{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:34:29Z","timestamp":1770813269532,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T00:00:00Z","timestamp":1478563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004051","name":"Kato Memorial Bioscience Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005865","name":"Mochida Memorial Foundation for Medical and Pharmaceutical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011746","name":"NOVARTIS Foundation (Japan) for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011746","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemistry and Biophysics Reports"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.bbrep.2016.11.001","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T00:31:01Z","timestamp":1478737861000},"page":"29-35","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis"],"prefix":"10.1016","volume":"9","author":[{"given":"Takeshi","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Fukaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomofumi","family":"Uto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Arimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Tono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuaki","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbrep.2016.11.001_bib1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/B978-0-12-394299-9.00005-9","article-title":"Functional heterogeneity in the basophil cell lineage","volume":"115","author":"Siracusa","year":"2012","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1126\/science.1221064","article-title":"New paradigms in type 2 immunity","volume":"337","author":"Pulendran","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.bbrep.2016.11.001_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coi.2014.07.004","article-title":"Basophils have emerged as a key player in immunity","volume":"31","author":"Karasuyama","year":"2014","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib4","doi-asserted-by":"crossref","first-page":"7744","DOI":"10.4049\/jimmunol.172.12.7744","article-title":"CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules","volume":"172","author":"Gorczynski","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib5","doi-asserted-by":"crossref","first-page":"54117","DOI":"10.1074\/jbc.M406997200","article-title":"CD200 receptor family members represent novel DAP12-associated activating receptors on basophils and mast cells","volume":"279","author":"Voehringer","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbrep.2016.11.001_bib6","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.4049\/jimmunol.171.6.3034","article-title":"Characterization of the CD200 receptor family in mice and humans and their interactions with CD200","volume":"171","author":"Wright","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib7","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.4049\/jimmunol.175.4.2469","article-title":"Recombinant CD200 protein does not bind activating proteins closely related to CD200 receptor","volume":"175","author":"Hatherley","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib8","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1126\/science.290.5497.1768","article-title":"Down-regulation of the macrophage lineage through interaction with OX2 (CD200)","volume":"290","author":"Hoek","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.bbrep.2016.11.001_bib9","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S1471-4906(02)02223-8","article-title":"CD200 and membrane protein interactions in the control of myeloid cells","volume":"23","author":"Barclay","year":"2002","journal-title":"Trends Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib10","doi-asserted-by":"crossref","first-page":"6786","DOI":"10.4049\/jimmunol.173.11.6786","article-title":"Molecular mechanisms of CD200 inhibition of mast cell activation","volume":"173","author":"Zhang","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib11","doi-asserted-by":"crossref","first-page":"4441","DOI":"10.4049\/jimmunol.175.7.4441","article-title":"Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200","volume":"175","author":"Shiratori","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib12","doi-asserted-by":"crossref","first-page":"7093","DOI":"10.4049\/jimmunol.179.10.7093","article-title":"Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner","volume":"179","author":"Kojima","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib13","doi-asserted-by":"crossref","first-page":"4780","DOI":"10.1182\/blood-2008-10-183145","article-title":"Naturally occurring regulatory dendritic cells regulate murine cutaneous chronic graft-versus-host disease","volume":"113","author":"Sato","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.bbrep.2016.11.001_bib14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.2332\/allergolint.08-RAI-0059","article-title":"New insights into the roles for basophils in acute and chronic allergy","volume":"58","author":"Mukai","year":"2009","journal-title":"Allergol. Int."},{"key":"10.1016\/j.bbrep.2016.11.001_bib15","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1600-065X.2011.01028.x","article-title":"Anaphylaxis: a history with emphasis on food allergy","volume":"242","author":"Boden","year":"2011","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.bbrep.2016.11.001_bib16","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.immuni.2008.02.008","article-title":"Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis","volume":"28","author":"Tsujimura","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.bbrep.2016.11.001_bib17","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1083\/jcb.200501111","article-title":"Fc\u03b5RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane","volume":"170","author":"Nishida","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbrep.2016.11.001_bib18","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1007\/s00018-015-1870-x","article-title":"The role of Fc\u03b5RI expressed in dendritic cells and monocytes","volume":"72","author":"Shin","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbrep.2016.11.001_bib19","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1182\/blood-2007-01-068718","article-title":"Basophils are essential initiators of a novel type of chronic allergic inflammation","volume":"110","author":"Obata","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.bbrep.2016.11.001_bib20","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.immuni.2010.08.011","article-title":"Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths","volume":"33","author":"Ohnmacht","year":"2010","journal-title":"Immunity"}],"container-title":["Biochemistry and Biophysics Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580816302849?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405580816302849?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:39:21Z","timestamp":1762501161000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405580816302849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":20,"alternative-id":["S2405580816302849"],"URL":"https:\/\/doi.org\/10.1016\/j.bbrep.2016.11.001","relation":{},"ISSN":["2405-5808"],"issn-type":[{"value":"2405-5808","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis","name":"articletitle","label":"Article Title"},{"value":"Biochemistry and Biophysics Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbrep.2016.11.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}