{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T08:53:35Z","timestamp":1781859215252,"version":"3.54.5"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012154","name":"Graduate Research and Innovation Projects of Jiangsu Province","doi-asserted-by":"publisher","award":["SJCX24 _2352"],"award-info":[{"award-number":["SJCX24 _2352"]}],"id":[{"id":"10.13039\/501100012154","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012154","name":"Graduate Research and Innovation Projects of Jiangsu Province","doi-asserted-by":"publisher","award":["SJCX23 _2029"],"award-info":[{"award-number":["SJCX23 _2029"]}],"id":[{"id":"10.13039\/501100012154","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014862","name":"Yangzhou Science and Technology Bureau","doi-asserted-by":"publisher","award":["YZ2023067"],"award-info":[{"award-number":["YZ2023067"]}],"id":[{"id":"10.13039\/501100014862","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007062","name":"Yangzhou University","doi-asserted-by":"publisher","award":["202102"],"award-info":[{"award-number":["202102"]}],"id":[{"id":"10.13039\/501100007062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.bbrc.2026.153408","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:25:15Z","timestamp":1770222315000},"page":"153408","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Neuroprotective effect of genistein nanoparticles on ischemic cerebral infarction"],"prefix":"10.1016","volume":"806","author":[{"given":"Linling","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gege","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1293-6549","authenticated-orcid":false,"given":"Yingge","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10471","key":"10.1016\/j.bbrc.2026.153408_bib1","first-page":"2543","article-title":"Global, regional, and national progress towards the 2030 global nutrition targets and forecasts to 2050: a systematic analysis for the global burden of disease Study 2021","volume":"404","year":"2025","journal-title":"Lancet"},{"issue":"10069","key":"10.1016\/j.bbrc.2026.153408_bib2","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0140-6736(16)30962-X","article-title":"Stroke","volume":"389","author":"Hankey","year":"2017","journal-title":"Lancet"},{"issue":"Pt B","key":"10.1016\/j.bbrc.2026.153408_bib3","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.neuropharm.2017.11.010","article-title":"Thrombolytic therapies for ischemic stroke: triumphs and future challenges","volume":"134","author":"Moussaddy","year":"2018","journal-title":"Neuropharmacology"},{"issue":"4","key":"10.1016\/j.bbrc.2026.153408_bib4","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s40264-022-01147-6","article-title":"Intracranial hemorrhage following anticoagulant treatment in Denmark: spontaneous adverse drug reaction reports versus real-world data","volume":"45","author":"von Osmanski","year":"2022","journal-title":"Drug Saf."},{"key":"10.1016\/j.bbrc.2026.153408_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113518","article-title":"Emerging neuroprotective strategies for the treatment of ischemic stroke: an overview of clinical and preclinical studies","volume":"335","author":"Paul","year":"2021","journal-title":"Exp. Neurol."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153408_bib6","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/s41573-020-00114-z","article-title":"Natural products in drug discovery: advances and opportunities","volume":"20","author":"Atanasov","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153408_bib7","doi-asserted-by":"crossref","DOI":"10.1002\/ardp.202400865","article-title":"Advances in the activity of resveratrol and its derivatives in cardiovascular diseases","volume":"358","author":"Peng","year":"2025","journal-title":"Arch Pharm (Weinheim)"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153408_bib8","first-page":"21","article-title":"Research progress of small-molecule natural medicines for the treatment of ischemic stroke","volume":"23","author":"Liu","year":"2025","journal-title":"Chin. J. Nat. Med."},{"issue":"10","key":"10.1016\/j.bbrc.2026.153408_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27103099","article-title":"The signaling pathways and targets of natural compounds from traditional Chinese medicine in treating ischemic stroke","volume":"27","author":"Li","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.bbrc.2026.153408_bib10","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.pneurobio.2017.10.001","article-title":"Blood-brain barrier dysfunction and recovery after ischemic stroke","volume":"163\u2013164","author":"Jiang","year":"2018","journal-title":"Prog Neurobiol"},{"issue":"11","key":"10.1016\/j.bbrc.2026.153408_bib11","first-page":"1131","article-title":"Inhibitory effect of genistein on activation of STAT3 induced by brain ischemia\/reperfusion in rat hippocampus","volume":"24","author":"Li","year":"2003","journal-title":"Acta Pharmacol. Sin."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153408_bib12","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1038\/s41598-025-88136-8","article-title":"Gen inhibiting the Wnt\/Ca(2+) signaling pathway alleviates cerebral ischemia\/reperfusion injury","volume":"15","author":"Li","year":"2025","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153408_bib13","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.7150\/ijbs.56800","article-title":"Genistein-3'-sodium sulfonate attenuates neuroinflammation in stroke rats by down-regulating microglial M1 polarization through \u03b17nAChR-NF-\u03baB signaling pathway","volume":"17","author":"Liu","year":"2021","journal-title":"Int. J. Biol. Sci."},{"issue":"39","key":"10.1016\/j.bbrc.2026.153408_bib14","doi-asserted-by":"crossref","first-page":"11676","DOI":"10.1021\/acs.jafc.1c02898","article-title":"Evaluation of blood-brain barrier permeability of polyphenols, anthocyanins, and their metabolites","volume":"69","author":"Shimazu","year":"2021","journal-title":"J. Agric. Food Chem."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153408_bib15","first-page":"426","article-title":"Nanospray drying as a novel tool to improve technological properties of soy isoflavone extracts","volume":"83","author":"Del Gaudio","year":"2017","journal-title":"Planta Med."},{"key":"10.1016\/j.bbrc.2026.153408_bib16","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jconrel.2019.02.031","article-title":"Emerging paradigms in nanotechnology for imaging and treatment of cerebral ischemia","volume":"300","author":"Kaviarasi","year":"2019","journal-title":"J Control Release"},{"issue":"Database issue","key":"10.1016\/j.bbrc.2026.153408_bib17","doi-asserted-by":"crossref","first-page":"D447","DOI":"10.1093\/nar\/gku1003","article-title":"STRING v10: protein-protein interaction networks, integrated over the tree of life","volume":"43","author":"Szklarczyk","year":"2015","journal-title":"Nucleic Acids Res."},{"issue":"11","key":"10.1016\/j.bbrc.2026.153408_bib18","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153408_bib19","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1161\/01.STR.20.1.84","article-title":"Reversible middle cerebral artery occlusion without craniectomy in rats","volume":"20","author":"Longa","year":"1989","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153408_bib20","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1186\/s12915-023-01679-y","article-title":"Four-parameter analysis in modified Rotarod test for detecting minor motor deficits in mice","volume":"21","author":"Shan","year":"2023","journal-title":"BMC Biol."},{"issue":"10","key":"10.1016\/j.bbrc.2026.153408_bib21","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1161\/01.STR.0000032302.91894.0F","article-title":"Behavioral tests after intracerebral hemorrhage in the rat","volume":"33","author":"Hua","year":"2002","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.bbrc.2026.153408_bib22","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.hest.2020.09.001","article-title":"Behavioral tests in rodent models of stroke","volume":"1","author":"Ruan","year":"2020","journal-title":"Brain Hemorrhages"},{"issue":"8","key":"10.1016\/j.bbrc.2026.153408_bib23","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1161\/01.STR.25.8.1658","article-title":"Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats","volume":"25","author":"Yang","year":"1994","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153408_bib24","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jneumeth.2004.04.029","article-title":"Infarct volume quantification in mouse focal cerebral ischemia: a comparison of triphenyltetrazolium chloride and cresyl violet staining techniques","volume":"139","author":"T\u00fcreyen","year":"2004","journal-title":"J. Neurosci. Methods"},{"issue":"5","key":"10.1016\/j.bbrc.2026.153408_bib25","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.2100","article-title":"Study on the neuroprotective effects of Genistein on Alzheimer's disease","volume":"11","author":"Duan","year":"2021","journal-title":"Brain Behav"},{"issue":"Pt A","key":"10.1016\/j.bbrc.2026.153408_bib26","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.physbeh.2015.08.037","article-title":"Is genistein neuroprotective in traumatic brain injury?","volume":"152","author":"Soltani","year":"2015","journal-title":"Physiol. Behav."},{"issue":"9","key":"10.1016\/j.bbrc.2026.153408_bib27","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke Statistics-2020 update: a report from the American heart Association","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.bbrc.2026.153408_bib28","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S1474-4422(21)00252-0","article-title":"Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the global Burden of Disease Study 2019","volume":"20","year":"2021","journal-title":"Lancet Neurol."},{"issue":"14","key":"10.1016\/j.bbrc.2026.153408_bib29","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1056\/NEJMoa2213379","article-title":"Trial of endovascular therapy for acute ischemic stroke with large infarct","volume":"388","author":"Huo","year":"2023","journal-title":"N. Engl. J. Med."},{"issue":"10","key":"10.1016\/j.bbrc.2026.153408_bib30","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1161\/STROKEAHA.123.044123","article-title":"Neurovascular inflammation and complications of thrombolysis therapy in stroke","volume":"54","author":"Liu","year":"2023","journal-title":"Stroke"},{"key":"10.1016\/j.bbrc.2026.153408_bib31","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jconrel.2016.05.044","article-title":"Nanoparticle-mediated brain drug delivery: overcoming blood-brain barrier to treat neurodegenerative diseases","volume":"235","author":"Saraiva","year":"2016","journal-title":"J Control Release"},{"key":"10.1016\/j.bbrc.2026.153408_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.102040","article-title":"Constituent isoflavones of Puerariae radix as a potential neuroprotector in cognitive impairment: evidence from preclinical studies","volume":"90","author":"Ren","year":"2023","journal-title":"Ageing Res. Rev."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153408_bib33","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1080\/1028415X.2017.1391933","article-title":"Genistein: mechanisms of action for a pleiotropic neuroprotective agent in stroke","volume":"22","author":"Schreihofer","year":"2019","journal-title":"Nutr. Neurosci."},{"issue":"7","key":"10.1016\/j.bbrc.2026.153408_bib34","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/hipo.22126","article-title":"Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS\/Nrf2\/HO-1 signaling","volume":"23","author":"Wang","year":"2013","journal-title":"Hippocampus"},{"issue":"12","key":"10.1016\/j.bbrc.2026.153408_bib35","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/nnano.2007.387","article-title":"Nanocarriers as an emerging platform for cancer therapy","volume":"2","author":"Peer","year":"2007","journal-title":"Nat. Nanotechnol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153408_bib36","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/s41392-023-01642-x","article-title":"Smart nanoparticles for cancer therapy","volume":"8","author":"Sun","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153408_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.drudis.2022.103454","article-title":"Production of nanostructured systems: main and innovative techniques","volume":"28","author":"Zimmermann","year":"2023","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.bbrc.2026.153408_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.112836","article-title":"Formononetin protects against inflammation associated with cerebral ischemia-reperfusion injury in rats by targeting the JAK2\/STAT3 signaling pathway","volume":"149","author":"Yu","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbrc.2026.153408_bib39","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.neuroscience.2024.06.026","article-title":"Glycyrrhetinic acid triggers a protective autophagy by inhibiting the JAK2\/STAT3 pathway in cerebral ischemia\/reperfusion injury","volume":"554","author":"Liang","year":"2024","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbrc.2026.153408_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153745","article-title":"Genistein-3'-sodium sulfonate ameliorates cerebral ischemia injuries by blocking neuroinflammation through the \u03b17nAChR-JAK2\/STAT3 signaling pathway in rats","volume":"93","author":"Xie","year":"2021","journal-title":"Phytomedicine"},{"issue":"10","key":"10.1016\/j.bbrc.2026.153408_bib41","doi-asserted-by":"crossref","first-page":"7930","DOI":"10.1007\/s12035-024-04039-1","article-title":"Targeting PI3K\/Akt in cerebral ischemia reperfusion injury alleviation: from signaling networks to targeted therapy","volume":"61","author":"Zheng","year":"2024","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbrc.2026.153408_bib42","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jep.2016.01.028","article-title":"PI3K\/Akt pathway contributes to neuroprotective effect of Tongxinluo against focal cerebral ischemia and reperfusion injury in rats","volume":"181","author":"Yu","year":"2016","journal-title":"J. Ethnopharmacol."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153408_bib43","doi-asserted-by":"crossref","first-page":"389","DOI":"10.4149\/gpb_2019024","article-title":"A preliminary report: genistein attenuates cerebral ischemia injury in ovariectomized rats via regulation of the PI3K-Akt-mTOR pathway","volume":"38","author":"Lu","year":"2019","journal-title":"Gen. Physiol. Biophys."},{"issue":"8","key":"10.1016\/j.bbrc.2026.153408_bib44","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.3109\/13880209.2014.962057","article-title":"Protection by genistein on cortical neurons against oxidative stress injury via inhibition of NF-kappaB, JNK and ERK signaling pathway","volume":"53","author":"Qian","year":"2015","journal-title":"Pharm. Biol."},{"issue":"9","key":"10.1016\/j.bbrc.2026.153408_bib45","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/nri.2017.52","article-title":"The non-canonical NF-\u03baB pathway in immunity and inflammation","volume":"17","author":"Sun","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbrc.2026.153408_bib46","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.fct.2014.08.019","article-title":"Anti-inflammatory effect of gamma-irradiated genistein through inhibition of NF-\u03baB and MAPK signaling pathway in lipopolysaccharide-induced macrophages","volume":"74","author":"Byun","year":"2014","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.bbrc.2026.153408_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.820969","article-title":"Genistein: a review on its anti-inflammatory properties","volume":"13","author":"Goh","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153408_bib48","doi-asserted-by":"crossref","DOI":"10.3390\/biom13040702","article-title":"VEGFA isoforms as pro-angiogenic therapeutics for cerebrovascular diseases","volume":"13","author":"White","year":"2023","journal-title":"Biomolecules"},{"issue":"9","key":"10.1016\/j.bbrc.2026.153408_bib49","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1038\/aps.2017.28","article-title":"Amyloid beta: structure, biology and structure-based therapeutic development","volume":"38","author":"Chen","year":"2017","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.bbrc.2026.153408_bib50","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3389\/fnmol.2017.00022","article-title":"APP as a protective factor in acute neuronal insults","volume":"10","author":"Hefter","year":"2017","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.bbrc.2026.153408_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2022.154179","article-title":"High FN1 expression correlates with gastric cancer progression","volume":"239","author":"Li","year":"2022","journal-title":"Pathol. Res. Pract."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153408_bib52","doi-asserted-by":"crossref","DOI":"10.1002\/jcp.31216","article-title":"Role of c-Fos in DNA damage repair","volume":"239","author":"Yao","year":"2024","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.bbrc.2026.153408_bib53","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cytogfr.2024.06.002","article-title":"The impact of cytokines in neuroinflammation-mediated stroke","volume":"78","author":"Kumari","year":"2024","journal-title":"Cytokine Growth Factor Rev."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153408_bib54","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1161\/STROKEAHA.122.036946","article-title":"Neuroinflammation, stroke, blood-brain barrier dysfunction, and imaging modalities","volume":"53","author":"Candelario-Jalil","year":"2022","journal-title":"Stroke"},{"issue":"9","key":"10.1016\/j.bbrc.2026.153408_bib55","doi-asserted-by":"crossref","first-page":"6161","DOI":"10.1007\/s12035-024-03939-6","article-title":"Crosstalk among glial cells in the blood-brain barrier injury after ischemic stroke","volume":"61","author":"Lu","year":"2024","journal-title":"Mol. Neurobiol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153408_bib56","doi-asserted-by":"crossref","first-page":"C135","DOI":"10.1152\/ajpcell.00136.2018","article-title":"Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke","volume":"316","author":"Yang","year":"2019","journal-title":"Am J Physiol Cell Physiol"},{"issue":"3","key":"10.1016\/j.bbrc.2026.153408_bib57","doi-asserted-by":"crossref","first-page":"C343","DOI":"10.1152\/ajpcell.00095.2018","article-title":"Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection","volume":"315","author":"Abdullahi","year":"2018","journal-title":"Am J Physiol Cell Physiol"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26001725?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26001725?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T08:20:17Z","timestamp":1781857217000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X26001725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":57,"alternative-id":["S0006291X26001725"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.153408","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroprotective effect of genistein nanoparticles on ischemic cerebral infarction","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.153408","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"153408"}}