{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T09:30:21Z","timestamp":1793784621876,"version":"4.6.1"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,10,10]],"date-time":"2027-10-10T00:00:00Z","timestamp":1823126400000},"content-version":"am","delay-in-days":343,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100025019","name":"Support for Pioneering Research Initiated by the Next Generation","doi-asserted-by":"publisher","award":["JPMJSP2110"],"award-info":[{"award-number":["JPMJSP2110"]}],"id":[{"id":"10.13039\/501100025019","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22H02199"],"award-info":[{"award-number":["JP22H02199"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP16H06313"],"award-info":[{"award-number":["JP16H06313"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP23H04934"],"award-info":[{"award-number":["JP23H04934"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP26K21965"],"award-info":[{"award-number":["JP26K21965"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP21H04954"],"award-info":[{"award-number":["JP21H04954"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP26K03292"],"award-info":[{"award-number":["JP26K03292"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP23K23466"],"award-info":[{"award-number":["JP23K23466"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP21K18324"],"award-info":[{"award-number":["JP21K18324"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP24K21340"],"award-info":[{"award-number":["JP24K21340"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP18H02089"],"award-info":[{"award-number":["JP18H02089"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22H00585"],"award-info":[{"award-number":["JP22H00585"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.bbrc.2026.154718","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T23:10:59Z","timestamp":1791501059000},"page":"154718","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Feedback-controlled single-frequency microwave thermal cycling enables dynamic modulation of liposome membrane permeability"],"prefix":"10.1016","volume":"839","author":[{"given":"Yunting","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchen","family":"Sha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikaru","family":"Takaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Mizuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunari","family":"Akiyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrc.2026.154718_bib1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.addr.2018.06.017","article-title":"Strategic design of extracellular vesicle drug delivery systems","volume":"130","author":"Armstrong","year":"2018","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.bbrc.2026.154718_bib2","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/s41580-022-00460-3","article-title":"Challenges and directions in studying cell\u2013cell communication by extracellular vesicles","volume":"23","author":"van Niel","year":"2022","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.bbrc.2026.154718_bib3","doi-asserted-by":"crossref","first-page":"7617","DOI":"10.1039\/D4NR04778H","article-title":"Recent advances in functional lipid-based nanomedicines as drug carriers for organ-specific delivery","volume":"17","author":"Yun","year":"2025","journal-title":"Nanoscale"},{"key":"10.1016\/j.bbrc.2026.154718_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2023.102930","article-title":"Advanced liposome and polymersome-based drug delivery systems: considerations for physicochemical properties, targeting strategies and stimuli-sensitive approaches","volume":"317","author":"Kans\u0131z","year":"2023","journal-title":"Adv. Colloid Interface Sci."},{"key":"10.1016\/j.bbrc.2026.154718_bib5","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jconrel.2013.03.036","article-title":"Thermosensitive liposomes for localized delivery and triggered release of chemotherapy","volume":"169","author":"Ta","year":"2013","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.bbrc.2026.154718_bib6","doi-asserted-by":"crossref","first-page":"4581","DOI":"10.1016\/j.bpj.2009.01.062","article-title":"The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics","volume":"96","author":"Blicher","year":"2009","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbrc.2026.154718_bib7","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0169-409X(01)00233-2","article-title":"The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors","volume":"53","author":"Needham","year":"2001","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.bbrc.2026.154718_bib8","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/0005-2736(73)90314-3","article-title":"Phase transitions in phospholipid vesicles: fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol","volume":"311","author":"Papahadjopoulos","year":"1973","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.bbrc.2026.154718_bib9","doi-asserted-by":"crossref","first-page":"7826","DOI":"10.1021\/acs.langmuir.5b01878","article-title":"Clean photothermal heating and controlled release from near-infrared dye doped nanoparticles without oxygen photosensitization","volume":"31","author":"Guha","year":"2015","journal-title":"Langmuir"},{"key":"10.1016\/j.bbrc.2026.154718_bib10","article-title":"Influence of phase transitions on diffusive molecular transport across biological membranes","volume":"61","author":"Wu","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bbrc.2026.154718_bib11","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1016\/S0006-3495(95)80415-7","article-title":"Permeability of dimyristoyl phosphatidylcholine\/dipalmitoyl phosphatidylcholine bilayer membranes with coexisting gel and liquid-crystalline phases","volume":"68","author":"Clerc","year":"1995","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbrc.2026.154718_bib12","doi-asserted-by":"crossref","first-page":"266","DOI":"10.2307\/3576581","article-title":"Microwave-stimulated drug release from liposomes","volume":"103","author":"Liburdy","year":"1985","journal-title":"Radiat. Res."},{"key":"10.1016\/j.bbrc.2026.154718_bib13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/bem.2250090306","article-title":"Effects of 2.45-GHz microwave and 100-MHz radiofrequency radiation on liposome permeability at the phase transition temperature","volume":"9","author":"Liu","year":"1988","journal-title":"Bioelectromagnetics"},{"key":"10.1016\/j.bbrc.2026.154718_bib14","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1021\/acs.bioconjchem.6b00603","article-title":"Microwave-triggered smart drug release from liposomes co-encapsulating doxorubicin and salt for local combined hyperthermia and chemotherapy of cancer","volume":"27","author":"Jin","year":"2016","journal-title":"Bioconjug. Chem."},{"key":"10.1016\/j.bbrc.2026.154718_bib15","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1002\/mop.33689","article-title":"0.5 kWatt 2.45 GHz GaN-based microwave heating system design with active phase control","volume":"65","author":"Ahn","year":"2023","journal-title":"Microw. Opt. Technol. Lett."},{"key":"10.1016\/j.bbrc.2026.154718_bib16","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1587\/transele.2024MMI0004","article-title":"GaN solid state power amplifiers for microwave power transfer and microwave heating","author":"Yamanaka","year":"2024","journal-title":"IEICE Trans. Electron."},{"key":"10.1016\/j.bbrc.2026.154718_bib17","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1016\/j.bpj.2010.08.029","article-title":"Cell-penetrating peptide induces leaky fusion of liposomes containing late endosome-specific anionic lipid","volume":"99","author":"Yang","year":"2010","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbrc.2026.154718_bib18","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.bbamem.2004.12.007","article-title":"Calorimetric and spectroscopic studies of the phase behavior and organization of lipid bilayer model membranes composed of binary mixtures of dimyristoylphosphatidylcholine and dimyristoylphosphatidylglycerol","volume":"1668","author":"Lewis","year":"2005","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.bbrc.2026.154718_bib19","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1038\/s41598-025-32211-7","article-title":"Phosphatidylserine exposure on tolerogenic nanoparticle correlate with oral tolerance","volume":"16","author":"Chak","year":"2026","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbrc.2026.154718_bib20","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202312898","article-title":"Phospholipid membranes as chemically and functionally tunable materials","volume":"36","author":"Huster","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bbrc.2026.154718_bib21","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1016\/S0006-3495(04)74227-7","article-title":"Molecular dynamics simulation of a palmitoyl-oleoyl phosphatidylserine bilayer with Na+ counterions and NaCl","volume":"86","author":"Mukhopadhyay","year":"2004","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbrc.2026.154718_bib22","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1039\/a827213z","article-title":"Dielectric parameters relevant to microwave dielectric heating","volume":"27","author":"Gabriel","year":"1998","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bbrc.2026.154718_bib23","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.bbamem.2009.04.006","article-title":"The response of giant phospholipid vesicles to millimeter waves radiation","volume":"1788","author":"Ramundo-Orlando","year":"2009","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.bbrc.2026.154718_bib24","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0167-7322(84)80028-8","article-title":"On the changes in the microwave dielectric spectrum of aqueous phospholipid bilayer solutions at the ordered-fluid phase transition","volume":"28","author":"Kaatze","year":"1984","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.bbrc.2026.154718_bib25","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/0005-2736(73)90314-3","article-title":"Phase transitions in phospholipid vesicles: fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol","volume":"311","author":"Papahadjopoulos","year":"1973","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.bbrc.2026.154718_bib26","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.bpj.2022.12.007","article-title":"Molecular simulations and NMR reveal how lipid fluctuations affect membrane mechanics","volume":"122","author":"Doktorova","year":"2023","journal-title":"Biophys. J."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26014841?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X26014841?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T08:59:55Z","timestamp":1793782795000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X26014841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":26,"alternative-id":["S0006291X26014841"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.154718","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Feedback-controlled single-frequency microwave thermal cycling enables dynamic modulation of liposome membrane permeability","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrc.2026.154718","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"154718"}}