{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T04:45:12Z","timestamp":1792989912685,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018531","name":"Major Science and Technology Projects in Yunnan Province","doi-asserted-by":"publisher","award":["202403AP140030"],"award-info":[{"award-number":["202403AP140030"]}],"id":[{"id":"10.13039\/501100018531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007839","name":"Yunnan University","doi-asserted-by":"publisher","award":["YDYXJJ2024-0011"],"award-info":[{"award-number":["YDYXJJ2024-0011"]}],"id":[{"id":"10.13039\/501100007839","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007839","name":"Yunnan University","doi-asserted-by":"publisher","award":["XDYC-MY-2022-0025"],"award-info":[{"award-number":["XDYC-MY-2022-0025"]}],"id":[{"id":"10.13039\/501100007839","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007839","name":"Yunnan University","doi-asserted-by":"publisher","award":["YDYXJJ2024-0018"],"award-info":[{"award-number":["YDYXJJ2024-0018"]}],"id":[{"id":"10.13039\/501100007839","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.bbrc.2025.152174","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T02:05:02Z","timestamp":1749434702000},"page":"152174","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Echinatin ameliorates hyperglycemia and associated pathogenesis, oxidative stress and inflammation in STZ-induced diabetes in rats"],"prefix":"10.1016","volume":"777","author":[{"given":"Xiaogang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanfu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saman","family":"Jalili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2025.152174_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.diabres.2019.107843","article-title":"Global and regional diabetes prevalence esti\u2010 mates for 2019 and projections for 2030 and 2045: results from the international diabetes Federation diabetes atlas, 9(th) edition","volume":"157","author":"Saeedi","year":"2019","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"1","key":"10.1016\/j.bbrc.2025.152174_bib2","doi-asserted-by":"crossref","DOI":"10.2174\/1573399819666230413094200","article-title":"Prevalence of Diabetes in India: A Review of IDF Diabetes Atlas","volume":"20","author":"Kumar","year":"2024","journal-title":"Curr Diabetes Rev"},{"issue":"84","key":"10.1016\/j.bbrc.2025.152174_bib3","first-page":"1472","article-title":"Antidiabetic activity of holothuriathomasisaponin","author":"Amira","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbrc.2025.152174_bib4","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.biopha.2017.08.032","article-title":"Antidiabetic activity of hydro-alcoholic stem bark extract of CallicarpaarboreaRoxb. with antioxidant potential in diabetic rats","volume":"95","author":"Junejo","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"7","key":"10.1016\/j.bbrc.2025.152174_bib5","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1185\/03007995.2016.1168291","article-title":"Prevalence and co-prevalence of comorbidities among patients with type 2 diabetes mellitus","volume":"32","author":"Iglay","year":"2016","journal-title":"Curr. Med. Res. Opin."},{"issue":"1","key":"10.1016\/j.bbrc.2025.152174_bib6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jcjd.2015.09.002","article-title":"Comorbidity burden and health services use in community-living older adults with diabetes mellitus: a retrospective cohort study","volume":"40","author":"Gruneir","year":"2016","journal-title":"Can. J. Diabetes"},{"issue":"1","key":"10.1016\/j.bbrc.2025.152174_bib7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/1753-0407.12818","article-title":"Association between different types of comorbidity and disease burden in patients with diabetes","volume":"11","author":"An","year":"2019","journal-title":"J. Diabetes"},{"issue":"9","key":"10.1016\/j.bbrc.2025.152174_bib8","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/nrendo.2013.102","article-title":"Diabetes and its comorbidities--where East meets West","volume":"9","author":"Kong","year":"2013","journal-title":"Nat. Rev. Endocrinol."},{"issue":"9","key":"10.1016\/j.bbrc.2025.152174_bib9","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2023-076261","article-title":"Prevalence of comorbidities and its associated factors among type-2 diabetes patients: a hospital-based study in Jashore District, Bangladesh","volume":"13","author":"Shuvo","year":"2023","journal-title":"BMJ Open"},{"key":"10.1016\/j.bbrc.2025.152174_bib10","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1186\/s12889-016-3335-z","article-title":"Patterns of multimorbidity and their association with health outcomes within Yorkshire, England: baseline results from the Yorkshire Health study","volume":"16","author":"Li","year":"2016","journal-title":"BMC Public Health"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152174_bib11","doi-asserted-by":"crossref","first-page":"598","DOI":"10.4239\/wjd.v6.i4.598","article-title":"Type 2 diabetes mellitus: from a metabolic disorder to an inflammatory condition","volume":"6","author":"Hameed","year":"2015","journal-title":"World J. Diabetes"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152174_bib12","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.13852","article-title":"Analysis of polyphenols in Aegle marmelos leaf and ameliorative efficacy against diabetic mice through restoration of antioxidant and anti-inflammatory status","volume":"46","author":"Ibrahim","year":"2022","journal-title":"J. Food Biochem."},{"issue":"3","key":"10.1016\/j.bbrc.2025.152174_bib13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.ejim.2010.12.003","article-title":"The effects of atorvastatin and rosuvastatin on oxidative stress in diabetic patients","volume":"22","author":"Koksal","year":"2011","journal-title":"Eur. J. Intern. Med."},{"key":"10.1016\/j.bbrc.2025.152174_bib14","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.freeradbiomed.2022.03.019","article-title":"Oxidative stress in the pathophysiology of type 2 diabetes and related complications: current therapeutics strategies and future perspectives","volume":"184","author":"Bhatti","year":"2022","journal-title":"Free Radic. Biol. Med."},{"issue":"9","key":"10.1016\/j.bbrc.2025.152174_bib15","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1161\/CIRCRESAHA.110.223545","article-title":"Oxidative stress and diabetic complications","volume":"107","author":"Giacco","year":"2010","journal-title":"Circ. Res."},{"issue":"5","key":"10.1016\/j.bbrc.2025.152174_bib16","doi-asserted-by":"crossref","first-page":"418","DOI":"10.4103\/1735-5362.297844","article-title":"Melatonin suppresses the brain injury after cerebral ischemia\/reperfusion in hyperglycaemic rats","volume":"15","author":"Saleh","year":"2020","journal-title":"Res. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.bbrc.2025.152174_bib17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.immuni.2021.12.013","article-title":"Inflammation in obesity, diabetes, and related disorders","volume":"55","author":"Rohm","year":"2022","journal-title":"Immunity (Camb., Mass.)"},{"issue":"12","key":"10.1016\/j.bbrc.2025.152174_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0051768","article-title":"Adipocytokines, hepatic and inflammatory biomarkers and incidence of type 2 diabetes. theCoLaus study","volume":"7","author":"Marques-Vidal","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bbrc.2025.152174_bib19","doi-asserted-by":"crossref","first-page":"50","DOI":"10.15420\/ecr.2018.33.1","article-title":"The role of inflammation in diabetes: current concepts and future perspectives","volume":"14","author":"Tsalamandris","year":"2019","journal-title":"Eur. Cardiol."},{"key":"10.1016\/j.bbrc.2025.152174_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110708","article-title":"Type II diabetes mellitus: a review on recent drug based therapeutics","volume":"131","author":"Padhi","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"6","key":"10.1016\/j.bbrc.2025.152174_bib21","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1189\/jlb.3A0114-005RR","article-title":"Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation","volume":"96","author":"Honda","year":"2014","journal-title":"J. Leukoc. Biol."},{"issue":"2","key":"10.1016\/j.bbrc.2025.152174_bib22","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.foodchem.2013.03.089","article-title":"Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice","volume":"141","author":"Fu","year":"2013","journal-title":"Food Chem."},{"key":"10.1016\/j.bbrc.2025.152174_bib23","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s12872-016-0294-3","article-title":"Cardioprotection provided by Echinatin against ischemia\/reperfusion in isolated rat hearts","volume":"16","author":"Tian","year":"2016","journal-title":"BMC Cardiovasc. Disord."},{"issue":"2","key":"10.1016\/j.bbrc.2025.152174_bib24","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.134601","article-title":"Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90","volume":"6","author":"Xu","year":"2021","journal-title":"JCI Insight"},{"key":"10.1016\/j.bbrc.2025.152174_bib25","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ejps.2016.12.005","article-title":"Phospholipid complex enriched micelles: a novel drug delivery approach for promoting the antidiabetic effect of repaglinide","volume":"99","author":"Kassem","year":"2017","journal-title":"Eur. J. Pharmaceut. Sci."},{"issue":"3","key":"10.1016\/j.bbrc.2025.152174_bib28","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0009-8981(79)90211-0","article-title":"A simplified assay method of superoxide dismutase activity for clinical use","volume":"92","author":"Minami","year":"1979","journal-title":"Clin. Chim. Acta"},{"issue":"6","key":"10.1016\/j.bbrc.2025.152174_bib29","first-page":"73","article-title":"Determination of catalase activity and catalase inhibition by ultraviolet spectrophtometry","author":"Xu","year":"1997","journal-title":"Environ. Chem."},{"key":"10.1016\/j.bbrc.2025.152174_bib30","first-page":"882","article-title":"Improved method for the determination of blood glutathione","volume":"61","author":"Beutler","year":"1963","journal-title":"J. Lab. Clin. Med."},{"issue":"4073","key":"10.1016\/j.bbrc.2025.152174_bib31","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1126\/science.179.4073.588","article-title":"Selenium: biochemical role as a component of glutathione peroxidase","volume":"179","author":"Rotruck","year":"1973","journal-title":"Science"},{"issue":"17","key":"10.1016\/j.bbrc.2025.152174_bib32","doi-asserted-by":"crossref","first-page":"6275","DOI":"10.3390\/ijms21176275","article-title":"Pathophysiology of Type 2 diabetes mellitus","volume":"21","author":"Galicia-Garcia","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2025.152174_bib33","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.diabres.2019.02.008","article-title":"Diabetes and Ramadan: a multicenter study in Algerian population","volume":"150","author":"Malek","year":"2019","journal-title":"Diabetes Res. Clin. Pract."},{"key":"10.1016\/j.bbrc.2025.152174_bib34","series-title":"Statpearls [Internet]. Treasure Island (FL): Statpearls Publishing","article-title":"Type 2 diabetes. [Updated 2023 Jun 23]","author":"Goyal","year":"2023"},{"key":"10.1016\/j.bbrc.2025.152174_bib35","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1016\/S0140-6736(10)60484-9","article-title":"Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies","volume":"375","author":"Sarwar","year":"2010","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.bbrc.2025.152174_bib36","doi-asserted-by":"crossref","first-page":"668","DOI":"10.2337\/dc15-2439","article-title":"Cardiovascular risk factor targets and cardiovascular disease event risk in diabetes: a pooling Project of the atherosclerosis risk in communities study, multi-ethnic study of atherosclerosis, and Jackson heart study","volume":"39","author":"Wong","year":"2016","journal-title":"Diabetes Care"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152174_bib37","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1097\/00007890-200202270-00004","article-title":"Treatment of Streptozotocin-induced diabetes mellitus by transplantation of islet cells plus bone marrow cells via portal vein in rats","volume":"73","author":"Ikebukuro","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.bbrc.2025.152174_bib38","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1016\/S0041-1345(97)00313-8","article-title":"An attempt to reverse diabetes by delayed islet cell transplantation in Humans","volume":"29","author":"Rastellini","year":"1997","journal-title":"Transplant. Proc."},{"issue":"5.47.1\u20135.47.20","key":"10.1016\/j.bbrc.2025.152174_bib39","article-title":"Streptozotocin-induced diabetic models in mice and rats","volume":"70","author":"Furman","year":"2015","journal-title":"Curr. Protoc. Pharmacol."},{"issue":"4","key":"10.1016\/j.bbrc.2025.152174_bib40","article-title":"Streptozotocin-induced diabetic models in mice and rats","volume":"1","author":"Furman","year":"2021","journal-title":"CurrProtoc"},{"key":"10.1016\/j.bbrc.2025.152174_bib41","doi-asserted-by":"crossref","first-page":"95","DOI":"10.4137\/BMI.S38440","article-title":"Significance of HbA1c test in diagnosis and prognosis of diabetic patients","volume":"11","author":"Sherwani","year":"2016","journal-title":"Biomark. Insights"},{"key":"10.1016\/j.bbrc.2025.152174_bib42","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.2337\/db11-0971","article-title":"Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study","volume":"61","author":"Beyan","year":"2012","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.bbrc.2025.152174_bib43","first-page":"453","article-title":"Advanced glycation end products (AGE) and diabetes: cause, effect, or both?","volume":"14","author":"Vlassara","year":"2014","journal-title":"CurrDiab Rep"},{"key":"10.1016\/j.bbrc.2025.152174_bib44","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1210\/en.2008-1342","article-title":"Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis","volume":"150","author":"Zhao","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbrc.2025.152174_bib45","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1146\/annurev.nutr.19.1.379","article-title":"Regulation of glucose production by the liver","volume":"19","author":"Nordlie","year":"1999","journal-title":"Annu. Rev. Nutr."},{"issue":"4","key":"10.1016\/j.bbrc.2025.152174_bib46","first-page":"257","article-title":"Effect of tetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes in streptozotocin induced diabetic rats","volume":"16","author":"Pari","year":"2005","journal-title":"J Basic ClinPhysiolPharmacol"},{"issue":"3","key":"10.1016\/j.bbrc.2025.152174_bib47","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20190124","article-title":"Fructose 1,6-bisphosphatase: getting the message across","volume":"39","author":"Timson","year":"2019","journal-title":"Biosci. Rep."},{"issue":"8","key":"10.1016\/j.bbrc.2025.152174_bib48","first-page":"1202","article-title":"Up-Date on diabetic nephropathy","volume":"12","author":"Pelle","year":"2022","journal-title":"Life (Basel)"},{"key":"10.1016\/j.bbrc.2025.152174_bib49","series-title":"Methods in Molecular Biology","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-9841-8_1","article-title":"Diabetic nephropathy: an overview","author":"Sagoo","year":"2020"},{"key":"10.1016\/j.bbrc.2025.152174_bib50","first-page":"3","article-title":"An updated overview of diabetic nephropathy: diagnosis, prognosis, treatment goals and latest guidelines","volume":"22","author":"Selby","year":"2020","journal-title":"Diabetes ObesMetab"},{"issue":"6","key":"10.1016\/j.bbrc.2025.152174_bib51","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.arcmed.2020.05.018","article-title":"Relation of copeptin with diabetic and renal function markers among patients with diabetes mellitus progressing towards diabetic nephropathy","volume":"51","author":"Noor","year":"2020","journal-title":"Arch. Med. Res."},{"issue":"1","key":"10.1016\/j.bbrc.2025.152174_bib52","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1080\/0886022X.2022.2072743","article-title":"Role of abnormal energy metabolism in the progression of chronic kidney disease and drug intervention","volume":"44","author":"Liu","year":"2022","journal-title":"Ren. Fail."},{"issue":"3","key":"10.1016\/j.bbrc.2025.152174_bib53","first-page":"411","article-title":"Impact of diabetes on renal function parameters","volume":"4","author":"Kamal","year":"2014","journal-title":"Ind J Fund Appl Life Sci."},{"issue":"3","key":"10.1016\/j.bbrc.2025.152174_bib54","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/jdi.12953","article-title":"Discordance in risk factors for the progression of diabetic retinopathy and diabetic nephropathy in patients with type 2 diabetes mellitus","volume":"10","author":"Song","year":"2019","journal-title":"J Diabetes Investig"},{"issue":"9","key":"10.1016\/j.bbrc.2025.152174_bib55","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1111\/jdi.14042","article-title":"Updates on dyslipidemia in patients with diabetes","volume":"14","author":"Ide","year":"2023","journal-title":"J Diabetes Investig"},{"key":"10.1016\/j.bbrc.2025.152174_bib56","article-title":"Circulating oxidative stress biomarkers in clinical studies on type 2 diabetes and its complications","volume":"12","author":"Bigagli","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.bbrc.2025.152174_bib57","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8609213","article-title":"Molecular mechanisms linking oxidative stress and diabetes mellitus","volume":"2020","author":"Yaribeygi","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"6","key":"10.1016\/j.bbrc.2025.152174_bib58","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9061995","article-title":"Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets","volume":"9","author":"Scioli","year":"2020","journal-title":"J. Clin. Med."},{"issue":"3","key":"10.1016\/j.bbrc.2025.152174_bib59","first-page":"45","article-title":"Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links","volume":"11","author":"Oguntibeju","year":"2019","journal-title":"Int J PhysiolPathophysiolPharmacol"},{"issue":"11","key":"10.1016\/j.bbrc.2025.152174_bib60","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1038\/nri3071","article-title":"Macrophage-mediated inflammation in metabolic disease","volume":"11","author":"Chawla","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbrc.2025.152174_bib61","article-title":"The variation and correlation of serum adiponectin, Nesfatin-1, IL-6, and TNF-\u03b1 levels in prediabetes","volume":"13","author":"Huang","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.bbrc.2025.152174_bib62","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1467-789X.2006.00270.x","article-title":"The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review","volume":"8","author":"Klok","year":"2007","journal-title":"Obes. Rev."},{"key":"10.1016\/j.bbrc.2025.152174_bib63","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1530\/eje.0.1470173","article-title":"Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women","volume":"147","author":"Matsubara","year":"2002","journal-title":"Eur. J. Endocrinol."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X25008897?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X25008897?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T08:41:44Z","timestamp":1774860104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X25008897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":61,"alternative-id":["S0006291X25008897"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.152174","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Echinatin ameliorates hyperglycemia and associated pathogenesis, oxidative stress and inflammation in STZ-induced diabetes in rats","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.152174","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"152174"}}