{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:05:15Z","timestamp":1770681915435,"version":"3.49.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.bbrc.2025.151410","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T16:06:20Z","timestamp":1738080380000},"page":"151410","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["TFAP2B governs the regulation of SIRT1 to inhibit osteoclast-induced bone destruction"],"prefix":"10.1016","volume":"752","author":[{"given":"Liting","family":"Wen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxia","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zengping","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4597-5659","authenticated-orcid":false,"given":"Peixiong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dapeng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianhai","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2025.151410_bib1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s12105-018-0915-5","article-title":"Cholesteatoma pearls: practical points and update","volume":"12","author":"Castle","year":"2018","journal-title":"Head and neck pathology"},{"key":"10.1016\/j.bbrc.2025.151410_bib2","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1007\/s12105-018-0952-0","article-title":"Idiopathic, infectious and reactive lesions of the ear and temporal bone","volume":"12","author":"Magliocca","year":"2018","journal-title":"Head and neck pathology"},{"key":"10.1016\/j.bbrc.2025.151410_bib3","first-page":"3959","article-title":"MDCT of the temporal bone and audiological findings of pediatric acquired cholesteatoma","volume":"274","author":"Tanrivermis Sayit","year":"2017","journal-title":"Eur. Arch. Oto-Rhino-Laryngol. : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery"},{"key":"10.1016\/j.bbrc.2025.151410_bib4","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/00016489.2016.1222549","article-title":"Presence of osteoclasts in middle ear cholesteatoma: a study of undecalcified bone sections","volume":"137","author":"Koizumi","year":"2017","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.bbrc.2025.151410_bib5","first-page":"217","article-title":"Chronic otitis media and cholesteatoma, U","volume":"17","author":"Chole","year":"2009","journal-title":"Ballenger's Otorhinolaryngology Head and Neck Surgery"},{"key":"10.1016\/j.bbrc.2025.151410_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052718","article-title":"Identification of novel cholesteatoma-related gene expression signatures using full-genome microarrays","volume":"7","author":"Klenke","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2025.151410_bib7","doi-asserted-by":"crossref","unstructured":"L. Fu, K. Shi, J. Wang, W. Chen, D. Shi, Y. Tian, W. Guo, W. Yu, X. Xiao, T. Kang, S. Wang, W. Huang, W. Deng, TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF\/PEDF signaling, Mol. Cancer 13 89. 10.1186\/1476-4598-13-89.","DOI":"10.1186\/1476-4598-13-89"},{"key":"10.1016\/j.bbrc.2025.151410_bib8","doi-asserted-by":"crossref","unstructured":"S. Ugi, Y. Nishio, H. Yamamoto, K. Ikeda, M. Kobayashi, S. Tsukada, M. Kondo, K. Morino, T. Obata, T. Yoshizaki, T. Uzu, H. Naitoh, T. Tani, S. Maeda, A. Kashiwagi, H. Maegawa, Relation of the expression of transcriptional factor TFAP2B to that of adipokines in subcutaneous and omental adipose tissues, Obesity 18 1277-1282. 10.1038\/oby.2009.442.","DOI":"10.1038\/oby.2009.442"},{"key":"10.1016\/j.bbrc.2025.151410_bib9","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1126\/science.aay6782","article-title":"Transcription factor AP2 controls cnidarian germ cell induction","volume":"367","author":"DuBuc","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.bbrc.2025.151410_bib10","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1002\/ijc.33558","article-title":"Transcription factor AP-2beta in development, differentiation and tumorigenesis","volume":"149","author":"Raap","year":"2021","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbrc.2025.151410_bib11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ydbio.2023.06.015","article-title":"Ap-2\u03b2 regulates cranial osteogenic potential via the activation of Wnt\/\u03b2-catenin signaling pathway","volume":"501","author":"Hu","year":"2023","journal-title":"Dev. Biol."},{"key":"10.1016\/j.bbrc.2025.151410_bib12","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s13105-016-0492-6","article-title":"The role of sirtuins in cellular homeostasis","volume":"72","author":"Kupis","year":"2016","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.bbrc.2025.151410_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10408398.2023.2214208","article-title":"Sirtuin 1 as a potential biomarker of undernutrition in the elderly: a narrative review","author":"Kujawowicz","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.bbrc.2025.151410_bib14","article-title":"Histone acetylation in the epigenetic regulation of bone metabolism and related diseases","volume":"2021","author":"Tian","year":"2021","journal-title":"Stem Cell. Int."},{"key":"10.1016\/j.bbrc.2025.151410_bib15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.mce.2018.02.015","article-title":"SIRT1 suppresses high glucose and palmitate-induced osteoclast differentiation via deacetylating p66Shc","volume":"474","author":"Qu","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.bbrc.2025.151410_bib16","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.7150\/ijbs.48169","article-title":"SIRT1\/FOXO3a axis plays an important role in the prevention of mandibular bone loss induced by 1,25(OH)(2)D deficiency","volume":"16","author":"Chen","year":"2020","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.bbrc.2025.151410_bib17","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.bbadis.2015.07.007","article-title":"Suppression of RANKL-induced osteoclast differentiation by cilostazol via SIRT1-induced RANK inhibition","volume":"1852","author":"Park","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbrc.2025.151410_bib18","article-title":"Mechanical disturbance of osteoclasts induces ATP release that leads to protein synthesis in skeletal muscle through an akt-mTOR signaling pathway","volume":"23","author":"C","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2025.151410_bib19","doi-asserted-by":"crossref","first-page":"8380","DOI":"10.3892\/mmr.2017.7625","article-title":"High-dose PMA with RANKL and MCSF induces THP-1 cell differentiation into human functional osteoclasts in vitro","volume":"16","author":"Li","year":"2017","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.bbrc.2025.151410_bib20","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1111\/jcmm.14277","article-title":"Overview of RAW264. 7 for osteoclastogensis study: phenotype and stimuli","volume":"23","author":"Kong","year":"2019","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.bbrc.2025.151410_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23169444","article-title":"Mechanical disturbance of osteoclasts induces ATP release that leads to protein synthesis in skeletal muscle through an Akt-mTOR signaling pathway","volume":"23","author":"Morales-Jim\u00e9nez","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2025.151410_bib22","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.biopha.2018.05.030","article-title":"Particle-induced SIRT1 downregulation promotes osteoclastogenesis and osteolysis through ER stress regulation","volume":"104","author":"Zhang","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbrc.2025.151410_bib23","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/1947601913476948","article-title":"Deacetylation by SIRT1 reprograms inflammation and cancer","volume":"4","author":"Liu","year":"2013","journal-title":"Genes Cancer"},{"key":"10.1016\/j.bbrc.2025.151410_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154739","article-title":"Safranal inhibits estrogen-deficiency osteoporosis by targeting Sirt1 to interfere with NF-\u03baB acetylation","volume":"114","author":"Sheng","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bbrc.2025.151410_bib25","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.metabol.2018.01.005","article-title":"Iron-induced oxidative stress stimulates osteoclast differentiation via NF-\u03baB signaling pathway in mouse model","volume":"83","author":"X","year":"2018","journal-title":"Metab., Clin. Exp."},{"key":"10.1016\/j.bbrc.2025.151410_bib26","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1186\/s12967-023-04449-0","article-title":"CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation through NF-\u03baB signaling pathway in ankylosing spondylitis in vitro","volume":"21","author":"X","year":"2023","journal-title":"J. Transl. Med."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X2500124X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X2500124X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T20:12:46Z","timestamp":1740082366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X2500124X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":26,"alternative-id":["S0006291X2500124X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.151410","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TFAP2B governs the regulation of SIRT1 to inhibit osteoclast-induced bone destruction","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.151410","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"151410"}}