{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T05:55:48Z","timestamp":1782539748808,"version":"3.54.5"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"am","delay-in-days":280,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17909491"],"award-info":[{"award-number":["17909491"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["18950241"],"award-info":[{"award-number":["18950241"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.bbrc.2024.150342","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T06:50:24Z","timestamp":1720075824000},"page":"150342","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["IL-10 induces activated phenotypes of monocytes observed in virally-suppressed HIV-1-infected individuals"],"prefix":"10.1016","volume":"729","author":[{"given":"Naofumi","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5398-4205","authenticated-orcid":false,"given":"Youssef M.","family":"Eltalkhawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanako","family":"Nasu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3689-6596","authenticated-orcid":false,"given":"Randa A.","family":"Abdelnaser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Monde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara A.","family":"Habash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9163-1665","authenticated-orcid":false,"given":"Hesham","family":"Nasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masateru","family":"Hiyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takatsugu","family":"Ishimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Suzu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2024.150342_bib1","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.immuni.2013.10.001","article-title":"Systemic effects of inflammation on Health during chronic HIV infection","volume":"39","author":"Deeks","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.bbrc.2024.150342_bib2","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/B978-0-12-407707-2.00002-3","article-title":"Residual immune dysregulation syndrome in treated HIV infection","volume":"119","author":"Lederman","year":"2013","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib3","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1093\/infdis\/jiw275","article-title":"Immunologic biomarkers, morbidity, and mortality in treated HIV infection","volume":"214","author":"Hunt","year":"2016","journal-title":"JID (J. Infect. Dis.)"},{"key":"10.1016\/j.bbrc.2024.150342_bib4","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/infdis\/jix586","article-title":"Can biomarkers advance HIV research and care in the antiretroviral therapy era","volume":"217","author":"Justice","year":"2018","journal-title":"JID (J. Infect. Dis.)"},{"key":"10.1016\/j.bbrc.2024.150342_bib5","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1097\/QAD.0000000000000675","article-title":"The effect of short-course antiretroviral therapy initiated in primary HIV-1 infection on interleukin-6 and D-dimer levels","volume":"29","author":"Hamlyn","year":"2015","journal-title":"AIDS"},{"key":"10.1016\/j.bbrc.2024.150342_bib6","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1097\/QAD.0000000000001149","article-title":"Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy","volume":"30","author":"Hsu","year":"2016","journal-title":"AIDS"},{"key":"10.1016\/j.bbrc.2024.150342_bib7","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1093\/infdis\/jiw173","article-title":"Interleukin 6 is a stronger predictor of clinical events than high-sensitivity C-reactive protein or D-dimer during HIV infection","volume":"214","author":"Borges","year":"2016","journal-title":"JID (J. Infect. Dis.)"},{"key":"10.1016\/j.bbrc.2024.150342_bib8","doi-asserted-by":"crossref","DOI":"10.1182\/blood-2010-02-258558","article-title":"Nomenclature of monocytes and dendritic cells in blood","volume":"116","author":"Ziegler-Heitbrock","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2024.150342_bib9","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1002\/eji.1830251232","article-title":"CD14lowCD16high: a cytokine\u2010producing monocyte subset which expands during human immunodeficiency virus infection","volume":"25","author":"Thieblemont","year":"1995","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib10","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1093\/infdis\/jiu275","article-title":"Monocyte-activation phenotypes are associated with biomarkers of inflammation and coagulation in chronic HIV infection","volume":"210","author":"Wilson","year":"2014","journal-title":"JID (J. Infect. Dis.)"},{"key":"10.1016\/j.bbrc.2024.150342_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.820480","article-title":"Persistent inflammation and non-AIDS comorbidities during ART: coming of the age of monocytes","volume":"13","author":"Bai","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib12","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/infdis\/jir214","article-title":"Soluble CD163 made by monocyte\/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after antiretroviral therapy","volume":"204","author":"Burdo","year":"2011","journal-title":"JID (J. Infect. Dis.)"},{"key":"10.1016\/j.bbrc.2024.150342_bib13","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1001\/jama.2012.6698","article-title":"Arterial inflammation in patients with HIV","volume":"308","author":"Subramanian","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.bbrc.2024.150342_bib14","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1038\/nm1511","article-title":"Microbial translocation is a cause of systemic immune activation in chronic HIV infection","volume":"12","author":"Brenchley","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbrc.2024.150342_bib15","doi-asserted-by":"crossref","first-page":"4599","DOI":"10.1182\/blood-2012-05-433946","article-title":"Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome","volume":"120","author":"Funderburg","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2024.150342_bib16","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1093\/infdis\/jiq107","article-title":"Is microbial translocation a cause or consequence of HIV disease progression?","volume":"203","author":"Redd","year":"2011","journal-title":"JID (J. Infect. Dis.)"},{"key":"10.1016\/j.bbrc.2024.150342_bib17","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1097\/QAD.0b013e328351f756","article-title":"HIV infection induces age-related changes to monocytes and innate immune activation in young men that persist despite combination antiretroviral therapy","volume":"26","author":"Hearps","year":"2012","journal-title":"AIDS"},{"key":"10.1016\/j.bbrc.2024.150342_bib18","doi-asserted-by":"crossref","first-page":"2910","DOI":"10.1182\/blood.V85.10.2910.bloodjournal85102910","article-title":"CD16+ monocytes in patients with cancer: spontaneous elevation and pharmacologic induction by recombinant human macrophage colony-stimulating factor","volume":"85","author":"Saleh","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2024.150342_bib19","doi-asserted-by":"crossref","DOI":"10.1186\/s13075-016-1216-6","article-title":"CD14brightCD16+ intermediate monocytes are induced by interleukin-10 and positively correlate with disease activity in rheumatoid arthritis","volume":"19","author":"Tsukamoto","year":"2017","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbrc.2024.150342_bib20","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.ccell.2018.10.007","article-title":"PEGylated IL-10 (pegilodecakin) induces systemic immune activation, CD8+ T cell invigoration and polyclonal T cell expansion in cancer patients","volume":"34","author":"Naing","year":"2018","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbrc.2024.150342_bib21","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1038\/s41590-021-00940-2","article-title":"Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity","volume":"22","author":"Guo","year":"2021","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110565","article-title":"CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survival","volume":"38","author":"Yogev","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150342_bib23","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.ccell.2019.05.005","article-title":"Targeting tumors with IL-10 prevents dendritic cell-mediated CD8+ T cell apoptosis","volume":"35","author":"Qiao","year":"2019","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbrc.2024.150342_bib24","doi-asserted-by":"crossref","first-page":"970","DOI":"10.4049\/jimmunol.2200087","article-title":"Inhibitory and stimulatory effects of IL-32 on HIV-1 infection","volume":"209","author":"Nasser","year":"2022","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib25","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2014.233","article-title":"Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef","volume":"5","author":"Hashimoto","year":"2014","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbrc.2024.150342_bib26","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.chom.2009.06.009","article-title":"Massive secretion by T cells is caused by HIV nef in infected cells and by nef transfer to bystander cells","volume":"6","author":"Muratori","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.bbrc.2024.150342_bib27","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1600-0854.2009.01006.x","article-title":"HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells","volume":"11","author":"Lenassi","year":"2010","journal-title":"Traffic"},{"key":"10.1016\/j.bbrc.2024.150342_bib28","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1089\/aid.2009.0170","article-title":"HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals","volume":"27","author":"Raymond","year":"2011","journal-title":"AIDS Res. Hum. Retrovir."},{"key":"10.1016\/j.bbrc.2024.150342_bib29","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02344-17","article-title":"Nef secretion into extracellular vesicles or exosomes is conserved across human and simian immunodeficiency viruses","volume":"9","author":"McNamara","year":"2018","journal-title":"mBio"},{"key":"10.1016\/j.bbrc.2024.150342_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007907","article-title":"Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells","volume":"15","author":"Mukhamedova","year":"2019","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbrc.2024.150342_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111674","article-title":"Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells","volume":"41","author":"Dubrovsky","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150342_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.108779","article-title":"Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination","volume":"34","author":"Yasuda","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150342_bib33","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S1074-7613(00)80404-5","article-title":"Interleukin-10 down-regulates MHC class II \u03b1\u03b2 peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling","volume":"7","author":"Koppelman","year":"1997","journal-title":"Immunity"},{"key":"10.1016\/j.bbrc.2024.150342_bib34","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.4049\/jimmunol.1302821","article-title":"CCL2 shapes macrophage polarization by GM-CSF and M-CSF: identification of CCL2\/CCR2-dependent gene expression profile","volume":"192","author":"Sierra-Filardi","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib35","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev-immunol-031210-101312","article-title":"Regulation and functions of the IL-10 family of cytokines in inflammation and disease","volume":"29","author":"Ouyang","year":"2011","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib36","doi-asserted-by":"crossref","first-page":"16357","DOI":"10.1074\/jbc.271.27.16357","article-title":"Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine","volume":"271","author":"Crawley","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2024.150342_bib37","doi-asserted-by":"crossref","first-page":"584","DOI":"10.4049\/jimmunol.1401024","article-title":"Adenosine 5\u2032-monophosphate\u2013activated protein kinase regulates IL-10\u2013mediated anti-inflammatory signaling pathways in macrophages","volume":"194","author":"Zhu","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib38","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1046\/j.1365-2249.1999.00865.x","article-title":"IL-10 in HIV infection: increasing serum IL-10 levels with disease progression--down-regulatory effect of potent anti-retroviral therapy","volume":"116","author":"Stylianou","year":"1999","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib39","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1182\/blood-2008-12-191296","article-title":"IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells","volume":"114","author":"Brockman","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.bbrc.2024.150342_bib40","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.2147\/TCRM.S117980","article-title":"Inflammation-modulating cytokine profile and lipid interaction in HIV-related risk factors for cardiovascular diseases","volume":"12","author":"Gori","year":"2016","journal-title":"Therapeut. Clin. Risk Manag."},{"key":"10.1016\/j.bbrc.2024.150342_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2019.154839","article-title":"Impact of ART on dynamics of growth factors and cytokines in primary HIV infection","volume":"125","author":"Bordoni","year":"2020","journal-title":"Cytokine"},{"key":"10.1016\/j.bbrc.2024.150342_bib42","doi-asserted-by":"crossref","first-page":"e523","DOI":"10.1016\/j.ddtec.2013.07.002","article-title":"Small molecule inhibitors of the HIV-1 virulence factor, Nef","volume":"10","author":"Smithgall","year":"2013","journal-title":"Drug Discov. Today Technol."},{"key":"10.1016\/j.bbrc.2024.150342_bib43","first-page":"1229","article-title":"HIV nef promotes expression of B-lymphocyte stimulator by blood dendritic cells during HIV infection in humans","volume":"211","author":"Chagnon-Choquet","year":"2015","journal-title":"JID (J. Infect. Dis.)"},{"key":"10.1016\/j.bbrc.2024.150342_bib44","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1089\/aid.2013.0250","article-title":"Intracellular Nef detected in peripheral blood mononuclear cells from HIV patients","volume":"31","author":"Wang","year":"2015","journal-title":"AIDS Res. Hum. Retrovir."},{"key":"10.1016\/j.bbrc.2024.150342_bib45","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-08736-x","article-title":"HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy","volume":"7","author":"Gupta","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2024.150342_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0191613","article-title":"Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA","volume":"13","author":"Ferdin","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2024.150342_bib47","doi-asserted-by":"crossref","first-page":"15757","DOI":"10.1074\/jbc.M510714200","article-title":"Constitutive receptor-independent low density lipoprotein uptake and cholesterol accumulation by macrophages differentiated from human monocytes with macrophage-colony-stimulating factor (M-CSF)","volume":"281","author":"Zhao","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2024.150342_bib48","first-page":"342","article-title":"Beyond stem cells: self-renewal of differentiated macrophages","volume":"1979","author":"Sieweke","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2024.150342_bib49","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/ni.3341","article-title":"The development and maintenance of resident macrophages","volume":"17","author":"Perdiguero","year":"2016","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib50","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.immuni.2016.02.024","article-title":"Tissue-resident macrophage ontogeny and homeostasis","volume":"44","author":"Ginhoux","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.bbrc.2024.150342_bib51","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.4049\/jimmunol.1402307","article-title":"Chronic psoriatic skin inflammation leads to increased monocyte adhesion and aggregation","volume":"195","author":"Golden","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib52","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/1097-0320(20001201)41:4<279::AID-CYTO6>3.0.CO;2-B","article-title":"Diverging pathways for lipopolysaccharide and CD14 in human monocytes","volume":"41","author":"Antal-Szalm\u00e1s","year":"2000","journal-title":"Cytometry"},{"key":"10.1016\/j.bbrc.2024.150342_bib53","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20190418","article-title":"Biology and therapeutic potential of interleukin-10","volume":"217","author":"Saraiva","year":"2020","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbrc.2024.150342_bib54","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.139834","article-title":"Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease","volume":"5","author":"Zhao","year":"2020","journal-title":"JCI Insight"},{"key":"10.1016\/j.bbrc.2024.150342_bib55","doi-asserted-by":"crossref","DOI":"10.1186\/s13023-021-01973-4","article-title":"Increased levels of serum interleukin-10 are associated with poor outcome in adult hemophagocytic lymphohistiocytosis patients","volume":"16","author":"Zhou","year":"2021","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.bbrc.2024.150342_bib56","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/j.jaci.2022.06.017","article-title":"Excessive IL-10 and IL-18 trigger hemophagocytic lymphohistiocytosis\u2013like hyperinflammation and enhanced myelopoiesis","volume":"150","author":"Tang","year":"2022","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.bbrc.2024.150342_bib57","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1165\/rcmb.2018-0089OC","article-title":"HIV-Nef protein persists in the lungs of aviremic patients with HIV and induces endothelial cell death","volume":"60","author":"Chelvanambi","year":"2019","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbrc.2024.150342_bib58","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1006\/cyto.2000.0741","article-title":"Monocytes are target cells for IL-10 induction by HIV-1 Nef protein","volume":"12","author":"Tangsinmankong","year":"2000","journal-title":"Cytokine"},{"key":"10.1016\/j.bbrc.2024.150342_bib59","doi-asserted-by":"crossref","DOI":"10.1172\/JCI155251","article-title":"Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy","volume":"132","author":"Harper","year":"2022","journal-title":"J. Clin. Invest."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24008787?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24008787?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T04:28:44Z","timestamp":1730867324000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X24008787"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":59,"alternative-id":["S0006291X24008787"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150342","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"IL-10 induces activated phenotypes of monocytes observed in virally-suppressed HIV-1-infected individuals","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150342","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"150342"}}