{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T19:50:41Z","timestamp":1785873041725,"version":"3.56.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012669","name":"Natural Science Foundation Project of Chongqing","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004374","name":"Chongqing Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing Municipality","doi-asserted-by":"publisher","award":["CSTB2024NSCQ-MSX0658"],"award-info":[{"award-number":["CSTB2024NSCQ-MSX0658"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.bbrc.2026.154123","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T15:45:14Z","timestamp":1780933514000},"page":"154123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Ultrasound-triggered self-assembled cascade nanozymes for ROS-mediated synergistic chemodynamic therapy"],"prefix":"10.1016","volume":"828","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0373-6213","authenticated-orcid":false,"given":"Ziwei","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2026.154123_bib1","first-page":"177","article-title":"Fenton metal nanomedicines for imaging-guided combinatorial chemodynamic therapy against cancer","volume":"17","author":"Liu","year":"2022","journal-title":"Asian J. Pharm. Sci."},{"key":"10.1016\/j.bbrc.2026.154123_bib2","doi-asserted-by":"crossref","first-page":"11683","DOI":"10.1021\/acsami.1c01006","article-title":"A three-in-one ZIFs-Derived CuCo(O)\/GOx@PCNs hybrid Cascade nanozyme for Immunotherapy\/enhanced starvation\/photothermal therapy","volume":"13","author":"Wang","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bbrc.2026.154123_bib3","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202006892","article-title":"Nanocatalytic theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient cancer therapy","volume":"33","author":"Fu","year":"2021","journal-title":"Adv. Mater. (Deerfield Beach, Fla.)"},{"key":"10.1016\/j.bbrc.2026.154123_bib4","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.biomaterials.2019.03.014","article-title":"Ultrasmall CuS nanodots as photothermal-enhanced Fenton nanocatalysts for synergistic tumor therapy at NIR-II biowindow","volume":"206","author":"Hu","year":"2019","journal-title":"Biomaterials"},{"key":"10.1016\/j.bbrc.2026.154123_bib5","doi-asserted-by":"crossref","first-page":"15513","DOI":"10.1039\/D0CC05427E","article-title":"Nanoenzymes in disease diagnosis and therapy","volume":"56","author":"Yu","year":"2020","journal-title":"Chem. Commun. (Cambridge, England)"},{"key":"10.1016\/j.bbrc.2026.154123_bib6","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s40820-022-00828-2","article-title":"Nanozymes: versatile platforms for cancer diagnosis and therapy","volume":"14","author":"Zhang","year":"2022","journal-title":"Nano-Micro Lett."},{"key":"10.1016\/j.bbrc.2026.154123_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2025.152249","article-title":"Recent advances in nanopharmaceutical strategies for cancer treatment","volume":"777","author":"Khalid","year":"2025","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2026.154123_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2026.153417","article-title":"Editorial: Nanomedicine \u2013 from bench to bedside","volume":"806","author":"Alexiou","year":"2026","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbrc.2026.154123_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201901819","article-title":"Glutathione-depleting nanoenzyme and glucose oxidase combination for hypoxia modulation and radiotherapy enhancement","volume":"9","author":"Lyu","year":"2020","journal-title":"Adv. Healthcare Mater."},{"key":"10.1016\/j.bbrc.2026.154123_bib10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jcis.2021.03.173","article-title":"One-pot synthesis of a self-reinforcing cascade bioreactor for combined photodynamic\/chemodynamic\/starvation therapy","volume":"599","author":"Zhang","year":"2021","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.bbrc.2026.154123_bib11","article-title":"Polypyrrole nanoenzymes as tumor microenvironment modulators to reprogram macrophage and potentiate immunotherapy","volume":"9","author":"Zeng","year":"2022","journal-title":"Adv. Sci. (Weinheim, Baden-Wurttemberg, Germany)"},{"key":"10.1016\/j.bbrc.2026.154123_bib12","article-title":"A Glucose\/oxygen-exhausting nanoreactor for Starvation- and hypoxia-activated sustainable and Cascade chemo-chemodynamic therapy","volume":"16","author":"Guo","year":"2020","journal-title":"Small"},{"key":"10.1016\/j.bbrc.2026.154123_bib13","article-title":"Multienzyme-like nanozymes: regulation, rational design, and application","author":"Sheng","year":"2023","journal-title":"Adv. Mater. (Deerfield Beach, Fla.)"},{"key":"10.1016\/j.bbrc.2026.154123_bib14","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s42114-025-01411-0","article-title":"Ultrasound-activated dual-nanozyme platform for targeted ROS scavenging and NO delivery in liver fibrosis therapy","volume":"8","author":"Yin","year":"2025","journal-title":"Adv. Compos. Hybrid Mater."},{"key":"10.1016\/j.bbrc.2026.154123_bib15","doi-asserted-by":"crossref","first-page":"102796","DOI":"10.1016\/j.mtbio.2026.102796","article-title":"Ultrasound-responsive hydrogel with ROS scavenging and NO controllable release capabilities for accelerated healing of diabetic wounds","volume":"37","author":"Luo","year":"2026","journal-title":"Mater. Today Bio"},{"key":"10.1016\/j.bbrc.2026.154123_bib16","article-title":"Ultrasmall alloy nanozyme for Ultrasound- and near-infrared light-promoted tumor ablation","volume":"15","author":"Deblin","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.bbrc.2026.154123_bib17","doi-asserted-by":"crossref","first-page":"7774","DOI":"10.1021\/acsnano.1c01830","article-title":"Ultrasmall alloy nanozyme for Ultrasound- and near-infrared light-promoted tumor ablation","volume":"15","author":"Jana","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.bbrc.2026.154123_bib18","article-title":"Ultrasound-augmented multienzyme-like nanozyme hydrogel spray for promoting diabetic wound healing","volume":"17","author":"Limin","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.bbrc.2026.154123_bib19","doi-asserted-by":"crossref","first-page":"11764","DOI":"10.1002\/anie.201807595","article-title":"Hybrid nanoreactors: enabling an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy","volume":"57","author":"Yang","year":"2018","journal-title":"Angewandte Chemie (International ed. in English)"},{"key":"10.1016\/j.bbrc.2026.154123_bib20","article-title":"Sono-activated artificial vanadium enzyme system for efficient and renewable reactive oxygen nanobiocatalytic therapies","author":"Wu","year":"2026","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bbrc.2026.154123_bib21","article-title":"ROS self-supply nanoplatform based on fenton catalyst for chemodynamic and immunotherapy: reprogramming cold tumor into hot tumor in cancer treatment","author":"Lee","year":"2026","journal-title":"Adv. Sci. (Weinheim, Baden-Wurttemberg, Germany)"},{"key":"10.1016\/j.bbrc.2026.154123_bib22","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/s11671-026-04587-6","article-title":"Low-frequency ultrasound-assisted application of Ag\/Cu nanocomposites as a promising strategy for the treatment of purulent wounds","volume":"21","author":"Myronov","year":"2026","journal-title":"Discov. Nano"},{"key":"10.1016\/j.bbrc.2026.154123_bib23","doi-asserted-by":"crossref","first-page":"4950","DOI":"10.1039\/D3NA00427A","article-title":"Rapid and sensitive detection of alkaline phosphatase and glucose oxidase activity through fluorescence and colorimetric dual-mode analysis based on CuO NPs@ZIF-8 mediated enzyme-cascade reactions","volume":"5","author":"GuoYing","year":"2023","journal-title":"Nanoscale Adv."},{"key":"10.1016\/j.bbrc.2026.154123_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.150131","article-title":"Photothermal\/Photodynamic synergistic antibacterial study of MOF nanoplatform with SnFe2O4 as the core","volume":"720","author":"Zhang","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26008879?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26008879?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T19:41:27Z","timestamp":1785872487000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X26008879"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":24,"alternative-id":["S0006291X26008879"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.154123","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ultrasound-triggered self-assembled cascade nanozymes for ROS-mediated synergistic chemodynamic therapy","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.154123","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"154123"}}