{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T21:43:17Z","timestamp":1788471797224,"version":"build-2803163510"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["19K16909"],"award-info":[{"award-number":["19K16909"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21K06731"],"award-info":[{"award-number":["21K06731"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K08377"],"award-info":[{"award-number":["23K08377"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008731","name":"Nakatomi Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018502","name":"Kanazawa University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018502","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.bbrc.2024.150625","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T06:21:12Z","timestamp":1724912472000},"page":"150625","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Chemogenetic inhibition of pain-related neurons in the posterior insula cortex reduces mechanical hyperalgesia and anxiety-like behavior during acute pain"],"prefix":"10.1016","volume":"734","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9743-8700","authenticated-orcid":false,"given":"Ilia Viktorovich","family":"Potapenko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6699-9940","authenticated-orcid":false,"given":"Tatsuya","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6252-9634","authenticated-orcid":false,"given":"Hiroaki","family":"Okuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyomi","family":"Hori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Ozaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2024.150625_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/wcs.1201","article-title":"Pain","volume":"4","author":"Melzack","year":"2013","journal-title":"WIREs Cogn. Sci."},{"key":"10.1016\/j.bbrc.2024.150625_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.149800","article-title":"Real-time monitoring of cortical brain activity in response to acute pain using wide-area Ca2+ imaging","volume":"708","author":"Inami","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2024.150625_bib3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1152\/physrev.00040.2019","article-title":"Cellular circuits in the brain and their modulation in acute and chronic pain","volume":"101","author":"Kuner","year":"2021","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbrc.2024.150625_bib4","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.tics.2021.01.001","article-title":"Cognition in the chronic pain experience: preclinical insights","volume":"25","author":"Phelps","year":"2021","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.bbrc.2024.150625_bib5","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/s41583-021-00468-2","article-title":"Neocortical circuits in pain and pain relief","volume":"22","author":"Tan","year":"2021","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib6","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.1523\/JNEUROSCI.14-07-04095.1994","article-title":"Distributed processing of pain and vibration by the human brain","volume":"14","author":"Coghill","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib7","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1038\/s41593-019-0469-1","article-title":"Aversive state processing in the posterior insular cortex","volume":"22","author":"Gehrlach","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib8","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1093\/brain\/aws199","article-title":"Anterior insular cortex is necessary for empathetic pain perception","volume":"135","author":"Gu","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.bbrc.2024.150625_bib9","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.2062-23.2024","article-title":"Insula\u2192Amygdala and Insula\u2192Thalamus pathways are involved in comorbid chronic pain and depression-like behavior in mice","volume":"44","author":"Chen","year":"2024","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib10","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1126\/science.abj8817","article-title":"Fear balance is maintained by bodily feedback to the insular cortex in mice","volume":"374","author":"Klein","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2024.150625_bib11","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1093\/brain\/awq220","article-title":"Operculo-insular pain (parasylvian pain): a distinct central pain syndrome","volume":"133","author":"Garcia-Larrea","year":"2010","journal-title":"Brain"},{"key":"10.1016\/j.bbrc.2024.150625_bib12","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1523\/JNEUROSCI.5173-08.2009","article-title":"Roles of the insular cortex in the modulation of pain: insights from brain lesions","volume":"29","author":"Starr","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib13","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ejpain.2010.06.007","article-title":"Insular cortex lesion diminishes neuropathic and inflammatory pain-like behaviours","volume":"15","author":"Coffeenl","year":"2011","journal-title":"Eur. J. Pain"},{"key":"10.1016\/j.bbrc.2024.150625_bib14","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1002\/hbm.20213","article-title":"Using fMRI to dissociate sensory encoding from cognitive evaluation of heat pain intensity","volume":"27","author":"Kong","year":"2006","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.bbrc.2024.150625_bib15","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.neuroimage.2012.09.038","article-title":"The \u2018where\u2019 and the \u2018when\u2019 of the BOLD response to pain in the insular cortex. Discussion on amplitudes and latencies","volume":"64","author":"Pomares","year":"2013","journal-title":"Neuroimage"},{"key":"10.1016\/j.bbrc.2024.150625_bib16","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nn.3969","article-title":"The dorsal posterior insula subserves a fundamental role in human pain","volume":"18","author":"Segerdahl","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib17","doi-asserted-by":"crossref","first-page":"5486","DOI":"10.1002\/hbm.22565","article-title":"Processing of nociceptive input from posterior to anterior insula in humans","volume":"35","author":"Frot","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.bbrc.2024.150625_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2024.120549","article-title":"fMRI, LFP, and anatomical evidence for hierarchical nociceptive routing pathway between somatosensory and insular cortices","volume":"289","author":"Zhu","year":"2024","journal-title":"Neuroimage"},{"key":"10.1016\/j.bbrc.2024.150625_bib19","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.jpain.2023.10.005","article-title":"Chemogenetic modulation of posterior insula CaMKIIa neurons alters pain and thermoregulation","volume":"25","author":"Kadakia","year":"2024","journal-title":"J. Pain"},{"key":"10.1016\/j.bbrc.2024.150625_bib20","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1038\/nn.4645","article-title":"A pathway from midcingulate cortex to posterior insula gates nociceptive hypersensitivity","volume":"20","author":"Tan","year":"2017","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib21","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1007\/s12017-023-08752-3","article-title":"Optogenetic inhibition of glutamatergic neurons in the dysgranular posterior insular cortex modulates trigeminal neuropathic pain in CCI-ION rat","volume":"25","author":"Islam","year":"2023","journal-title":"NeuroMolecular Med."},{"key":"10.1016\/j.bbrc.2024.150625_bib22","doi-asserted-by":"crossref","first-page":"5902","DOI":"10.1016\/j.cell.2021.10.013","article-title":"Insular cortex neurons encode and retrieve specific immune responses","volume":"184","author":"Koren","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2024.150625_bib23","doi-asserted-by":"crossref","first-page":"5073","DOI":"10.1038\/s41467-023-40517-1","article-title":"Linking emotional valence and anxiety in a mouse insula-amygdala circuit","volume":"14","author":"Nicolas","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2024.150625_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2019.00330","article-title":"The role of the rodent insula in anxiety","volume":"10","author":"M\u00e9ndez-Ruette","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bbrc.2024.150625_bib25","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.biopsych.2006.03.042","article-title":"An insular view of anxiety","volume":"60","author":"Paulus","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbrc.2024.150625_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2022.114006","article-title":"Evaluation of the posterior insular cortex involvement in anxiogenic response to emotional stress in male rats: functional topography along the rostrocaudal axis","volume":"258","author":"Vitorio","year":"2023","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.bbrc.2024.150625_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111833","article-title":"A nociceptive neuronal ensemble in the dorsomedial prefrontal cortex underlies pain chronicity","volume":"41","author":"Qi","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150625_bib28","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.neuron.2013.03.025","article-title":"Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populations","volume":"78","author":"Guenthner","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150625_bib29","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.cell.2016.05.010","article-title":"Wiring and molecular features of prefrontal ensembles representing distinct experiences","volume":"165","author":"Ye","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2024.150625_bib30","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.1038\/nprot.2006.450","article-title":"Stereotaxic gene delivery in the rodent brain","volume":"1","author":"Cetin","year":"2006","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbrc.2024.150625_bib31","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1538\/expanim.60.481","article-title":"Effect of three types of mixed anesthetic agents alternate to ketamine in mice","volume":"60","author":"Kawai","year":"2011","journal-title":"Exp. Anim."},{"key":"10.1016\/j.bbrc.2024.150625_bib32","first-page":"967","volume":"vol. 60","author":"Dixon","year":"1965"},{"key":"10.1016\/j.bbrc.2024.150625_bib33","author":"Lopes"},{"key":"10.1016\/j.bbrc.2024.150625_bib34","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1111\/2041-210X.12874","article-title":"ToxTrac: a fast and robust software for tracking organisms","volume":"9","author":"Rodriguez","year":"2018","journal-title":"Methods Ecol. Evol."},{"key":"10.1016\/j.bbrc.2024.150625_bib35","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-15104-2","article-title":"ToxId: an efficient algorithm to solve occlusions when tracking multiple animals","volume":"7","author":"Rodriguez","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2024.150625_bib36","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.cell.2020.04.007","article-title":"The allen mouse brain common coordinate framework: a 3D reference atlas","volume":"181","author":"Wang","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2024.150625_bib37","doi-asserted-by":"crossref","DOI":"10.1038\/nmeth.2019","article-title":"Fiji - an Open Source platform for biological image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbrc.2024.150625_bib38","doi-asserted-by":"crossref","DOI":"10.3389\/fcomp.2021.780026","article-title":"An open-source whole slide image registration workflow at cellular precision using Fiji, QuPath and elastix","volume":"3","author":"Chiaruttini","year":"2022","journal-title":"Front. Comput. Sci."},{"key":"10.1016\/j.bbrc.2024.150625_bib39","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-17204-5","article-title":"QuPath: open source software for digital pathology image analysis","volume":"7","author":"Bankhead","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2024.150625_bib40","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1111\/j.1471-4159.2011.07628.x","article-title":"Activation of transient receptor potential ankyrin 1 evokes nociception through substance P release from primary sensory neurons","volume":"120","author":"Nakamura","year":"2012","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbrc.2024.150625_bib41","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.pain.2007.06.005","article-title":"Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors","volume":"135","author":"Ruparel","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.bbrc.2024.150625_bib42","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1186\/1744-8069-8-75","article-title":"Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception","volume":"8","author":"Weng","year":"2012","journal-title":"Mol. Pain"},{"key":"10.1016\/j.bbrc.2024.150625_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2023.1185243","article-title":"Differences in the neural basis and transcriptomic patterns in acute and persistent pain-related anxiety-like behaviors","volume":"16","author":"Fang","year":"2023","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.1006125","article-title":"Acid-sensing ion channel 1a in the central nucleus of the amygdala regulates anxiety-like behaviors in a mouse model of acute pain","volume":"15","author":"Shi","year":"2023","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib45","first-page":"236","article-title":"The anterior cingulate cortex is a critical hub for pain-induced depression, biol","volume":"77","author":"Barthas","year":"2015","journal-title":"Psychiatry"},{"key":"10.1016\/j.bbrc.2024.150625_bib46","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.tins.2017.02.002","article-title":"The insula: an underestimated brain area in clinical neuroscience, psychiatry, and neurology","volume":"40","author":"Namkung","year":"2017","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib47","article-title":"The mechanisms of pain tolerance and pain-related anxiety in acute pain, Health Psychol","volume":"6","author":"Cimpean","year":"2019","journal-title":"Open"},{"key":"10.1016\/j.bbrc.2024.150625_bib48","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1080\/00325481.2019.1663705","article-title":"Depression, anxiety and acute pain: links and management challenges","volume":"131","author":"Michaelides","year":"2019","journal-title":"Postgrad. Med."},{"key":"10.1016\/j.bbrc.2024.150625_bib49","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1007\/s00213-015-4071-2","article-title":"Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex","volume":"232","author":"Luo","year":"2015","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.bbrc.2024.150625_bib50","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abn4408","article-title":"Itch-specific neurons in the ventrolateral orbital cortex selectively modulate the itch processing","volume":"8","author":"Jiang","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.bbrc.2024.150625_bib51","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1126\/science.aap8586","article-title":"An amygdalar neural ensemble that encodes the unpleasantness of pain","volume":"363","author":"Corder","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2024.150625_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.106332","article-title":"Pain-related neuronal ensembles in the primary somatosensory cortex contribute to hyperalgesia and anxiety","volume":"26","author":"Ishikawa","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.bbrc.2024.150625_bib53","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2022.878927","article-title":"Site-specific regulation of stress responses along the rostrocaudal Axis of the insular cortex in rats","volume":"16","author":"Tomeo","year":"2022","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbrc.2024.150625_bib54","doi-asserted-by":"crossref","DOI":"10.1007\/s00429-023-02654-7","article-title":"A new map of the rat isocortex and proisocortex: cytoarchitecture and M2 receptor distribution patterns","author":"Haghir","year":"2023","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.bbrc.2024.150625_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.55585","article-title":"A whole-brain connectivity map of mouse insular cortex","volume":"9","author":"Gehrlach","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.bbrc.2024.150625_bib56","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/j.neuron.2022.03.030","article-title":"Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain","volume":"110","author":"Zhang","year":"2022","journal-title":"Neuron"},{"key":"10.1016\/j.bbrc.2024.150625_bib57","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1097\/j.pain.0000000000000615","article-title":"Insular balance of glutamatergic and GABAergic signaling modulates pain processing","volume":"157","author":"Watson","year":"2016","journal-title":"Pain"},{"key":"10.1016\/j.bbrc.2024.150625_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2022.102207","article-title":"Distinct basolateral amygdala excitatory inputs mediate the somatosensory and aversive-affective components of pain","volume":"298","author":"Meng","year":"2022","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrc.2024.150625_bib59","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.celrep.2019.09.011","article-title":"Dual and opposing functions of the central amygdala in the modulation of pain","volume":"29","author":"Wilson","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2024.150625_bib60","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/j.cub.2020.02.091","article-title":"Mapping cortical integration of sensory and affective pain pathways","volume":"30","author":"Singh","year":"2020","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bbrc.2024.150625_bib61","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2114094119","article-title":"Pain hypersensitivity in a pharmacological mouse model of attention-deficit\/hyperactivity disorder","volume":"119","author":"Bouchatta","year":"2022","journal-title":"Proc. Natl. Acad. Sci."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24011616?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X24011616?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T19:32:00Z","timestamp":1732649520000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X24011616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":61,"alternative-id":["S0006291X24011616"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150625","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chemogenetic inhibition of pain-related neurons in the posterior insula cortex reduces mechanical hyperalgesia and anxiety-like behavior during acute pain","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2024.150625","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"150625"}}