{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:28:57Z","timestamp":1793158137342,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015397","name":"Inner Mongolia Autonomous Region Department of Science and Technology","doi-asserted-by":"publisher","award":["2021ZY0010"],"award-info":[{"award-number":["2021ZY0010"]}],"id":[{"id":"10.13039\/501100015397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82160320"],"award-info":[{"award-number":["82160320"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004767","name":"University of Science and Technology Liaoning","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004767","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.bbrc.2026.153503","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:10:41Z","timestamp":1771546241000},"page":"153503","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Allicin improves motor neuron survival in amyotrophic lateral sclerosis by reducing neuroinflammation and modulating gut microbiota"],"prefix":"10.1016","volume":"809","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7573-1619","authenticated-orcid":false,"given":"Ying","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanchao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranran","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sutian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2026.153503_bib1","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/S0140-6736(22)01272-7","article-title":"Amyotrophic lateral sclerosis","volume":"400","author":"Feldman","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.bbrc.2026.153503_bib2","article-title":"ALS molecular subtypes are a combination of cellular and pathological features learned by deep multiomics classifiers","volume":"44","author":"O'Neill","year":"2025","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbrc.2026.153503_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/antiox11040614","article-title":"SOD1 in ALS: taking stock in pathogenic mechanisms and the role of glial and muscle cells","volume":"11","author":"Peggion","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbrc.2026.153503_bib4","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/nrneurol.2011.152","article-title":"Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis","volume":"7","author":"Ferraiuolo","year":"2011","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.bbrc.2026.153503_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/antiox10071012","article-title":"Amyotrophic lateral sclerosis: molecular mechanisms, biomarkers, and therapeutic strategies","volume":"10","author":"Yang","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbrc.2026.153503_bib6","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s11481-009-9171-5","article-title":"Microglia in ALS: the good, the bad, and the resting","volume":"4","author":"Henkel","year":"2009","journal-title":"J. Neuroimmune Pharmacol."},{"key":"10.1016\/j.bbrc.2026.153503_bib7","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s40035-018-0138-4","article-title":"Dynamic changes of CX3CL1\/CX3CR1 axis during microglial activation and motor neuron loss in the spinal cord of ALS mouse model","volume":"7","author":"Zhang","year":"2018","journal-title":"Transl. Neurodegener."},{"key":"10.1016\/j.bbrc.2026.153503_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26083854","article-title":"Neuroinflammation and amyotrophic lateral sclerosis: recent advances in anti-inflammatory cytokines as therapeutic strategies","volume":"26","author":"Stacchiotti","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2026.153503_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms8050784","article-title":"The role of the microbiota-gut-brain axis and antibiotics in ALS and neurodegenerative diseases","volume":"8","author":"Obrenovich","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.bbrc.2026.153503_bib10","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2013.54","article-title":"Minocycline selectively inhibits M1 polarization of microglia","volume":"4","author":"Kobayashi","year":"2013","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbrc.2026.153503_bib11","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/417074a","article-title":"Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice","volume":"417","author":"Zhu","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2026.153503_bib12","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/nature03180","article-title":"Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression","volume":"433","author":"Rothstein","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2026.153503_bib13","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2021.1996848","article-title":"Aberrant enteric neuromuscular system and dysbiosis in amyotrophic lateral sclerosis","volume":"13","author":"Zhang","year":"2021","journal-title":"Gut Microbes"},{"key":"10.1016\/j.bbrc.2026.153503_bib14","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S1474-4422(14)70222-4","article-title":"Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial","volume":"13","author":"Cudkowicz","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbrc.2026.153503_bib15","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.3389\/fmicb.2016.01479","article-title":"Evaluation of the microbial diversity in amyotrophic lateral sclerosis using high-throughput sequencing","volume":"7","author":"Fang","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bbrc.2026.153503_bib16","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1097\/CM9.0000000000000351","article-title":"Intestinal microbiota composition in patients with amyotrophic lateral sclerosis: establishment of bacterial and archaeal communities analyses","volume":"132","author":"Zhai","year":"2019","journal-title":"Chin. Med. J. (Engl.)."},{"key":"10.1016\/j.bbrc.2026.153503_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/biom11091292","article-title":"Gut microbiota as a potential player in Mn-Induced neurotoxicity","volume":"11","author":"Tinkov","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.bbrc.2026.153503_bib18","article-title":"Leaky intestine and impaired microbiome in an amyotrophic lateral sclerosis mouse model","volume":"3","author":"Wu","year":"2015","journal-title":"Phys. Rep."},{"key":"10.1016\/j.bbrc.2026.153503_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2023.1133546","article-title":"Modulation of the gut-brain axis via the gut microbiota: a new era in treatment of amyotrophic lateral sclerosis","volume":"14","author":"Hong","year":"2023","journal-title":"Front. Neurol."},{"key":"10.1016\/j.bbrc.2026.153503_bib20","doi-asserted-by":"crossref","first-page":"8363","DOI":"10.1021\/jf301298y","article-title":"Allicin induces p53-mediated autophagy in Hep G2 human liver cancer cells","volume":"60","author":"Chu","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbrc.2026.153503_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/antiox11010087","article-title":"Allicin, an antioxidant and neuroprotective agent, ameliorates cognitive impairment","volume":"11","author":"Nadeem","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbrc.2026.153503_bib22","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.tice.2017.11.002","article-title":"Allicin ameliorates cognitive impairment in APP\/PS1 mice via suppressing oxidative stress by blocking JNK signaling pathways","volume":"50","author":"Zhang","year":"2018","journal-title":"Tissue Cell"},{"key":"10.1016\/j.bbrc.2026.153503_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/nu11122909","article-title":"Allicin improves metabolism in high-fat diet-induced Obese mice by modulating the gut microbiota","volume":"11","author":"Shi","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.bbrc.2026.153503_bib24","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/s41586-019-1443-5","article-title":"Potential roles of gut microbiome and metabolites in modulating ALS in mice","volume":"572","author":"Blacher","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.bbrc.2026.153503_bib25","article-title":"Diallyl disulfide (DADS) ameliorates intestinal Candida albicans infection by modulating the gut microbiota and metabolites and providing intestinal protection in mice","volume":"11","author":"Hu","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bbrc.2026.153503_bib26","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1159\/000430271","article-title":"Allicin protects PC12 cells against 6-OHDA-Induced oxidative stress and mitochondrial dysfunction via regulating mitochondrial dynamics","volume":"36","author":"Liu","year":"2015","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.bbrc.2026.153503_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176555","article-title":"Corrigendum to \"Allicin improves endoplasmic reticulum stress-related cognitive deficits via PERK\/Nrf2 antioxidative signaling pathway\" [Europ. J. Pharmacol. 762 (2015) 239-246]","volume":"971","author":"Zhu","year":"2024","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bbrc.2026.153503_bib28","article-title":"Correction: Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis","volume":"17","author":"Zhao","year":"2025","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.bbrc.2026.153503_bib29","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41522-022-00266-3","article-title":"Atherosclerosis amelioration by allicin in raw garlic through gut microbiota and trimethylamine-N-oxide modulation","volume":"8","author":"Panyod","year":"2022","journal-title":"npj Biofilms Microbiomes"},{"key":"10.1016\/j.bbrc.2026.153503_bib30","doi-asserted-by":"crossref","first-page":"19207","DOI":"10.1021\/acs.jafc.3c05602","article-title":"Bioavailability, health benefits, and delivery systems of allicin: a review","volume":"71","author":"Deng","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbrc.2026.153503_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073846","article-title":"Early changes of neuromuscular transmission in the SOD1(G93A) mice model of ALS start long before motor symptoms onset","volume":"8","author":"Rocha","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbrc.2026.153503_bib32","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s11064-006-9166-z","article-title":"Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis","volume":"31","author":"Xu","year":"2006","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bbrc.2026.153503_bib33","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1111\/cns.12855","article-title":"Repurposing carbamazepine for the treatment of amyotrophic lateral sclerosis in SOD1-G93A mouse model","volume":"24","author":"Zhang","year":"2018","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.bbrc.2026.153503_bib34","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s40035-020-00221-2","article-title":"Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes","volume":"9","author":"Kwon","year":"2020","journal-title":"Transl. Neurodegener."},{"key":"10.1016\/j.bbrc.2026.153503_bib35","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.expneurol.2003.10.004","article-title":"Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man","volume":"185","author":"Fischer","year":"2004","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbrc.2026.153503_bib36","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1073\/pnas.1314826111","article-title":"ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation","volume":"111","author":"Seijffers","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbrc.2026.153503_bib37","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.4103\/1673-5374.308077","article-title":"Axonal regeneration and sprouting as a potential therapeutic target for nervous system disorders","volume":"16","author":"Marshall","year":"2021","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.bbrc.2026.153503_bib38","doi-asserted-by":"crossref","first-page":"747","DOI":"10.4103\/1673-5374.382226","article-title":"Skeletal muscle as a molecular and cellular biomarker of disease progression in amyotrophic lateral sclerosis: a narrative review","volume":"19","author":"King","year":"2024","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.bbrc.2026.153503_bib39","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1038\/s41418-018-0060-4","article-title":"Exploring the genetics and non-cell autonomous mechanisms underlying ALS\/FTLD","volume":"25","author":"Chen","year":"2018","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbrc.2026.153503_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113259","article-title":"Increased activation ability of monocytes from ALS patients","volume":"328","author":"Du","year":"2020","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbrc.2026.153503_bib41","doi-asserted-by":"crossref","first-page":"39625","DOI":"10.1007\/s11356-021-13392-w","article-title":"Allicin mitigates hepatic injury following cyclophosphamide administration via activation of Nrf2\/ARE pathways and through inhibition of inflammatory and apoptotic machinery","volume":"28","author":"Sun","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"Suppl 2","key":"10.1016\/j.bbrc.2026.153503_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000512226","article-title":"The gut-brain axis","volume":"77","author":"Hattori","year":"2021","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.bbrc.2026.153503_bib43","article-title":"Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice","volume":"13","author":"Figueroa-Romero","year":"2019","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.bbrc.2026.153503_bib44","doi-asserted-by":"crossref","first-page":"12837","DOI":"10.1021\/acs.jafc.1c05014","article-title":"Allicin ameliorates intestinal barrier damage via microbiota-regulated short-chain fatty Acids-TLR4\/MyD88\/NF-\u03baB Cascade response in acrylamide-induced rats","volume":"69","author":"Yuan","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbrc.2026.153503_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mib.2017.07.003","article-title":"Dysbiotic proteobacteria expansion: a microbial signature of epithelial dysfunction","volume":"39","author":"Litvak","year":"2017","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.bbrc.2026.153503_bib46","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2363014","article-title":"Modulation of Alzheimer's disease brain pathology in mice by gut bacterial depletion: the role of IL-17a","volume":"16","author":"Hao","year":"2024","journal-title":"Gut Microbes"},{"key":"10.1016\/j.bbrc.2026.153503_bib47","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1186\/s40168-021-01172-0","article-title":"A fiber-deprived diet causes cognitive impairment and hippocampal microglia-mediated synaptic loss through the gut microbiota and metabolites","volume":"9","author":"Shi","year":"2021","journal-title":"Microbiome"},{"key":"10.1016\/j.bbrc.2026.153503_bib48","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/s41575-019-0157-3","article-title":"The role of short-chain fatty acids in microbiota-gut-brain communication","volume":"16","author":"Dalile","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.bbrc.2026.153503_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2021.111376","article-title":"Neuroprotective effects of short-chain fatty acids in MPTP induced mice model of Parkinson's disease","volume":"150","author":"Hou","year":"2021","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.bbrc.2026.153503_bib50","doi-asserted-by":"crossref","DOI":"10.3390\/nu16162660","article-title":"Exploration of the muribaculaceae family in the gut microbiota: diversity, metabolism, and function","volume":"16","author":"Zhu","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.bbrc.2026.153503_bib51","doi-asserted-by":"crossref","first-page":"12184","DOI":"10.1021\/acs.jafc.4c01922","article-title":"Gut microbiota mediate the neuroprotective effect of Oolong tea polyphenols in cognitive impairment induced by circadian rhythm disorder","volume":"72","author":"Song","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbrc.2026.153503_bib52","first-page":"592","volume":"24","author":"Sibai","year":"2020"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26002676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26002676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:31:46Z","timestamp":1777426306000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X26002676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":52,"alternative-id":["S0006291X26002676"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.153503","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Allicin improves motor neuron survival in amyotrophic lateral sclerosis by reducing neuroinflammation and modulating gut microbiota","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.153503","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"153503"}}