{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T06:26:24Z","timestamp":1793600784079,"version":"4.5.0"},"reference-count":177,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,3,30]],"date-time":"2027-03-30T00:00:00Z","timestamp":1806364800000},"content-version":"am","delay-in-days":333,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100008788","name":"College of Veterinary Medicine, Ohio State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008788","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P20 GM103648"],"award-info":[{"award-number":["P20 GM103648"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.bbrc.2026.153676","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T23:44:33Z","timestamp":1774395873000},"page":"153676","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Class III facilitative glucose transporters: Beyond glucose transport in health and disease"],"prefix":"10.1016","volume":"815","author":[{"given":"V.A.","family":"Lacombe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Campolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rochowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Beets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2026.153676_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/409547","article-title":"Expression and regulation of facilitative glucose transporters in equine insulin-sensitive tissue: from physiology to pathology","volume":"2014","author":"Lacombe","year":"2014","journal-title":"ISRN Veterinary Science"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib2","doi-asserted-by":"crossref","first-page":"E141","DOI":"10.1152\/ajpendo.00712.2009","article-title":"Glucose transporters in the 21st Century","volume":"298","author":"Thorens","year":"2010","journal-title":"Am. J. Physiol. Endocrinol. Metabol."},{"issue":"12","key":"10.1016\/j.bbrc.2026.153676_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0146033","article-title":"Diabetes alters the expression and translocation of the insulin-sensitive glucose transporters 4 and 8 in the atria","volume":"10","author":"Maria","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib4","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1007\/s00424-020-02444-8","article-title":"Glucose transporters in cardiovascular system in health and disease","volume":"472","author":"Bertrand","year":"2020","journal-title":"Pflueg. Arch. Eur. J. Physiol."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib5","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3390\/metabo14050267","article-title":"Diabetes causes significant alterations in pulmonary glucose transporter expression","volume":"14","author":"Campolo","year":"2024","journal-title":"Metabolites"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib6","doi-asserted-by":"crossref","first-page":"F205","DOI":"10.1152\/ajprenal.00237.2004","article-title":"Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy","volume":"290","author":"Linden","year":"2006","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40170-021-00248-7","article-title":"A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism","volume":"9","author":"Shriwas","year":"2021","journal-title":"Cancer Metabol."},{"issue":"20","key":"10.1016\/j.bbrc.2026.153676_bib8","doi-asserted-by":"crossref","first-page":"5832","DOI":"10.1158\/0008-5472.CAN-14-0254","article-title":"Metabolic vulnerabilities in endometrial cancer","volume":"74","author":"Byrne","year":"2014","journal-title":"Cancer Res."},{"issue":"15","key":"10.1016\/j.bbrc.2026.153676_bib9","doi-asserted-by":"crossref","first-page":"8142","DOI":"10.3390\/ijms22158142","article-title":"Brain glucose transporters: role in pathogenesis and potential targets for the treatment of alzheimer's disease","volume":"22","author":"Szablewski","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2026.153676_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2024.1344039","article-title":"Bridging the gap: glucose transporters, Alzheimer's, and future therapeutic prospects","volume":"12","author":"Albaik","year":"2024","journal-title":"Front. Cell Dev. Biol."},{"issue":"16","key":"10.1016\/j.bbrc.2026.153676_bib11","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1161\/01.CIR.0000034049.61181.F3","article-title":"Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice","volume":"106","author":"Liao","year":"2002","journal-title":"Circulation"},{"issue":"15","key":"10.1016\/j.bbrc.2026.153676_bib12","doi-asserted-by":"crossref","first-page":"8698","DOI":"10.3390\/ijms23158698","article-title":"Importance of GLUT transporters in disease diagnosis and treatment","volume":"23","author":"Ismail","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"2\u20133","key":"10.1016\/j.bbrc.2026.153676_bib13","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.mam.2012.07.001","article-title":"The SLC2 (GLUT) family of membrane transporters","volume":"34","author":"Mueckler","year":"2013","journal-title":"Mol. Aspect. Med."},{"issue":"7503","key":"10.1016\/j.bbrc.2026.153676_bib14","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nature13306","article-title":"Crystal structure of the human glucose transporter GLUT1","volume":"510","author":"Deng","year":"2014","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib15","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.cmet.2007.03.006","article-title":"The GLUT4 glucose transporter","volume":"5","author":"Huang","year":"2007","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbrc.2026.153676_bib16","article-title":"Structure of, and functional insight into the GLUT family of membrane transporters","volume":"167","author":"Cheeseman","year":"2015","journal-title":"Cell Health Cytoskeleton"},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib17","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/iub.315","article-title":"The protein family of glucose transport facilitators: it's not only about glucose after all","volume":"62","author":"Augustin","year":"2010","journal-title":"IUBMB Life"},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib18","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1007\/s00424-020-02411-3","article-title":"Structure, function and regulation of mammalian glucose transporters of the SLC2 family","volume":"472","author":"Holman","year":"2020","journal-title":"Pflueg. Arch. Eur. J. Physiol."},{"issue":"Pt 2","key":"10.1016\/j.bbrc.2026.153676_bib19","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1042\/bj3580517","article-title":"Targeting of GLUT6 (formerly GLUT9) and GLUT8 in rat adipose cells","volume":"358","author":"Lisinski","year":"2001","journal-title":"Biochem. J."},{"issue":"D1","key":"10.1016\/j.bbrc.2026.153676_bib20","doi-asserted-by":"crossref","first-page":"D609","DOI":"10.1093\/nar\/gkae1010","article-title":"UniProt: the Universal Protein Knowledgebase in 2025","volume":"53","author":"The UniProt Consortium","year":"2025","journal-title":"Nucleic Acids Res."},{"issue":"Pt 3","key":"10.1016\/j.bbrc.2026.153676_bib21","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1042\/bj3500771","article-title":"Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes","volume":"350","author":"Doege","year":"2000","journal-title":"Biochem. J."},{"issue":"17","key":"10.1016\/j.bbrc.2026.153676_bib22","doi-asserted-by":"crossref","first-page":"9798","DOI":"10.3390\/ijms23179798","article-title":"Investigating the expression and function of the glucose transporter GLUT6 in obesity","volume":"23","author":"Chen","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbrc.2026.153676_bib23","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.ygyno.2016.04.456","article-title":"Postmenopausal endometrial cancer patients have significantly higher expression of GLUT6 in the endometrium","volume":"141","author":"Baker","year":"2016","journal-title":"Gynecol. Oncol."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib24","doi-asserted-by":"crossref","first-page":"C574","DOI":"10.1152\/ajpcell.00275.2012","article-title":"Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells","volume":"304","author":"Pyla","year":"2013","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib25","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s12964-022-00915-2","article-title":"Slc2a6 regulates myoblast differentiation by targeting LDHB","volume":"20","author":"Jiang","year":"2022","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.bbrc.2026.153676_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2020.109688","article-title":"The NF-\u03baB signalling pathway regulates GLUT6 expression in endometrial cancer","volume":"73","author":"Caruana","year":"2020","journal-title":"Cell. Signal."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib27","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s10120-015-0577-x","article-title":"Glucose transporters 1, 3, 6, and 10 are expressed in gastric cancer and glucose transporter 3 is associated with UICC stage and survival","volume":"20","author":"Schl\u00f6\u00dfer","year":"2017","journal-title":"Gastric Cancer: Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association"},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib28","doi-asserted-by":"crossref","first-page":"718","DOI":"10.3390\/metabo13060718","article-title":"Novel expression of GLUT3, GLUT6 and GLUT10 in Equine gluteal muscle following glycogen-depleting exercise: impact of dietary starch and fat","volume":"13","author":"Valberg","year":"2023","journal-title":"Metabolites"},{"key":"10.1016\/j.bbrc.2026.153676_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cbpa.2018.02.015","article-title":"Expression profile of glucose transport-related genes under chronic and acute exposure to growth hormone in zebrafish","volume":"221","author":"Dalmolin","year":"2018","journal-title":"Comp. Biochem. Physiol. Mol. Integr. Physiol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib30","doi-asserted-by":"crossref","first-page":"E286","DOI":"10.1152\/ajpendo.00082.2018","article-title":"Knockout of glucose transporter GLUT6 has minimal effects on whole body metabolic physiology in mice","volume":"315","author":"Byrne","year":"2018","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib31","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1177\/1479164118780799","article-title":"Diabetes mellitus and abdominal aortic aneurysms: a review of the mechanisms underlying the negative relationship","volume":"15","author":"Dattani","year":"2018","journal-title":"Diabetes Vasc. Dis. Res."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib32","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.4049\/jimmunol.1801063","article-title":"Characterization of glucose transporter 6 in lipopolysaccharide-induced bone marrow-derived macrophage function","volume":"202","author":"Caruana","year":"2019","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib33","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/1873-3468.13298","article-title":"GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates glycolysis in macrophages","volume":"593","author":"Maedera","year":"2019","journal-title":"FEBS Letters"},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib34","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3390\/v10030114","article-title":"Upregulation of glucose uptake and hexokinase activity of primary human CD4+ T cells in response to infection with HIV-1","volume":"10","author":"Kavanagh Williamson","year":"2018","journal-title":"Viruses"},{"issue":"21","key":"10.1016\/j.bbrc.2026.153676_bib35","doi-asserted-by":"crossref","first-page":"16275","DOI":"10.1074\/jbc.275.21.16275","article-title":"GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity","volume":"275","author":"Doege","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.bbrc.2026.153676_bib36","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1111\/j.1600-0854.2005.00354.x","article-title":"GLUT8 contains a [DE]XXXL[LI] sorting motif and localizes to a late endosomal\/lysosomal compartment","volume":"6","author":"Augustin","year":"2005","journal-title":"Traffic (Copenhagen, Denmark)"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib37","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.brainres.2004.01.044","article-title":"Biphasic effects of stress upon GLUT8 glucose transporter expression and trafficking in the diabetic rat hippocampus","volume":"1006","author":"Piroli","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.bbrc.2026.153676_bib38","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.biochi.2019.10.014","article-title":"Protective role of adiponectin against testicular impairment in high-fat diet\/streptozotocin-induced type 2 diabetic mice","volume":"168","author":"Choubey","year":"2020","journal-title":"Biochimie"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib39","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s00441-001-0499-2","article-title":"The glucose transport facilitator GLUT8 is predominantly associated with the acrosomal region of mature spermatozoa","volume":"307","author":"Sch\u00fcrmann","year":"2002","journal-title":"Cell Tissue Res."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib40","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1530\/rep.1.00750","article-title":"Differential expression of glucose transporter GLUT8 during mouse spermatogenesis","volume":"131","author":"G\u00f3mez","year":"2006","journal-title":"Reproduction (Cambridge, England)"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib41","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jcjd.2017.04.008","article-title":"Placental expression of glucose transporter proteins in pregnancies complicated by gestational and pregestational diabetes mellitus","volume":"42","author":"Stanirowski","year":"2018","journal-title":"Can. J. Diabetes"},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib42","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3390\/cells13050391","volume":"13","author":"Lipka","year":"2024","journal-title":"tro Cells"},{"issue":"7","key":"10.1016\/j.bbrc.2026.153676_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.115962","article-title":"ANGPTL3 orchestrates hepatic fructose sensing and metabolism","volume":"44","author":"Zhao","year":"2025","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib44","doi-asserted-by":"crossref","first-page":"F186","DOI":"10.1152\/ajprenal.00234.2004","article-title":"Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions","volume":"289","author":"Schiffer","year":"2005","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib45","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1002\/jcb.22090","article-title":"Expression of GLUT8 in mouse intestine: identification of alternative spliced variants","volume":"106","author":"Romero","year":"2009","journal-title":"J. Cell. Biochem."},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib46","doi-asserted-by":"crossref","first-page":"4181","DOI":"10.1210\/en.2012-1541","article-title":"Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization","volume":"153","author":"DeBosch","year":"2012","journal-title":"Endocrinology"},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib47","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1007\/s00424-020-02417-x","article-title":"Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease","volume":"472","author":"Chadt","year":"2020","journal-title":"Pflueg. Arch. Eur. J. Physiol."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib48","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.tvjl.2015.05.018","article-title":"AICAR administration affects glucose metabolism by upregulating the novel glucose transporter, GLUT8, in equine skeletal muscle","volume":"205","author":"de Laat","year":"2015","journal-title":"Vet. J."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib49","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s13105-019-00679-3","article-title":"GLUT1 and GLUT8 support lactose synthesis in Golgi of murine mammary epithelial cells","volume":"75","author":"Villagr\u00e1n","year":"2019","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.bbrc.2026.153676_bib50","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1475-2840-11-63","article-title":"GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle","volume":"11","author":"Aerni-Flessner","year":"2012","journal-title":"Cardiovasc. Diabetol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib51","doi-asserted-by":"crossref","first-page":"C153","DOI":"10.1152\/ajpcell.00140.2022","article-title":"Getting sweeter: new evidence for glucose transporters in specific cell types of the airway?","volume":"324","author":"Baines","year":"2023","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib52","doi-asserted-by":"crossref","first-page":"717","DOI":"10.3390\/metabo15110717","article-title":"Altered pulmonary glucose transport is restored by metformin treatment in an Obese type 2 diabetic animal model","volume":"15","author":"Campolo","year":"2025","journal-title":"Metabolites"},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib53","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/s00239-002-2330-4","article-title":"Identification and phylogenetic analysis of a glucose transporter gene family from the human pathogenic yeast Candida albicans","volume":"55","author":"Fan","year":"2002","journal-title":"J. Mol. Evol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib54","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0016-6480(03)00145-X","article-title":"Broiler chickens (Ross strain) lack insulin-responsive glucose transporter GLUT4 and have GLUT8 cDNA","volume":"133","author":"Seki","year":"2003","journal-title":"Gen. Comp. Endocrinol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib55","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.bbaexp.2004.09.001","article-title":"Bovine glucose transporter GLUT8: cloning, expression, and developmental regulation in mammary gland","volume":"1680","author":"Zhao","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib56","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.acthis.2017.07.004","article-title":"Expression of glucose transporter 8 (GLUT8) in spermatogenesis of adult boar testes","volume":"119","author":"Xi","year":"2017","journal-title":"Acta Histochem."},{"issue":"Pt 1","key":"10.1016\/j.bbrc.2026.153676_bib57","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1042\/BJ20050887","article-title":"AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain","volume":"391","author":"M\u00eeinea","year":"2005","journal-title":"Biochem. J."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib58","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/cne.10368","article-title":"Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus","volume":"452","author":"Piroli","year":"2002","journal-title":"J. Comp. Neurol."},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib59","doi-asserted-by":"crossref","first-page":"4727","DOI":"10.1210\/en.2005-0668","article-title":"GLUT8 subcellular localization and absence of translocation to the plasma membrane in PC12 cells and hippocampal neurons","volume":"146","author":"Widmer","year":"2005","journal-title":"Endocrinology"},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib60","doi-asserted-by":"crossref","first-page":"4268","DOI":"10.1128\/MCB.00081-06","article-title":"GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function","volume":"26","author":"Membrez","year":"2006","journal-title":"Mol. Cell Biol."},{"issue":"16","key":"10.1016\/j.bbrc.2026.153676_bib61","doi-asserted-by":"crossref","first-page":"10989","DOI":"10.1074\/jbc.M113.527002","article-title":"Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis","volume":"289","author":"DeBosch","year":"2014","journal-title":"J. Biol. Chem."},{"issue":"suppl_2","key":"10.1016\/j.bbrc.2026.153676_bib62","doi-asserted-by":"crossref","DOI":"10.1161\/circ.130.suppl_2.15940","article-title":"Abstract 15940: calcium and insulin regulate the novel glucose transporter 8 (GLUT8) in the healthy and diabetic myocardium","volume":"130","author":"Martinez","year":"2014","journal-title":"Circulation"},{"issue":"S1","key":"10.1016\/j.bbrc.2026.153676_bib63","doi-asserted-by":"crossref","DOI":"10.1096\/fasebj.2020.34.s1.04878","article-title":"Metformin treatment rescues alterations of insulin\u2010sensitive glucose transporters in the lung of type 2 diabetic mice during H1N1 influenza infection","volume":"34","author":"Campolo","year":"2020","journal-title":"FASEB J."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib64","doi-asserted-by":"crossref","first-page":"E614","DOI":"10.1152\/ajpendo.91019.2008","article-title":"GLUT8, the enigmatic intracellular hexose transporter","volume":"296","author":"Schmidt","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbrc.2026.153676_bib65","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.bbrc.2021.06.037","article-title":"Cell-specific expression of functional glucose transporter 8 in mammary gland","volume":"567","author":"Mardones","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"Pt 11","key":"10.1016\/j.bbrc.2026.153676_bib66","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1242\/jcs.02943","article-title":"Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex","volume":"119","author":"Schmidt","year":"2006","journal-title":"J. Cell Sci."},{"issue":"8","key":"10.1016\/j.bbrc.2026.153676_bib67","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.2337\/diabetes.48.8.1667","article-title":"5\u2019 AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle","volume":"48","author":"Kurth-Kraczek","year":"1999","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib147","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/evj.12320","article-title":"The impact of prolonged hyperinsulinaemia on glucose transport in equine skeletal muscle and digital lamellae","volume":"47","author":"De Laat","year":"2015","journal-title":"Equine Vet. J."},{"key":"10.1016\/j.bbrc.2026.153676_bib82","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3389\/fcvm.2020.00134","article-title":"Insulin treatment reduces susceptibility to atrial fibrillation in type 1 diabetic mice","volume":"7","author":"Maria","year":"2020","journal-title":"Front. Cardiovasc. Med."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib68","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1530\/REP-19-0251","article-title":"Adiponectin stimulates glucose uptake in mouse blastocysts and embryonic carcinoma cells","volume":"159","author":"Burku\u0161","year":"2020","journal-title":"Reproduction"},{"key":"10.1016\/j.bbrc.2026.153676_bib69","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101451","article-title":"Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis","volume":"58","author":"Lee","year":"2022","journal-title":"Mol. Metabol."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib70","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.bbrc.2019.05.017","article-title":"Trehalose intake and exercise upregulate a glucose transporter, GLUT8, in the brain","volume":"514","author":"Narita","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib71","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s10519-008-9208-1","article-title":"Deletion of glucose transporter GLUT8 in mice increases locomotor activity","volume":"38","author":"Schmidt","year":"2008","journal-title":"Behav. Genet."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib72","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1469-7580.2011.01410.x","article-title":"Glucose transporters GLUT4 and GLUT8 are upregulated after facial nerve axotomy in adult mice","volume":"219","author":"G\u00f3mez","year":"2011","journal-title":"J. Anat."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib73","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1111\/andr.12097","article-title":"Reproductive function in male patients with type 1 diabetes mellitus","volume":"3","author":"La Vignera","year":"2015","journal-title":"Andrology"},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib74","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1080\/09687680701855405","article-title":"Targeted disruption of Slc2a8 (GLUT8) reduces motility and mitochondrial potential of spermatozoa","volume":"25","author":"Gawlik","year":"2008","journal-title":"Mol. Membr. Biol."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib75","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1152\/physrev.00038.2012","article-title":"Exercise, GLUT4, and skeletal muscle glucose uptake","volume":"93","author":"Richter","year":"2013","journal-title":"Physiol. Rev."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib76","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1249\/01.mss.0000222837.74015.f1","article-title":"Glucose transporter expression in skeletal muscle of endurance-trained individuals","volume":"38","author":"Seki","year":"2006","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.bbrc.2026.153676_bib77","doi-asserted-by":"crossref","DOI":"10.1038\/srep38586","article-title":"SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy","volume":"6","author":"Mayer","year":"2016","journal-title":"Sci. Rep."},{"issue":"8","key":"10.1016\/j.bbrc.2026.153676_bib78","doi-asserted-by":"crossref","first-page":"5641","DOI":"10.1074\/jbc.M609532200","article-title":"Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein","volume":"282","author":"Sarkar","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"6545","key":"10.1016\/j.bbrc.2026.153676_bib79","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/377151a0","article-title":"Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4","volume":"377","author":"Katz","year":"1995","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib80","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1074\/jbc.M108280200","article-title":"A phosphatidylinositol 3-kinase-independent insulin signaling pathway to N-WASP\/Arp2\/3\/F-actin required for GLUT4 glucose transporter recycling","volume":"277","author":"Jiang","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib81","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.bbadis.2015.01.009","article-title":"Sarcoplasmic reticulum Ca2+ ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart","volume":"1852","author":"Waller","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"issue":"4 Pt A","key":"10.1016\/j.bbrc.2026.153676_bib83","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.bbadis.2017.12.038","article-title":"Dysregulation of insulin-sensitive glucose transporters during insulin resistance-induced atrial fibrillation","volume":"1864","author":"Maria","year":"2018","journal-title":"Biochim. Biophys. Acta, Mol. Basis Dis."},{"issue":"1\u20132","key":"10.1016\/j.bbrc.2026.153676_bib84","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.vetimm.2013.10.010","article-title":"Toll-like receptor and pro-inflammatory cytokine expression during prolonged hyperinsulinaemia in horses: implications for laminitis","volume":"157","author":"De Laat","year":"2014","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib85","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0142077","article-title":"Loss of toll-like receptor 4 function partially protects against peripheral and cardiac glucose metabolic derangements during a long-term high-fat diet","volume":"10","author":"Jackson","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib86","doi-asserted-by":"crossref","first-page":"R237","DOI":"10.1152\/ajpregu.00093.2014","article-title":"Differential regulation of GLUT1 and GLUT8 expression by hypoxia in mammary epithelial cells","volume":"307","author":"Shao","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib87","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1095\/biolreprod.111.097675","article-title":"Slc2a8 deficiency in mice results in reproductive and growth impairments","volume":"87","author":"Adastra","year":"2012","journal-title":"Biol. Reprod."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib88","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1055\/s-0028-1128146","article-title":"Expression and regulation of insulin and the glucose transporter GLUT8 in the testes of diabetic rats","volume":"41","author":"G\u00f3mez","year":"2009","journal-title":"Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib89","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.102071","article-title":"Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega oxidation","volume":"24","author":"Novelle","year":"2021","journal-title":"iScience"},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib90","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1038\/modpathol.3800656","article-title":"GLUT1 and GLUT8 in endometrium and endometrial adenocarcinoma","volume":"19","author":"Goldman","year":"2006","journal-title":"Mod. Pathol.: An Official Journal of the United States and Canadian Academy of Pathology, Inc"},{"issue":"1\u20132","key":"10.1016\/j.bbrc.2026.153676_bib91","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1006\/mgme.2001.3212","article-title":"Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1","volume":"74","author":"Dawson","year":"2001","journal-title":"Mol. Genet. Metabol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib92","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1006\/geno.2000.6457","article-title":"Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility","volume":"72","author":"McVie-Wylie","year":"2001","journal-title":"Genomics"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib93","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1387\/ijdb.103179nc","article-title":"Characterization and expression pattern analysis of the facilitative glucose transporter 10 gene (slc2a10) in Danio rerio","volume":"55","author":"Chiarelli","year":"2011","journal-title":"Int. J. Dev. Biol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib94","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0006-291X(03)01322-6","article-title":"Expression of class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues","volume":"308","author":"Wood","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2026.153676_bib95","article-title":"Localization of glucose transporter 10 to hair cells' cuticular plate in the mouse inner ear","volume":"2018","author":"Chen","year":"2018","journal-title":"BioMed Res. Int."},{"issue":"S1","key":"10.1016\/j.bbrc.2026.153676_bib96","doi-asserted-by":"crossref","DOI":"10.1096\/fasebj.2019.33.1_supplement.lb572","article-title":"Insulin treatment rescues alterations in the lung following H1N1 influenza virus infection in diabetic mice","volume":"33","author":"Campolo","year":"2019","journal-title":"FASEB J."},{"issue":"1\u20132","key":"10.1016\/j.bbrc.2026.153676_bib97","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.mce.2008.05.003","article-title":"Expression analysis of facilitative glucose transporters (GLUTs) in human thyroid carcinoma cell lines and primary tumors","volume":"291","author":"Ciampi","year":"2008","journal-title":"Mol. Cell. Endocrinol."},{"issue":"19","key":"10.1016\/j.bbrc.2026.153676_bib98","doi-asserted-by":"crossref","first-page":"3721","DOI":"10.1093\/hmg\/ddq286","article-title":"Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome","volume":"19","author":"Lee","year":"2010","journal-title":"Hum. Mol. Genet."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib99","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/hmg\/ddx401","article-title":"GLUT10 maintains the integrity of major arteries through regulation of redox homeostasis and mitochondrial function","volume":"27","author":"Syu","year":"2018","journal-title":"Hum. Mol. Genet."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib100","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1093\/hmg\/ddr555","article-title":"GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGF\u03b2 signaling","volume":"21","author":"Willaert","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbrc.2026.153676_bib101","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.trsl.2023.05.001","article-title":"Glut10 restrains neointima formation by promoting SMCs mtDNA demethylation and improving mitochondrial function","volume":"260","author":"Wu","year":"2023","journal-title":"Transl. Res.: J. Lab. Clin. Med."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib102","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008823","article-title":"Glucose transporter 10 modulates adipogenesis via an ascorbic acid-mediated pathway to protect mice against diet-induced metabolic dysregulation","volume":"16","author":"Jiang","year":"2020","journal-title":"PLoS Genet."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib103","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.2337\/db16-1075","article-title":"GLUT4 is not necessary for overload-induced glucose uptake or hypertrophic growth in mouse skeletal muscle","volume":"66","author":"McMillin","year":"2017","journal-title":"Diabetes"},{"issue":"23","key":"10.1016\/j.bbrc.2026.153676_bib104","doi-asserted-by":"crossref","first-page":"4665","DOI":"10.1007\/s00018-014-1635-y","article-title":"Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid","volume":"71","author":"Garnett","year":"2014","journal-title":"Cell. Mol. Life Sci.: CMLS"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib105","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0016166","article-title":"Glucose depletion in the airway surface liquid is essential for sterility of the airways","volume":"6","author":"Pezzulo","year":"2011","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib106","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1093\/hmg\/ddaa071","article-title":"Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects","volume":"29","author":"Boel","year":"2020","journal-title":"Hum. Mol. Genet."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib107","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/ng1764","article-title":"Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome","volume":"38","author":"Coucke","year":"2006","journal-title":"Nat. Genet."},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib108","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1089\/ars.2019.7843","article-title":"Arterial tortuosity syndrome: an ascorbate compartmentalization disorder?","volume":"34","author":"Boel","year":"2021","journal-title":"Antioxidants Redox Signal."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib109","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2174\/1389201020666190613152030","article-title":"Comprehensive in silico study of GLUT10: prediction of possible substrate binding sites and interacting molecules","volume":"21","author":"Hosen","year":"2020","journal-title":"Curr. Pharm. Biotechnol."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib110","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/ng1511","article-title":"A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2","volume":"37","author":"Loeys","year":"2005","journal-title":"Nat. Genet."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib111","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e13836","article-title":"GLUT10 is a novel immune regulator involved in lung cancer immune cell infiltration and predicts worse survival when transcriptionally downregulated","volume":"9","author":"Jian","year":"2023","journal-title":"Heliyon"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib112","first-page":"469","article-title":"H22954, a long non-coding RNA, inhibits glucose uptake in leukemia cells in a GLUT10-dependent manner","volume":"27","author":"Bai","year":"2022","journal-title":"Hematology (Amsterdam, Netherlands)"},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib113","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/pro.2858","article-title":"GLUT, SGLT, and SWEET: structural and mechanistic investigations of the glucose transporters","volume":"25","author":"Deng","year":"2016","journal-title":"Protein Sci.: A Publication of the Protein Society"},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib114","doi-asserted-by":"crossref","first-page":"E733","DOI":"10.1152\/ajpendo.2002.282.3.E733","article-title":"Identification of a novel glucose transporter-like protein-GLUT-12","volume":"282","author":"Rogers","year":"2002","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib115","doi-asserted-by":"crossref","first-page":"E1067","DOI":"10.1152\/ajpendo.00250.2006","article-title":"Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle","volume":"291","author":"Stuart","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib116","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1939-1676.2010.0674.x","article-title":"Insulin resistance selectively alters cell-surface glucose transporters but not their total protein expression in equine skeletal muscle","volume":"25","author":"Waller","year":"2011","journal-title":"J. Vet. Intern. Med."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib117","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.bbadis.2012.09.013","article-title":"GLUT12 functions as a basal and insulin-independent glucose transporter in the heart","volume":"1832","author":"Waller","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib118","first-page":"7","article-title":"Avian and Mammalian facilitative glucose transporters","volume":"6","author":"Byers","year":"2017","journal-title":"Microarrays (Basel, Switzerland)"},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib119","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s00335-005-0080-5","article-title":"Cloning and expression of bovine glucose transporter GLUT12. Mammalian Genome","volume":"16","author":"Miller","year":"2005","journal-title":"Official Journal of the International Mammalian Genome Society"},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib120","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1083\/jcb.121.6.1221","article-title":"GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration","volume":"121","author":"Piper","year":"1993","journal-title":"J. Cell Biol."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib121","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1016\/S0021-9258(17)41949-1","article-title":"A Leu-Leu sequence is essential for COOH-terminal targeting signal of GLUT4 glucose transporter in fibroblasts","volume":"269","author":"Verhey","year":"1994","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib122","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev.biochem.72.121801.161800","article-title":"Signals for sorting of transmembrane proteins to endosomes and lysosomes","volume":"72","author":"Bonifacino","year":"2003","journal-title":"Annu. Rev. Biochem."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib123","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0955-0674(00)00235-0","article-title":"Adaptor-related proteins","volume":"13","author":"Robinson","year":"2001","journal-title":"Curr. Opin. Cell Biol."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib124","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1600-0854.2008.00866.x","article-title":"Similar [DE]XXXL[LI] motifs differentially target GLUT8 and GLUT12 in Chinese hamster ovary cells","volume":"10","author":"Flessner","year":"2009","journal-title":"Traffic (Copenhagen, Denmark)"},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib125","doi-asserted-by":"crossref","first-page":"R1300","DOI":"10.1152\/ajpregu.00822.2010","article-title":"Chronic heart failure selectively induces regional heterogeneity of insulin-responsive glucose transporters","volume":"301","author":"Ware","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib126","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0304-3835(03)00010-7","article-title":"Differential expression of GLUT12 in breast cancer and normal breast tissue","volume":"193","author":"Rogers","year":"2003","journal-title":"Cancer Lett."},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib127","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.1210\/jc.2009-0162","article-title":"Insulin-stimulated translocation of glucose transporter (GLUT) 12 parallels that of GLUT4 in normal muscle","volume":"94","author":"Stuart","year":"2009","journal-title":"J. Clin. Endocrinol. Metabol."},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib128","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.bbadis.2011.02.007","article-title":"Naturally occurring compensated insulin resistance selectively alters glucose transporters in visceral and subcutaneous adipose tissues without change in AS160 activation","volume":"1812","author":"Waller","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib129","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13283","article-title":"GLUT12 and adipose tissue: expression, regulation and its relation with obesity in mice","volume":"226","author":"Gil-Iturbe","year":"2019","journal-title":"Acta Physiologica (Oxford, England)"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib130","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.placenta.2004.04.006","article-title":"Expression of GLUT12 in the fetal membranes of the human placenta","volume":"26","author":"Gude","year":"2005","journal-title":"Placenta"},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib131","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1053\/plac.2002.0925","article-title":"GLUT12 expression in human placenta in first trimester and term","volume":"24","author":"Gude","year":"2003","journal-title":"Placenta"},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib132","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1530\/ERC-17-0051","article-title":"GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling","volume":"25","author":"White","year":"2018","journal-title":"Endocr. Relat. Cancer"},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib133","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/jb\/mvaa090","article-title":"Functional characterization and tissue localization of the facilitative glucose transporter GLUT12","volume":"168","author":"Matsuo","year":"2020","journal-title":"J. Biochem."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib134","doi-asserted-by":"crossref","first-page":"4396","DOI":"10.1002\/jcp.27231","article-title":"GLUT12 expression and regulation in murine small intestine and human Caco-2 cells","volume":"234","author":"Gil-Iturbe","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib135","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00441-002-0661-5","article-title":"Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland","volume":"311","author":"Macheda","year":"2003","journal-title":"Cell Tissue Res."},{"issue":"12","key":"10.1016\/j.bbrc.2026.153676_bib136","doi-asserted-by":"crossref","first-page":"C1008","DOI":"10.1152\/ajpcell.00343.2014","article-title":"Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods","volume":"308","author":"Pujol-Gim\u00e9nez","year":"2015","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib137","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1177\/0148607104028005364","article-title":"The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function","volume":"28","author":"Scheepers","year":"2004","journal-title":"JPEN - J. Parenter. Enter. Nutr."},{"issue":"Supl. 22","key":"10.1016\/j.bbrc.2026.153676_bib138","article-title":"Sarcoplasmic Reticulum calcium handling regulates glucose Transporter-4, but Not-12, trafficking in the healthy and diabetic myocardium","volume":"128","author":"Waller","year":"2013","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.bbrc.2026.153676_bib139","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1139\/apnm-2019-0721","article-title":"Effect of aging and obesity on GLUT12 expression in small intestine, adipose tissue, muscle, and kidney and its regulation by docosahexaenoic acid and exercise in mice","volume":"45","author":"Gil-Iturbe","year":"2020","journal-title":"Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme"},{"issue":"5","key":"10.1016\/j.bbrc.2026.153676_bib140","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.2337\/db11-0033","article-title":"Improved insulin sensitivity by GLUT12 overexpression in mice","volume":"60","author":"Purcell","year":"2011","journal-title":"Diabetes"},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib141","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.modgep.2004.04.010","article-title":"Identification of the facilitative glucose transporter 12 gene Glut12 in mouse preimplantation embryos","volume":"4","author":"Zhou","year":"2004","journal-title":"Gene Expr. Patterns: GEP"},{"issue":"31","key":"10.1016\/j.bbrc.2026.153676_bib142","doi-asserted-by":"crossref","first-page":"18175","DOI":"10.1073\/pnas.2006958117","article-title":"Identification of GLUT12\/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice","volume":"117","author":"Toyoda","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib143","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.103642","article-title":"Identification of an exporter that regulates vitamin C supply from blood to the brain","volume":"25","author":"Miyata","year":"2022","journal-title":"iScience"},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib144","doi-asserted-by":"crossref","first-page":"104","DOI":"10.7150\/ijbs.75106","article-title":"Inhibition of androgen receptor enhanced the anticancer effects of everolimus through targeting glucose transporter 12","volume":"19","author":"Cao","year":"2023","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1530\/JOE-14-0539","article-title":"GLUT12 deficiency during early development results in heart failure and a diabetic phenotype in zebrafish","volume":"224","author":"Jim\u00e9nez-Amilburu","year":"2015","journal-title":"J. Endocrinol."},{"issue":"10","key":"10.1016\/j.bbrc.2026.153676_bib146","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/nri1937","article-title":"Adipocytokines: mediators linking adipose tissue, inflammation and immunity","volume":"6","author":"Tilg","year":"2006","journal-title":"Nat. Rev. Immunol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib148","doi-asserted-by":"crossref","first-page":"139","DOI":"10.7150\/jca.10429","article-title":"Could GLUT12 be a potential therapeutic target in cancer treatment? A preliminary report","volume":"6","author":"Pujol-Gimenez","year":"2015","journal-title":"J. Cancer"},{"key":"10.1016\/j.bbrc.2026.153676_bib149","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.canlet.2020.09.012","article-title":"Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect","volume":"495","author":"Shi","year":"2020","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib150","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-52169-7","article-title":"UGCG influences glutamine metabolism of breast cancer cells","volume":"9","author":"Sch\u00f6mel","year":"2019","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib151","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1002\/jcp.20166","article-title":"Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer","volume":"202","author":"Macheda","year":"2005","journal-title":"J. Cell. Physiol."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib152","doi-asserted-by":"crossref","first-page":"904","DOI":"10.2967\/jnumed.119.231068","article-title":"Differential expression of glucose transporters and hexokinases in prostate cancer with a neuroendocrine gene signature: a mechanistic perspective for18 F-FDG imaging of PSMA-suppressed tumors","volume":"61","author":"Bakht","year":"2020","journal-title":"J. Nucl. Med."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib153","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s13105-024-01028-9","article-title":"The glucose transporter GLUT12, a new actor in obesity and cancer","volume":"81","author":"Burgos","year":"2025","journal-title":"J. Physiol. Biochem."},{"issue":"10","key":"10.1016\/j.bbrc.2026.153676_bib154","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s11626-021-00635-w","article-title":"Epithelial mesenchymal transition regulator TWIST1 transcription factor stimulates glucose uptake through upregulation of GLUT1, GLUT3, and GLUT12 in vitro","volume":"57","author":"Pehlivanoglu","year":"2021","journal-title":"Vitro Anim. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib155","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3233\/JAD-132498","article-title":"Expression of the glucose transporter GLUT12 in Alzheimer's disease patients","volume":"42","author":"Pujol-Gimenez","year":"2014","journal-title":"J. Alzheimers Dis.: JAD"},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib156","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1007\/s12035-019-01743-1","article-title":"GLUT12 expression in brain of mouse models of alzheimer's disease","volume":"57","author":"Gil-Iturbe","year":"2020","journal-title":"Mol. Neurobiol."},{"issue":"16","key":"10.1016\/j.bbrc.2026.153676_bib157","doi-asserted-by":"crossref","first-page":"4467","DOI":"10.1093\/emboj\/20.16.4467","article-title":"Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain","volume":"20","author":"Uldry","year":"2001","journal-title":"EMBO J."},{"issue":"3","key":"10.1016\/j.bbrc.2026.153676_bib158","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/sj.emboj.7600072","article-title":"Regulated exocytosis of an H+\/myo-inositol symporter at synapses and growth cones","volume":"23","author":"Uldry","year":"2004","journal-title":"EMBO J."},{"issue":"16","key":"10.1016\/j.bbrc.2026.153676_bib159","doi-asserted-by":"crossref","first-page":"5866","DOI":"10.3390\/ijerph17165866","article-title":"Transcriptional profiling and biological pathway(s) analysis of type 2 diabetes mellitus in a Pakistani population","volume":"17","author":"Noreen","year":"2020","journal-title":"Int. J. Environ. Res. Publ. Health"},{"issue":"28","key":"10.1016\/j.bbrc.2026.153676_bib160","doi-asserted-by":"crossref","first-page":"15530","DOI":"10.1021\/acs.jafc.4c01550","article-title":"Novel circular RNA CircSLC2A13 regulates chicken muscle development by sponging MiR-34a-3p","volume":"72","author":"Jiao","year":"2024","journal-title":"J. Agric. Food Chem."},{"issue":"7","key":"10.1016\/j.bbrc.2026.153676_bib161","doi-asserted-by":"crossref","first-page":"3204","DOI":"10.1021\/acs.molpharmaceut.3c01210","article-title":"Transporter protein expression of corneal epithelium in rabbit and porcine: evaluation of models for ocular drug transport study","volume":"21","author":"Ramsay","year":"2024","journal-title":"Mol. Pharm."},{"issue":"10","key":"10.1016\/j.bbrc.2026.153676_bib162","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.febslet.2015.03.012","article-title":"Inositol transport proteins","volume":"589","author":"Schneider","year":"2015","journal-title":"FEBS Letters"},{"issue":"Pt 5","key":"10.1016\/j.bbrc.2026.153676_bib163","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1042\/BST0371139","article-title":"Investigation of the H(+)-myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling","volume":"37","author":"Di Daniel","year":"2009","journal-title":"Biochem. Soc. Trans."},{"issue":"4","key":"10.1016\/j.bbrc.2026.153676_bib164","first-page":"481","article-title":"Distinct prognostic values of the mRNA expression of glucose transporters in non-small cell lung cancer","volume":"50","author":"Du","year":"2020","journal-title":"ACLS (Ann. Clin. Lab. Sci.)"},{"key":"10.1016\/j.bbrc.2026.153676_bib165","doi-asserted-by":"crossref","DOI":"10.1177\/1533033819894308","article-title":"The solute carrier family 2 genes are potential prognostic biomarkers in acute myeloid leukemia","volume":"19","author":"Lai","year":"2020","journal-title":"Technol. Cancer Res. Treat."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib166","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s10020-024-00988-4","article-title":"Lipid metabolism-related gene signature predicts prognosis and unveils novel anti-tumor drugs in specific type of diffuse large B cell lymphoma","volume":"30","author":"Wang","year":"2024","journal-title":"Mol. Med."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib167","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/s41531-024-00722-1","article-title":"High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson's disease","volume":"10","author":"Wang","year":"2024","journal-title":"npj Parkinson's Dis."},{"key":"10.1016\/j.bbrc.2026.153676_bib168","doi-asserted-by":"crossref","first-page":"152.e1","DOI":"10.1016\/j.neurobiolaging.2021.02.022","article-title":"Mutation analysis of seven SLC family transporters for early-onset Parkinson's disease in Chinese population","volume":"103","author":"Li","year":"2021","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.bbrc.2026.153676_bib169","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2024.123203","article-title":"Long-standing preservation of levodopa response in progressive supranuclear palsy","volume":"466","author":"Sano","year":"2024","journal-title":"J. Neurol. Sci."},{"issue":"17","key":"10.1016\/j.bbrc.2026.153676_bib170","doi-asserted-by":"crossref","first-page":"3438","DOI":"10.1111\/febs.13353","article-title":"Proton myo\u2010inositol cotransporter is a novel \u03b3\u2010secretase associated protein that regulates A\u03b2 production without affecting Notch cleavage","volume":"282","author":"Teranishi","year":"2015","journal-title":"FEBS J."},{"issue":"1","key":"10.1016\/j.bbrc.2026.153676_bib171","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/s12931-023-02421-6","article-title":"Inositol possesses antifibrotic activity and mitigates pulmonary fibrosis","volume":"24","author":"Li","year":"2023","journal-title":"Respir. Res."},{"key":"10.1016\/j.bbrc.2026.153676_bib172","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1030238","article-title":"Inositol alleviates pulmonary fibrosis by promoting autophagy via inhibiting the HIF-1\u03b1-SLUG axis in acute respiratory distress syndrome","volume":"2022","author":"Liang","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.bbrc.2026.153676_bib173","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.720784","article-title":"Restoration of mRNA expression of solute carrier proteins in liver of diet-induced Obese mice by metformin","volume":"12","author":"Le","year":"2021","journal-title":"Front. Endocrinol."},{"issue":"2","key":"10.1016\/j.bbrc.2026.153676_bib174","doi-asserted-by":"crossref","first-page":"e875","DOI":"10.1210\/clinem\/dgaa814","article-title":"Placental inositol reduced in gestational diabetes as glucose alters inositol transporters and IMPA1 enzyme expression","volume":"106","author":"Pillai","year":"2021","journal-title":"J. Clin. Endocrinol. Metabol."},{"issue":"11","key":"10.1016\/j.bbrc.2026.153676_bib175","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1007\/s11427-019-1563-3","article-title":"Regulation of glucose and lipid metabolism in health and disease. Science China","volume":"62","author":"Chen","year":"2019","journal-title":"Life Sci."},{"issue":"6","key":"10.1016\/j.bbrc.2026.153676_bib176","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2024.119748","article-title":"Protein kinase-D1 and downstream signaling mechanisms involved in GLUT4 translocation in cardiac muscle","volume":"1871","author":"Simsek Papur","year":"2024","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"issue":"33","key":"10.1016\/j.bbrc.2026.153676_bib177","doi-asserted-by":"crossref","first-page":"17271","DOI":"10.1074\/jbc.M116.730168","article-title":"Mammalian glucose transporter activity is dependent upon anionic and conical phospholipids","volume":"291","author":"Hresko","year":"2016","journal-title":"J. Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26004407?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26004407?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T05:30:55Z","timestamp":1793597455000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X26004407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":177,"alternative-id":["S0006291X26004407"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.153676","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Class III facilitative glucose transporters: Beyond glucose transport in health and disease","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.153676","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"153676"}}