{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T14:40:41Z","timestamp":1779288041506,"version":"3.51.4"},"reference-count":89,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013306","name":"NISER","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013306","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001502","name":"Department of Atomic Energy, Government of India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001502","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.bbrc.2024.150518","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T01:29:53Z","timestamp":1723080593000},"page":"150518","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Role of gut microbial-derived metabolites and other select agents on adipocyte browning"],"prefix":"10.1016","volume":"737","author":[{"given":"Akankshya","family":"Nayak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9648-9856","authenticated-orcid":false,"given":"Swati Sagarika","family":"Panda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8468-2584","authenticated-orcid":false,"given":"Isha","family":"Dwivedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivani","family":"Meena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4927-7812","authenticated-orcid":false,"given":"Palok","family":"Aich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2024.150518_bib1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.4082\/kjfm.20.0165","article-title":"Sedentary lifestyle: overview of updated evidence of potential health risks","volume":"41","author":"Park","year":"2020","journal-title":"Korean J Fam Med"},{"key":"10.1016\/j.bbrc.2024.150518_bib2","article-title":"Lifestyle modification in the management of the metabolic syndrome: achievements and challenges","volume":"373","author":"Giulio Marchesini","year":"2010","journal-title":"Diabetes Metab Syndr Obes"},{"key":"10.1016\/j.bbrc.2024.150518_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.physbeh.2017.03.040","article-title":"Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet","volume":"176","author":"Bunney","year":"2017","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbrc.2024.150518_bib4","doi-asserted-by":"crossref","DOI":"10.1186\/s12937-015-0045-9","article-title":"Association between dietary patterns and metabolic syndrome in individuals with normal weight: a cross-sectional study","volume":"14","author":"Suliga","year":"2015","journal-title":"Nutr. J."},{"key":"10.1016\/j.bbrc.2024.150518_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.focha.2023.100335","article-title":"Metabolic syndrome: risk factors, diagnosis, pathogenesis, and management with natural approaches","volume":"3","author":"Mohamed","year":"2023","journal-title":"Food Chemistry Advances"},{"key":"10.1016\/j.bbrc.2024.150518_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/metabo13040488","article-title":"A systematic review on the association between obesity and mood disorders and the role of gut microbiota","volume":"13","author":"Panda","year":"2023","journal-title":"Metabolites"},{"key":"10.1016\/j.bbrc.2024.150518_bib7","doi-asserted-by":"crossref","DOI":"10.1530\/JOE-22-0111","article-title":"The gut microbiome: a core regulator of metabolism","volume":"256","author":"Fujisaka","year":"2023","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.bbrc.2024.150518_bib8","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1177\/1756283X13482996","article-title":"Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ","volume":"6","author":"Guinane","year":"2013","journal-title":"Therap Adv Gastroenterol"},{"key":"10.1016\/j.bbrc.2024.150518_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aninu.2020.11.005","article-title":"Relationship between gut microbiota and host-metabolism: emphasis on hormones related to reproductive function","volume":"7","author":"Hussain","year":"2021","journal-title":"Animal Nutrition"},{"key":"10.1016\/j.bbrc.2024.150518_bib10","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.bbalip.2018.05.013","article-title":"Brown and beige fat: from molecules to physiology and pathophysiology","volume":"1864","author":"Carobbio","year":"2019","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbrc.2024.150518_bib11","doi-asserted-by":"crossref","first-page":"R77","DOI":"10.1530\/JOE-16-0211","article-title":"Adipose tissue in control of metabolism","volume":"231","author":"Luo","year":"2016","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.bbrc.2024.150518_bib12","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/MOP.0b013e32833a8d6e","article-title":"The role and importance of brown adipose tissue in energy homeostasis","volume":"22","author":"Cypess","year":"2010","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.bbrc.2024.150518_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122473","article-title":"Antibiotic induced adipose tissue browning in C57BL\/6 mice: an association with the metabolic profile and the gut microbiota","volume":"340","author":"Panda","year":"2024","journal-title":"Life Sci."},{"key":"10.1016\/j.bbrc.2024.150518_bib14","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1016\/j.celrep.2019.02.015","article-title":"Microbiota depletion impairs thermogenesis of Brown adipose tissue and browning of white adipose tissue","volume":"26","author":"Li","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150518_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/metabo11080531","article-title":"The role of gut microbiota and its produced metabolites in obesity, dyslipidemia, adipocyte dysfunction, and its interventions","volume":"11","author":"Zwartjes","year":"2021","journal-title":"Metabolites"},{"key":"10.1016\/j.bbrc.2024.150518_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2023.105488","article-title":"Short chain fatty acids increase fat oxidation and promote browning through \u03b23-adrenergic receptor\/AMP-activated protein kinase \u03b1 signaling pathway in 3T3-L1 adipocytes","volume":"103","author":"Zhang","year":"2023","journal-title":"J. Funct.Foods"},{"key":"10.1016\/j.bbrc.2024.150518_bib17","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1136\/gutjnl-2020-323071","article-title":"Gut microbiota-derived metabolites as central regulators in metabolic disorders","volume":"70","author":"Agus","year":"2021","journal-title":"Gut"},{"key":"10.1016\/j.bbrc.2024.150518_bib18","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1471-0366.2011.00323.x","article-title":"The New Peasantries. Struggles for Autonomy and Sustainability in an Era of Empire and Globalization - By Jan Douwe van der Ploeg","volume":"11","author":"Mollinga","year":"2011","journal-title":"J. Agrar. Change"},{"key":"10.1016\/j.bbrc.2024.150518_bib19","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1080\/03066150.2013.876997","article-title":"Peasant-driven agricultural growth and food sovereignty","volume":"41","author":"van der Ploeg","year":"2014","journal-title":"J. Peasant Stud."},{"key":"10.1016\/j.bbrc.2024.150518_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119538","article-title":"Effects of two potential probiotic Lactobacillus bacteria on adipogenesis in vitro","volume":"278","author":"Guha","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.bbrc.2024.150518_bib21","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s11306-014-0677-3","article-title":"Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals","volume":"11","author":"Bjerrum","year":"2015","journal-title":"Metabolomics"},{"key":"10.1016\/j.bbrc.2024.150518_bib22","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/iub.1750","article-title":"L-rhamnose induces browning in 3T3-L1 white adipocytes and activates HIB1B brown adipocytes","volume":"70","author":"Choi","year":"2018","journal-title":"IUBMB Life"},{"key":"10.1016\/j.bbrc.2024.150518_bib23","article-title":"Ginsenoside Rg3 induces browning of 3T3-L1 adipocytes by activating AMPK signaling","volume":"12","author":"Kim","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.bbrc.2024.150518_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0264400","article-title":"Differential colitis susceptibility of Th1- and Th2-biased mice: a multi-omics approach","volume":"17","author":"Mukhopadhyay","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2024.150518_bib25","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1111\/ejn.15972","article-title":"Effects of constant darkness on behaviour and physiology of male and female mice","volume":"57","author":"Singh","year":"2023","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150518_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.bj.2022.03.004","article-title":"Postnatal intestinal mucosa and gut microbial composition develop hand in hand: a mouse study","volume":"46","author":"Pandey","year":"2023","journal-title":"Biomed. J."},{"key":"10.1016\/j.bbrc.2024.150518_bib27","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.neuroscience.2023.03.016","article-title":"Sex and time: important variables for understanding the impact of constant darkness on behavior, brain, and physiology","volume":"519","author":"Singh","year":"2023","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbrc.2024.150518_bib28","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/nmeth.3393","article-title":"MS-DIAL: data-independent MS\/MS deconvolution for comprehensive metabolome analysis","volume":"12","author":"Tsugawa","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbrc.2024.150518_bib29","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software Environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res."},{"key":"10.1016\/j.bbrc.2024.150518_bib30","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkae253","article-title":"MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation","author":"Pang","year":"2024","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbrc.2024.150518_bib31","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms2537","article-title":"De novo lipogenesis in human fat and liver is linked to ChREBP-\u03b2 and metabolic health","volume":"4","author":"Eissing","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2024.150518_bib32","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1002\/cphy.c170001","article-title":"Brown and beige adipose tissues in health and disease","volume":"7","author":"Rui","year":"2017","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.bbrc.2024.150518_bib33","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.cell.2010.02.043","article-title":"Anti-inflammatory agents: present and future","volume":"140","author":"Dinarello","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2024.150518_bib34","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8416763","article-title":"Oxidative stress: harms and benefits for human health","volume":"2017","author":"Pizzino","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.bbrc.2024.150518_bib35","doi-asserted-by":"crossref","DOI":"10.1017\/S003358351600007X","article-title":"Bridging the gap between in vitro and in vivo RNA folding","volume":"49","author":"Leamy","year":"2016","journal-title":"Q. Rev. Biophys."},{"key":"10.1016\/j.bbrc.2024.150518_bib36","series-title":"Methods in Molecular Biology","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/978-1-4939-8994-2_25","article-title":"The use of 3T3-L1 murine preadipocytes as a model of adipogenesis","author":"Cave","year":"2019"},{"key":"10.1016\/j.bbrc.2024.150518_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/foods12234285","article-title":"Succinate enhances lipolysis and decreases adipocytes size in both subcutaneous and visceral adipose tissue from high-fat-diet-fed obese mice","volume":"12","author":"Ji","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.bbrc.2024.150518_bib38","doi-asserted-by":"crossref","first-page":"326","DOI":"10.2337\/db22-0552","article-title":"Rhamnose displays an anti-obesity effect through stimulation of adipose dopamine receptors and thermogenesis","volume":"72","author":"Lv","year":"2023","journal-title":"Diabetes"},{"key":"10.1016\/j.bbrc.2024.150518_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics14061192","article-title":"Ginsenoside compound K protects against obesity through pharmacological targeting of glucocorticoid receptor to activate lipophagy and lipid metabolism","volume":"14","author":"Yang","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.bbrc.2024.150518_bib40","doi-asserted-by":"crossref","DOI":"10.1186\/s40170-016-0163-7","article-title":"Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration","volume":"5","author":"Balaban","year":"2017","journal-title":"Cancer Metabol."},{"key":"10.1016\/j.bbrc.2024.150518_bib41","doi-asserted-by":"crossref","DOI":"10.1186\/s12986-016-0081-2","article-title":"Evaluation of markers of beige adipocytes in white adipose tissue of the mouse","volume":"13","author":"Garcia","year":"2016","journal-title":"Nutr. Metab."},{"key":"10.1016\/j.bbrc.2024.150518_bib42","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.bbalip.2018.05.004","article-title":"Development, activation, and therapeutic potential of thermogenic adipocytes","volume":"1864","author":"Emont","year":"2019","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbrc.2024.150518_bib43","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3008490","article-title":"ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes","volume":"6","author":"Ussar","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bbrc.2024.150518_bib44","article-title":"Ginsenoside Rg3, enriched in red ginseng extract, improves lipopolysaccharides-induced suppression of brown and beige adipose thermogenesis with mitochondrial activation","volume":"14","author":"Feng","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2024.150518_bib45","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231911818","article-title":"Spermine suppresses adipocyte differentiation and exerts anti-obesity effects in vitro and in vivo","volume":"23","author":"Nakatani","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2024.150518_bib46","article-title":"The mechanism underlying the influence of indole-3-propionic acid: a relevance to metabolic disorders","volume":"13","author":"Zhang","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.bbrc.2024.150518_bib47","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24050923","article-title":"The role of tocotrienol in protecting against metabolic diseases","volume":"24","author":"Pang","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.bbrc.2024.150518_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153264","article-title":"Effects of 23-epi-26-deoxyactein on adipogenesis in 3T3-L1 preadipocytes and diet-induced obesity in C57BL\/6 mice","volume":"76","author":"Yuan","year":"2020","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bbrc.2024.150518_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2020.111487","article-title":"Phthalate exposure causes browning-like effects on adipocytes in vitro and in vivo","volume":"142","author":"Hsu","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.bbrc.2024.150518_bib50","series-title":"Encyclopedia of Toxicology","first-page":"928","article-title":"Phthalates","author":"Saeidnia","year":"2014"},{"key":"10.1016\/j.bbrc.2024.150518_bib51","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.7150\/ijbs.4575","article-title":"Rhein protects against obesity and related metabolic disorders through liver X receptor-mediated uncoupling protein 1 upregulation in brown adipose tissue","volume":"8","author":"Sheng","year":"2012","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.bbrc.2024.150518_bib52","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.celrep.2016.12.062","article-title":"Brown adipogenic reprogramming induced by a small molecule","volume":"18","author":"Nie","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150518_bib53","article-title":"M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1","volume":"15","author":"Wu","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2024.150518_bib54","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/nature13816","article-title":"Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors","volume":"516","author":"Gnad","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2024.150518_bib55","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-24540-8","article-title":"Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice","volume":"12","author":"Guo","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2024.150518_bib56","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/joim.12803","article-title":"Inflammation of brown\/beige adipose tissues in obesity and metabolic disease","volume":"284","author":"Villarroya","year":"2018","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.bbrc.2024.150518_bib57","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8603164","article-title":"Role of uric acid metabolism-related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and nonalcoholic steatohepatitis","volume":"2016","author":"Kushiyama","year":"2016","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.bbrc.2024.150518_bib58","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.00852","article-title":"Extracellular purine metabolism is the Switchboard of immunosuppressive macrophages and a novel target to treat diseases with macrophage imbalances","volume":"9","author":"Ohradanova-Repic","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbrc.2024.150518_bib59","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.tcb.2023.04.007","article-title":"Inosine: novel activator of brown adipose tissue and energy homeostasis","volume":"34","author":"Pfeifer","year":"2024","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bbrc.2024.150518_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102834","article-title":"Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop","volume":"65","author":"Takeda","year":"2023","journal-title":"Redox Biol."},{"key":"10.1016\/j.bbrc.2024.150518_bib61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12013-009-9054-7","article-title":"Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms","volume":"55","author":"Battin","year":"2009","journal-title":"Cell Biochem. Biophys."},{"key":"10.1016\/j.bbrc.2024.150518_bib62","article-title":"Hydrogen sulfide in the adipose tissue-physiology, pathology and a target for pharmacotherapy","volume":"22","author":"Be\u0142towski","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.bbrc.2024.150518_bib63","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1002\/mnfr.201500915","article-title":"Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization","volume":"60","author":"Zhang","year":"2016","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.bbrc.2024.150518_bib64","unstructured":"T. Hamaoka, X. Fu, S. Tomonaga, O. Hashimoto, M. Murakami, M. Funaba, Stimulation of uncoupling protein 1 expression by \u03b2-alanine in brown adipocytes, n.d. www.editage.com."},{"key":"10.1016\/j.bbrc.2024.150518_bib65","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201800536","article-title":"Taurine is involved in energy metabolism in muscles, adipose tissue, and the liver","volume":"63","author":"Wen","year":"2019","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.bbrc.2024.150518_bib66","doi-asserted-by":"crossref","first-page":"15014","DOI":"10.1074\/jbc.RA119.009936","article-title":"Taurine-mediated browning of white adipose tissue is involved in its anti-obesity effect in mice","volume":"294","author":"Guo","year":"2019","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2024.150518_bib67","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00726-012-1361-4","article-title":"Taurine and inflammatory diseases","volume":"46","author":"Marcinkiewicz","year":"2014","journal-title":"Amino Acids"},{"key":"10.1016\/j.bbrc.2024.150518_bib68","doi-asserted-by":"crossref","DOI":"10.3390\/nu8020090","article-title":"Myricetin: a dietary molecule with diverse biological activities","volume":"8","author":"Semwal","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.bbrc.2024.150518_bib69","series-title":"Kniga Puteshestvii Po Imperii","author":"Bitov","year":"2000"},{"key":"10.1016\/j.bbrc.2024.150518_bib70","article-title":"Regulation of obesity and metabolic complications by gamma and delta tocotrienols","volume":"21","author":"Zhao","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.bbrc.2024.150518_bib71","doi-asserted-by":"crossref","first-page":"11410","DOI":"10.1021\/jf401635w","article-title":"Dietary supplementation with (-)-epigallocatechin-3-gallate reduces inflammatory response in adipose tissue of non-obese type 2 diabetic Goto-Kakizaki (GK) rats","volume":"61","author":"Uchiyama","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbrc.2024.150518_bib72","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-023-39118-9","article-title":"Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions","volume":"14","author":"Fan","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2024.150518_bib73","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1472-8206.2012.01040.x","article-title":"Antidepressant-like activity of gallic acid in mice subjected to unpredictable chronic mild stress","volume":"27","author":"Chhillar","year":"2013","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150518_bib74","first-page":"1388","article-title":"Vanillic acid attenuates obesity via activation of the AMPK pathway and thermogenic factors in vivo and in vitro","volume":"32","author":"Jung","year":"2018","journal-title":"FASEB (Fed. Am. Soc. Exp. Biol.) J."},{"key":"10.1016\/j.bbrc.2024.150518_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2022.102456","article-title":"Metabolomics reveals inosine 5\u2032-monophosphate is increased during mice adipocyte browning","volume":"298","author":"Takahashi","year":"2022","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2024.150518_bib76","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1017\/S000711451900148X","article-title":"Functional differences between L- and D-carnitine in metabolic regulation evaluated using a low-carnitine Nile tilapia model","volume":"122","author":"Li","year":"2019","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.bbrc.2024.150518_bib77","doi-asserted-by":"crossref","first-page":"389S","DOI":"10.1080\/07315724.2007.10719627","article-title":"The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study","volume":"26","author":"Boschmann","year":"2007","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.bbrc.2024.150518_bib78","doi-asserted-by":"crossref","DOI":"10.29219\/fnr.v66.7680","article-title":"Dietary adenosine 5\u2019-monophosphate supplementation increases food intake and remodels energy expenditure in mice","volume":"66","author":"Wu","year":"2022","journal-title":"Food Nutr. Res."},{"key":"10.1016\/j.bbrc.2024.150518_bib79","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.numecd.2018.12.001","article-title":"Betulinic acid inhibits high-fat diet-induced obesity and improves energy balance by activating AMPK","volume":"29","author":"Kim","year":"2019","journal-title":"Nutr. Metabol. Cardiovasc. Dis."},{"key":"10.1016\/j.bbrc.2024.150518_bib80","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2018.00282","article-title":"3,5-diiodo-L-thyronine increases glucose consumption in cardiomyoblasts without affecting the contractile performance in rat heart","volume":"9","author":"Sacripanti","year":"2018","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.bbrc.2024.150518_bib81","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2020.104011","article-title":"Effects of piperine on lipid metabolism in high-fat diet induced obese mice","volume":"71","author":"Du","year":"2020","journal-title":"J. Funct.Foods"},{"key":"10.1016\/j.bbrc.2024.150518_bib82","doi-asserted-by":"crossref","DOI":"10.3390\/molecules21101305","article-title":"Beneficial effects of tea and the green tea catechin epigallocatechin-3-gallate on obesity","volume":"21","author":"Suzuki","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.bbrc.2024.150518_bib83","article-title":"Okadaic acid, a bioactive fatty acid from Halichondria okadai, stimulates lipolysis in rat adipocytes: the pivotal role of perilipin translocation","volume":"2013","author":"Chang","year":"2013","journal-title":"Evid. base Compl. Alternative Med."},{"key":"10.1016\/j.bbrc.2024.150518_bib84","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.pharmthera.2013.06.001","article-title":"Regulation of metabolism by cGMP","volume":"140","author":"Pfeifer","year":"2013","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbrc.2024.150518_bib85","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0020644","article-title":"Beta-carotene reduces body adiposity of mice via BCMO1","volume":"6","author":"Amengual","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2024.150518_bib86","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222111738","article-title":"Chenodeoxycholic acid has non-thermogenic, mitodynamic anti-obesity effects in an in vitro crispr\/cas9 model of bile acid receptor tgr5 knockdown","volume":"22","author":"Teodoro","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2024.150518_bib87","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.3390\/md13052732","article-title":"Anti-obese effect of glucosamine and chitosan oligosaccharide in high-fat diet-induced obese rats","volume":"13","author":"Huang","year":"2015","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.bbrc.2024.150518_bib88","doi-asserted-by":"crossref","DOI":"10.1186\/s13063-019-3998-8","article-title":"Effects of lutein supplementation on inflammatory biomarkers and metabolic risk factors in adults with central obesity: study protocol for a randomised controlled study","volume":"21","author":"Zhou","year":"2020","journal-title":"Trials"},{"key":"10.1016\/j.bbrc.2024.150518_bib89","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s12325-020-01602-9","article-title":"The effects of acarbose on non-diabetic overweight and obese patients: a meta-analysis","volume":"38","author":"Yu","year":"2021","journal-title":"Adv. Ther."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24010544?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24010544?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T21:09:46Z","timestamp":1739221786000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X24010544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":89,"alternative-id":["S0006291X24010544"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150518","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of gut microbial-derived metabolites and other select agents on adipocyte browning","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150518","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"150518"}}