{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:20:39Z","timestamp":1790742039066,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100006095","name":"California Department of Pesticide Regulation","doi-asserted-by":"publisher","award":["1\/3(7)\/2020\/TMC\/ R&amp;D-II\/8823"],"award-info":[{"award-number":["1\/3(7)\/2020\/TMC\/ R&amp;D-II\/8823"]}],"id":[{"id":"10.13039\/100006095","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006095","name":"California Department of Pesticide Regulation","doi-asserted-by":"publisher","award":["1\/3(6)\/2020\/TMC\/R&amp;D-II\/3805"],"award-info":[{"award-number":["1\/3(6)\/2020\/TMC\/R&amp;D-II\/3805"]}],"id":[{"id":"10.13039\/100006095","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010476","name":"Tata Memorial Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010476","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007179","name":"Advanced Centre for Treatment, Research and Education in Cancer","doi-asserted-by":"publisher","award":["4598"],"award-info":[{"award-number":["4598"]}],"id":[{"id":"10.13039\/501100007179","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.bbrc.2025.152891","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T01:31:10Z","timestamp":1761787870000},"page":"152891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Raman spectroscopy for detecting gastric and liver cancer cells that entered a tolerant persistence state to survive cisplatin chemotherapy"],"prefix":"10.1016","volume":"790","author":[{"given":"Anjali","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0113-0293","authenticated-orcid":false,"given":"Ishika","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panchali","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arti","family":"Hole","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1664-0259","authenticated-orcid":false,"given":"Flevia","family":"Anthony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhiram","family":"Natu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duane T.","family":"Smoot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Ashktorab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murali Krishna","family":"Chilakapati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1209-189X","authenticated-orcid":false,"given":"Sanjay","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1053\/j.gastro.2020.02.068","article-title":"Global burden of 5 major types of gastrointestinal cancer","volume":"159","author":"Arnold","year":"2020","journal-title":"Gastroenterology"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152891_bib2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.livres.2023.11.004","article-title":"Hepatocellular carcinoma recurrence: predictors and management","volume":"7","author":"Abdelhamed","year":"2023","journal-title":"Liver Res"},{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib3","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-023-11143-3","article-title":"Evaluation of dynamic recurrence risk for locally advanced gastric cancer in the clinical setting of adjuvant chemotherapy: a real-world study with IPTW-based conditional recurrence analysis","volume":"23","author":"Wu","year":"2023","journal-title":"BMC Cancer"},{"issue":"6","key":"10.1016\/j.bbrc.2025.152891_bib4","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.adro.2020.07.007","article-title":"Prediction of survival and recurrence patterns by machine learning in gastric cancer cases undergoing radiation therapy and chemotherapy","volume":"5","author":"Akcay","year":"2020","journal-title":"Adv Radiat Oncol"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152891_bib5","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nrd1691","article-title":"Cellular processing of platinum anticancer drugs","volume":"4","author":"Wang","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"issue":"12","key":"10.1016\/j.bbrc.2025.152891_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241210230","article-title":"Circulating Tumor DNA as a minimal residual disease assessment and recurrence risk in patients undergoing curative-intent resection with or without adjuvant chemotherapy in colorectal cancer: a systematic review and meta-analysis","volume":"24","author":"Chidharla","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.bbrc.2025.152891_bib7","doi-asserted-by":"crossref","DOI":"10.1002\/mco2.70193","article-title":"Minimal residual disease detection: implications for clinical diagnosis and cancer patient treatment","volume":"6","author":"Song","year":"2020","journal-title":"MedComm"},{"issue":"7873","key":"10.1016\/j.bbrc.2025.152891_bib8","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1038\/s41586-021-03796-6","article-title":"Cycling cancer persister cells arise from lineages with distinct programs","volume":"596","author":"Oren","year":"2021","journal-title":"Nature"},{"issue":"18","key":"10.1016\/j.bbrc.2025.152891_bib9","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1016\/j.cell.2022.07.025","article-title":"Sublethal cytochrome c release generates drug-tolerant persister cells","volume":"185","author":"Kalkavan","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2025.152891_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104483","article-title":"Redox signaling in drug-tolerant persister cells as an emerging therapeutic target","volume":"89","author":"Zhang","year":"2023","journal-title":"EBioMedicine"},{"issue":"11","key":"10.1016\/j.bbrc.2025.152891_bib11","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1038\/s41416-021-01566-9","article-title":"Targeted therapy for drug-tolerant persister cells after imatinib treatment for gastrointestinal stromal tumours","volume":"125","author":"Ishida","year":"2021","journal-title":"Br. J. Cancer"},{"issue":"13","key":"10.1016\/j.bbrc.2025.152891_bib12","doi-asserted-by":"crossref","first-page":"3579","DOI":"10.1158\/0008-5472.CAN-13-3456","article-title":"The cancer stem cell marker aldehyde dehydrogenase is required to maintain a drug-tolerant tumor cell subpopulation","volume":"74","author":"Raha","year":"2014","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib13","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/s12943-025-02323-9","article-title":"Drug-induced tolerant persisters in tumor: mechanism, vulnerability, and perspective implication for clinical treatment","volume":"24","author":"Liu","year":"2025","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.cell.2010.02.027","article-title":"A chromatin-mediated reversible drug-tolerant State in cancer cell subpopulations","volume":"141","author":"Sharma","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.bbrc.2025.152891_bib15","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms10690","article-title":"Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells","volume":"7","author":"Ramirez","year":"2016","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.bbrc.2025.152891_bib16","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.3390\/cancers13051118","article-title":"Fighting drug resistance through the targeting of drug-tolerant persister cells","volume":"13","author":"De Conti","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152891_bib17","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1158\/2159-8290.CD-20-1265","article-title":"Ontogeny and vulnerabilities of drug-tolerant persisters in HER2+ breast cancer","volume":"12","author":"Chang","year":"2022","journal-title":"Cancer Discov."},{"issue":"7679","key":"10.1016\/j.bbrc.2025.152891_bib18","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nature24297","article-title":"Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition","volume":"551","author":"Hangauer","year":"2017","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.bbrc.2025.152891_bib19","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/s41571-023-00815-5","article-title":"Drug-tolerant persister cells in cancer: the cutting edges and future directions","volume":"20","author":"Pu","year":"2023","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"4","key":"10.1016\/j.bbrc.2025.152891_bib20","doi-asserted-by":"crossref","DOI":"10.1007\/s10555-018-9770-9","article-title":"Applications of Raman spectroscopy in cancer diagnosis","volume":"37","author":"Auner","year":"2018","journal-title":"Cancer Metastasis Rev."},{"issue":"11","key":"10.1016\/j.bbrc.2025.152891_bib21","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.31557\/APJCP.2024.25.11.3977","article-title":"Scientific advances in cancer detection using raman spectroscopy","volume":"25","author":"Jain","year":"2024","journal-title":"Asian Pac. J. Cancer Prev. APJCP"},{"issue":"2","key":"10.1016\/j.bbrc.2025.152891_bib22","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3233\/BSI-150107","article-title":"Raman spectroscopy of serum: a study on oral cancers","volume":"4","author":"Sahu","year":"2015","journal-title":"Biomed. Spectrosc. Imag."},{"issue":"9","key":"10.1016\/j.bbrc.2025.152891_bib23","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1007\/s10103-020-03218-5","article-title":"Raman spectroscopic study of cervical precancerous lesions and cervical cancer","volume":"36","author":"Wang","year":"2021","journal-title":"Laser Med. Sci."},{"issue":"5","key":"10.1016\/j.bbrc.2025.152891_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0097777","article-title":"Raman spectroscopic study of radioresistant oral cancer sublines established by fractionated ionizing radiation","volume":"9","author":"Yasser","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.bbrc.2025.152891_bib25","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1177\/0003702815620127","article-title":"Application of Raman Spectroscopy and infrared Spectroscopy in the identification of breast cancer","volume":"70","author":"Depciuch","year":"2016","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.bbrc.2025.152891_bib26","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/561242","article-title":"Current advances in the application of raman spectroscopy for molecular diagnosis of cervical cancer","volume":"2015","author":"Ramos","year":"2015","journal-title":"BioMed Res. Int."},{"issue":"14","key":"10.1016\/j.bbrc.2025.152891_bib27","doi-asserted-by":"crossref","first-page":"13565","DOI":"10.1364\/OE.19.013565","article-title":"Colorectal cancer detection by gold nanoparticle-based surface-enhanced Raman spectroscopy of blood serum and statistical analysis","volume":"19","author":"Lin","year":"2011","journal-title":"Opt. Express"},{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib28","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1039\/C2AY25544H","article-title":"Diagnostic segregation of human brain tumours using Fourier-transform infrared and\/or Raman spectroscopy coupled with discriminant analysis","volume":"5","author":"Gajjar","year":"2013","journal-title":"Anal. Methods"},{"issue":"3","key":"10.1016\/j.bbrc.2025.152891_bib29","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.pdpdt.2013.01.008","article-title":"Advances in the clinical application of Raman spectroscopy for cancer diagnostics","volume":"10","author":"Kallaway","year":"2013","journal-title":"Photodiagnosis Photodyn. Ther."},{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib30","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13148-019-0800-4","article-title":"Elevated HDAC activity and altered histone phospho-acetylation confer acquired radio-resistant phenotype to breast cancer cells","volume":"12","author":"Sharda","year":"2020","journal-title":"Clin. Epigenet."},{"issue":"6","key":"10.1016\/j.bbrc.2025.152891_bib31","doi-asserted-by":"crossref","first-page":"5522","DOI":"10.1021\/acsomega.2c06787","article-title":"Raman spectroscopy revealed cell passage-dependent distinct biochemical alterations in radiation-resistant breast cancer cells","volume":"8","author":"Rauniyar","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.bbrc.2025.152891_bib32","article-title":"Raman micro-spectroscopic map estimating in vivo precision of tumor ablative effect achieved by photothermal therapy procedure","volume":"37","author":"Mishra","year":"2021","journal-title":"Nanomedicine"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152891_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagen.2025.130771","article-title":"Analysis of lipids by Raman spectroscopy and mass spectrometry provides a detection tool and mechanistic insight into imatinib resistance in CML-BC","volume":"1869","author":"Bhat","year":"2025","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"issue":"10","key":"10.1016\/j.bbrc.2025.152891_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/cells10102506","article-title":"DNA fingerprint analysis of Raman spectra captures global genomic alterations in imatinib\u2010resistant chronic myeloid leukemia: a potential single assay for screening imatinib resistance","volume":"10","author":"Mojidra","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.bbrc.2025.152891_bib35","series-title":"Assay Guidance Manual [Internet]","article-title":"Authentication of Human and mouse cell lines by Short Tandem Repeat (STR) DNA genotype analysis. 2023 Jan 17","author":"Almeida","year":"2004"},{"key":"10.1016\/j.bbrc.2025.152891_bib36","series-title":"Phosphoacetylation of Histones During Cellular Transformation in Mammalian Cells","author":"Amnekar","year":"2021"},{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib37","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/s13148-025-01966-1","article-title":"The synergistic action of HDAC inhibitor with cisplatin impedes survival and proliferation of drug-tolerant persister in gastric and liver cancer cells","volume":"17","author":"Singh","year":"2025","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.bbrc.2025.152891_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbrc.2023.01.081","article-title":"Mitochondrial dysfunction and chromatin changes with autophagy-mediated survival in doxorubicin-resistant cancer cell lines","volume":"648","author":"Natu","year":"2023","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"18","key":"10.1016\/j.bbrc.2025.152891_bib39","doi-asserted-by":"crossref","DOI":"10.1039\/C5AY00954E","article-title":"Raman spectroscopy and cytopathology of oral exfoliated cells for oral cancer diagnosis","volume":"7","author":"Sahu","year":"2015","journal-title":"Anal. Methods"},{"issue":"3","key":"10.1016\/j.bbrc.2025.152891_bib40","doi-asserted-by":"crossref","DOI":"10.1214\/08-AOAS165","article-title":"Horseshoes in multidimensional scaling and local kernel methods","volume":"2","author":"Diaconis","year":"2008","journal-title":"Ann. Appl. Stat."},{"issue":"12","key":"10.1016\/j.bbrc.2025.152891_bib41","doi-asserted-by":"crossref","DOI":"10.1890\/0012-9658(2002)083[3331:RCATHE]2.0.CO;2","article-title":"Resemblance coefficients and the horseshoe effect in principal coordinates analysis","volume":"83","author":"Podani","year":"2002","journal-title":"Ecology"},{"issue":"4","key":"10.1016\/j.bbrc.2025.152891_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/cancers13040619","article-title":"The potential of Raman spectroscopy in the diagnosis of dysplastic and malignant oral lesions","volume":"13","author":"Ibrahim","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"5","key":"10.1016\/j.bbrc.2025.152891_bib43","doi-asserted-by":"crossref","DOI":"10.3390\/app12052419","article-title":"Raman spectroscopy of individual cervical exfoliated cells in premalignant and malignant lesions","volume":"12","author":"Silva-L\u00f3pez","year":"2022","journal-title":"Appl. Sci."},{"key":"10.1016\/j.bbrc.2025.152891_bib44","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1039\/C5FD00197H","article-title":"Raman spectroscopy for cytopathology of exfoliated cervical cells","volume":"187","author":"Ramos","year":"2016","journal-title":"Faraday Discuss"},{"issue":"6","key":"10.1016\/j.bbrc.2025.152891_bib45","doi-asserted-by":"crossref","DOI":"10.1529\/biophysj.103.038604","article-title":"Raman spectroscopy detects biochemical changes due to proliferation in mammalian cell cultures","volume":"88","author":"Short","year":"2005","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbrc.2025.152891_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2017.06.020","article-title":"Raman spectroscopy differentiates between sensitive and resistant multiple myeloma cell lines","volume":"187","author":"Franco","year":"2017","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"issue":"35","key":"10.1016\/j.bbrc.2025.152891_bib47","doi-asserted-by":"crossref","DOI":"10.1021\/acs.analchem.3c02073","article-title":"Monitoring metabolic changes in response to chemotherapies in cancer with raman spectroscopy and metabolomics","volume":"95","author":"Cutshaw","year":"2023","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.bbrc.2025.152891_bib48","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-022-32101-w","article-title":"Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells","volume":"13","author":"Tan","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbrc.2025.152891_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2023.101007","article-title":"Effective targeting of breast cancer by the inhibition of P-glycoprotein mediated removal of toxic lipid peroxidation byproducts from drug-tolerant persister cells","volume":"71","author":"Szeb\u00e9nyi","year":"2023","journal-title":"Drug Resist. Updates"},{"key":"10.1016\/j.bbrc.2025.152891_bib50","series-title":"Theranostics","first-page":"6261","article-title":"Epigenetics and metabolism at the crossroads of stress-induced plasticity, stemness, and therapeutic resistance in cancer","volume":"vol. 10","author":"Menon","year":"2020"},{"issue":"6","key":"10.1016\/j.bbrc.2025.152891_bib51","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1158\/0008-5472.CAN-14-2103","article-title":"Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation","volume":"75","author":"Chisholm","year":"2015","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.bbrc.2025.152891_bib52","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1021\/acs.jproteome.9b00773","article-title":"Proteomic analyses identify a novel role for EZH2 in the initiation of cancer cell drug tolerance","volume":"19","author":"Pham","year":"2020","journal-title":"J. Proteome Res."},{"issue":"2","key":"10.1016\/j.bbrc.2025.152891_bib53","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.ccell.2017.07.002","article-title":"Repression of stress-induced LINE-1 expression protects cancer cell subpopulations from lethal drug exposure","volume":"32","author":"Guler","year":"2017","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bbrc.2025.152891_bib54","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1038\/sj.bjc.6603024","article-title":"Epigenetics as a mechanism driving polygenic clinical drug resistance","volume":"94","author":"Glasspool","year":"2006","journal-title":"Br. J. Cancer"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X25016079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X25016079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:01:50Z","timestamp":1777384910000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X25016079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":54,"alternative-id":["S0006291X25016079"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.152891","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Raman spectroscopy for detecting gastric and liver cancer cells that entered a tolerant persistence state to survive cisplatin chemotherapy","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2025.152891","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"152891"}}