{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T07:57:54Z","timestamp":1791705474663,"version":"4.3.4"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008867","name":"Department of Education of Zhejiang Province","doi-asserted-by":"publisher","award":["Y202354004"],"award-info":[{"award-number":["Y202354004"]}],"id":[{"id":"10.13039\/501100008867","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42406087"],"award-info":[{"award-number":["42406087"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQ24D060001"],"award-info":[{"award-number":["LQ24D060001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.bbrc.2025.152155","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T23:13:29Z","timestamp":1748992409000},"page":"152155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Comparison between Western Reserve strain and Tiantan strain of oncolytic vaccinia virus vector expressing exogenous gene Aphracilistes vastus lectin"],"prefix":"10.1016","volume":"775","author":[{"given":"Huiwei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4952-8140","authenticated-orcid":false,"given":"Yanrong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gongchu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2025.152155_bib1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/s41571-022-00719-w","article-title":"Therapy with oncolytic viruses: progress and challenges","volume":"20","author":"Shalhout","year":"2023","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.bbrc.2025.152155_bib2","article-title":"Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response","volume":"13","author":"Wu","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bbrc.2025.152155_bib3","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/s13104-020-05068-4","article-title":"Effect of oncolytic ECHO-7 virus strain Rigvir on uveal melanoma cell lines","volume":"13","author":"Tilgase","year":"2020","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.bbrc.2025.152155_bib4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.2174\/1568009618666171129221503","article-title":"Oncorine, the world first oncolytic virus medicine and its update in China","volume":"18","author":"Liang","year":"2018","journal-title":"Curr. Cancer Drug Targets"},{"key":"10.1016\/j.bbrc.2025.152155_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40257-016-0238-9","article-title":"Talimogene laherparepvec (T-VEC) and other oncolytic viruses for the treatment of melanoma","volume":"18","author":"Bommareddy","year":"2017","journal-title":"Am. J. Clin. Dermatol."},{"key":"10.1016\/j.bbrc.2025.152155_bib6","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s40259-022-00553-7","article-title":"Teserpaturev\/G47\u0394: first approval","volume":"36","author":"Frampton","year":"2022","journal-title":"BioDrugs"},{"key":"10.1016\/j.bbrc.2025.152155_bib7","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.3390\/v14102206","article-title":"The Vaccinia virus DNA helicase structure from combined single-particle cryo-electron microscopy and AlphaFold2 prediction","volume":"14","author":"Hutin","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.bbrc.2025.152155_bib8","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.3390\/biomedicines9121780","article-title":"Vaccinia virus: from crude smallpox vaccines to elaborate viral Vector vaccine design","volume":"9","author":"Kaynarcalidan","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.bbrc.2025.152155_bib9","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1091\/mbc.12.7.2031","article-title":"Vaccinia virus DNA replication occurs in endoplasmic reticulum-enclosed cytoplasmic mini-nuclei","volume":"12","author":"Tolonen","year":"2001","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbrc.2025.152155_bib10","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s12250-020-00250-1","article-title":"Freeze-drying formulations increased the adenovirus and poxvirus vaccine storage times and antigen stabilities","volume":"36","author":"Chen","year":"2021","journal-title":"Virol. Sin."},{"key":"10.1016\/j.bbrc.2025.152155_bib11","doi-asserted-by":"crossref","first-page":"4388","DOI":"10.1158\/1078-0432.CCR-18-0244","article-title":"Phase I study of oncolytic vaccinia virus GL-ONC1 in patients with peritoneal carcinomatosis","volume":"24","author":"Lauer","year":"2018","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.bbrc.2025.152155_bib12","doi-asserted-by":"crossref","DOI":"10.1093\/neuonc\/noab180.122","article-title":"P13.15 Pre-clinical trial of T601 oncolytic virus for high grade glima via intra-tumoral injection","author":"He","year":"2021","journal-title":"Neuro Oncol."},{"key":"10.1016\/j.bbrc.2025.152155_bib13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/glycob\/11.1.21","article-title":"Isolation and cloning of a C-type lectin from the hexactinellid sponge aphrocallistes vastus: a putative aggregation factor","volume":"11","author":"Gundacker","year":"2001","journal-title":"Glycobiology (Oxf.)"},{"key":"10.1016\/j.bbrc.2025.152155_bib14","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/mt.2014.194","article-title":"First-in-man study of western reserve strain oncolytic vaccinia virus: safety, systemic spread, and antitumor activity","volume":"23","author":"Zeh","year":"2015","journal-title":"Mol. Ther."},{"key":"10.1016\/j.bbrc.2025.152155_bib15","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3390\/md17060363","article-title":"Oncolytic Vaccinia virus expressing Aphrocallistes vastus lectin as a cancer therapeutic agent","volume":"17","author":"Wu","year":"2019","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.bbrc.2025.152155_bib16","doi-asserted-by":"crossref","first-page":"378","DOI":"10.3390\/md20060378","article-title":"Oncolytic vaccinia virus harboring Aphrocallistes vastus lectin inhibits the growth of hepatocellular carcinoma cells","volume":"20","author":"Jiang","year":"2022","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.bbrc.2025.152155_bib17","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3390\/md22070307","article-title":"ROS induced by Aphrocallistes vastus lectin enhance oncolytic vaccinia Virus replication and induce apoptosis in hepatocellular carcinoma cells","volume":"22","author":"Zhang","year":"2024","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.bbrc.2025.152155_bib18","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.3390\/ijms24043823","article-title":"Effects of oncolytic Vaccinia viruses harboring different marine lectins on hepatocellular carcinoma cells","volume":"24","author":"Zhou","year":"2023","journal-title":"IJMS"},{"key":"10.1016\/j.bbrc.2025.152155_bib19","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3390\/md20110667","article-title":"Oncolytic vaccinia virus carrying Aphrocallistes vastus lectin (oncoVV-AVL) enhances inflammatory response in hepatocellular carcinoma cells","volume":"20","author":"Zheng","year":"2022","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.bbrc.2025.152155_bib20","unstructured":"J. Yu, AVL-armed oncolytic vaccinia virus promotes viral replication and boosts antitumor immunity via increasing ROS levels in pancreatic cancer, Mol. Ther. (n.d.)."},{"key":"10.1016\/j.bbrc.2025.152155_bib21","article-title":"CD109 promotes drug resistance in A2780 ovarian cancer cells by regulating the STAT3-NOTCH1 signaling axis","volume":"24","author":"Kim","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2025.152155_bib22","first-page":"109","article-title":"Effects of growth factor deprivation on MKN-45 spheroid cells","volume":"47","author":"T\u00fcrksoy Terzio\u011flu","year":"2023","journal-title":"Turk. J. Biol. = Turk Biyol. Derg."},{"key":"10.1016\/j.bbrc.2025.152155_bib23","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.3390\/ijms25063498","article-title":"PANC-1 cell line as an experimental model for characterizing PIVKA-II production, distribution, and molecular mechanisms leading to protein release in PDAC","volume":"25","author":"Farina","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2025.152155_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.150355","article-title":"Oncolytic vaccinia virus harboring aphrocallistes vastus lectin exerts anti-tumor effects by directly oncolysis and inducing immune response through enhancing ROS in human ovarian cancer","volume":"730","author":"Zhang","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2025.152155_bib25","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1089\/hum.2024.100","article-title":"Oncolytic vaccinia virus encoding aphrocallistes vastus lectin suppresses the proliferation of gastric cancer cells","volume":"35","author":"Zhu","year":"2024","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.bbrc.2025.152155_bib26","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2024.2306967","article-title":"Vaccinia virus tiantan strain is inefficient in eliciting cross-reactive immunity against the emerging monkeypox virus strain","volume":"13","author":"Tian","year":"2024","journal-title":"Emerg Microbes Infect"},{"key":"10.1016\/j.bbrc.2025.152155_bib27","article-title":"Oncolytic vaccinia virus harboring CLEC2A gene enhances viral replication and antitumor efficacy","volume":"32","author":"Gao","year":"2024","journal-title":"Mol. Ther. Oncol."},{"key":"10.1016\/j.bbrc.2025.152155_bib28","doi-asserted-by":"crossref","first-page":"7073","DOI":"10.3390\/ijms21197073","article-title":"Efficient delivery and replication of oncolytic virus for successful treatment of head and neck cancer","volume":"21","author":"Hamada","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2025.152155_bib29","first-page":"47","article-title":"The vaccinia virus A27L protein is needed for the microtubule-dependent transport of intracellular mature virus particles","volume":"81","author":"Sanderson","year":"2000","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.bbrc.2025.152155_bib30","doi-asserted-by":"crossref","first-page":"4146","DOI":"10.1158\/0008-5472.CAN-16-2165","article-title":"Immune checkpoint blockade, immunogenic chemotherapy or IFN-\u03b1 blockade boost the local and abscopal effects of oncolytic virotherapy","volume":"77","author":"Fend","year":"2017","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbrc.2025.152155_bib31","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/j.bcp.2006.06.002","article-title":"Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages","volume":"72","author":"Solis","year":"2006","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbrc.2025.152155_bib32","doi-asserted-by":"crossref","first-page":"462","DOI":"10.3389\/fcimb.2017.00462","article-title":"Generation of an attenuated Tiantan Vaccinia Virus strain by deletion of multiple genes","volume":"7","author":"Li","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bbrc.2025.152155_bib33","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.02651-23","article-title":"The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication","volume":"14","author":"Zhang","year":"2023","journal-title":"mBio"},{"key":"10.1016\/j.bbrc.2025.152155_bib34","first-page":"219","article-title":"Oxidative stress influences positive strand RNA virus genome synthesis and capping","volume":"475","author":"Gullberg","year":"2015","journal-title":"Virology (New York, N. Y.)"},{"key":"10.1016\/j.bbrc.2025.152155_bib35","article-title":"Anlotinib benefits the \u03b1PDL1 immunotherapy by activating ROS\/JNK\/AP-1 pathway to upregulate PDL1 expression in colorectal cancer, oxid. Med","volume":"2022","author":"Luo","year":"2022","journal-title":"Cell. Longevity"},{"key":"10.1016\/j.bbrc.2025.152155_bib36","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2020-001372","article-title":"Mitochondrial lon-induced mtDNA leakage contributes to PD-L1\u2013mediated immunoescape via STING-IFN signaling and extracellular vesicles","volume":"8","author":"Cheng","year":"2020","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.bbrc.2025.152155_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153216","article-title":"Effect of epiberberine from coptis chinensis franch on inhibition of tumor growth in MKN-45 xenograft mice","volume":"76","author":"Yu","year":"2020","journal-title":"Phytomed.: Int. J. Phytother. Phytopharm."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X25008691?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X25008691?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T08:00:16Z","timestamp":1751961616000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X25008691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":37,"alternative-id":["S0006291X25008691"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.152155","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison between Western Reserve strain and Tiantan strain of oncolytic vaccinia virus vector expressing exogenous gene Aphracilistes vastus lectin","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.152155","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"152155"}}