{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T06:42:30Z","timestamp":1782542550543,"version":"3.54.5"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T00:00:00Z","timestamp":1723680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.bbrc.2024.150558","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T06:14:41Z","timestamp":1723702481000},"page":"150558","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Sulindac prevents increased mitochondrial VDAC1 expression and cell surface mistargeting induced by pathological conditions in retinal cells"],"prefix":"10.1016","volume":"739","author":[{"given":"Mohammad","family":"Tariq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3443-4539","authenticated-orcid":false,"given":"Marie","family":"Sj\u00f6gren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6120-3539","authenticated-orcid":false,"given":"Albert","family":"Salehi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2024.150558_bib1","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.2337\/dc15-2171","article-title":"Loss expert group of the global burden of disease, global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 1990 to 2010","volume":"39","author":"Leasher","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1016\/j.bbrc.2024.150558_bib2","article-title":"Diabetic retinopathy","volume":"2","author":"Wong","year":"2016","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.bbrc.2024.150558_bib3","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-20243-2","article-title":"Regulation of serine palmitoyl-transferase and Rac1-Nox2 signaling in diabetic retinopathy","volume":"12","author":"Alka","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2024.150558_bib4","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1592\/phco.29.2.182","article-title":"Diabetic retinopathy: current management and experimental therapeutic targets","volume":"29","author":"Ali","year":"2009","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.bbrc.2024.150558_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1749-6632.1998.tb10102.x","article-title":"Morphogenesis of the retinal pigment epithelium: toward understanding retinal degenerative diseases","volume":"857","author":"Marmorstein","year":"1998","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbrc.2024.150558_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21082949","article-title":"Crocetin prevents RPE cells from oxidative stress through protection of cellular metabolic function and activation of ERK1\/2","volume":"21","author":"Karimi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2024.150558_bib7","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.preteyeres.2011.06.002","article-title":"Integration of tight junctions and claudins with the barrier functions of the retinal pigment epithelium","volume":"30","author":"Rizzolo","year":"2011","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.bbrc.2024.150558_bib8","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1023\/A:1002136712070","article-title":"Cellular mechanisms of blood-retinal barrier dysfunction in macular edema","volume":"97","author":"Vinores","year":"1999","journal-title":"Doc. Ophthalmol."},{"key":"10.1016\/j.bbrc.2024.150558_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100858","article-title":"Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration","volume":"79","author":"Kaarniranta","year":"2020","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.bbrc.2024.150558_bib10","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.4103\/1673-5374.147919","article-title":"Sulindac for stroke treatment: neuroprotective mechanism and therapy","volume":"9","author":"Modi","year":"2014","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.bbrc.2024.150558_bib11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.exer.2018.10.009","article-title":"Rapid differentiation of the human RPE cell line, ARPE-19, induced by nicotinamide","volume":"179","author":"Hazim","year":"2019","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.bbrc.2024.150558_bib12","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1006\/bbrc.1995.2477","article-title":"Transforming growth factor-beta inhibits the cytokine-mediated expression of the inducible nitric oxide synthase mRNA in human retinal pigment epithelial cells","volume":"215","author":"Kutty","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2024.150558_bib13","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/s41419-022-04755-3","article-title":"VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway","volume":"13","author":"de Sousa","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbrc.2024.150558_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fragi.2022.926627","article-title":"Role of mitochondria in retinal pigment epithelial aging and degeneration","volume":"3","author":"Tong","year":"2022","journal-title":"Front. Aging"},{"key":"10.1016\/j.bbrc.2024.150558_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/biom11010107","article-title":"Renaissance of VDAC: new insights on a protein family at the interface between mitochondria and cytosol","volume":"11","author":"De Pinto","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.bbrc.2024.150558_bib16","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.cmet.2018.09.008","article-title":"Preserving insulin secretion in diabetes by inhibiting VDAC1 overexpression and surface translocation in beta cells","volume":"29","author":"Zhang","year":"2019","journal-title":"Cell Metabol."},{"key":"10.1016\/j.bbrc.2024.150558_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108640","article-title":"VDAC1 regulates mitophagy in NLRP3 inflammasome activation in retinal capillary endothelial cells under high-glucose conditions","volume":"209","author":"Xie","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.bbrc.2024.150558_bib18","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1007\/s00424-019-02262-7","article-title":"The functional impact of G protein-coupled receptor 142 (Gpr142) on pancreatic beta-cell in rodent","volume":"471","author":"Al-Amily","year":"2019","journal-title":"Pfl\u00fcgers Archiv"},{"key":"10.1016\/j.bbrc.2024.150558_bib19","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1902\/jop.2008.080246","article-title":"The role of inflammatory cytokines in diabetes and its complications","volume":"79","author":"King","year":"2008","journal-title":"J. Periodontol."},{"key":"10.1016\/j.bbrc.2024.150558_bib20","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/s12035-023-03534-1","article-title":"Impaired removal of the damaged mitochondria in the metabolic memory phenomenon associated with continued progression of diabetic retinopathy","volume":"61","author":"Kowluru","year":"2023","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbrc.2024.150558_bib21","doi-asserted-by":"crossref","first-page":"283","DOI":"10.4161\/isl.2.5.12639","article-title":"Mitochondrial proteome analysis reveals altered expression of voltage dependent anion channels in pancreatic beta-cells exposed to high glucose","volume":"2","author":"Ahmed","year":"2010","journal-title":"Islets"},{"key":"10.1016\/j.bbrc.2024.150558_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/biom13030557","article-title":"Ablation of GPR56 causes beta-cell dysfunction by ATP loss through mistargeting of mitochondrial VDAC1 to the plasma membrane","volume":"13","author":"Mohammad Al-Amily","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.bbrc.2024.150558_bib23","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1007\/BF00403906","article-title":"The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells","volume":"39","author":"Eizirik","year":"1996","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbrc.2024.150558_bib24","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1111\/j.1463-1326.2012.01632.x","article-title":"Pancreatic beta-cell dysfunction, expression of iNOS and the effect of phosphodiesterase inhibitors in human pancreatic islets of type 2 diabetes","volume":"14","author":"Muhammed","year":"2012","journal-title":"Diabetes Obes. Metabol."},{"key":"10.1016\/j.bbrc.2024.150558_bib25","article-title":"Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1","volume":"3","author":"Salehi","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2024.150558_bib26","doi-asserted-by":"crossref","first-page":"4637","DOI":"10.1210\/jc.2016-1884","article-title":"Adhesion G protein-coupled receptor G1 (ADGRG1\/GPR56) and pancreatic beta-cell function","volume":"101","author":"Duner","year":"2016","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bbrc.2024.150558_bib27","article-title":"Functions and diseases of the retinal pigment epithelium","volume":"12","author":"Yang","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbrc.2024.150558_bib28","doi-asserted-by":"crossref","first-page":"520","DOI":"10.2337\/db22-0744","article-title":"Mitochondrial genome-encoded long noncoding RNA and mitochondrial stability in diabetic retinopathy","volume":"72","author":"Kumar","year":"2023","journal-title":"Diabetes"},{"key":"10.1016\/j.bbrc.2024.150558_bib29","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s00441-004-1013-4","article-title":"Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP\/PKA pathway","volume":"319","author":"Jimenez-Feltstrom","year":"2005","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.bbrc.2024.150558_bib30","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.202013591","article-title":"Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects","volume":"13","author":"Sadek","year":"2021","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.bbrc.2024.150558_bib31","doi-asserted-by":"crossref","first-page":"3922","DOI":"10.1016\/j.jmb.2018.07.027","article-title":"Mechanisms orchestrating mitochondrial dynamics for energy homeostasis","volume":"430","author":"Yu","year":"2018","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbrc.2024.150558_bib32","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.bbrc.2018.10.050","article-title":"Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2","volume":"505","author":"Aono","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2024.150558_bib33","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1126\/science.aav4011","article-title":"VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease","volume":"366","author":"Kim","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2024.150558_bib34","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201949799","article-title":"Mitochondrial DNA in inflammation and immunity","volume":"21","author":"Riley","year":"2020","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbrc.2024.150558_bib35","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.ymthe.2021.06.024","article-title":"The role of the mitochondrial protein VDAC1 in inflammatory bowel disease: a potential therapeutic target","volume":"30","author":"Verma","year":"2022","journal-title":"Mol. Ther."},{"key":"10.1016\/j.bbrc.2024.150558_bib36","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.immuni.2020.02.002","article-title":"mtDNA activates cGAS signaling and suppresses the YAP-mediated endothelial cell proliferation program to promote inflammatory injury","volume":"52","author":"Huang","year":"2020","journal-title":"Immunity"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24010945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24010945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T22:55:12Z","timestamp":1738277712000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X24010945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":36,"alternative-id":["S0006291X24010945"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150558","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sulindac prevents increased mitochondrial VDAC1 expression and cell surface mistargeting induced by pathological conditions in retinal cells","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150558","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"150558"}}