012","journal-title":"Plos One"},{"key":"10.1016\/j.bbrc.2024.150218_bib29","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.neuron.2009.08.023","article-title":"Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin","volume":"63","author":"Poulopoulos","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib30","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.brainresbull.2016.07.004","article-title":"Regulation of GABAergic synapse development by postsynaptic membrane proteins","volume":"129","author":"Lu","year":"2017","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bbrc.2024.150218_bib31","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.neuron.2017.10.003","article-title":"Molecular dissection of neuroligin 2 and Slitrk3 reveals an essential framework for GABAergic synapse development","volume":"96","author":"Li","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib32","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.neuron.2017.12.038","article-title":"Clptm1 limits forward trafficking of GABAA receptors to scale inhibitory synaptic strength","volume":"97","author":"Ge","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib33","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrg2933","article-title":"Cleft lip and palate: understanding genetic and environmental influences","volume":"12","author":"Dixon","year":"2011","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.bbrc.2024.150218_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0009758","article-title":"Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice","volume":"5","author":"Oh","year":"2010","journal-title":"Plos One"},{"key":"10.1016\/j.bbrc.2024.150218_bib35","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.ntt.2004.04.002","article-title":"Cleft palate by picrotoxin or 3-MP and palatal shelf elevation in GABA-deficient mice","volume":"26","author":"Ding","year":"2004","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.bbrc.2024.150218_bib36","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1126\/science.aax5719","article-title":"Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions","volume":"366","author":"Han","year":"2019","journal-title":"Science"},{"issue":"47","key":"10.1016\/j.bbrc.2024.150218_bib37","doi-asserted-by":"crossref","first-page":"8758","DOI":"10.1523\/JNEUROSCI.0510-22.2022","article-title":"Shisa7-Dependent regulation of GABAA receptor single-channel gating kinetics","volume":"42","author":"Castellano","year":"2022","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib38","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.24192","article-title":"The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory","volume":"6","author":"Schmitz","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.bbrc.2024.150218_bib39","doi-asserted-by":"crossref","first-page":"7077","DOI":"10.1523\/JNEUROSCI.14-11-07077.1994","article-title":"Assembly of GABAA receptor subunits: role of the delta subunit","volume":"14","author":"Saxena","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib40","article-title":"Structure and pharmacology of gamma-amino-butyric acid A receptor subtypes","volume":"47","author":"Sieghart","year":"1995","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.bbrc.2024.150218_bib41","series-title":"Transporters and Metabolism","first-page":"157","article-title":"GABAA-receptor subtypes: pharmacological significance and mutational analysis in vivo in GABA: receptors","author":"Mohler","year":"1996"},{"key":"10.1016\/j.bbrc.2024.150218_bib42","doi-asserted-by":"crossref","first-page":"7243","DOI":"10.1021\/jm800889m","article-title":"Structural requirements for eszopiclone and zolpidem binding to the \u03b3-aminobutyric acid type-A (GABAA) receptor are different","volume":"51","author":"Hanson","year":"2008","journal-title":"J. Med. Chem."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib43","doi-asserted-by":"crossref","first-page":"859","DOI":"10.4155\/fmc.10.178","article-title":"Insights into the structure and pharmacology of GABAA receptors","volume":"2","author":"Carter","year":"2010","journal-title":"Future Med. Chem."},{"issue":"8","key":"10.1016\/j.bbrc.2024.150218_bib44","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1212\/WNL.0b013e318247cd03","article-title":"GABAB receptors: structure, functions, and clinical implications","volume":"78","author":"Benarroch","year":"2012","journal-title":"Neurology"},{"issue":"17\u201318","key":"10.1016\/j.bbrc.2024.150218_bib45","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.drudis.2009.06.009","article-title":"The complexity of the GABAA receptor shapes unique pharmacological profiles","volume":"14","author":"D'Hulst","year":"2009","journal-title":"Drug Discov. Today"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib46","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1527-3458.2005.tb00049.x","article-title":"Clinical potential of GABAB receptor modulators","volume":"11","author":"Ong","year":"2005","journal-title":"CNS Drug Rev."},{"issue":"10","key":"10.1016\/j.bbrc.2024.150218_bib47","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/S0042-6989(97)00277-0","article-title":"Molecular composition of GABAC receptors","volume":"38","author":"Enz","year":"1998","journal-title":"Vis. Res."},{"issue":"13","key":"10.1016\/j.bbrc.2024.150218_bib48","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1111\/bph.13768","article-title":"GABA-\u03c1 receptors: distinctive functions and molecular pharmacology","volume":"174","author":"Naffaa","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib49","doi-asserted-by":"crossref","first-page":"17522","DOI":"10.1073\/pnas.1419632111","article-title":"GABA\u03c1 subunits confer a bicuculline\u2010insensitive component to GFAP+ cells of cerebellum","volume":"111","author":"P\u00e9triz","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"8","key":"10.1016\/j.bbrc.2024.150218_bib50","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1515\/BC.2001.141","article-title":"GABA(C) receptors: a molecular view","volume":"382","author":"Enz","year":"2001","journal-title":"Biol. Chem."},{"key":"10.1016\/j.bbrc.2024.150218_bib51","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1523\/JNEUROSCI.14-03-01202.1994","article-title":"A novel GABA receptor on bipolar cell terminals in the tiger salamander retina","volume":"14","author":"Lukasiewicz","year":"1994","journal-title":"J. Neurosci."},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib52","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.pnpbp.2007.11.023","article-title":"High-field MRS study of GABA, glutamate and glutamine in social anxiety disorder: response to treatment with levetiracetam","volume":"32","author":"Pollack","year":"2008","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib53","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/biof.5520260305","article-title":"Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans","volume":"26","author":"Abdou","year":"2006","journal-title":"Biofactors"},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib54","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1055\/s-0029-1241798","article-title":"Effects of the GABA-reuptake inhibitor tiagabine on panic and anxiety in patients with panic disorder","volume":"42","author":"Zwanzger","year":"2009","journal-title":"Pharmacopsychiatry"},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib55","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1089\/acm.2007.6338","article-title":"Yoga Asana sessions increase brain GABA levels: a pilot study","volume":"13","author":"Streeter","year":"2007","journal-title":"J. Alternative Compl. Med."},{"issue":"11","key":"10.1016\/j.bbrc.2024.150218_bib56","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1089\/acm.2010.0007","article-title":"Effects of yoga versus walking on mood, anxiety, and brain GABA levels: a randomized controlled MRS study","volume":"16","author":"Streeter","year":"2010","journal-title":"J. Alternative Compl. Med."},{"key":"10.1016\/j.bbrc.2024.150218_bib57","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fpsyt.2018.00044","article-title":"Vagus nerve as modulator of the brain-gut Axis in psychiatric and inflammatory disorders","volume":"9","author":"Breit","year":"2018","journal-title":"Front. Psychiatr."},{"key":"10.1016\/j.bbrc.2024.150218_bib58","doi-asserted-by":"crossref","first-page":"103669","DOI":"10.1016\/j.jff.2019.103669","article-title":"Gamma-aminobutyric acid and probiotics: multiple health benefits and their future in the global functional food and nutraceuticals market","volume":"64","author":"Diez-Gutierrez","year":"2020","journal-title":"J. Funct. Foods"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib59","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/s41564-018-0307-3","article-title":"GABA-modulating bacteria of the human gut microbiota","volume":"4","author":"Strandwitz","year":"2019","journal-title":"Nat Microbiol"},{"issue":"38","key":"10.1016\/j.bbrc.2024.150218_bib60","doi-asserted-by":"crossref","first-page":"16050","DOI":"10.1073\/pnas.1102999108","article-title":"Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve","volume":"108","author":"Bravo","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib61","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.neuron.2019.02.008","article-title":"Gut microbe to brain signaling: what happens in vagus","volume":"101","author":"Fulling","year":"2019","journal-title":"Neuron"},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib62","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1249\/MSS.0000000000001495","article-title":"Exercise alters gut microbiota composition and function in lean and obese humans","volume":"50","author":"Allen","year":"2018","journal-title":"Med. Sci. Sports Exerc."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib63","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1249\/JES.0000000000000183","article-title":"Exercise and the gut microbiome: a review of the evidence, potential mechanisms, and implications for human health","volume":"47","author":"Mailing","year":"2019","journal-title":"Exerc. Sport Sci. Rev."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib64","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s00213-016-4506-4","article-title":"GABAA receptor occupancy by subtype selective GABAA\u03b12,3 modulators: PET studies in humans","volume":"234","author":"Jucaite","year":"2017","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.bbrc.2024.150218_bib65","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.schres.2017.09.014","article-title":"Pregabalin for anxiety in patients with schizophrenia - a randomized, double-blind placebo-controlled study","volume":"195","author":"Schjerning","year":"2018","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib66","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1176\/appi.ajp.160.3.533","article-title":"Pregabalin in generalized anxiety disorder: a placebo-controlled trial","volume":"160","author":"Pande","year":"2003","journal-title":"Am. J. Psychiatr."},{"issue":"10","key":"10.1016\/j.bbrc.2024.150218_bib67","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1038\/nn.4086","article-title":"Mechanisms of stress in the brain","volume":"18","author":"McEwen","year":"2015","journal-title":"Nat. Neurosci."},{"issue":"10","key":"10.1016\/j.bbrc.2024.150218_bib68","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1038\/mp.2016.118","article-title":"Cellular and molecular basis for stress-induced depression","volume":"22","author":"Seo","year":"2017","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.bbrc.2024.150218_bib69","doi-asserted-by":"crossref","first-page":"103","DOI":"10.31887\/DCNS.2005.7.2\/mmeaney","article-title":"Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome","volume":"7","author":"Meaney","year":"2005","journal-title":"Dialogues Clin. Neurosci."},{"issue":"22","key":"10.1016\/j.bbrc.2024.150218_bib70","doi-asserted-by":"crossref","first-page":"6828","DOI":"10.1073\/pnas.1411260111","article-title":"Stress and the dynamic genome: steroids, epigenetics, and the transposome","volume":"112","author":"Hunter","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2024.150218_bib71","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1038\/220911a0","article-title":"Selective retention of corticosterone by limbic structures in rat brain","volume":"220","author":"McEwen","year":"1968","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2024.150218_bib72","series-title":"Receptor Dynamics in Neural Development","first-page":"141","author":"Cameron","year":"1996"},{"key":"10.1016\/j.bbrc.2024.150218_bib73","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1146\/annurev.neuro.22.1.105","article-title":"Stress and hippocampal plasticity","volume":"22","author":"McEwen","year":"1999","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib74","doi-asserted-by":"crossref","first-page":"6810","DOI":"10.1523\/JNEUROSCI.22-15-06810.2002","article-title":"Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons","volume":"22","author":"Vyas","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib75","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.neuroscience.2006.08.075","article-title":"Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator","volume":"144","author":"Bennur","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbrc.2024.150218_bib76","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.biopsych.2012.04.008","article-title":"Glucocorticoids protect against the delayed behavioral and cellular effects of acute stress on the amygdala","volume":"72","author":"Rao","year":"2012","journal-title":"Biol. Psychiatr."},{"key":"10.1016\/j.bbrc.2024.150218_bib77","doi-asserted-by":"crossref","first-page":"7870","DOI":"10.1523\/JNEUROSCI.1184-06.2006","article-title":"Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting","volume":"26","author":"Liston","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib78","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1152\/physrev.00041.2006","article-title":"Physiology and neurobiology of stress and adaptation: central role of the brain","volume":"87","author":"McEwen","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbrc.2024.150218_bib79","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.neuron.2013.06.028","article-title":"The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course","volume":"79","author":"McEwen","year":"2013","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib80","doi-asserted-by":"crossref","first-page":"293","DOI":"10.4103\/aca.aca_80_21","article-title":"Preoperative anxiety among cardiac surgery patients and its impact on major adverse cardiac events and mortality- A randomized, parallel-group study","volume":"25","author":"Mudgalkar","year":"2022","journal-title":"Ann. Card Anaesth."},{"key":"10.1016\/j.bbrc.2024.150218_bib81","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.euroneuro.2017.12.007","article-title":"Cortical control of aggression: GABA signalling in the anterior cingulate cortex","volume":"30","author":"Jager","year":"2020","journal-title":"Eur. Neuropsychopharmacol"},{"key":"10.1016\/j.bbrc.2024.150218_bib82","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2021.147440","article-title":"GABA-A receptor signaling in the anterior cingulate cortex modulates aggression and anxiety-related behaviors in socially isolated mice","volume":"1762","author":"Chaibi","year":"2021","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib83","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/j.1526-4637.2010.00826.x","article-title":"Gabapentin does not reduce preoperative anxiety when given prior to total hip arthroplasty","volume":"11","author":"Clarke","year":"2010","journal-title":"Pain Med."},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109411","article-title":"Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation","volume":"36","author":"Li","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150218_bib85","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.691931","article-title":"Electroacupuncture ameliorates chronic inflammatory pain-related anxiety by activating PV interneurons in the anterior cingulate cortex","volume":"15","author":"Shao","year":"2021","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib86","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0001407","article-title":"Neurabin contributes to hippocampal long-term potentiation and contextual fear memory","volume":"3","author":"Wu","year":"2008","journal-title":"Plos One"},{"key":"10.1016\/j.bbrc.2024.150218_bib87","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1756-6606-4-6","article-title":"Neurabin in the anterior cingulate cortex regulates anxiety-like behavior in adult mice","volume":"4","author":"Kim","year":"2011","journal-title":"Mol. Brain"},{"issue":"7","key":"10.1016\/j.bbrc.2024.150218_bib88","doi-asserted-by":"crossref","first-page":"3936","DOI":"10.1002\/ptr.7106","article-title":"Scutellarin ameliorates the stress-induced anxiety-like behaviors in mice by regulating neurotransmitters","volume":"35","author":"Guo","year":"2021","journal-title":"Phytother Res."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib89","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/cercor\/bht279","article-title":"Disrupted effective connectivity between the amygdala and orbitofrontal cortex in social anxiety disorder during emotion discrimination revealed by dynamic causal modeling for fMRI","volume":"25","author":"Sladky","year":"2015","journal-title":"Cerebr. Cortex"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib90","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.biopsych.2014.02.014","article-title":"Ventromedial prefrontal cortex is critical for the regulation of amygdala activity in humans","volume":"77","author":"Motzkin","year":"2015","journal-title":"Biol. Psychiatr."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib91","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/mp.2011.88","article-title":"Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders","volume":"17","author":"Myers-Schulz","year":"2012","journal-title":"Mol. Psychiatr."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib92","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1093\/scan\/nsv155","article-title":"GABA content within the ventromedial prefrontal cortex is related to trait anxiety","volume":"11","author":"Delli Pizzi","year":"2016","journal-title":"Soc. Cognit. Affect Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib93","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.neubiorev.2014.07.016","article-title":"Associations of regional GABA and glutamate with intrinsic and extrinsic neural activity in humans\u2014a review of multimodal imaging studies","volume":"47","author":"Duncan","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.bbrc.2024.150218_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2023.110755","article-title":"GABAB1 receptor knockdown in prefrontal cortex induces behavioral aberrations associated with autism spectrum disorder in mice","volume":"202","author":"Wang","year":"2023","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bbrc.2024.150218_bib95","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2020.108411","article-title":"Molecular and neuronal mechanisms underlying the effects of adolescent nicotine exposure on anxiety and mood disorders","volume":"184","author":"Laviolette","year":"2021","journal-title":"Neuropharmacology"},{"issue":"11","key":"10.1016\/j.bbrc.2024.150218_bib96","doi-asserted-by":"crossref","first-page":"3322","DOI":"10.1523\/JNEUROSCI.4250-15.2016","article-title":"Anxiety evokes hypofrontality and disrupts rule-relevant encoding by dorsomedial prefrontal cortex neurons","volume":"36","author":"Park","year":"2016","journal-title":"J. Neurosci."},{"issue":"36","key":"10.1016\/j.bbrc.2024.150218_bib97","doi-asserted-by":"crossref","first-page":"86352","DOI":"10.1007\/s11356-023-28426-8","article-title":"Arsenic exposure induced anxiety-like behaviors in male mice via influencing the GABAergic Signaling in the prefrontal cortex","volume":"30","author":"Hu","year":"2023","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.bbrc.2024.150218_bib98","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.neuroscience.2018.08.030","article-title":"Adolescent stress disrupts the maturation of anxiety-related behaviors and alters the developmental trajectory of the prefrontal cortex in a sex- and age-specific manner","volume":"390","author":"Page","year":"2018","journal-title":"Neuroscience"},{"issue":"8","key":"10.1016\/j.bbrc.2024.150218_bib99","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.3390\/brainsci12081015","article-title":"Altered development of prefrontal gabaergic functions and anxiety-like behavior in adolescent offspring induced by prenatal stress","volume":"12","author":"Suwaluk","year":"2022","journal-title":"Brain Sci."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib100","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1038\/npp.2013.302","article-title":"The role of the medial prefrontal cortex in regulating social familiarity-induced anxiolysis","volume":"39","author":"Lungwitz","year":"2014","journal-title":"Neuropsychopharmacology"},{"issue":"21","key":"10.1016\/j.bbrc.2024.150218_bib101","doi-asserted-by":"crossref","first-page":"5000","DOI":"10.1523\/JNEUROSCI.0143-04.2004","article-title":"Corticotropin-releasing factor and acute stress prolongs serotonergic regulation of GABA transmission in prefrontal cortical pyramidal neurons","volume":"24","author":"Tan","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib102","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neubiorev.2019.07.024","article-title":"Prefrontal excitatory\/inhibitory balance in stress and emotional disorders: evidence for over-inhibition","volume":"105","author":"Page","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.bbrc.2024.150218_bib103","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.ebiom.2018.07.031","article-title":"Quercetin reduces cortical GABAergic transmission and alleviates MK-801-induced hyperactivity","volume":"34","author":"Fan","year":"2018","journal-title":"EBioMedicine"},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib104","doi-asserted-by":"crossref","first-page":"795","DOI":"10.33549\/physiolres.933776","article-title":"Quercetin protects against stress-induced anxiety- and depression-like behavior and improves memory in male mice","volume":"67","author":"Samad","year":"2018","journal-title":"Physiol. Res."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib105","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.neuron.2014.04.042","article-title":"Amygdala microcircuits controlling learned fear","volume":"82","author":"Duvarci","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib106","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.nlm.2016.07.025","article-title":"Bridging the gap: towards a cell-type specific understanding of neural circuits underlying fear behaviors","volume":"135","author":"McCullough","year":"2016","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.bbrc.2024.150218_bib107","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchemneu.2022.102185","article-title":"The regional and cellular distribution of GABAA receptor subunits in the human amygdala","volume":"126","author":"Song","year":"2022","journal-title":"J. Chem. Neuroanat."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib108","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.neuropharm.2012.03.001","article-title":"Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice","volume":"63","author":"Smith","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbrc.2024.150218_bib109","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3389\/neuro.08.037.2009","article-title":"The alpha 1 subunit of the GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala","volume":"3","author":"Wiltgen","year":"2009","journal-title":"Front. Behav. Neurosci."},{"issue":"12","key":"10.1016\/j.bbrc.2024.150218_bib110","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1111\/j.1460-9568.2007.05970.x","article-title":"Training-induced changes in the expression of GABAA-associated genes in the amygdala after the acquisition and extinction of Pavlovian fear","volume":"26","author":"Heldt","year":"2007","journal-title":"Eur. J. Neurosci."},{"issue":"21","key":"10.1016\/j.bbrc.2024.150218_bib111","doi-asserted-by":"crossref","first-page":"7139","DOI":"10.1523\/JNEUROSCI.0693-10.2010","article-title":"Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice","volume":"30","author":"Heldt","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib112","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3389\/fncel.2016.00039","article-title":"Enrichment of GABAA receptor alpha-subunits on the axonal initial segment shows regional differences","volume":"10","author":"Gao","year":"2016","journal-title":"Front. Cell. Neurosci."},{"issue":"12","key":"10.1016\/j.bbrc.2024.150218_bib113","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.biopsych.2016.06.022","article-title":"Delta subunit-containing gamma-aminobutyric acid A receptor disinhibits lateral amygdala and facilitates fear expression in mice","volume":"81","author":"Liu","year":"2017","journal-title":"Biol. Psychiatr."},{"key":"10.1016\/j.bbrc.2024.150218_bib114","first-page":"27","article-title":"Delta-subunit-containing GABAA-receptors mediate tonic inhibition in paracapsular cells of the mouse amygdala","volume":"8","author":"Marowsky","year":"2014","journal-title":"Front. Neural Circ."},{"key":"10.1016\/j.bbrc.2024.150218_bib115","first-page":"32","article-title":"Functional expression of the GABA(A) receptor alpha2 and alpha3 subunits at synapses between intercalated medial paracapsular neurons of mouse amygdala","volume":"6","author":"Geracitano","year":"2012","journal-title":"Front. Neural Circ."},{"issue":"7501","key":"10.1016\/j.bbrc.2024.150218_bib116","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nature13258","article-title":"Amygdala interneuron subtypes control fear learning through disinhibition","volume":"509","author":"Wolff","year":"2014","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib117","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1111\/j.1460-9568.2004.03574.x","article-title":"Functional mapping of GABAA receptor subtypes in the amygdala","volume":"20","author":"Marowsky","year":"2004","journal-title":"Eur. J. Neurosci."},{"issue":"25","key":"10.1016\/j.bbrc.2024.150218_bib118","doi-asserted-by":"crossref","first-page":"8611","DOI":"10.1523\/JNEUROSCI.4404-11.2012","article-title":"Tonic inhibition in principal cells of the amygdala: a central role for alpha3 subunit-containing GABAA receptors","volume":"32","author":"Marowsky","year":"2012","journal-title":"J. Neurosci."},{"issue":"7321","key":"10.1016\/j.bbrc.2024.150218_bib119","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/nature09559","article-title":"Encoding of conditioned fear in central amygdala inhibitory circuits","volume":"468","author":"Ciocchi","year":"2010","journal-title":"Nature"},{"issue":"7321","key":"10.1016\/j.bbrc.2024.150218_bib120","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/nature09553","article-title":"Genetic dissection of an amygdala microcircuit that gates conditioned fear","volume":"468","author":"Haubensak","year":"2010","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.bbrc.2024.150218_bib121","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1038\/nn.4102","article-title":"Regulating anxiety with extrasynaptic inhibition","volume":"18","author":"Botta","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib122","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.neuroscience.2013.01.008","article-title":"Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain","volume":"236","author":"H\u00f6rtnagl","year":"2013","journal-title":"Neuroscience"},{"issue":"8","key":"10.1016\/j.bbrc.2024.150218_bib123","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1523\/JNEUROSCI.2490-12.2013","article-title":"Novel subunit-specific tonic GABA currents and differential effects of ethanol in the central amygdala of CRF receptor-1 reporter mice","volume":"33","author":"Herman","year":"2013","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib124","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.biopsych.2011.05.036","article-title":"Site-specific genetic manipulation of amygdala corticotropin-releasing factor reveals its imperative role in mediating behavioral response to challenge","volume":"71","author":"Regev","year":"2012","journal-title":"Biol. Psychiatr."},{"issue":"40","key":"10.1016\/j.bbrc.2024.150218_bib125","doi-asserted-by":"crossref","first-page":"16330","DOI":"10.1073\/pnas.1119261109","article-title":"Cell-type specific deletion of GABA(A)alpha1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction","volume":"109","author":"Gafford","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2024.150218_bib126","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1146\/annurev-pharmtox-011613-135947","article-title":"GABAA receptor subtypes: therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism","volume":"54","author":"Rudolph","year":"2014","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bbrc.2024.150218_bib127","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0896-6273(00)80375-X","article-title":"Fear conditioning enhances different temporal components of tone-evoked spike trains in auditory cortex and lateral amygdala","volume":"19","author":"Quirk","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib128","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1101\/lm.7.2.97","article-title":"Differential fear conditioning induces reciprocal changes in the sensory responses of lateral amygdala neurons to the CS+ and CS","volume":"7","author":"Collins","year":"2000","journal-title":"Learn. Mem."},{"key":"10.1016\/j.bbrc.2024.150218_bib129","doi-asserted-by":"crossref","first-page":"4047","DOI":"10.1046\/j.1460-9568.2000.00281.x","article-title":"Auditory fear conditioning increases CS-elicited spike firing in lateral amygdala neurons even after extensive overtraining","volume":"12","author":"Maren","year":"2000","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib130","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/37601","article-title":"Fear conditioning induces associative long-term potentiation in the amygdala","volume":"390","author":"Rogan","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2024.150218_bib131","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/37605","article-title":"Fear conditioning induces a lasting potentiation of synaptic currents in vitro","volume":"390","author":"McKernan","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2024.150218_bib132","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1126\/science.1195298","article-title":"Calcium-permeable AMPA receptor dynamics mediate fear memory erasure","volume":"330","author":"Clem","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2024.150218_bib133","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1126\/science.1103944","article-title":"Postsynaptic receptor trafficking underlying a form of associative learning","volume":"308","author":"Rumpel","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2024.150218_bib134","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/nn.3322","article-title":"Experience-dependent modification of a central amygdala fear circuit","volume":"16","author":"Li","year":"2013","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib135","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/nature09820","article-title":"Amygdala circuitry mediating reversible and bidirectional control of anxiety","volume":"471","author":"Tye","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2024.150218_bib136","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/nn.3767","article-title":"Central amygdala PKC-\u03b4+ neurons mediate the influence of multiple anorexigenic signals","volume":"17","author":"Cai","year":"2014","journal-title":"Nat. Neurosci."},{"issue":"7534","key":"10.1016\/j.bbrc.2024.150218_bib137","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/nature14188","article-title":"From circuits to behaviour in the amygdala","volume":"517","author":"Janak","year":"2015","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib138","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.neuron.2013.06.016","article-title":"BLA to vHPC inputs modulate anxiety-related behaviors","volume":"79","author":"Felix-Ortiz","year":"2013","journal-title":"Neuron"},{"issue":"7444","key":"10.1016\/j.bbrc.2024.150218_bib139","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/nature12018","article-title":"Diverging neural pathways assemble a behavioural state from separable features in anxiety","volume":"496","author":"Kim","year":"2013","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib140","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.biopsych.2018.06.019","article-title":"Chronic stress remodels synapses in an amygdala circuit-specific manner","volume":"85","author":"Zhang","year":"2019","journal-title":"Biol. Psychiatr."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib141","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/npp.2008.71","article-title":"Stress impairs 5-HT2A receptor-mediated serotonergic facilitation of GABA release in juvenile rat basolateral amygdala","volume":"34","author":"Jiang","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbrc.2024.150218_bib142","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1756-6606-7-32","article-title":"Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currents","volume":"7","author":"Liu","year":"2014","journal-title":"Mol. Brain"},{"key":"10.1016\/j.bbrc.2024.150218_bib143","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1038\/npp.2016.33","article-title":"Effects of repeated stress on age-dependent GABAergic regulation of the lateral nucleus of the amygdala","volume":"41","author":"Zhang","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"32","key":"10.1016\/j.bbrc.2024.150218_bib144","doi-asserted-by":"crossref","first-page":"8461","DOI":"10.1523\/JNEUROSCI.2279-15.2016","article-title":"Acute stress suppresses synaptic inhibition and increases anxiety via endocannabinoid release in the basolateral amygdala","volume":"36","author":"Di","year":"2016","journal-title":"J. Neurosci."},{"issue":"7","key":"10.1016\/j.bbrc.2024.150218_bib145","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.neuroscience.2011.03.051","article-title":"Altered GABA transmission in a mouse model of increased trait anxiety","volume":"183","author":"Tasan","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbrc.2024.150218_bib146","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.neuroscience.2013.10.064","article-title":"Unpredictable neonatal stress enhances adult anxiety and alters amygdala gene expression related to serotonin and GABA","volume":"258","author":"Sarro","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbrc.2024.150218_bib147","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.brainres.2008.03.006","article-title":"GABA homeostasis contributes to the developmental programming of anxiety-related behavior","volume":"1210","author":"Depino","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.bbrc.2024.150218_bib148","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.175854","article-title":"Coronaridine congeners induce sedative and anxiolytic-like activity in na\u00efve and stressed\/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA","volume":"953","author":"Arias","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib149","doi-asserted-by":"crossref","DOI":"10.1016\/j.pneurobio.2020.101952","article-title":"IL-10 normalizes aberrant amygdala GABA transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intake","volume":"199","author":"Patel","year":"2021","journal-title":"Prog. Neurobiol."},{"issue":"49","key":"10.1016\/j.bbrc.2024.150218_bib150","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2213120119","article-title":"Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala","volume":"119","author":"Jones","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"12","key":"10.1016\/j.bbrc.2024.150218_bib151","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.biopsych.2010.04.027","article-title":"Amygdala activity, fear, and anxiety: modulation by stress","volume":"67","author":"Ressler","year":"2010","journal-title":"Biol. Psychiatr."},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib152","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nrn3945","article-title":"Neuronal circuits for fear and anxiety","volume":"16","author":"Tovote","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib153","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.neuron.2009.11.031","article-title":"Are the dorsal and ventral hippocampus functionally distinct structures?","volume":"65","author":"Fanselow","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib154","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/FBP.0b013e3282de7929","article-title":"The role of hippocampus in anxiety: intracerebral infusion studies","volume":"18","author":"Engin","year":"2007","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib155","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.14120","article-title":"Modulation of anxiety and fear via distinct intrahippocampal circuits","volume":"5","author":"Engin","year":"2016","journal-title":"Elife"},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib156","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00213-013-3276-5","article-title":"Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability","volume":"230","author":"Matthew","year":"2013","journal-title":"Psychopharmacology (Berl)"},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib157","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/nn1469","article-title":"Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety","volume":"8","author":"Maguire","year":"2005","journal-title":"Nat. Neurosci."},{"issue":"10","key":"10.1016\/j.bbrc.2024.150218_bib158","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1002\/hipo.22604","article-title":"Reduced tonic inhibition in the dentate gyrus contributes to chronic stress-induced impairments in learning and memory","volume":"26","author":"Lee","year":"2016","journal-title":"Hippocampus"},{"issue":"40","key":"10.1016\/j.bbrc.2024.150218_bib159","doi-asserted-by":"crossref","first-page":"13698","DOI":"10.1523\/JNEUROSCI.1370-15.2015","article-title":"Tonic inhibitory control of dentate gyrus granule cells by alpha5-containing GABAA receptors reduces memory interference","volume":"35","author":"Engin","year":"2015","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib160","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.tins.2021.10.010","article-title":"Neurobiology of the lateral septum: regulation of social behavior","volume":"45","author":"Menon","year":"2022","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib161","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.brainresrev.2004.04.009","article-title":"Regulation of affect by the lateral septum: implications for neuropsychiatry","volume":"46","author":"Sheehan","year":"2004","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.bbrc.2024.150218_bib162","series-title":"The Behavioral Neuroscience of the Septal Region","first-page":"1","article-title":"On the basic architecture of the septal region","author":"Swanson","year":"2000"},{"key":"10.1016\/j.bbrc.2024.150218_bib163","first-page":"5","article-title":"Septo-hippocampo-septal loop and memory formation","volume":"4","author":"Khakpai","year":"2013","journal-title":"Basic Clin. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib164","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.celrep.2014.02.030","article-title":"Cell-type-specific circuit connectivity of hippocampal CA1 revealed through Cre-dependent rabies tracing","volume":"7","author":"Sun","year":"2014","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150218_bib165","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1126\/science.1247485","article-title":"Dendritic inhibition in the hippocampus supports fear learning","volume":"343","author":"Lovett-Barron","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2024.150218_bib166","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/hipo.1109","article-title":"Cholinergic system regulation of spatial representation by the hippocampus","volume":"12","author":"Ikonen","year":"2002","journal-title":"Hippocampus"},{"key":"10.1016\/j.bbrc.2024.150218_bib167","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/syn.20184","article-title":"Characterization of medial septal glutamatergic neurons and their projection to the hippocampus","volume":"58","author":"Colom","year":"2005","journal-title":"Synapse"},{"key":"10.1016\/j.bbrc.2024.150218_bib168","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.neuron.2015.05.001","article-title":"Locomotion, theta oscillations, and the speed-correlated firing of hippocampal neurons are controlled by a medial septal glutamatergic circuit","volume":"86","author":"Fuhrmann","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150218_bib169","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.brainresbull.2005.06.018","article-title":"Input from the medial septum regulates adult hippocampal neurogenesis","volume":"67","author":"Van der Borght","year":"2005","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bbrc.2024.150218_bib170","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1093\/cercor\/bht060","article-title":"The GABAergic septohippocampal pathway is directly involved in internal processes related to operant reward learning","volume":"24","author":"Vega-Flores","year":"2014","journal-title":"Cerebr. Cortex"},{"key":"10.1016\/j.bbrc.2024.150218_bib171","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0091-3057(01)00541-X","article-title":"Septal GABAergic and hippocampal cholinergic systems modulate anxiety in the plus-maze and shock-probe tests","volume":"69","author":"Degroot","year":"2001","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.bbrc.2024.150218_bib172","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.conb.2013.01.021","article-title":"The long and short ofGABAergic neurons","volume":"23","author":"Caputi","year":"2013","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.bbrc.2024.150218_bib173","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0301-0082(95)98600-A","article-title":"Activities of neurons within the rat dorsolateral septal nucleus (DLSN)","volume":"45","author":"Gallagher","year":"1995","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.bbrc.2024.150218_bib174","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0165-0173(97)00009-X","article-title":"Connections of the rat lateral septal complex","volume":"24","author":"Risold","year":"1997","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.bbrc.2024.150218_bib175","series-title":"The Behavioral Neuroscience of the Septal Region","first-page":"175","article-title":"The septal region and social behavior","author":"Sheehan","year":"2000"},{"key":"10.1016\/j.bbrc.2024.150218_bib176","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.cub.2015.12.065","article-title":"Effective modulation of male aggression through lateral septum to medial hypothalamus projection","volume":"26","author":"Wong","year":"2016","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bbrc.2024.150218_bib177","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1038\/s41467-021-23064-5","article-title":"Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats","volume":"12","author":"Oliveira","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2024.150218_bib178","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1097\/00005053-195812000-00002","article-title":"Tumors of the septum pellucidum and adjacent structures with abnormal affective behavior: an anterior midline structure syndrome","volume":"127","author":"Zeman","year":"1958","journal-title":"J. Nerv. Ment. Dis."},{"key":"10.1016\/j.bbrc.2024.150218_bib179","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0163-1047(80)91247-9","article-title":"The septal forebrain and the inhibitory modulation of attack and defense in the rat. A review","volume":"30","author":"Albert","year":"1980","journal-title":"Behav. Neural. Biol."},{"key":"10.1016\/j.bbrc.2024.150218_bib180","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0031-9384(81)90167-0","article-title":"Effects of anteroventral septal lesions on intraspecific aggression in male hamsters","volume":"26","author":"Potegal","year":"1981","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbrc.2024.150218_bib181","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.brainres.2011.12.042","article-title":"GABAA receptor activation in the lateral septum reduces the expression of conditioned defeat and increases aggression in Syrian hamsters","volume":"1439","author":"McDonald","year":"2012","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib182","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/npp.2010.213","article-title":"The modulatory role of the lateral septum on neuroendocrine and behavioral stress responses","volume":"36","author":"Singewald","year":"2011","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib183","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/sj.npp.1301414","article-title":"Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine","volume":"33","author":"Navailles","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbrc.2024.150218_bib184","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.neuropharm.2015.01.021","article-title":"Dorsal raphe 5-HT(2C) receptor and GABA networks regulate anxiety produced by cocaine withdrawal","volume":"93","author":"Craige","year":"2015","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbrc.2024.150218_bib185","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2023.109645","article-title":"The \u03b11 and \u03b32 subunit-containing GABAA receptor-mediated inhibitory transmission in the anteroventral bed nucleus of stria terminalis is involved in the regulation of anxiety in rats with substantia nigra lesions","volume":"237","author":"Li","year":"2023","journal-title":"Neuropharmacology"},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib186","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110775","article-title":"An extended amygdala-midbrain circuit controlling cocaine withdrawal-induced anxiety and reinstatement","volume":"39","author":"Tian","year":"2022","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib187","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000131110","article-title":"GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors","volume":"82","author":"Hajizadeh Moghaddam","year":"2008","journal-title":"Pharmacology"},{"key":"10.1016\/j.bbrc.2024.150218_bib188","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/1744-9081-8-61","article-title":"GABAergic neuroactive steroids: a new frontier in bipolar disorders?","volume":"8","author":"Carta","year":"2012","journal-title":"Behav. Brain Funct."},{"issue":"3\u20134","key":"10.1016\/j.bbrc.2024.150218_bib189","first-page":"197","article-title":"Pharmacology of endogenous neuroactive steroids","volume":"15","author":"Reddy","year":"2003","journal-title":"Crit. Rev. Neurobiol."},{"issue":"2\u20133","key":"10.1016\/j.bbrc.2024.150218_bib190","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ejphar.2007.06.028","article-title":"Antagonism of neurosteroid modulation of native gamma-aminobutyric acid receptors by (3alpha,5alpha)-17-phenylandrost-16-en-3-ol","volume":"572","author":"Kelley","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib191","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.pneurobio.2003.09.001","article-title":"Neuroactive steroid modulation of GABAA receptors","volume":"71","author":"Lambert","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.bbrc.2024.150218_bib192","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S1054-3589(06)54008-6","article-title":"From gene to behavior and back again: new perspectives on GABAA receptor subunit selectivity of alcohol actions","volume":"54","author":"Boehm","year":"2006","journal-title":"Adv. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib193","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0006-8993(99)01381-5","article-title":"Sulfated and unsulfated steroids modulate \u03b3 aminobutyric acidA receptor function through distinct sites","volume":"830","author":"Park-Chung","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.bbrc.2024.150218_bib194","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1469-7793.2001.0673e.x","article-title":"Pregnenolone sulfate block of GABAA receptors: mechanism and involvement of a residue in the M2 region of the \u03b1 subunit","volume":"532","author":"Akk","year":"2001","journal-title":"J. Physiol."},{"key":"10.1016\/j.bbrc.2024.150218_bib195","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1124\/mol.64.4.857","article-title":"A presynaptic action of the neurosteroid pregnenolone sulfate on GABAergic synaptic transmission","volume":"64","author":"Mtchedlishvili","year":"2003","journal-title":"Mol. Pharmacol."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib196","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1124\/mol.107.034058","article-title":"The neurosteroids dehydroepiandrosterone sulfate and pregnenolone sulfate inhibit the UNC-49 GABA receptor through a common set of residues","volume":"72","author":"Twede","year":"2007","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib197","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1038\/npp.2015.246","article-title":"5alpha-reductase inhibition prevents the luteal phase increase in plasma allopregnanolone levels and mitigates symptoms in women with premenstrual dysphoric disorder","volume":"41","author":"Martinez","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbrc.2024.150218_bib198","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nn1868","article-title":"Reversal of neurosteroid effects at alpha4beta2delta GABAA receptors triggers anxiety at puberty","volume":"10","author":"Shen","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib199","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2020.479646","article-title":"Steroid hormone sensitivity in reproductive mood disorders: on the role of the GABAA receptor complex and stress during hormonal transitions","volume":"7","author":"Schweizer-Schubert","year":"2021","journal-title":"Front. Med."},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib200","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1080\/09540261.2018.1553775","article-title":"Allopregnanolone and reproductive psychiatry: an overview","volume":"31","author":"McEvoy","year":"2019","journal-title":"Int. Rev. Psychiatr."},{"issue":"7","key":"10.1016\/j.bbrc.2024.150218_bib201","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1176\/ajp.155.7.910","article-title":"Effects of antidepressant treatment on neuroactive steroids in major depression","volume":"155","author":"Romeo","year":"1998","journal-title":"Am. J. Psychiatr."},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib202","doi-asserted-by":"crossref","first-page":"3239","DOI":"10.1073\/pnas.95.6.3239","article-title":"Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine","volume":"95","author":"Uzunova","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"23","key":"10.1016\/j.bbrc.2024.150218_bib203","doi-asserted-by":"crossref","first-page":"13512","DOI":"10.1073\/pnas.96.23.13512","article-title":"Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes","volume":"96","author":"Griffin","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib204","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/15622970009150572","article-title":"Effects of fluoxetine, indomethacine and placebo on 3 alpha, 5 alpha tetrahydroprogesterone (THP) plasma levels in uncomplicated alcohol withdrawal","volume":"1","author":"Romeo","year":"2000","journal-title":"World J. Biol. Psychiatr."},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib205","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1007\/s00213-005-0213-2","article-title":"Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake","volume":"186","author":"Pinna","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib206","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2018.7399","article-title":"Patterns in outpatient benzodiazepine prescribing in the United States","volume":"2","author":"Agarwal","year":"2019","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.bbrc.2024.150218_bib207","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1186\/s12889-020-08984-z","article-title":"Trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs in the health region of Lleida from 2002 to 2015","volume":"20","author":"Torres-Bondia","year":"2020","journal-title":"BMC Publ. Health"},{"key":"10.1016\/j.bbrc.2024.150218_bib208","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/978-981-32-9705-0_20","article-title":"Role of benzodiazepines in anxiety disorders","volume":"1191","author":"Balon","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib209","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1001\/jamapsychiatry.2014.2190","article-title":"Why are benzodiazepines not yet controlled substances?","volume":"72","author":"Moore","year":"2015","journal-title":"JAMA Psychiatr."},{"issue":"8","key":"10.1016\/j.bbrc.2024.150218_bib210","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1080\/14656566.2018.1472767","article-title":"Comparing the efficacy of benzodiazepines and serotonergic anti-depressants for adults with generalized anxiety disorder: a meta-analytic review","volume":"19","author":"Gomez","year":"2018","journal-title":"Expet Opin. Pharmacother."},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib211","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000353198","article-title":"Efficacy and tolerability of benzodiazepines versus antidepressants in anxiety disorders: a systematic review and meta-analysis","volume":"82","author":"Offidani","year":"2013","journal-title":"Psychother. Psychosom."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib212","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/YIC.0000000000000276","article-title":"Effectiveness and safety of long-term benzodiazepine use in anxiety disorders: a systematic review and meta-analysis","volume":"34","author":"Shinfuku","year":"2019","journal-title":"Int. Clin. Psychopharmacol."},{"issue":"11","key":"10.1016\/j.bbrc.2024.150218_bib213","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.4088\/JCP.v66n1109","article-title":"The selective GABA reuptake inhibitor tiagabine for the treatment of generalized anxiety disorder: results of a placebo-controlled study","volume":"66","author":"Psollack","year":"2005","journal-title":"J. Clin. Psychiatry"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib214","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/jcp.0b013e318059361a","article-title":"The role of anticonvulsant drugs in anxiety disorders: a critical review of the evidence","volume":"27","author":"Mula","year":"2007","journal-title":"J. Clin. Psychopharmacol."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib215","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1517\/13543784.2014.979283","article-title":"Pregabalin for the treatment of social anxiety disorder","volume":"24","author":"Kawalec","year":"2015","journal-title":"Expet Opin. Invest. Drugs"},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib216","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/YIC.0b013e3283491fd5","article-title":"Efficacy of pregabalin in preventing relapse in patients with generalized social anxiety disorder: results of a double-blind, placebo-controlled 26-week study","volume":"26","author":"Greist","year":"2011","journal-title":"Int. Clin. Psychopharmacol."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib217","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/YIC.0b013e32834519bd","article-title":"Efficacy of pregabalin in generalized social anxiety disorder: results of a double-blind, placebo-controlled, fixed-dose study","volume":"26","author":"Feltner","year":"2011","journal-title":"Int. Clin. Psychopharmacol."},{"issue":"8","key":"10.1016\/j.bbrc.2024.150218_bib218","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.sapharm.2018.06.018","article-title":"Reports of gabapentin and pregabalin abuse, misuse, dependence, or overdose: an analysis of the food and drug administration adverse events reporting system (FAERS)","volume":"15","author":"Evoy","year":"2019","journal-title":"Res. Soc. Adm. Pharm."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib219","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/cns.13115","article-title":"Pregabalin: a range of misuse-related unanswered questions","volume":"25","author":"Schifano","year":"2019","journal-title":"CNS Neurosci. Ther."},{"issue":"7","key":"10.1016\/j.bbrc.2024.150218_bib220","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/jat\/bkz036","article-title":"Misuse and mortality related to gabapentin and pregabalin are being under-estimated: a two-year post-mortem population study","volume":"43","author":"Nahar","year":"2019","journal-title":"J. Anal. Toxicol."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib221","doi-asserted-by":"crossref","first-page":"19r02465","DOI":"10.4088\/PCC.19r02465","article-title":"Effectiveness of gabapentin in reducing cravings and withdrawal in alcohol use disorder: a meta-analytic review","volume":"21","author":"Ahmed","year":"2019","journal-title":"Prim. Care Companion CNS Disord"},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib222","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1097\/00004714-200008000-00011","article-title":"Placebo-controlled study of gabapentin treatment of panic disorder","volume":"20","author":"Pande","year":"2000","journal-title":"J. Clin. Psychopharmacol."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib223","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1177\/0269881103017002006","article-title":"Effects of gabapentin on anxiety induced by simulated public speaking","volume":"17","author":"De-Paris","year":"2003","journal-title":"J. Psychopharmacol."},{"issue":"7","key":"10.1016\/j.bbrc.2024.150218_bib224","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/add.13324","article-title":"Gabapentin misuse, abuse and diversion: a systematic review","volume":"111","author":"Smith","year":"2016","journal-title":"Addiction"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib225","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1038\/s41380-021-01386-6","article-title":"Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: systematic review, meta-analysis, and rationale","volume":"27","author":"Hong","year":"2022","journal-title":"Mol. Psychiatr."},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib226","doi-asserted-by":"crossref","first-page":"123","DOI":"10.4088\/PCC.08l00641","article-title":"Gabapentin and tiagabine for social anxiety: a randomized, double-blind, crossover study of 8 adults","volume":"11","author":"Urbano","year":"2009","journal-title":"Prim. Care Companion J. Clin. Psychiatry"},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib227","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00213-005-2146-1","article-title":"Lamotrigine has an anxiolytic-like profile in the rat conditioned emotional response test of anxiety: a potential role for sodium channels?","volume":"180","author":"Mirza","year":"2005","journal-title":"Psychopharmacology"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib228","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/WNF.0b013e3181d4c1f6","article-title":"Lamotrigine administration in panic disorder with agoraphobia","volume":"33","author":"Masdrakis","year":"2010","journal-title":"Clin. Neuropharmacol."},{"issue":"19","key":"10.1016\/j.bbrc.2024.150218_bib229","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.2165\/00003495-200464190-00004","article-title":"Antiepileptic drugs in the treatment of anxiety disorders: role in therapy","volume":"64","author":"Van Ameringen","year":"2004","journal-title":"Drugs"},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib230","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.eurpsy.2007.08.001","article-title":"Valproate (depakine-chrono) in the acute treatment of outpatients with generalized anxiety disorder without psychiatric comorbidity: randomized, double-blind placebo-controlled study","volume":"23","author":"Aliyev","year":"2008","journal-title":"Eur. Psychiatr."},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib231","first-page":"169","article-title":"Valproic acid for the treatment of social anxiety disorder","volume":"18","author":"Kinrys","year":"2003","journal-title":"Int. Clin. Psychopharmacol."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib232","doi-asserted-by":"crossref","first-page":"627","DOI":"10.4088\/JCP.08m04949gre","article-title":"Levetiracetam in generalized social anxiety disorder: a double-blind, randomized controlled trial","volume":"71","author":"Stein","year":"2010","journal-title":"J. Clin. Psychiatry"},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib233","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1177\/0269881105056526","article-title":"Levetiracetam in social phobia: a placebo controlled pilot study","volume":"19","author":"Zhang","year":"2005","journal-title":"J. Psychopharmacol."},{"issue":"9","key":"10.1016\/j.bbrc.2024.150218_bib234","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nrd4075","article-title":"50 years of hurdles and hope in anxiolytic drug discovery","volume":"12","author":"Griebel","year":"2013","journal-title":"Nat. Rev. Drug Discov."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib235","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pharmthera.2009.09.001","article-title":"Preclinical and clinical pharmacology of the GABAA receptor alpha5 subtype-selective inverse agonist alpha5IA","volume":"125","author":"Atack","year":"2010","journal-title":"Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib236","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/JCP.0000000000000997","volume":"39","author":"Simen","year":"2019","journal-title":"J. Clin. Psychopharmacol."},{"issue":"10","key":"10.1016\/j.bbrc.2024.150218_bib237","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.biopsych.2019.12.013","article-title":"Cholinergic modulation of disorder-relevant neural circuits in generalized anxiety disorder","volume":"87","author":"Wise","year":"2020","journal-title":"Biol. Psychiatr."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib238","first-page":"84","article-title":"Novel benzodiazepine-like ligands with various anxiolytic, antidepressant, or pro-cognitive profiles","volume":"5","author":"Prevot","year":"2019","journal-title":"Mol. Neuropsychiatry"},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib239","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s40262-019-00801-0","article-title":"SAGE-217, a novel GABA(A) receptor positive allosteric modulator: clinical pharmacology and tolerability in randomized phase I dose-finding studies","volume":"59","author":"Hoffmann","year":"2020","journal-title":"Clin. Pharmacokinet."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib240","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1002\/ptr.6033","article-title":"Herbal medicine for depression and anxiety: a systematic review with assessment of potential psycho-oncologic relevance","volume":"32","author":"Yeung","year":"2018","journal-title":"Phytother Res."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib241","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/ptr.5940","article-title":"GABA-modulating phytomedicines for anxiety: a systematic review of preclinical and clinical evidence","volume":"32","author":"Savage","year":"2018","journal-title":"Phytother Res."},{"key":"10.1016\/j.bbrc.2024.150218_bib242","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110714","article-title":"Pleotropic effects of polyphenols in cardiovascular system","volume":"130","author":"Behl","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib243","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1007\/s10787-021-00826-7","article-title":"Role of vitamins and minerals as immunity boosters in COVID-19","volume":"29","author":"Kumar","year":"2021","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.bbrc.2024.150218_bib244","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.765485","article-title":"Effects of polyphenol supplementations on improving depression, anxiety, and quality of life in patients with depression","volume":"12","author":"Lin","year":"2021","journal-title":"Front. Psychiatr."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib245","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/JCP.0b013e3181ac935c","article-title":"A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder","volume":"29","author":"Amsterdam","year":"2009","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib246","first-page":"1","article-title":"The aqueous extract of Albizia adianthifolia leaves attenuates 6-hydroxydopamine-induced anxiety, depression and oxidative stress in rat amygdala","volume":"15","author":"Beppe","year":"2015","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.bbrc.2024.150218_bib247","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113630","article-title":"Flavonoid compounds isolated from Tibetan herbs, binding to GABAA receptor with anxiolytic property","volume":"267","author":"Liu","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib248","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.pbb.2012.08.017","article-title":"Antidepressant and anxiolytic effects of amentoflavone isolated from Cnestis ferruginea in mice","volume":"103","author":"Ishola","year":"2012","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.bbrc.2024.150218_bib249","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3329\/bjp.v12i4.33182","article-title":"Pharmacological validation of the anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal model","volume":"4","author":"Jawad","year":"2017","journal-title":"Bangladesh J. Pharmacol.12"},{"key":"10.1016\/j.bbrc.2024.150218_bib250","article-title":"Anxiolytic activity of ethanolic extract of seeds of Cuminum cyminum Linn in albino Wistar rats","volume":"8","author":"Harpreet","year":"2016","journal-title":"Int. J. Toxicol. Pharmacol. Res."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib251","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3109\/13880209.2012.749924","article-title":"Involvement of GABAergic system in regulation of the anxiolytic-and antidepressant-like effects of Scrophularia striata extract in rats","volume":"51","author":"Kosari-Nasab","year":"2013","journal-title":"Pharmaceut. Biol."},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib252","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.phymed.2008.12.020","article-title":"Kaempferol from the leaves of Apocynum venetum possesses anxiolytic activities in the elevated plus maze test in mice","volume":"16","author":"Grundmann","year":"2009","journal-title":"Phytomedicine"},{"issue":"4","key":"10.1016\/j.bbrc.2024.150218_bib253","article-title":"Plants and phytochemicals potentials in tackling anxiety: a systematic review","volume":"2","author":"Phootha","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bbrc.2024.150218_bib254","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1007\/BF02969279","article-title":"The protective effects of phenolic constituents from Gastrodia elata on the cytotoxicity induced by KCl and glutamate","volume":"29","author":"Huang","year":"2006","journal-title":"Arch Pharm. Res. (Seoul)"},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib255","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1248\/bpb.29.261","article-title":"Anxiolytic-like effects of Gastrodia elata and its phenolic constituents in mice","volume":"29","author":"Jung","year":"2006","journal-title":"Biol. Pharm. Bull."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib256","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jphs.2020.11.003","article-title":"A Japanese herbal medicine attenuates anxiety-like behavior through GABAA receptor and brain-derived neurotrophic factor expression in a rat model of premenstrual syndrome","volume":"145","author":"Iba","year":"2021","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.bbrc.2024.150218_bib257","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s11011-018-0188-4","article-title":"Hibiscus rosa sinensis mediate anxiolytic effect via modulation of ionotropic GABA-A receptors: possible mechanism of action","volume":"33","author":"Begum","year":"2018","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.bbrc.2024.150218_bib258","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s10571-014-0035-z","article-title":"Asparagus racemosus attenuates anxiety-like behavior in experimental animal models","volume":"34","author":"Garabadu","year":"2014","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.bbrc.2024.150218_bib259","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.pnpbp.2013.02.012","article-title":"Anxiolytic effects of Julibroside C1 isolated from Albizzia julibrissin in mice","volume":"44","author":"Jung","year":"2013","journal-title":"Prog. Neuro Psychopharmacol. Biol. Psychiatr."},{"issue":"15","key":"10.1016\/j.bbrc.2024.150218_bib260","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.2174\/1381612054021024","article-title":"GABAA receptor channel pharmacology","volume":"11","author":"Johnston","year":"2005","journal-title":"Curr. Pharmaceut. Des."},{"issue":"12","key":"10.1016\/j.bbrc.2024.150218_bib261","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1111\/jphp.13007","article-title":"Tannins from Terminalia chebula fruits attenuates GABA antagonist-induced anxiety-like behaviour via modulation of neurotransmitters","volume":"70","author":"Chandrasekhar","year":"2018","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib262","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s11418-016-1053-6","article-title":"Involvement of monoaminergic systems in anxiolytic and antidepressive activities of the standardized extract of Cocos nucifera L","volume":"71","author":"Lima","year":"2017","journal-title":"J. Nat. Med."},{"key":"10.1016\/j.bbrc.2024.150218_bib263","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2020.111766","article-title":"Bergamot essential oil attenuate aluminum-induced anxiety-like behavior through antioxidation, anti-inflammatory and GABA regulation in rats","volume":"145","author":"Cui","year":"2020","journal-title":"Food Chem. Toxicol."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib264","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13041-020-0560-2","article-title":"Scopoletin ameliorates anxiety-like behaviors in complete Freund's adjuvant-induced mouse model","volume":"13","author":"Luo","year":"2020","journal-title":"Mol. Brain"},{"issue":"3","key":"10.1016\/j.bbrc.2024.150218_bib265","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S1734-1140(11)70577-1","article-title":"Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels","volume":"63","author":"Gilhotra","year":"2011","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bbrc.2024.150218_bib266","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.brainres.2010.07.007","article-title":"GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice","volume":"1352","author":"Gilhotra","year":"2010","journal-title":"Brain Res."},{"issue":"5","key":"10.1016\/j.bbrc.2024.150218_bib267","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.pharep.2014.05.008","article-title":"Possible involvement of GABAergic and nitriergic systems for antianxiety-like activity of piperine in unstressed and stressed mice","volume":"66","author":"Gilhotra","year":"2014","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bbrc.2024.150218_bib268","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.physbeh.2015.11.038","article-title":"Diphenyl diselenide ameliorates monosodium glutamate induced anxiety-like behavior in rats by modulating hippocampal BDNF-Akt pathway and uptake of GABA and serotonin neurotransmitters","volume":"155","author":"Rosa","year":"2016","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbrc.2024.150218_bib269","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.pbb.2018.06.001","article-title":"Anxiolytic-like effect of pyridoxine in mice by elevated plus maze and light and dark box: evidence for the involvement of GABAergic and NO-sGC-cGMP pathway","volume":"173","author":"Walia","year":"2018","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.bbrc.2024.150218_bib270","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116142","article-title":"Antidepressant- and anxiolytic-like actions of Cajanus cajan seed extract mediated through monoaminergic, nitric oxide-cyclic GMP and GABAergic pathways","volume":"306","author":"Olubodun-Obadun","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib271","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S2221-6189(14)60030-5","article-title":"To evaluate anti-anxiety activity of thymol","volume":"3","author":"Bhandari","year":"2014","journal-title":"J. Acute. Dis."},{"issue":"22","key":"10.1016\/j.bbrc.2024.150218_bib272","doi-asserted-by":"crossref","first-page":"3596","DOI":"10.3390\/foods11223596","article-title":"Overcoming anxiety disorder by probiotic Lactiplantibacillus plantarum LZU-J-TSL6 through regulating intestinal homeostasis","volume":"11","author":"Liu","year":"2022","journal-title":"Foods"},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib273","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12906-020-03181-2","article-title":"A standardized polyherbal preparation POL-6 diminishes alcohol withdrawal anxiety by regulating Gabra1, Gabra2, Gabra3, Gabra4, Gabra5 gene expression of GABAA receptor signaling pathway in rats","volume":"21","author":"Sharma","year":"2021","journal-title":"BMC Complement. Med. Ther."},{"key":"10.1016\/j.bbrc.2024.150218_bib274","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2020.112952","article-title":"Chrysin reduces anxiety-like behavior through actions on GABAA receptors during metestrus-diestrus in the rat","volume":"397","author":"Rodr\u00edguez-Landa","year":"2021","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbrc.2024.150218_bib275","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.taap.2018.07.010","article-title":"Naringenin protects against oxido-inflammatory aberrations and altered tryptophan metabolism in olfactory bulbectomized-mice model of depression","volume":"355","author":"Bansal","year":"2018","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib276","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2019.106632","article-title":"Effect of rutin on anxiety-like behavior and activity of acetylcholinesterase isoforms in specific brain regions of pentylenetetrazol-treated mice","volume":"102","author":"Anesti","year":"2020","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.bbrc.2024.150218_bib277","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.1109458","article-title":"Epigallocatechin-3-gallate alleviates gestational stress-induced postpartum anxiety and depression-like behaviors in mice by downregulating semaphorin3A and promoting GSK3\u03b2 phosphorylation in the hippocampus","volume":"15","author":"Xu","year":"2023","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib278","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchemneu.2023.102313","article-title":"Quercetin mitigates depression-like behavior via the suppression of neuroinflammation and oxidative damage in corticosterone-induced mice","volume":"132","author":"Ge","year":"2023","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.bbrc.2024.150218_bib279","first-page":"4611","article-title":"Resveratrol ameliorates depressive disorder through the NETRIN1-mediated extracellular signal-regulated kinase\/cAMP signal transduction pathway","volume":"17","author":"Wang","year":"2018","journal-title":"Mol. Med. Rep."},{"issue":"16","key":"10.1016\/j.bbrc.2024.150218_bib280","doi-asserted-by":"crossref","first-page":"3314.","DOI":"10.3390\/nu14163314","article-title":"Luteolin-7-O-Glucuronide improves depression-like and stress coping behaviors in sleep deprivation stress model by activation of the BDNF signaling","volume":"14","author":"Ryu","year":"2022","journal-title":"Nutrients"},{"issue":"20","key":"10.1016\/j.bbrc.2024.150218_bib281","doi-asserted-by":"crossref","first-page":"4683.","DOI":"10.3390\/molecules25204683","article-title":"Kaempferol facilitated extinction learning in contextual fear conditioned rats via inhibition of fatty-acid amide hydrolase","volume":"25","author":"Ahmad","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.bbrc.2024.150218_bib282","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2020.616298","article-title":"Looking for novelty in an \u201cold\u201d receptor: recent advances toward our understanding of GABAARs and their implications in receptor pharmacology","volume":"14","author":"Castellano","year":"2021","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib283","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3389\/fendo.2011.00055","article-title":"Neurosteroids as neuromodulators in the treatment of anxiety disorders","volume":"2","author":"Longone","year":"2011","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.bbrc.2024.150218_bib284","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2019.100196","article-title":"Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond","volume":"11","author":"Zorumski","year":"2019","journal-title":"Neurobiol. Stress"},{"issue":"6","key":"10.1016\/j.bbrc.2024.150218_bib285","first-page":"675","article-title":"Effect of an acute intranasal aerosol dose of PH94B on social and performance anxiety in women with social anxiety disorder","volume":"171","author":"Liebowitz","year":"2014","journal-title":"Aust. J. Pharm."},{"issue":"12","key":"10.1016\/j.bbrc.2024.150218_bib286","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1002\/da.22546","article-title":"Effect of as-needed use of intranasal PH94B on social and performance anxiety in individuals with social anxiety disorder","volume":"33","author":"Liebowitz","year":"2016","journal-title":"Depress. Anxiety"},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib287","first-page":"91","article-title":"Combined pharmacotherapy and cognitive-behavioral therapy for anxiety disorders: medication effects, glucocorticoids, and attenuated treatment outcomes","volume":"17","author":"Otto","year":"2010","journal-title":"Clin. Psychol."},{"issue":"2","key":"10.1016\/j.bbrc.2024.150218_bib288","doi-asserted-by":"crossref","DOI":"10.1111\/jne.13062","article-title":"A role for deficits in GABAergic neurosteroids and their metabolites with NMDA receptor antagonist activity in the pathophysiology of posttraumatic stress disorder","volume":"34","author":"Rasmusson","year":"2022","journal-title":"J. Neuroendocrinol."},{"issue":"11","key":"10.1016\/j.bbrc.2024.150218_bib289","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1080\/1028415X.2018.1447296","article-title":"Effects of isoflavones on behavior, estradiol, glutamate, and GABA levels in intact middle-aged female rats","volume":"22","author":"Sandini","year":"2019","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150218_bib290","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2020.104895","article-title":"GABA-enriched teas as neuro-nutraceuticals","volume":"141","author":"Hinton","year":"2020","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bbrc.2024.150218_bib292","first-page":"969","article-title":"Anxiolytic Effect of Hydroethanolic Extract of Drymaria Cordata L Willd","volume":"47","author":"Barua","year":"2009","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.bbrc.2024.150218_bib294","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.exer.2012.10.005","article-title":"Blocking GABA(C) receptors increases light responsiveness of retinal ganglion cells in a rat model of retinitis pigmentosa","volume":"105","author":"Jensen","year":"2012","journal-title":"Exp. Eye Res."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib295","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/YIC.0000000000000147","article-title":"Pregabalin for generalized anxiety disorder: an updated systematic review and meta-analysis","volume":"32","author":"Generoso","year":"2017","journal-title":"Int. Clin. Psychopharmacol."},{"key":"10.1016\/j.bbrc.2024.150218_bib296","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s00441-017-2745-2","article-title":"Septo-hippocampal interaction","volume":"373","author":"Muller","year":"2018","journal-title":"Cell Tissue Res."},{"issue":"1","key":"10.1016\/j.bbrc.2024.150218_bib298","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s13041-021-00849-9","article-title":"Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain","volume":"14","author":"Shao","year":"2021","journal-title":"Mol. Brain"},{"issue":"11","key":"10.1016\/j.bbrc.2024.150218_bib299","doi-asserted-by":"crossref","first-page":"731","DOI":"10.2165\/00023210-200216110-00002","article-title":"Therapeutic potential of kava in the treatment of anxiety disorders","volume":"16","author":"Singh","year":"2002","journal-title":"CNS Drugs"},{"key":"10.1016\/j.bbrc.2024.150218_bib301","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1460-9568.2008.06319.x","article-title":"Types and synaptic connections of hippocampal inhibitory neurons reciprocally connected with the medial septum","volume":"28","author":"Takacs","year":"2008","journal-title":"Eur. J. Neurosci."},{"issue":"2\u20133","key":"10.1016\/j.bbrc.2024.150218_bib302","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1007\/s004240000412","article-title":"GABA(C) receptors in neuroendocrine gut cells: a new GABA-binding site in the gut","volume":"441","author":"Jansen","year":"2000","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.bbrc.2024.150218_bib303","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3389\/neuro.08.006.2010","article-title":"GABA(C) Receptors in the Lateral Amygdala: A Possible Novel Target for the Treatment of Fear and Anxiety Disorders?","volume":"4","author":"Cunha","year":"2010","journal-title":"Front. Behav. Neurosci."},{"issue":"11","key":"10.1016\/j.bbrc.2024.150218_bib304","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.4088\/JCP.v66n1109","article-title":"The selective GABA reuptake inhibitor tiagabine for the treatment of generalized anxiety disorder: results of a placebo-controlled study","volume":"66","author":"Pollack","year":"2005","journal-title":"J. Clin. Psychiatry."},{"key":"10.1016\/j.bbrc.2024.150218_bib305","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jep.2017.02.023","article-title":"Anxiolytic- and antidepressant-like effects of an aqueous extract of Tanacetum parthenium L. Schultz-Bip (Asteraceae) in mice","volume":"200","author":"C\u00e1rdenas","year":"2017","journal-title":"J. Ethnopharmacol."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X2400754X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X2400754X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T11:10:08Z","timestamp":1719054608000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X2400754X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":301,"alternative-id":["S0006291X2400754X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150218","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GABAergic implications in anxiety and related disorders","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150218","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"150218"}}